Isolation and partial characterisation of a Chinese hamster O6-alkylguanine-DNA alkyltransferase cDNA

scientific article published on April 25, 1992

Isolation and partial characterisation of a Chinese hamster O6-alkylguanine-DNA alkyltransferase cDNA is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NAR/20.8.1891
P953full work available at URLhttps://europepmc.org/articles/PMC312303
https://europepmc.org/articles/PMC312303?pdf=render
P932PMC publication ID312303
P698PubMed publication ID1579490
P5875ResearchGate publication ID21575220

P50authorPhilip M PotterQ41526409
P2093author name stringA. J. Watson
G. P. Margison
J. A. Rafferty
R. H. Elder
L. Cawkwell
P2860cites workHuman DNA ligase I cDNA: cloning and functional expression in Saccharomyces cerevisiaeQ24295087
Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanineQ24336908
cDNA cloning and chromosomal assignment of the human O6-methylguanine-DNA methyltransferase. cDNA expression in Escherichia coli and gene expression in human cellsQ24337212
A comprehensive set of sequence analysis programs for the VAXQ26778432
The leucine zipper: a hypothetical structure common to a new class of DNA binding proteinsQ27860587
A novel cysteine-rich sequence motifQ28264720
Cloning and expresion of cDNA for rat O6-methylguanine-DNA methyltransferaseQ28583128
Isolation and cDNA cloning of a rat O6-alkylguanine-DNA-alkyltransferase gene, molecular analysis of expression in rat liverQ33529425
Repair of O-alkylpyrimidines in mammalian cells: a present consensusQ33559258
cDNA cloning of the rat O6-methylguanine-DNA-methyltransferaseQ33583787
The role of O6-methylguanine-DNA methyltransferase in cell survival, mutagenesis and carcinogenesisQ34193304
Expression and cloning of complementary DNA for a human enzyme that repairs O6-methylguanine in DNA.Q34670992
Expression of a human O6-alkylguanine-DNA-alkyltransferase cDNA in human cells and transgenic miceQ35880142
Persistence of O 6-Ethylguanine in Rat-Brain DNA: Correlation with Nervous System-Specific Carcinogenesis by EthylnitrosoureaQ37432864
O-alkyl pyrimidines in mutagenesis and carcinogenesis: occurrence and significance.Q39743066
Mechanisms of carcinogenesis induced by alkylating agentsQ39836672
Purification of the E. coli ogt gene product to homogeneity and its rate of action on O6-methylguanine, O6-ethylguanine and O4-methylthymine in dodecadeoxyribonucleotidesQ40538566
Comparative Studies of the Hepatocarcinogen N,N-Dimethylnitrosamine in vivo: Reaction Sites in Rat Liver DNA and the Significance of their Relative StabilitiesQ41438774
Purification, structure, and biochemical properties of human O6-methylguanine-DNA methyltransferaseQ41721954
Comparison of O6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissuesQ48348433
Construction of a family of universal expression plasmid vectorsQ48387174
Presence of O6-methylguanine acceptor protein in the tissues of different classes of vertebrates and invertebratesQ48396541
Carcinogenicity of N-methyl-N-nitrosourea: possible role of excision repair of O6-methylguanine from DNA.Q48501888
Comparison of the inactivation of mammalian and bacterial O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine and O6-methylguanineQ53495189
Increased O6-alkylguanine alkyltransferase activity in Chinese hamster V79 cells following selection with chloroethylating agents.Q53524249
Specific excision of methylation products from DNA of Escherichia coli treated with N-methyl-N′-nitro-N-nitrosoguanidineQ54677618
The effects of multiple and single administration of dimethylnitrosamine to hamsters.Q54706043
Alkylation of DNA and tissue specificity in nitrosamine carcinogenesisQ71068431
Stability and capacity of dimethylnitrosamine-induced O6-methylguanine repair system in rat liverQ71096790
Species differences in the inducibility of hepatic O6-alkylguanine repair in rodentsQ71627403
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectalkyl and aryl transferasesQ78045053
P304page(s)1891-1895
P577publication date1992-04-01
1992-04-25
P1433published inNucleic Acids ResearchQ135122
P1476titleIsolation and partial characterisation of a Chinese hamster O6-alkylguanine-DNA alkyltransferase cDNA
P478volume20

Reverse relations

cites work (P2860)
Q38357198Binding and repair of O6-ethylguanine in double-stranded oligodeoxynucleotides by recombinant human O6-alkylguanine-DNA alkyltransferase do not exhibit significant dependence on sequence context
Q42274451C-terminally truncated human O6-alkylguanine-DNA alkyltransferase retains activity
Q35581164Construction and characterization of mutants of Salmonella typhimurium deficient in DNA repair of O6-methylguanine
Q40970560DNA-repair methyltransferase as a molecular device for preventing mutation and cancer
Q42046696Differential inactivation of mammalian and Escherichia coli O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine
Q41610272Immunohistological examination of the inter- and intracellular distribution of O6-alkylguanine DNA-alkyltransferase in human liver and melanoma
Q56899468New nucleotide sequence data on the EMBL File Server
Q54633191Requirement of the Pro-Cys-His-Arg sequence for O6-methylguanine-DNA methyltransferase activity revealed by saturation mutagenesis with negative and positive screening.
Q36277253Self-destruction and tolerance in resistance of mammalian cells to alkylation damage
Q53488225Site directed mutagenesis of two cysteine residues in the E. coli ogt O6-alkylguanine DNA alkyltransferase protein.
Q50132882The potential role of glycine-160 of human O6-alkylguanine-DNA alkyltransferase in reaction with O6-benzylguanine as determined by site-directed mutagenesis and molecular modelling comparisons

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