Salmonella typhimurium activates virulence gene transcription within acidified macrophage phagosomes

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Salmonella typhimurium activates virulence gene transcription within acidified macrophage phagosomes is …
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scholarly articleQ13442814

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P819ADS bibcode1992PNAS...8910079A
P356DOI10.1073/PNAS.89.21.10079
P8608Fatcat IDrelease_3xxc6i6gqfgo7fdt5gti27qwua
P932PMC publication ID50281
P698PubMed publication ID1438196
P5875ResearchGate publication ID21717914

P2093author name stringS I Miller
J A Swanson
W P Loomis
C M Alpuche Aranda
P2860cites workProtein phosphorylation and regulation of adaptive responses in bacteriaQ24634755
A Salmonella typhimurium virulence protein is similar to a Yersinia enterocolitica invasion protein and a bacteriophage lambda outer membrane proteinQ24681193
The ability of Salmonella to enter mammalian cells is affected by bacterial growth stateQ33616743
A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence.Q34286908
Salmonella typhimurium phoP virulence gene is a transcriptional regulatorQ34303992
Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agentsQ34556950
PhoP/PhoQ: macrophage-specific modulators ofSalmonellavirulence?Q34657622
Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulentQ35617117
Inducible pH homeostasis and the acid tolerance response of Salmonella typhimuriumQ36151300
Adaptive acidification tolerance response of Salmonella typhimurium.Q36158004
Constitutive expression of the phoP regulon attenuates Salmonella virulence and survival within macrophagesQ36162205
Temporal changes of lysosome and phagosome pH during phagolysosome formation in macrophages: studies by fluorescence spectroscopyQ36204862
Acidification of phagosomes is initiated before lysosomal enzyme activity is detectedQ36207809
Ammonium chloride, an inhibitor of phagosome-lysosome fusion in macrophages, concurrently induces phagosome-endosome fusion, and opens a novel pathway: studies of a pathogenic mycobacterium and a nonpathogenic yeastQ36230420
Suppressor mutations in rpoA suggest that OmpR controls transcription by direct interaction with the alpha subunit of RNA polymeraseQ36241595
Mechanisms of acquired resistance in mouse typhoidQ36268345
Fluorescent labeling of endocytic compartments.Q38196885
Coordinate regulation and sensory transduction in the control of bacterial virulenceQ38265611
Genetic regulation of bacterial virulenceQ38763408
Manipulations of the phagosome-lysosome fusion response in cultured macrophages. Enhancement of fusion by chloroquine and other aminesQ39613217
Inhibition of macrophage phagosome-lysosome fusion by Salmonella typhimuriumQ40150964
Phagolysosome Formation, Cyclic Adenosine 3':5'-Monophosphate and the Fate of Salmonella typhimurium within Mouse Peritoneal MacrophagesQ40225458
Multiple beta 1 chain integrins are receptors for invasin, a protein that promotes bacterial penetration into mammalian cellsQ41511934
Comparison of the invasion strategies used by Salmonella cholerae-suis, Shigella flexneri and Yersinia enterocolitica to enter cultured animal cells: endosome acidification is not required for bacterial invasion or intracellular replicationQ41516620
Probing the phagolysosomal environment of human macrophages with a Ca2+-responsive operon fusion in Yersinia pestisQ41521947
Involvement of the epidermal growth factor receptor in the invasion of cultured mammalian cells by Salmonella typhimuriumQ41619060
Induction of Salmonella stress proteins upon infection of macrophagesQ41734412
Transitory cis complementation: a method for providing transposition functions to defective transposons.Q42960575
Specific inhibition of phagosome-lysosome fusion in murine macrophages mediated by Salmonella typhimurium infection.Q50465236
Reticulum cell sarcoma: an effector cell in antibody-dependent cell-mediated immunityQ66892185
Phorbol esters stimulate macropinocytosis and solute flow through macrophagesQ69428411
P433issue21
P407language of work or nameEnglishQ1860
P921main subjectSalmonella TyphimuriumQ166491
macrophageQ184204
P304page(s)10079-10083
P577publication date1992-11-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleSalmonella typhimurium activates virulence gene transcription within acidified macrophage phagosomes
P478volume89

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Q24548929The pleiotropic two-component regulatory system PhoP-PhoQ
Q38574548The revival of interest in mechanisms of bacterial pathogenicity
Q35545890The unique trafficking pattern of Salmonella typhimurium-containing phagosomes in murine macrophages is independent of the mechanism of bacterial entry
Q42641210The use of differential display-PCR to isolate and characterize a Legionella pneumophila locus induced during the intracellular infection of macrophages
Q44518273Tolerance to stress and ability of acid-adapted and non-acid-adapted Salmonella enterica serovar Typhimurium DT104 to invade and survive in mammalian cells in vitro
Q34557132Trafficking of the Salmonella vacuole in macrophages
Q34424785Transcriptional Profiling of a Cross-Protective Salmonella enterica serovar Typhimurium UK-1 dam Mutant Identifies a Set of Genes More Transcriptionally Active Compared to Wild-Type, and Stably Transcribed across Biologically Relevant Microenvironme
Q64241526Transcriptional Sequencing Uncovers Survival Mechanisms of Salmonella enterica Serovar Enteritidis in Antibacterial Egg White
Q35616130Transcriptional regulation of Salmonella virulence: a PhoQ periplasmic domain mutation results in increased net phosphotransfer to PhoP.
Q39843585Two-component regulatory systems can interact to process multiple environmental signals
Q33693791Two-component signal transduction as a target for microbial anti-infective therapy
Q42905654Unsaturated long chain free fatty acids are input signals of the Salmonella enterica PhoP/PhoQ regulatory system
Q50114722Unusual intracellular trafficking of Salmonella typhimurium in human melanoma cells
Q39538269Vacuole acidification is not required for survival of Salmonella enterica serovar typhimurium within cultured macrophages and epithelial cells
Q35480919Vesicles containing Chlamydia trachomatis serovar L2 remain above pH 6 within HEC-1B cells
Q34298435Visualization of vacuolar acidification-induced transcription of genes of pathogens inside macrophages
Q41307220What happens in vivo to bacterial pathogens?
Q93127599YaeB, Expressed in Response to the Acidic pH in Macrophages, Promotes Intracellular Replication and Virulence of Salmonella Typhimurium
Q35573520pH-regulated activation and release of a bacteria-associated phospholipase C during intracellular infection by Listeria monocytogenes

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