| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1016/S0959-440X(98)80096-1 |
| P8608 | Fatcat ID | release_7tz3tdb6jzcpjdva3jbplyqqre |
| P698 | PubMed publication ID | 9914259 |
| P2093 | author name string | Jansonius JN | |
| P2860 | cites work | The crystal structure of human cytosolic serine hydroxymethyltransferase: a target for cancer chemotherapy | Q22003869 |
| Crystal structure of human recombinant ornithine aminotransferase | Q24318752 | ||
| Three-dimensional structure of a pyridoxal-phosphate-dependent enzyme, mitochondrial aspartate aminotransferase | Q24615207 | ||
| Modeling of the spatial structure of eukaryotic ornithine decarboxylases | Q24675092 | ||
| Crystallographic structure of a PLP-dependent ornithine decarboxylase from Lactobacillus 30a to 3.0 A resolution | Q27729607 | ||
| Crystal structure of a D-amino acid aminotransferase: how the protein controls stereoselectivity | Q27729786 | ||
| The allosteric ligand site in the Vmax-type cooperative enzyme phosphoglycerate dehydrogenase | Q27730185 | ||
| X-ray crystallographic study of pyridoxal 5'-phosphate-type aspartate aminotransferases from Escherichia coli in open and closed form | Q27730297 | ||
| Crystal structure of the closed form of chicken cytosolic aspartate aminotransferase at 1.9 A resolution | Q27730431 | ||
| Three-dimensional structure of tyrosine phenol-lyase | Q27730686 | ||
| An alkali metal ion size-dependent switch in the active site structure of dialkylglycine decarboxylase | Q27730740 | ||
| Dialkylglycine decarboxylase structure: bifunctional active site and alkali metal sites | Q27731968 | ||
| Exchange of K+ or Cs+ for Na+ induces local and long-range changes in the three-dimensional structure of the tryptophan synthase alpha2beta2 complex | Q27732858 | ||
| Crystal structure of the pyridoxal-5'-phosphate dependent cystathionine beta-lyase from Escherichia coli at 1.83 A | Q27733453 | ||
| Determination of the structure of alanine racemase from Bacillus stearothermophilus at 1.9-A resolution | Q27734979 | ||
| Crystal structure of glutamate-1-semialdehyde aminomutase: an alpha2-dimeric vitamin B6-dependent enzyme with asymmetry in structure and active site reactivity | Q27737074 | ||
| Three-dimensional structure of Escherichia coli branched-chain amino acid aminotransferase at 2.5 A resolution | Q27738062 | ||
| The crystal structure of Citrobacter freundii tyrosine phenol-lyase complexed with 3-(4'-hydroxyphenyl)propionic acid, together with site-directed mutagenesis and kinetic analysis, demonstrates that arginine 381 is required for substrate specificity | Q27738684 | ||
| Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes | Q27739855 | ||
| Human ornithine aminotransferase complexed with L-canaline and gabaculine: structural basis for substrate recognition | Q27744324 | ||
| Slow-binding inhibition of Escherichia coli cystathionine beta-lyase by L-aminoethoxyvinylglycine: a kinetic and X-ray study | Q27747982 | ||
| Cryo-crystallography of a true substrate, indole-3-glycerol phosphate, bound to a mutant (alphaD60N) tryptophan synthase alpha2beta2 complex reveals the correct orientation of active site alphaGlu49 | Q27749040 | ||
| Crystallographic study of steps along the reaction pathway of D-amino acid aminotransferase | Q27749055 | ||
| Loop closure and intersubunit communication in tryptophan synthase | Q27749110 | ||
| Crystal structure of tryptophanase | Q27749198 | ||
| Structure and control of pyridoxal phosphate dependent allosteric threonine deaminase | Q27749646 | ||
| Crystal structures of Paracoccus denitrificans aromatic amino acid aminotransferase: a substrate recognition site constructed by rearrangement of hydrogen bond network | Q27764717 | ||
| Reaction of alanine racemase with 1-aminoethylphosphonic acid forms a stable external aldimine | Q27764847 | ||
| Three-dimensional structure of O-acetylserine sulfhydrylase from Salmonella typhimurium | Q27765637 | ||
| Pyridoxal phosphate-dependent enzymes | Q34310491 | ||
| Domain closure in mitochondrial aspartate aminotransferase | Q34330037 | ||
| Evolutionary relationships among pyridoxal-5'-phosphate-dependent enzymes. Regio-specific alpha, beta and gamma families | Q34336063 | ||
| Multiple evolutionary origin of pyridoxal-5'-phosphate-dependent amino acid decarboxylases | Q34341052 | ||
| Pyridoxal enzymes: mechanistic diversity and uniformity | Q34387378 | ||
| X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase | Q34423853 | ||
| Aminotransferases: demonstration of homology and division into evolutionary subgroups. | Q34731352 | ||
| Crystal structure of Saccharomyces cerevisiae cytosolic aspartate aminotransferase | Q36281057 | ||
| Conformation and reaction specificity in pyridoxal phosphate enzymes | Q36457621 | ||
| DL-canaline and 5-fluoromethylornithine. Comparison of two inactivators of ornithine aminotransferase | Q41940646 | ||
| Structural motifs for pyridoxal‐5′‐phosphate binding in decarboxylases: An analysis based on the crystal structure of the Lactobacillus 30a ornithine decarboxylase | Q42121460 | ||
| Importance of conserved and variable C-terminal residues for the activity and thermal stability of the beta subunit of tryptophan synthase | Q42651699 | ||
| The active site of Sulfolobus solfataricus aspartate aminotransferase. | Q43017366 | ||
| Crystal structure analysis of omega-amino acid:pyruvate aminotransferase with a newly developed Weissenberg camera and an imaging plate using synchrotron radiation | Q44391802 | ||
| The Streptomyces tendae Tü901 L-lysine 2-aminotransferase catalyzes the initial reaction in nikkomycin D biosynthesis | Q47861741 | ||
| Evolutionary analysis of aspartate aminotransferases | Q58219133 | ||
| Evolutionary relationships among aminotransferases. Tyrosine aminotransferase, histidinol-phosphate aminotransferase, and aspartate aminotransferase are homologous proteins | Q69377317 | ||
| Structural and mechanistic analysis of two refined crystal structures of the pyridoxal phosphate-dependent enzyme dialkylglycine decarboxylase | Q72355199 | ||
| Homology of 1-aminocyclopropane-1-carboxylate synthase, 8-amino-7-oxononanoate synthase, 2-amino-6-caprolactam racemase, 2,2-dialkylglycine decarboxylase, glutamate-1-semialdehyde 2,1-aminomutase and isopenicillin-N-epimerase with aminotransferases | Q72733043 | ||
| Mutations in the contact region between the alpha and beta subunits of tryptophan synthase alter subunit interaction and intersubunit communication | Q74252453 | ||
| Mutation of arginine 98, which serves as a substrate-recognition site of D-amino acid aminotransferase, can be partly compensated for by mutation of tyrosine 88 to an arginyl residue | Q74302965 | ||
| P433 | issue | 6 | |
| P921 | main subject | vitamin | Q34956 |
| vitamin B | Q183206 | ||
| vitamin B6 | Q205130 | ||
| P304 | page(s) | 759-769 | |
| P577 | publication date | 1998-12-01 | |
| P1433 | published in | Current Opinion in Structural Biology | Q15758416 |
| P1476 | title | Structure, evolution and action of vitamin B6-dependent enzymes | |
| P478 | volume | 8 |
| Q92183055 | 5-Aminolevulinate synthase catalysis: The catcher in heme biosynthesis |
| Q27649009 | A Structural Study of GDP-4-Keto-6-Deoxy- d -Mannose-3-Dehydratase: Caught in the Act of Geminal Diamine Formation † , ‡ |
| Q64263011 | A Survey of Pyridoxal 5'-Phosphate-Dependent Proteins in the Gram-Positive Model Bacterium |
| Q47885448 | A eukaryotic alanine racemase gene involved in cyclic peptide biosynthesis |
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| Q27652172 | Accommodation of GDP-linked sugars in the active site of GDP-perosamine synthase |
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| Q48382744 | Amino acid sequences and hapten binding of catalytic and noncatalytic antibodies against N(alpha)-(5'-phosphopyridoxyl)-L-lysine |
| Q42944871 | An insight into the sequential, structural and phylogenetic properties of banana 1-aminocyclopropane-1-carboxylate synthase 1 and study of its interaction with pyridoxal-5′-phosphate and aminoethoxyvinylglycine |
| Q37624340 | Aspartate aminotransferase: an old dog teaches new tricks |
| Q44624225 | Avoiding the Road Less Traveled: How the Topology of Enzyme−Substrate Complexes Can Dictate Product Selection |
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| Q24645615 | Biochemical and structural properties of mouse kynurenine aminotransferase III |
| Q34044443 | Biogenesis of iron-sulfur proteins in eukaryotes: a novel task of mitochondria that is inherited from bacteria |
| Q46110576 | Biophysical characterization of Entamoeba histolytica phosphoserine aminotransferase (EhPSAT): role of cofactor and domains in stability and subunit assembly |
| Q41155643 | Biosynthesis of Epimers C2 and C2a in the Gentamicin C Complex |
| Q24805274 | Branched-chain amino acid aminotransferase and methionine formation in Mycobacterium tuberculosis |
| Q38126497 | Catalysis in Enzymatic Decarboxylations: Comparison of Selected Cofactor-dependent and Cofactor-independent Examples |
| Q43021274 | Cloning and characterization of a novel fold-type I branched-chain amino acid aminotransferase from the hyperthermophilic archaeon Thermococcus sp. CKU-1. |
| Q36606141 | Clonostachys rosea demethiolase STR3 controls the conversion of methionine into methanethiol |
| Q73712694 | Comparison of folding rates of homologous prokaryotic and eukaryotic proteins |
| Q30044033 | Completing the folate biosynthesis pathway in Plasmodium falciparum: p-aminobenzoate is produced by a highly divergent promiscuous aminodeoxychorismate lyase |
| Q92759002 | Computational classification of MocR transcriptional regulators into subgroups as a support for experimental and functional characterization |
| Q89626651 | Conformational flexibility within the small domain of human serine racemase |
| Q57189215 | Connecting Unexplored Protein Crystal Structures to Enzymatic Function |
| Q37888147 | Controlling reaction specificity in pyridoxal phosphate enzymes |
| Q27659151 | Crystal Structure and Substrate Specificity of Drosophila 3,4-Dihydroxyphenylalanine Decarboxylase |
| Q27678552 | Crystal Structure of Escherichia coli Diaminopropionate Ammonia-lyase Reveals Mechanism of Enzyme Activation and Catalysis |
| Q27681585 | Crystal Structure of an (R)-Selective ω-Transaminase from Aspergillus terreus |
| Q27641829 | Crystal structure and functional analysis of Escherichia coli glutamate decarboxylase |
| Q34336613 | Crystal structure and reactivity of YbdL from Escherichia coli identify a methionine aminotransferase function |
| Q24653746 | Crystal structure of Homo sapiens kynureninase |
| Q27625168 | Crystal structure of cystalysin from Treponema denticola: a pyridoxal 5'-phosphate-dependent protein acting as a haemolytic enzyme |
| Q24303814 | Crystal structure of human kynurenine aminotransferase I |
| Q27649207 | Crystal structure of human kynurenine aminotransferase II |
| Q27649208 | Crystal structure of human kynurenine aminotransferase II, a drug target for the treatment of schizophrenia |
| Q27648976 | Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099 |
| Q34595893 | Crystal structure of the Anopheles gambiae 3-hydroxykynurenine transaminase |
| Q27622181 | Crystal structure of the cystine C-S lyase from Synechocystis: stabilization of cysteine persulfide for FeS cluster biosynthesis |
| Q27683595 | Crystal structure of the ω-aminotransferase from Paracoccus denitrificans and its phylogenetic relationship with other class III aminotransferases that have biotechnological potential |
| Q43031569 | Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase |
| Q27643084 | Crystal structures of glutamine:phenylpyruvate aminotransferase from Thermus thermophilus HB8: induced fit and substrate recognition |
| Q27670421 | Crystal structures of open and closed forms of d-serine deaminase from Salmonella typhimurium - implications on substrate specificity and catalysis |
| Q27641948 | Crystal structures of threonine synthase from Thermus thermophilus HB8: conformational change, substrate recognition, and mechanism |
| Q27689937 | Crystallographic characterization of the (R)-selective amine transaminase from Aspergillus fumigatus |
| Q58747739 | Dimerization misalignment in human glutamate-oxaloacetate transaminase variants is the primary factor for PLP release |
| Q44348857 | Effect of P2 receptor blockade with pyridoxine on sympathetic response to exercise pressor reflex in humans |
| Q50503615 | Effect of dietary lysine restriction and arginine supplementation in two patients with pyridoxine-dependent epilepsy. |
| Q34377792 | Enzyme adaptation to alkaline pH: atomic resolution (1.08 A) structure of phosphoserine aminotransferase from Bacillus alcalophilus. |
| Q34008808 | Enzyme replacement therapy for murine hypophosphatasia |
| Q42638678 | Evolutionarily conserved regions and hydrophobic contacts at the superfamily level: The case of the fold-type I, pyridoxal-5'-phosphate-dependent enzymes |
| Q44438001 | Exaggerated exercise pressor reflex in adults with moderately elevated systolic blood pressure: role of purinergic receptors |
| Q35103535 | FT-IR study of pyridoxamine 5' phosphate |
| Q27704011 | First structure of archaeal branched-chain amino acid aminotransferase from Thermoproteus uzoniensis specific for L-amino acids and R-amines |
| Q28212888 | From cofactor to enzymes. The molecular evolution of pyridoxal-5'-phosphate-dependent enzymes |
| Q34254917 | Functional evolution of PLP-dependent enzymes based on active-site structural similarities |
| Q27644229 | GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop |
| Q44568867 | Genome-based analysis of biosynthetic aminotransferase genes of Corynebacterium glutamicum |
| Q53408140 | Human kynurenine aminotransferase II - reactivity with substrates and inhibitors |
| Q42008004 | Hypophosphatasia - pathophysiology and treatment. |
| Q27696187 | Identification and characterization of a methionine γ-lyase in the calicheamicin biosynthetic cluster of Micromonospora echinospora |
| Q48102825 | Identification of novel thermostable taurine-pyruvate transaminase from Geobacillus thermodenitrificans for chiral amine synthesis. |
| Q47374823 | Identification of pyridoxal phosphate modified proteins using mass spectrometry. |
| Q58696652 | Improved l-Leucine Production in by Optimizing the Aminotransferases |
| Q52566926 | Improvement of kynurenine aminotransferase-II inhibitors guided by mimicking sulfate esters. |
| Q47106343 | Inhibition of human kynurenine aminotransferase isozymes by estrogen and its derivatives |
| Q46049566 | Interconversion of a pair of active-site residues in Escherichia coli cystathionine gamma-synthase, E. coli cystathionine beta-lyase, and Saccharomyces cerevisiae cystathionine gamma-lyase and development of tools for the investigation of their mech |
| Q46823953 | Kinetic characterization of the human O-phosphoethanolamine phospho-lyase reveals unconventional features of this specialized pyridoxal phosphate-dependent lyase. |
| Q26744492 | Kynurenine Aminotransferase Isozyme Inhibitors: A Review |
| Q37287051 | Large Sequence Diversity within the Biosynthesis Locus and Common Biochemical Features of Campylobacter coli Lipooligosaccharides |
| Q28584255 | Local changes in the catalytic site of mammalian histidine decarboxylase can affect its global conformation and stability |
| Q42152892 | Mapping of catalytically important residues in the rat L-histidine decarboxylase enzyme using bioinformatic and site-directed mutagenesis approaches. |
| Q35046495 | Mechanisms and structures of vitamin B(6)-dependent enzymes involved in deoxy sugar biosynthesis |
| Q39743843 | Methionine regeneration and aminotransferases in Bacillus subtilis, Bacillus cereus, and Bacillus anthracis. |
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| Q27657441 | Molecular Basis of Reduced Pyridoxine 5′-Phosphate Oxidase Catalytic Activity in Neonatal Epileptic Encephalopathy Disorder |
| Q27684034 | Molecular characterization of novel pyridoxal-5′-phosphate-dependent enzymes from the human microbiome |
| Q48065730 | Molecular dynamics simulations of apo, holo, and inactivator bound GABA-at reveal the role of active site residues in PLP dependent enzymes |
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| Q42254173 | Overexpression, purification and crystallization of lysine epsilon-aminotransferase (Rv3290c) from Mycobacterium tuberculosis H37Rv. |
| Q44814658 | Oxidation and transamination of the 3"-position of UDP-N-acetylglucosamine by enzymes from Acidithiobacillus ferrooxidans. Role in the formation of lipid a molecules with four amide-linked acyl chains |
| Q35353935 | PLP-dependent H(2)S biogenesis |
| Q44704345 | Pharmacorefractory status epilepticus due to low vitamin B6 levels during pregnancy |
| Q45598697 | PvdN Enzyme Catalyzes a Periplasmic Pyoverdine Modification |
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| Q33703675 | Rational assignment of key motifs for function guides in silico enzyme identification |
| Q27641738 | Reaction intermediate structures of 1-aminocyclopropane-1-carboxylate deaminase: insight into PLP-dependent cyclopropane ring-opening reaction |
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| Q56880117 | Recurrent Emergence of Catalytically Inactive Ornithine Decarboxylase Homologous Forms That Likely Have Regulatory Function |
| Q36557536 | Regulation of L-histidine decarboxylase and its role in carcinogenesis. |
| Q53401736 | Role of active-site residues Tyr55 and Tyr114 in catalysis and substrate specificity of Corynebacterium diphtheriae C-S lyase. |
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| Q39367259 | Strain relief at the active site of phosphoserine aminotransferase induced by radiation damage |
| Q27663161 | Structural Analysis of WbpE from Pseudomonas aeruginosa PAO1: A Nucleotide Sugar Aminotransferase Involved in O-Antigen Assembly, |
| Q27681447 | Structural Basis for Substrate Specificity in ArnB. A Key Enzyme in the Polymyxin Resistance Pathway of Gram-Negative Bacteria |
| Q27679004 | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase |
| Q27684595 | Structural and biochemical analyses of alanine racemase from the multidrug-resistantClostridium difficilestrain 630 |
| Q27696179 | Structural and biochemical characterization of the dual substrate recognition of the (R)-selective amine transaminase from Aspergillus fumigatus |
| Q52316858 | Structural and functional studies of Spr1654: an essential aminotransferase in teichoic acid biosynthesis in Streptococcus pneumoniae. |
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| Q27639608 | Structural basis for the inhibition of the biosynthesis of biotin by the antibiotic amiclenomycin |
| Q28115621 | Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin |
| Q24311414 | Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase K |
| Q24633553 | Structural insight into the mechanism of substrate specificity of aedes kynurenine aminotransferase |
| Q27649423 | Structural insights into RNA-dependent eukaryal and archaeal selenocysteine formation |
| Q27656285 | Structural insights into the enzymatic mechanism of serine palmitoyltransferase from Sphingobacterium multivorum |
| Q44790629 | Structural studies of the catalytic reaction pathway of a hyperthermophilic histidinol-phosphate aminotransferase |
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| Q28201105 | Structure and function of branched chain aminotransferases |
| Q27637092 | Structure and function of threonine synthase from yeast |
| Q37436403 | Structure and mutagenic conversion of E1 dehydrase: at the crossroads of dehydration, amino transfer, and epimerization |
| Q42614811 | Structure modelling and site-directed mutagenesis of the rat aromatic L-amino acid pyridoxal 5'-phosphate-dependent decarboxylase: a functional study |
| Q42411820 | Structure of Citrobacter freundii L-methionine gamma-lyase. |
| Q42651682 | Structure of P-protein of the glycine cleavage system: implications for nonketotic hyperglycinemia |
| Q27618764 | Structure of mammalian ornithine decarboxylase at 1.6 A resolution: stereochemical implications of PLP-dependent amino acid decarboxylases |
| Q54475918 | Structure of methionine γ-lyase from Clostridium sporogenes. |
| Q28545177 | Structure of putrescine aminotransferase from Escherichia coli provides insights into the substrate specificity among class III aminotransferases |
| Q40749076 | Structure of the PLP-Form of the Human Kynurenine Aminotransferase II in a Novel Spacegroup at 1.83 Å Resolution |
| Q27657768 | Structure, expression, and function of kynurenine aminotransferases in human and rodent brains |
| Q84855283 | Studies on molecular structure and tautomerism of a vitamin B6 analog with density functional theory |
| Q34698692 | Substituent effects on electrophilic catalysis by the carbonyl group: anatomy of the rate acceleration for PLP-catalyzed deprotonation of glycine. |
| Q33508885 | Substituent effects on the thermodynamic stability of imines formed from glycine and aromatic aldehydes: implications for the catalytic activity of pyridoxal-5'-phosphate. |
| Q61814297 | The Alkaline Phosphatase (ALPL) Locus Is Associated with B6 Vitamer Levels in CSF and Plasma |
| Q33499094 | The B6 database: a tool for the description and classification of vitamin B6-dependent enzymatic activities and of the corresponding protein families |
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| Q33836870 | The manifold of vitamin B6 dependent enzymes. |
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| Q52667531 | The three-dimensional structure of NeoB: An aminotransferase involved in the biosynthesis of neomycin. |
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