scholarly article | Q13442814 |
P50 | author | George N Phillips | Q95337388 |
Shanteri Singh | Q41112372 | ||
Jon S Thorson | Q41112392 | ||
P2860 | cites work | A genomic overview of pyridoxal-phosphate-dependent enzymes | Q24536053 |
Structure and function of both domains of ArnA, a dual function decarboxylase and a formyltransferase, involved in 4-amino-4-deoxy-L-arabinose biosynthesis | Q24596697 | ||
Biochemical and structural characterization of WlbA from Bordetella pertussis and Chromobacterium violaceum: enzymes required for the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid | Q24606876 | ||
Structure and mechanism of ArnA: conformational change implies ordered dehydrogenase mechanism in key enzyme for polymyxin resistance | Q24630632 | ||
A structural basis for the allosteric regulation of non-hydrolysing UDP-GlcNAc 2-epimerases | Q24646011 | ||
Crystal structure of Escherichia coli ArnA (PmrI) decarboxylase domain. A key enzyme for lipid A modification with 4-amino-4-deoxy-L-arabinose and polymyxin resistance | Q24646087 | ||
Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM | Q24646712 | ||
Crystal structure of the bifunctional N-acetylglucosamine 1-phosphate uridyltransferase from Escherichia coli: a paradigm for the related pyrophosphorylase superfamily | Q27619240 | ||
Structural and kinetic analysis of Escherichia coli GDP-mannose 4,6 dehydratase provides insights into the enzyme's catalytic mechanism and regulation by GDP-fucose | Q27621354 | ||
Redesign of polyene macrolide glycosylation: engineered biosynthesis of 19-(O)-perosaminyl-amphoteronolide B. | Q43147546 | ||
Molecular mechanisms of fosfomycin resistance in clinical isolates of Escherichia coli | Q43195414 | ||
Biological mechanisms involved in the formation of deoxy sugars. IV. Enzymatic conversion of thymidine diphosphoglucose-4T to thymidine diphospho-4-keto-6-deoxyglucose-6T. | Q43522503 | ||
Asparagine 23 and aspartate 305 are essential residues in the active site of UDP-N-acetylglucosamine enolpyruvyl transferase from Enterobacter cloacae | Q43591572 | ||
Mechanistic investigation of UDP-galactopyranose mutase from Escherichia coli using 2- and 3-fluorinated UDP-galactofuranose as probes | Q43670133 | ||
Bacterial modification of LPS and resistance to antimicrobial peptides | Q43718689 | ||
Regioselectivity of catechol O-methyltransferase. The effect of pH on the site of O-methylation of fluorinated norepinephrines | Q43843613 | ||
Genetic engineering of aminodeoxyhexose biosynthesis in Streptomyces fradiae | Q44044947 | ||
On the origin of deoxypentoses: evidence to support a glucose progenitor in the biosynthesis of calicheamicin | Q44197156 | ||
Role of the loop containing residue 115 in the induced-fit mechanism of the bacterial cell wall biosynthetic enzyme MurA | Q27621570 | ||
RmlC, the third enzyme of dTDP-L-rhamnose pathway, is a new class of epimerase | Q27622479 | ||
The crystal structure of ADP-L-glycero-D-mannoheptose 6-epimerase: catalysis with a twist | Q27625372 | ||
Probing the catalytic mechanism of GDP-4-keto-6-deoxy-d-mannose Epimerase/Reductase by kinetic and crystallographic characterization of site-specific mutants | Q27627359 | ||
The structure of UDP-N-acetylglucosamine 2-epimerase reveals homology to phosphoglycosyl transferases | Q27628806 | ||
The structural basis of the catalytic mechanism and regulation of glucose-1-phosphate thymidylyltransferase (RmlA) | Q27628928 | ||
Crystal structure of Streptococcus pneumoniae N-acetylglucosamine-1-phosphate uridyltransferase bound to acetyl-coenzyme A reveals a novel active site architecture | Q27628944 | ||
Crystal structures of Streptococcus pneumoniae N-acetylglucosamine-1-phosphate uridyltransferase, GlmU, in apo form at 2.33 A resolution and in complex with UDP-N-acetylglucosamine and Mg(2+) at 1.96 A resolution | Q27629008 | ||
The crystal structure of dTDP-D-Glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar Typhimurium, the second enzyme in the dTDP-l-rhamnose pathway | Q27630554 | ||
Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization | Q27632060 | ||
UDP-galactopyranose mutase has a novel structure and mechanism | Q27635026 | ||
Kinetic and crystallographic analyses support a sequential-ordered bi bi catalytic mechanism for Escherichia coli glucose-1-phosphate thymidylyltransferase | Q27636040 | ||
Toward a structural understanding of the dehydratase mechanism | Q27637363 | ||
Variation on a theme of SDR. dTDP-6-deoxy-L- lyxo-4-hexulose reductase (RmlD) shows a new Mg2+-dependent dimerization mode | Q27639149 | ||
Purification, crystallization and preliminary structural studies of dTDP-4-keto-6-deoxy-glucose-5-epimerase (EvaD) from Amycolatopsis orientalis, the fourth enzyme in the dTDP-L-epivancosamine biosynthetic pathway | Q27639207 | ||
Crystal structure of Escherichia coli glucose-1-phosphate thymidylyltransferase (RffH) complexed with dTTP and Mg2+ | Q27639485 | ||
Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering | Q27639760 | ||
Structural studies of Salmonella typhimurium ArnB (PmrH) aminotransferase: a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme | Q27639956 | ||
High resolution x-ray structure of tyvelose epimerase from Salmonella typhi | Q27640717 | ||
Structure and Dynamics of UDP–Glucose Pyrophosphorylase from Arabidopsis thaliana with Bound UDP–Glucose and UTP | Q27640844 | ||
High-resolution structures of RmlC from Streptococcus suis in complex with substrate analogs locate the active site of this class of enzyme | Q27641399 | ||
A new view of the mechanisms of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) and 5-enolpyruvylshikimate-3-phosphate synthase (AroA) derived from X-ray structures of their tetrahedral reaction intermediate states | Q27642065 | ||
The structure of NADH in the enzyme dTDP-d-glucose dehydratase (RmlB) | Q27642216 | ||
High resolution X-ray structure of dTDP-glucose 4,6-dehydratase from Streptomyces venezuelae | Q27642390 | ||
Crystal structure of a tetrameric GDP-D-mannose 4,6-dehydratase from a bacterial GDP-D-rhamnose biosynthetic pathway | Q27643014 | ||
The molecular architecture of glucose-1-phosphate uridylyltransferase | Q27643901 | ||
The Complex of Sphingomonas elodea ATCC 31461 Glucose-1-Phosphate Uridylyltransferase with Glucose-1-Phosphate Reveals a Novel Quaternary Structure, Unique among Nucleoside Diphosphate-Sugar Pyrophosphorylase Members | Q27644458 | ||
Molecular architecture of DesV fromStreptomyces venezuelae: A PLP-dependent transaminase involved in the biosynthesis of the unusual sugar desosamine | Q27644595 | ||
The x-ray structure of dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase | Q27644605 | ||
Structure of theE. colibifunctional GlmU acetyltransferase active site with substrates and products | Q27644659 | ||
Active site geometry of glucose-1-phosphate uridylyltransferase | Q27645792 | ||
Molecular Architecture of DesI: A Key Enzyme in the Biosynthesis of Desosamine † , ‡ | Q27646687 | ||
A Structural Study of GDP-4-Keto-6-Deoxy- d -Mannose-3-Dehydratase: Caught in the Act of Geminal Diamine Formation † , ‡ | Q27649009 | ||
Characterization of substrate binding and catalysis in the potential antibacterial targetN-acetylglucosamine-1-phosphate uridyltransferase (GlmU) | Q27649118 | ||
Enzymatic methods for glyco(diversification/randomization) of drugs and small molecules | Q28247479 | ||
Evolutionary trace analysis of the alpha-D-phosphohexomutase superfamily | Q28270568 | ||
Structure and functions of the GNAT superfamily of acetyltransferases | Q28296840 | ||
Mycobacterium tuberculosis RmlC epimerase (Rv3465): a promising drug-target structure in the rhamnose pathway | Q28486876 | ||
RmlC, a C3' and C5' carbohydrate epimerase, appears to operate via an intermediate with an unusual twist boat conformation | Q28490087 | ||
Many paths to methyltransfer: a chronicle of convergence | Q29616667 | ||
SAM (dependent) I AM: the S-adenosylmethionine-dependent methyltransferase fold | Q29618153 | ||
GCN5-related N-acetyltransferases: a structural overview | Q29619219 | ||
Pyridoxal phosphate enzymes: mechanistic, structural, and evolutionary considerations | Q29620045 | ||
Short-chain dehydrogenases/reductases (SDR) | Q29620095 | ||
Structure-based phylogeny as a diagnostic for functional characterization of proteins with a cupin fold | Q30157239 | ||
Evolution of functional diversity in the cupin superfamily. | Q30167749 | ||
Structural and mechanistic basis of bacterial sugar nucleotide-modifying enzymes. | Q30333015 | ||
Natural-product sugar biosynthesis and enzymatic glycodiversification | Q30492476 | ||
Characterization of enzymatic processes by rapid mix-quench mass spectrometry: the case of dTDP-glucose 4,6-dehydratase. | Q30961494 | ||
Molecular diversity through sugar scaffolds | Q30977448 | ||
Dehydration is catalyzed by glutamate-136 and aspartic acid-135 active site residues in Escherichia coli dTDP-glucose 4,6-dehydratase | Q31016682 | ||
Sweet antibiotics - the role of glycosidic residues in antibiotic and antitumor activity and their randomization | Q33353798 | ||
Carbohydrate scaffolds in chemical genetic studies | Q33470834 | ||
Combinatorial biosynthesis for new drug discovery | Q33538629 | ||
Carbohydrate mimetics and scaffolds: sweet spots in medicinal chemistry | Q33852360 | ||
Crystal structure of potato tuber ADP-glucose pyrophosphorylase | Q33868406 | ||
Structure and function of enzymes of the Leloir pathway for galactose metabolism | Q33967795 | ||
Galactokinase: structure, function and role in type II galactosemia | Q33982846 | ||
Molecular structure of human galactokinase: implications for type II galactosemia | Q33983696 | ||
Genetic and functional analysis of a PmrA-PmrB-regulated locus necessary for lipopolysaccharide modification, antimicrobial peptide resistance, and oral virulence of Salmonella enterica serovar typhimurium | Q34004929 | ||
The rhamnose pathway | Q34103415 | ||
Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria | Q34316342 | ||
A unique catalytic mechanism for UDP-galactopyranose mutase | Q34319532 | ||
The mechanism of the reaction catalyzed by ADP-beta-L-glycero-D-manno-heptose 6-epimerase | Q34334649 | ||
Chemical insights from structural studies of enzymes | Q34360265 | ||
Glycosides in medicine: "The role of glycosidic residue in biological activity". | Q34372899 | ||
Reaction specificity in pyridoxal phosphate enzymes | Q34373891 | ||
A formyltransferase required for polymyxin resistance in Escherichia coli and the modification of lipid A with 4-Amino-4-deoxy-L-arabinose. Identification and function oF UDP-4-deoxy-4-formamido-L-arabinose | Q34391736 | ||
Crystal structure and mechanism of the Escherichia coli ArnA (PmrI) transformylase domain. An enzyme for lipid A modification with 4-amino-4-deoxy-L-arabinose and polymyxin resistance | Q34408515 | ||
GDP-4-keto-6-deoxy-D-mannose 3-dehydratase, accommodating a sugar substrate in the active site | Q27649164 | ||
Structure and active site residues of PglD, an N-acetyltransferase from the bacillosamine synthetic pathway required for N-glycan synthesis in Campylobacter jejuni | Q27649543 | ||
Crystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamine and fosfomycin | Q27649770 | ||
GDP-perosamine synthase: structural analysis and production of a novel trideoxysugar | Q27649775 | ||
Three-dimensional structure of DesVI from Streptomyces venezuelae: a sugar N,N-dimethyltransferase required for dTDP-desosamine biosynthesis | Q27650032 | ||
Structural analysis of ADP-glucose pyrophosphorylase from the bacterium Agrobacterium tumefaciens | Q27650121 | ||
Crystal Structure and Catalytic Mechanism of PglD from Campylobacter jejuni | Q27651382 | ||
Accommodation of GDP-linked sugars in the active site of GDP-perosamine synthase | Q27652172 | ||
Structural Analysis of QdtB, an Aminotransferase Required for the Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-α- d -glucose † ‡ | Q27653599 | ||
Structural and Functional Studies of QdtC: An N -Acetyltransferase Required for the Biosynthesis of dTDP-3-Acetamido-3,6-dideoxy-α- d -glucose † ‡ | Q27653643 | ||
Structure and function of GlmU fromMycobacterium tuberculosis | Q27653924 | ||
Two Site-Directed Mutations Are Required for the Conversion of a Sugar Dehydratase into an Aminotransferase § | Q27655325 | ||
Structure ofN-acetylglucosamine-1-phosphate uridyltransferase (GlmU) fromMycobacterium tuberculosisin a cubic space group | Q27655339 | ||
Ligand Binding and Substrate Discrimination by UDP-Galactopyranose Mutase | Q27655753 | ||
X-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavin | Q27657238 | ||
Structural basis of substrate binding to UDP-galactopyranose mutase: crystal structures in the reduced and oxidized state complexed with UDP-galactopyranose and UDP | Q27657821 | ||
The Crystal Structure of the Novobiocin Biosynthetic Enzyme NovP: The First Representative Structure for the TylF O-Methyltransferase Superfamily | Q27657980 | ||
Evidence of kinetic control of ligand binding and staged product release in MurA (enolpyruvyl UDP-GlcNAc synthase)-catalyzed reactions | Q27658111 | ||
Structural basis for the reaction mechanism of UDP-glucose pyrophosphorylase | Q27660270 | ||
X-ray structure of kijd3, a key enzyme involved in the biosynthesis of D-kijanose | Q27660314 | ||
Structural and mechanistic basis for a new mode of glycosyltransferase inhibition | Q27660415 | ||
Molecular Structure of WlbB, a Bacterial N -Acetyltransferase Involved in the Biosynthesis of 2,3-Diacetamido-2,3-dideoxy- d -mannuronic Acid, | Q27661069 | ||
The crystal structure of the Y140F mutant of ADP-L-glycero-D-manno-heptose 6-epimerase bound to ADP-β-D-mannose suggests a one base mechanism | Q27661977 | ||
Molecular architecture of a C-3'-methyltransferase involved in the biosynthesis of D-tetronitrose | Q27662124 | ||
Structural Insights into the Catalytic Mechanism of Bacterial Guanosine-diphospho-D-mannose Pyrophosphorylase and Its Regulation by Divalent Ions | Q27662663 | ||
Structural Analysis of WbpE from Pseudomonas aeruginosa PAO1: A Nucleotide Sugar Aminotransferase Involved in O-Antigen Assembly, | Q27663161 | ||
Chemoenzymatic synthesis, inhibition studies, and X-ray crystallographic analysis of the phosphono analog of UDP-Galp as an inhibitor and mechanistic probe for UDP-galactopyranose mutase | Q27664551 | ||
Structure and mechanism of ORF36, an amino sugar oxidizing enzyme in everninomicin biosynthesis . | Q27664658 | ||
Molecular Architecture of TylM1 from Streptomyces fradiae : An N , N -Dimethyltransferase Involved in the Production of dTDP- d -mycaminose, | Q27666229 | ||
Expanding the Nucleotide and Sugar 1-Phosphate Promiscuity of Nucleotidyltransferase RmlA via Directed Evolution | Q27666946 | ||
Altered architecture of substrate binding region defines the unique specificity of UDP-GalNAc 4-epimerases | Q27667219 | ||
Combined structural and functional investigation of a C-3''-ketoreductase involved in the biosynthesis of dTDP-L-digitoxose | Q27667911 | ||
A New Structural Form in the SAM/Metal-Dependent O‑Methyltransferase Family: MycE from the Mycinamicin Biosynthetic Pathway | Q27672783 | ||
The crystal structure of ADP-L-glycero-D-manno-heptose-6-epimerase (HP0859) from Helicobacter pylori | Q27674767 | ||
Structural studies of AntD: an N-Acyltransferase involved in the biosynthesis of D-Anthrose | Q27676557 | ||
A left-handed parallel beta helix in the structure of UDP-N-acetylglucosamine acyltransferase | Q27729303 | ||
Towards structure-based drug design: crystal structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 A resolution | Q27730263 | ||
The structure of glucose-fructose oxidoreductase from Zymomonas mobilis: an osmoprotective periplasmic enzyme containing non-dissociable NADP | Q27734347 | ||
Structure of UDP-N-acetylglucosamine enolpyruvyl transferase, an enzyme essential for the synthesis of bacterial peptidoglycan, complexed with substrate UDP-N-acetylglucosamine and the drug fosfomycin | Q27734363 | ||
Structural analysis of the H166G site-directed mutant of galactose-1-phosphate uridylyltransferase complexed with either UDP-glucose or UDP-galactose: detailed description of the nucleotide sugar binding site | Q27734963 | ||
Structural analysis of UDP-sugar binding to UDP-galactose 4-epimerase from Escherichia coli | Q27738620 | ||
Mechanistic roles of tyrosine 149 and serine 124 in UDP-galactose 4-epimerase from Escherichia coli | Q27742332 | ||
Dramatic differences in the binding of UDP-galactose and UDP-glucose to UDP-galactose 4-epimerase from Escherichia coli | Q27765151 | ||
GDP-4-keto-6-deoxy-D-mannose epimerase/reductase from Escherichia coli, a key enzyme in the biosynthesis of GDP-L-fucose, displays the structural characteristics of the RED protein homology superfamily | Q27766039 | ||
GDP-fucose synthetase from Escherichia coli: structure of a unique member of the short-chain dehydrogenase/reductase family that catalyzes two distinct reactions at the same active site | Q27766387 | ||
Formation of unusual sugars: mechanistic studies and biosynthetic applications | Q28202326 | ||
Mechanistic roles of Thr134, Tyr160, and Lys 164 in the reaction catalyzed by dTDP-glucose 4,6-dehydratase | Q28209829 | ||
The calicheamicin gene cluster and its iterative type I enediyne PKS | Q28218405 | ||
Glycosyltransferase structural biology and its role in the design of catalysts for glycosylation | Q28238053 | ||
The mechanism of 6-deoxyhexose synthesis. I. Intramolecular hydrogen transfer catalyzed by deoxythymidine diphosphate D-glucose oxidoreductase | Q28246656 | ||
Reconstitution of UDP-galactopyranose mutase with 1-deaza-FAD and 5-deaza-FAD: analysis and mechanistic implications | Q44653012 | ||
The position of a key tyrosine in dTDP-4-Keto-6-deoxy-D-glucose-5-epimerase (EvaD) alters the substrate profile for this RmlC-like enzyme. | Q44907831 | ||
Active site mutants of the "non-hydrolyzing" UDP-N-acetylglucosamine 2-epimerase from Escherichia coli | Q44946645 | ||
Molecular structure of alpha-D-glucose-1-phosphate cytidylyltransferase from Salmonella typhi | Q45005968 | ||
Sch 37137, a novel antifungal compound produced by a Micromonospora sp. Taxonomy, fermentation, isolation, structure and biological properties. | Q45167698 | ||
Unusually broad substrate tolerance of a heat-stable archaeal sugar nucleotidyltransferase for the synthesis of sugar nucleotides | Q45177620 | ||
Characterization of CalS9 in the biosynthesis of UDP-xylose and the production of xylosyl-attached hybrid compound | Q45375180 | ||
The molecular architecture of galactose mutarotase/UDP-galactose 4-epimerase from Saccharomyces cerevisiae | Q46408194 | ||
Dismutase activity of ADP-L-glycero-D-manno-heptose 6-epimerase: evidence for a direct oxidation/reduction mechanism | Q46431933 | ||
Structural analysis of a set of proteins resulting from a bacterial genomics project. | Q46445101 | ||
Genetically engineered biosynthesis of macrolide derivatives including 4-amino-4,6-dideoxy-L-glucose from Streptomyces venezuelae YJ003-OTBP3. | Q46779416 | ||
Differential role of NADP+ and NADPH in the activity and structure of GDP-D-mannose 4,6-dehydratase from two chlorella viruses. | Q46921021 | ||
Insights into the Branched-Chain Formation of Mycarose: Methylation Catalyzed by an (S)-Adenosylmethionine-Dependent Methyltransferase We are grateful to Dr. Eugene Seno and the Lilly Research Laboratories for their generous gift of the plasmid pHJL | Q48370425 | ||
Mechanistic implications of Escherichia coli galactokinase structure-based engineering. | Q51651257 | ||
Reaction of aspartate aminotransferase with L-erythro-3-hydroxyaspartate: involvement of Tyr70 in stabilization of the catalytic intermediates. | Q52335636 | ||
A rapid screen of active site mutants in glycinamide ribonucleotide transformylase. | Q54585483 | ||
Characterization of a Cys115 to Asp substitution in the Escherichia coli cell wall biosynthetic enzyme UDP-GlcNAc enolpyruvyl transferase (MurA) that confers resistance to inactivation by the antibiotic fosfomycin. | Q54590227 | ||
Variation on a Theme of SDR | Q57278413 | ||
Characterisation of Streptomyces spheroides NovW and revision of its functional assignment to a dTDP-6-deoxy-d-xylo-4-hexulose 3-epimerase | Q57572222 | ||
The 1.6-Å resolution crystal structure of NovW: A 4-keto-6-deoxy sugar epimerase from the novobiocin biosynthetic gene cluster of Streptomyces spheroides | Q57572230 | ||
Lysine 22 in UDP-N-Acetylglucosamine Enolpyruvyl Transferase fromEnterobacter cloacaeIs Crucial for Enzymatic Activity and the Formation of Covalent Adducts with the Substrate Phosphoenolpyruvate and the Antibiotic Fosfomycin† | Q57978316 | ||
Chemical modification of everninomicins | Q70429388 | ||
Uridine diphosphate N-acetyl-D-glucosamine-2-epimerase from rat liver. II. Studies on the mechanism of action | Q70457894 | ||
Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea | Q74266942 | ||
On the mechanism of N-acetylmannosamine formation | Q79252452 | ||
Crystallization and preliminary X-ray crystallographic study of UDP-glucose pyrophosphorylase (UGPase) from Helicobacter pylori | Q80375808 | ||
Insights into the Branched-Chain Formation of Mycarose: Methylation Catalyzed by an (S)-Adenosylmethionine-Dependent Methyltransferase | Q88522050 | ||
Diversifying vancomycin via chemoenzymatic strategies. | Q34409603 | ||
Structures and mechanisms of glycosyltransferases | Q34436062 | ||
Epimerases: structure, function and mechanism | Q34437812 | ||
Functional characterization of dehydratase/aminotransferase pairs from Helicobacter and Campylobacter: enzymes distinguishing the pseudaminic acid and bacillosamine biosynthetic pathways. | Q34467309 | ||
Structural and functional characterization of PseC, an aminotransferase involved in the biosynthesis of pseudaminic acid, an essential flagellar modification in Helicobacter pylori | Q34485821 | ||
Structure, evolution and action of vitamin B6-dependent enzymes | Q34488807 | ||
Structural studies of FlaA1 from Helicobacter pylori reveal the mechanism for inverting 4,6-dehydratase activity | Q34519878 | ||
Crystal structure of TDP-fucosamine acetyltransferase (WecD) from Escherichia coli, an enzyme required for enterobacterial common antigen synthesis | Q34549307 | ||
Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus. | Q34551703 | ||
The molecular structure of UDP-galactose 4-epimerase from Escherichia coli determined at 2.5 A resolution | Q34556266 | ||
Stereospecificity for the hydrogen transfer of pyridoxal enzyme reactions | Q34587643 | ||
Unusual sugar biosynthesis and natural product glycodiversification | Q34623021 | ||
Biosynthetic enzymes of unusual microbial sugars | Q34626027 | ||
Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution | Q34683354 | ||
Mechanistic aspects of enzymatic carbohydrate epimerization | Q34757304 | ||
The impact of enzyme engineering upon natural product glycodiversification | Q34803952 | ||
Mechanisms and structures of vitamin B(6)-dependent enzymes involved in deoxy sugar biosynthesis | Q35046495 | ||
A structural perspective on the enzymes that convert dTDP-d-glucose into dTDP-l-rhamnose | Q35139330 | ||
Natural product glycorandomization. | Q35758002 | ||
Nucleophilic participation of reduced flavin coenzyme in mechanism of UDP-galactopyranose mutase | Q35762957 | ||
Bioactive carbohydrates and recently discovered analogues as chemotherapeutics | Q35768540 | ||
The role of natural product chemistry in drug discovery | Q35994110 | ||
CDP-6-deoxy-delta 3,4-glucoseen reductase from Yersinia pseudotuberculosis: enzyme purification and characterization of the cloned gene | Q36104792 | ||
Glycosyltransferases: managers of small molecules | Q36110231 | ||
Enzymatic tools for engineering natural product glycosylation. | Q36468505 | ||
Inferring the chemical mechanism from structures of enzymes | Q36579441 | ||
Engineering the glycosylation of natural products in actinomycetes | Q36782462 | ||
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars | Q36835457 | ||
Increasing carbohydrate diversity via amine oxidation: aminosugar, hydroxyaminosugar, nitrososugar, and nitrosugar biosynthesis in bacteria | Q36839243 | ||
Carbohydrates in therapeutics | Q36881558 | ||
Discovery and molecular engineering of sugar-containing natural product biosynthetic pathways in actinomycetes. | Q37048281 | ||
Recent knowledge and innovations related to hexofuranosides: structure, synthesis and applications. | Q37148970 | ||
Glycosyltransferases, important tools for drug design | Q37161024 | ||
Characterization of CalE10, the N-oxidase involved in calicheamicin hydroxyaminosugar formation | Q37247384 | ||
??? | Q27748883 | ||
Galactose metabolism in yeast-structure and regulation of the leloir pathway enzymes and the genes encoding them | Q37263636 | ||
Structure and mutagenic conversion of E1 dehydrase: at the crossroads of dehydration, amino transfer, and epimerization | Q37436403 | ||
Investigation of binding of UDP-Galf and UDP-[3-F]Galf to UDP-galactopyranose mutase by STD-NMR spectroscopy, molecular dynamics, and CORCEMA-ST calculations | Q37457660 | ||
A bacterial glycosyltransferase gene toolbox: generation and applications | Q37533001 | ||
Chemistry and biology of galactofuranose-containing polysaccharides | Q37547089 | ||
Structure, mechanism and engineering of plant natural product glycosyltransferases | Q37606691 | ||
Glycosyltransferases and their Assays | Q37776670 | ||
Dynamics of glucosamine-6-phosphate synthase catalysis | Q37779930 | ||
Glycosyltransferases as biocatalysts | Q37844959 | ||
Evidence that the fosfomycin target Cys115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product release | Q37866109 | ||
UDP-N-acetylglucosamine enolpyruvyl transferase as a potential target for antibacterial chemotherapy: recent developments | Q37913126 | ||
Discovery and design of carbohydrate-based therapeutics | Q38029137 | ||
Site-directed mutagenesis of UDP-galactopyranose mutase reveals a critical role for the active-site, conserved arginine residues | Q38301618 | ||
Enhancing the latent nucleotide triphosphate flexibility of the glucose-1-phosphate thymidylyltransferase RmlA. | Q38302744 | ||
Cell wall core galactofuran synthesis is essential for growth of mycobacteria | Q39503992 | ||
Structure of CDP-D-glucose 4,6-dehydratase from Salmonella typhi complexed with CDP-D-xylose | Q41458900 | ||
Identification of an unusual [2Fe-2S]-binding motif in the CDP-6-deoxy-D-glycero-l-threo-4-hexulose-3-dehydrase from Yersinia pseudotuberculosis: implication for C-3 deoxygenation in the biosynthesis of 3,6-dideoxyhexoses | Q41460846 | ||
Crystal structure at 1.8 A resolution of CDP-D-glucose 4,6-dehydratase from Yersinia pseudotuberculosis | Q41463453 | ||
The biosynthesis of GDP-L-colitose: C-3 deoxygenation is catalyzed by a unique coenzyme B6-dependent enzyme | Q41467641 | ||
The role of carbohydrates in biologically active natural products | Q41468708 | ||
Kinetic characterization of an organic radical in the ascarylose biosynthetic pathway | Q41489921 | ||
Cofactor characterization and mechanistic studies of CDP-6-deoxy-delta 3,4-glucoseen reductase: exploration into a novel enzymatic C-O bond cleavage event | Q41501451 | ||
The structure of GDP-4-keto-6-deoxy-D-mannose-3-dehydratase: a unique coenzyme B6-dependent enzyme | Q41842380 | ||
Crystal structures of Mycobacteria tuberculosis and Klebsiella pneumoniae UDP-galactopyranose mutase in the oxidised state and Klebsiella pneumoniae UDP-galactopyranose mutase in the (active) reduced state | Q41878559 | ||
A unifying nitrososynthase involved in nitrosugar biosynthesis | Q41960421 | ||
Synthesis and analysis of substrate analogues for UDP-galactopyranose mutase: implication for an oxocarbenium ion intermediate in the catalytic mechanism | Q42390505 | ||
Evolutionarily conserved regions and hydrophobic contacts at the superfamily level: The case of the fold-type I, pyridoxal-5'-phosphate-dependent enzymes | Q42638678 | ||
Biosynthesis of rubradirin as an ansamycin antibiotic from Streptomyces achromogenes var. rubradiris NRRL3061. | Q42639702 | ||
Kinetic and structural analysis of alpha-D-Glucose-1-phosphate cytidylyltransferase from Salmonella typhi | Q42644312 | ||
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | glycosylation | Q898365 |
natural product | Q901227 | ||
structural biology | Q908902 | ||
drug discovery | Q1418791 | ||
organic chemistry | Q11351 | ||
P304 | page(s) | 1201-1237 | |
P577 | publication date | 2012-06-12 | |
P1433 | published in | Natural Product Reports | Q2376904 |
P1476 | title | The structural biology of enzymes involved in natural product glycosylation | |
P478 | volume | 29 |
Q64072654 | A Parsimonious Mechanism of Sugar Dehydration by Human GDP-Mannose-4,6-dehydratase |
Q36029831 | A comprehensive review of glycosylated bacterial natural products. |
Q33824731 | A general NMR-based strategy for the in situ characterization of sugar-nucleotide-dependent biosynthetic pathways |
Q50447267 | A new pre-column derivatization for valienamine and beta-valienamine using o-phthalaldehyde to determine the epimeric purity by HPLC and application of this method to monitor enzymatic catalyzed synthesis of beta-valienamine. |
Q41885331 | A one-pot enzymatic approach to the O-fluoroglucoside of N-methylanthranilate |
Q42196781 | Allosteric Control of Substrate Specificity of the Escherichia coli ADP-Glucose Pyrophosphorylase. |
Q36754853 | Aqueous Glycosylation of Unprotected Sucrose Employing Glycosyl Fluorides in the Presence of Calcium Ion and Trimethylamine. |
Q28081578 | Architecture of the polyketide synthase module: surprises from electron cryo-microscopy |
Q38216655 | Bioactive oligosaccharide natural products |
Q59124355 | Biosynthesis and Biological Activity of Carbasugars |
Q48131343 | Biosynthetic 4,6-dehydratase gene deletion: isolation of a glucosylated jadomycin natural product provides insight into the substrate specificity of glycosyltransferase JadS. |
Q36835716 | Broadening the scope of glycosyltransferase-catalyzed sugar nucleotide synthesis |
Q36137644 | Characterization of Early Enzymes Involved in TDP-Aminodideoxypentose Biosynthesis en Route to Indolocarbazole AT2433. |
Q91643308 | Cryo-EM structure of L-fucokinase/GDP-fucose pyrophosphorylase (FKP) in Bacteroides fragilis |
Q31811695 | Crystal Structure of the N-Acetylmuramic Acid α-1-Phosphate (MurNAc-α1-P) Uridylyltransferase MurU, a Minimal Sugar Nucleotidyltransferase and Potential Drug Target Enzyme in Gram-negative Pathogens |
Q48203787 | Crystal structure of a UDP-GlcNAc epimerase for surface polysaccharide biosynthesis in Acinetobacter baumannii |
Q64953997 | Discovery of an RmlC/D fusion protein in the microalga Prymnesium parvum and its implications for NDP-β-l-rhamnose biosynthesis in microalgae. |
Q44927649 | Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation. |
Q38429805 | Enhanced production of nargenicin A(1) and generation of novel glycosylated derivatives. |
Q58772177 | Enzymatic Synthesis of the C-Glycosidic Moiety of Nogalamycin R |
Q34702005 | Enzymatic methylation and structure-activity-relationship studies on polycarcin V, a gilvocarcin-type antitumor agent |
Q33737744 | Enzymatic synthesis of epothilone A glycosides |
Q30993753 | Enzymatic synthesis of novel isobavachalcone glucosides via a UDP-glycosyltransferase |
Q37340715 | Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules |
Q34548172 | Identification of Neuroprotective Spoxazomicin and Oxachelin Glycosides via Chemoenzymatic Glycosyl-Scanning |
Q54309024 | Kinetic evaluation of glucose 1-phosphate analogues with a thymidylyltransferase using a continuous coupled enzyme assay. |
Q36599498 | Loop dynamics of thymidine diphosphate-rhamnose 3'-O-methyltransferase (CalS11), an enzyme in calicheamicin biosynthesis |
Q50676392 | Metabolomic Analysis of Mice Exposed to Gamma Radiation Reveals a Systemic Understanding of Total-Body Exposure. |
Q33951389 | Neoglycosylation and neoglycorandomization: Enabling tools for the discovery of novel glycosylated bioactive probes and early stage leads |
Q54292404 | Polyphosphate-containing bisubstrate analogues as inhibitors of a bacterial cell wall thymidylyltransferase. |
Q38272215 | Potential applications of glucosyltransferases in terpene glucoside production: impacts on the use of aroma and fragrance |
Q36074427 | Structural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases |
Q36283579 | Structural Characterization of CalS8, a TDP-α-D-Glucose Dehydrogenase Involved in Calicheamicin Aminodideoxypentose Biosynthesis |
Q37419993 | Structural and functional characterization of CalS11, a TDP-rhamnose 3'-O-methyltransferase involved in calicheamicin biosynthesis |
Q35612402 | Structural basis of substrate specificity and regiochemistry in the MycF/TylF family of sugar O-methyltransferases. |
Q36060114 | Structural characterization of AtmS13, a putative sugar aminotransferase involved in indolocarbazole AT2433 aminopentose biosynthesis |
Q41865226 | Structural characterization of O- and C-glycosylating variants of the landomycin glycosyltransferase LanGT2 |
Q38428716 | Structural modification of herboxidiene by substrate-flexible cytochrome P450 and glycosyltransferase. |
Q37270510 | Synthesis and antibacterial activity of doxycycline neoglycosides. |
Q34428173 | The evolution of enzyme function in the isomerases |
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