Identification and genetic characterization of PmrA-regulated genes and genes involved in polymyxin B resistance in Salmonella enterica serovar typhimurium

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Identification and genetic characterization of PmrA-regulated genes and genes involved in polymyxin B resistance in Salmonella enterica serovar typhimurium is …
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scholarly articleQ13442814

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P356DOI10.1128/IAI.70.12.6770-6778.2002
P932PMC publication ID133008
P698PubMed publication ID12438352

P2093author name stringRita Tamayo
John S Gunn
Andrea J McCoy
Sara S Ryan
P2860cites workComplete genome sequence of Salmonella enterica serovar Typhimurium LT2Q22122369
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Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteriaQ28344828
Construction of versatile low-copy-number vectors for cloning, sequencing and gene expression in Escherichia coliQ29615309
Lipid A modifications characteristic of Salmonella typhimurium are induced by NH4VO3 in Escherichia coli K12. Detection of 4-amino-4-deoxy-L-arabinose, phosphoethanolamine and palmitateQ30717098
Molecular characterization of the locus encoding biosynthesis of the lipopolysaccharide O antigen of Escherichia coli serotype O113Q30798461
Ca2+-induced phosphoethanolamine transfer to the outer 3-deoxy-D-manno-octulosonic acid moiety of Escherichia coli lipopolysaccharide. A novel membrane enzyme dependent upon phosphatidylethanolamineQ30947622
Lipid A modifications in polymyxin-resistant Salmonella typhimurium: PMRA-dependent 4-amino-4-deoxy-L-arabinose, and phosphoethanolamine incorporationQ31006759
An inner membrane enzyme in Salmonella and Escherichia coli that transfers 4-amino-4-deoxy-L-arabinose to lipid A: induction on polymyxin-resistant mutants and role of a novel lipid-linked donorQ31006859
Accumulation of a polyisoprene-linked amino sugar in polymyxin-resistant Salmonella typhimurium and Escherichia coli: structural characterization and transfer to lipid A in the periplasmQ31006874
How intracellular bacteria survive: surface modifications that promote resistance to host innate immune responses.Q33542356
The Tol proteins of Escherichia coli and their involvement in the uptake of biomolecules and outer membrane stabilityQ33726872
Mutations in each of the tol genes of Pseudomonas putida reveal that they are critical for maintenance of outer membrane stabilityQ33791027
A novel, rapid method for the isolation of terminal sequences from yeast artificial chromosome (YAC) clonesQ33912732
Antibiotic peptides as mediators of innate immunityQ33987884
Phosphorylated PmrA interacts with the promoter region of ugd in Salmonella enterica serovar typhimuriumQ33994345
Constitutive mutations of the Salmonella enterica serovar Typhimurium transcriptional virulence regulator phoPQ34004885
Genetic and functional analysis of a PmrA-PmrB-regulated locus necessary for lipopolysaccharide modification, antimicrobial peptide resistance, and oral virulence of Salmonella enterica serovar typhimuriumQ34004929
Salmonella enterica serovar typhimurium waaP mutants show increased susceptibility to polymyxin and loss of virulence In vivoQ34007636
Oxidative decarboxylation of UDP-glucuronic acid in extracts of polymyxin-resistant Escherichia coli. Origin of lipid a species modified with 4-amino-4-deoxy-L-arabinoseQ34101511
Antibiotic proteins of human neutrophilsQ34262671
A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence.Q34286908
Protegrin-1: a broad-spectrum, rapidly microbicidal peptide with in vivo activity.Q35137651
Agents that increase the permeability of the outer membrane.Q35403079
SurA assists the folding of Escherichia coli outer membrane proteinsQ35604222
The TolB protein interacts with the porins of Escherichia coliQ35632817
Binding of polymyxin B nonapeptide to gram-negative bacteriaQ35642509
Bacterial infection as assessed by in vivo gene expressionQ35966527
Molecular basis of the magnesium deprivation response in Salmonella typhimurium: identification of PhoP-regulated genesQ36812913
Lipid A acylation and bacterial resistance against vertebrate antimicrobial peptides.Q36899142
Lipopolysaccharide structure determines ionic and hydrophobic binding of a cationic antimicrobial neutrophil granule proteinQ36996921
O antigen and lipid A phosphoryl groups in resistance of Salmonella typhimurium LT-2 to nonoxidative killing in human polymorphonuclear neutrophilsQ37007295
Cationic antimicrobial proteins isolated from human neutrophil granulocytes in the presence of diisopropyl fluorophosphateQ37076566
Defensins: endogenous antibiotic peptides of animal cellsQ37625789
Identification by genetic suppression of Escherichia coli TolB residues important for TolB-Pal interactionQ39498889
RegA, iron, and growth phase regulate expression of the Pseudomonas aeruginosa tol-oprL gene clusterQ39587011
Salmonella enterica serovar typhimurium resistance to bile: identification and characterization of the tolQRA clusterQ39678359
Involvement of the oxidative pentose phosphate pathway in thiamine biosynthesis in Salmonella typhimuriumQ39840534
Two-component regulatory systems can interact to process multiple environmental signalsQ39843585
PhoP-PhoQ activates transcription of pmrAB, encoding a two-component regulatory system involved in Salmonella typhimurium antimicrobial peptide resistanceQ39843622
Regulation of polymyxin resistance and adaptation to low-Mg2+ environmentsQ39847917
Increased outer membrane resistance to ethylenediaminetetraacetate and cations in novel lipid A mutantsQ39971212
Decreased binding of polymyxin by polymyxin-resistant mutants of Salmonella typhimuriumQ39973551
A small protein that mediates the activation of a two-component system by another two-component systemQ40370371
Antimicrobial peptides as agents of mucosal immunity.Q40537896
Isolation and characterization of lipopolysaccharides, lipooligosaccharides, and lipid A.Q40687425
Genetics of pentose-phosphate pathway enzymes of Escherichia coli K-12.Q40952270
Transitory cis complementation: a method for providing transposition functions to defective transposons.Q42960575
TolB protein of Escherichia coli K-12 interacts with the outer membrane peptidoglycan-associated proteins Pal, Lpp and OmpA.Q47694282
PmrA-PmrB-regulated genes necessary for 4-aminoarabinose lipid A modification and polymyxin resistanceQ48038471
Isolation and characterization of the Haemophilus influenzae tolQ, tolR, tolA and tolB genesQ48058687
A signal transduction system that responds to extracellular ironQ50118677
Molecular characterization of the PmrA regulon.Q50124709
Increased substitution of phosphate groups in lipopolysaccharides and lipid A of the polymyxin-resistant pmrA mutants of Salmonella typhimurium: a 31P-NMR studyQ50151855
Characterization of the lipopolysaccharide from the polymyxin-resistantpmrAmutants ofSalmonella typhimuriumQ50216500
Lipopolysaccharides of polymyxin B-resistant mutants of Escherichia coli are extensively substituted by 2-aminoethyl pyrophosphate and contain aminoarabinose in lipid A.Q54177184
Positive selection vectors for allelic exchange.Q54593431
Peptidoglycan-associated lipoprotein-TolB interaction. A possible key to explaining the formation of contact sites between the inner and outer membranes of Escherichia coli.Q54612320
Detergent-accelerated hydrolysis of bacterial endotoxins and determination of the anomeric configuration of the glycosyl phosphate present in the "isolated lipid A" fragment of the Bordetella pertussis endotoxinQ69922037
Import of colicins across the outer membrane of Escherichia coli involves multiple protein interactions in the periplasmQ77155308
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectSalmonella entericaQ2264864
P304page(s)6770-6778
P577publication date2002-12-01
P1433published inInfection and ImmunityQ6029193
P1476titleIdentification and genetic characterization of PmrA-regulated genes and genes involved in polymyxin B resistance in Salmonella enterica serovar typhimurium
P478volume70

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cites work (P2860)
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