scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1016/S0099-9598(03)60001-5 |
P698 | PubMed publication ID | 14593855 |
P50 | author | Jaap Verweij | Q98683725 |
Alex Sparreboom | Q71780219 | ||
P2093 | author name string | Otto Soepenberg | |
P2860 | cites work | Cancer Research | Q326097 |
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Phase II trial of 9-aminocamptothecin as a 72-h infusion in cutaneous T-cell lymphoma | Q33339001 | ||
A phase I and pharmacologic study of 9-aminocamptothecin administered as a 120-h infusion weekly to adult cancer patients | Q33339212 | ||
Phase I-II study of irinotecan combined with mitomycin-C in patients with advanced gastric cancer | Q33341045 | ||
Randomized phase II study of irinotecan plus mitomycin C vs. oxaliplatin plus mitomycin C in patients with advanced fluoropyrimidine/leucovorin-pretreated colorectal cancer | Q33341120 | ||
Weekly chemotherapy with carboplatin, docetaxel and irinotecan in advanced non-small-cell-lung cancer: a phase II study | Q33342696 | ||
Multicentre phase II and pharmacokinetic study of RFS2000 (9-nitro-camptothecin) administered orally 5 days a week in patients with glioblastoma multiforme | Q33343042 | ||
Phase I study of weekly CPT-11 (irinotecan)/docetaxel in patients with advanced solid tumors | Q33343374 | ||
Dose-escalation study of weekly irinotecan and daily carboplatin with concurrent thoracic radiotherapy for unresectable stage III non-small cell lung cancer | Q33343743 | ||
Phase II study of weekly irinotecan and carboplatin for refractory or relapsed small-cell lung cancer | Q33344308 | ||
Phase I and pharmacologic study of topotecan: a novel topoisomerase I inhibitor | Q33350574 | ||
Phase I and pharmacologic study of irinotecan and etoposide with recombinant human granulocyte colony-stimulating factor support for advanced lung cancer | Q33487960 | ||
Phase I clinical and pharmacokinetic study of topotecan administered by a 24-hour continuous infusion | Q33488685 | ||
Phase I Clinical and Pharmacology Study of Topotecan Given Daily for 5 Consecutive Days to Patients With Advanced Solid Tumors, With Attempt at Dose Intensification Using Recombinant Granulocyte Colony-Stimulating Factor | Q33489257 | ||
Phase I trial of low-dose continuous topotecan infusion in patients with cancer: an active and well-tolerated regimen | Q33492322 | ||
Phase I and pharmacological study of the new topoisomerase I inhibitor GI147211, using a daily x 5 intravenous administration | Q33495553 | ||
Phase II study of topotecan in patients with advanced non-small-cell lung cancer previously untreated with chemotherapy | Q33495774 | ||
Pharmacokinetics and pharmacodynamics of topotecan given on a daily-times-five schedule in phase II clinical trials using a limited-sampling procedure | Q33495882 | ||
Phase II study of topotecan in patients with recurrent malignant glioma. National Clinical Institute of Canada Clinical Trials Group | Q33496743 | ||
A phase I study of irinotecan and infusional cisplatin for advanced non-small-cell lung cancer | Q33498400 | ||
Phase I-II study of irinotecan hydrochloride combined with cisplatin in patients with advanced gastric cancer | Q33498653 | ||
Phase I and pharmacologic study of oral topotecan administered twice daily for 21 days to adult patients with solid tumors | Q33498657 | ||
The bioavailability of oral GI147211 (GG211), a new topoisomerase I inhibitor | Q33500497 | ||
9-Aminocamptothecin by 72-hour continuous intravenous infusion is inactive in the treatment of patients with 5-fluorouracil-refractory colorectal carcinoma. | Q33500679 | ||
Phase II trial to topotecan in hepatocellular carcinoma: a Southwest Oncology Group study | Q33500972 | ||
Evaluation of topotecan in resistant and relapsing multiple myeloma: a Southwest Oncology Group study | Q33501662 | ||
Phase II evaluation of topotecan in patients with advanced colorectal cancer. A Southwest Oncology Group trial (SWOG 9241). | Q33502171 | ||
Phase II and dose-escalation with or without granulocyte colony-stimulating factor study of 9-aminocamptothecin in relapsed and refractory lymphomas | Q33503047 | ||
Phase I trial of 9-aminocamptothecin in children with refractory solid tumors: a Pediatric Oncology Group study | Q33503056 | ||
Combination of irinotecan and etoposide for treatment of refractory or relapsed small-cell lung cancer | Q33503969 | ||
CPT-11 in combination with cisplatin for advanced non-small-cell lung cancer | Q67504713 | ||
Phase I Study of Weekly Intravenous Infusions of CPT-11, a New Derivative of Camptothecin, in the Treatment of Advanced Non-Small-Cell Lung Cancer | Q68252500 | ||
DNA topoisomerase I--targeted chemotherapy of human colon cancer in xenografts | Q69360455 | ||
Localization of the active type I DNA topoisomerase gene on human chromosome 20q11.2-13.1, and two pseudogenes on chromosomes 1q23-24 and 22q11.2-13.1. | Q69362155 | ||
DNA topoisomerases | Q70095180 | ||
Report of the Cancer Therapy Evaluation Program monitoring plan for secondary acute myeloid leukemia following treatment with epipodophyllotoxins | Q70616408 | ||
Topotecan in colorectal cancer: a phase II study of the EORTC early clinical trials group | Q70970931 | ||
Phase I and pharmacologic studies of topotecan in patients with impaired hepatic function | Q71093671 | ||
Phase I and pharmacologic study of 9-aminocamptothecin given by 72-hour infusion in adult cancer patients | Q71121113 | ||
Phase II study of topotecan in patients with extensive-stage small-cell carcinoma of the lung: an Eastern Cooperative Oncology Group Trial | Q71261842 | ||
Phase II study of topotecan in metastatic hormone-refractory prostate cancer | Q71321842 | ||
Phase II and pharmacologic study of topotecan administered as a 21-day continuous infusion to patients with colorectal cancer | Q71572036 | ||
Phase II trial of topotecan in advanced or metastatic adenocarcinoma of the pancreas | Q71574198 | ||
A phase II trial of topotecan in patients with previously untreated pancreatic cancer | Q71579235 | ||
Phase I study of irinotecan and cisplatin with granulocyte colony-stimulating factor support for advanced non-small-cell lung cancer | Q71604258 | ||
Pharmacokinetics and pharmacodynamics of irinotecan during a phase II clinical trial in colorectal cancer. Pharmacology and Molecular Mechanisms Group of the European Organization for Research and Treatment of Cancer | Q71692731 | ||
Phase I and pharmacologic study of topotecan in patients with impaired renal function | Q71861177 | ||
Phase II study of irinotecan and etoposide in patients with metastatic non-small-cell lung cancer | Q71975354 | ||
Phase I study of CPT-11 and etoposide in patients with refractory solid tumors | Q72098386 | ||
Clinical studies of irinotecan alone and in combination with cisplatin | Q72149455 | ||
Antitumor effect of liposome-incorporated camptothecin in human malignant xenografts | Q72252535 | ||
Phase II study of topotecan in metastatic non-small-cell lung cancer | Q72256259 | ||
Topoisomerase I inhibition: a new target or new missiles? | Q72327065 | ||
Pharmacokinetics and pharmacodynamics of topotecan administered daily for 5 days every 3 weeks | Q72368989 | ||
Phase I and pharmacokinetic trial of weekly CPT-11 | Q72576855 | ||
Phase I and pharmacokinetics study of topotecan, a new topoisomerase I inhibitor | Q72609210 | ||
Enzymes that push DNA around | Q73037272 | ||
Comparison of DX-8951f and topotecan effects on tumor colony formation from freshly explanted adult and pediatric human tumor cells | Q73044019 | ||
Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan | Q73088375 | ||
Effects of extended chronic exposures on endogenous and transgenic loci: implications for low-dose extrapolations | Q73102506 | ||
Phase I and pharmacokinetic study of irinotecan administered as a low-dose, continuous intravenous infusion over 14 days in patients with malignant solid tumors | Q73181530 | ||
Dose escalation of CPT-11 in combination with oxaliplatin using an every two weeks schedule: a phase I study in advanced gastrointestinal cancer patients | Q73356010 | ||
Topotecan, a new active drug in the second-line treatment of small-cell lung cancer: a phase II study in patients with refractory and sensitive disease. The European Organization for Research and Treatment of Cancer Early Clinical Studies Group and | Q73368715 | ||
A phase II study of topotecan in patients with recurrent head and neck cancer. Identification of an active new agent | Q73376814 | ||
Phase I study of a weekly infusion of irinotecan hydrochloride (CPT-11) and a 14-day continuous infusion of etoposide in patients with lung cancer: JCOG trial 9408 | Q73392354 | ||
Topotecan versus paclitaxel for the treatment of recurrent epithelial ovarian cancer | Q73443071 | ||
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1-50 | |
P577 | publication date | 2003-01-01 | |
P1433 | published in | The alkaloids. Chemistry and biology | Q26842446 |
P1476 | title | Clinical studies of camptothecin and derivatives | |
P478 | volume | 60 |
Q45220663 | Molecular characterization of two anthranilate synthase alpha subunit genes in Camptotheca acuminata | cites work | P2860 |
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