A formyltransferase required for polymyxin resistance in Escherichia coli and the modification of lipid A with 4-Amino-4-deoxy-L-arabinose. Identification and function oF UDP-4-deoxy-4-formamido-L-arabinose

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A formyltransferase required for polymyxin resistance in Escherichia coli and the modification of lipid A with 4-Amino-4-deoxy-L-arabinose. Identification and function oF UDP-4-deoxy-4-formamido-L-arabinose is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M414265200
P698PubMed publication ID15695810

P2093author name stringAnthony A Ribeiro
Christian R H Raetz
Amanda L McClerren
Steven D Breazeale
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Lipid A modifications characteristic of Salmonella typhimurium are induced by NH4VO3 in Escherichia coli K12. Detection of 4-amino-4-deoxy-L-arabinose, phosphoethanolamine and palmitateQ30717098
A PhoP/PhoQ-induced Lipase (PagL) that catalyzes 3-O-deacylation of lipid A precursors in membranes of Salmonella typhimuriumQ30975949
Lipid A modifications in polymyxin-resistant Salmonella typhimurium: PMRA-dependent 4-amino-4-deoxy-L-arabinose, and phosphoethanolamine incorporationQ31006759
An inner membrane enzyme in Salmonella and Escherichia coli that transfers 4-amino-4-deoxy-L-arabinose to lipid A: induction on polymyxin-resistant mutants and role of a novel lipid-linked donorQ31006859
Accumulation of a polyisoprene-linked amino sugar in polymyxin-resistant Salmonella typhimurium and Escherichia coli: structural characterization and transfer to lipid A in the periplasmQ31006874
Structure of an acidic polysaccharide from a marine bacterium Pseudoalteromonas distincta KMM 638 containing 5-acetamido-3,5,7,9-tetradeoxy-7-formamido-L-glycero-L-manno-nonulosonic acidQ32059007
Crystal structure of methionyl-tRNAfMet transformylase complexed with the initiator formyl-methionyl-tRNAfMet.Q33890098
Genetic and functional analysis of a PmrA-PmrB-regulated locus necessary for lipopolysaccharide modification, antimicrobial peptide resistance, and oral virulence of Salmonella enterica serovar typhimuriumQ34004929
Oxidative decarboxylation of UDP-glucuronic acid in extracts of polymyxin-resistant Escherichia coli. Origin of lipid a species modified with 4-amino-4-deoxy-L-arabinoseQ34101511
A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence.Q34286908
The PmrA-regulated pmrC gene mediates phosphoethanolamine modification of lipid A and polymyxin resistance in Salmonella entericaQ34434883
Biochemistry of endotoxinsQ34564256
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Identification of genes involved in the sequestration of iron in mycobacteria: the ferric exochelin biosynthetic and uptake pathways.Q36719012
Regulation of lipid A modifications by Salmonella typhimurium virulence genes phoP-phoQ.Q36852656
Lipid A acylation and bacterial resistance against vertebrate antimicrobial peptides.Q36899142
PhoP-PhoQ activates transcription of pmrAB, encoding a two-component regulatory system involved in Salmonella typhimurium antimicrobial peptide resistanceQ39843622
Role of Mg2+ and pH in the modification of Salmonella lipid A after endocytosis by macrophage tumour cells.Q40469112
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Genetic organisation of the lipopolysaccharide O-antigen biosynthesis region of brucella melitensis 16M (wbk).Q43215069
Probing catalysis by Escherichia coli dTDP-glucose-4,6-dehydratase: identification and preliminary characterization of functional amino acid residues at the active siteQ43622638
A convenient synthesis of 4-amino-4-deoxy-L-arabinose and its reduction product, 1,4-dideoxy-1,4-imino-L-arabinitolQ43900505
Structure of the O-polysaccharide of Providencia alcalifaciens O21 containing 3-formamido-3,6-dideoxy-D-galactose.Q44474936
Structure of the O-antigen of Francisella tularensis strain 15.Q45052551
PmrA-PmrB-regulated genes necessary for 4-aminoarabinose lipid A modification and polymyxin resistanceQ48038471
High-resolution NMR spectroscopy of lipid A molecules containing 4-amino-4-deoxy-L-arabinose and phosphoethanolamine substituents. Different attachment sites on lipid A molecules from NH4VO3-treated Escherichia coli versus kdsA mutants of SalmonellaQ50121309
Increased substitution of phosphate groups in lipopolysaccharides and lipid A of the polymyxin-resistant pmrA mutants of Salmonella typhimurium: a 31P-NMR studyQ50151855
A rapid screen of active site mutants in glycinamide ribonucleotide transformylase.Q54585483
Subcloning, characterization, and affinity labeling of Escherichia coli glycinamide ribonucleotide transformylase.Q54717157
P433issue14
P407language of work or nameEnglishQ1860
P921main subject4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic processQ21761266
4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate metabolic processQ22282871
undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activityQ24510204
UDP-4-amino-4-deoxy-L-arabinose formyltransferase activityQ24510755
Escherichia coliQ25419
P304page(s)14154-14167
P577publication date2005-01-28
P1433published inJournal of Biological ChemistryQ867727
P1476titleA formyltransferase required for polymyxin resistance in Escherichia coli and the modification of lipid A with 4-Amino-4-deoxy-L-arabinose. Identification and function oF UDP-4-deoxy-4-formamido-L-arabinose
P478volume280

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