| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1990PNAS...87..686T |
| P356 | DOI | 10.1073/PNAS.87.2.686 |
| P8608 | Fatcat ID | release_keir4juya5hzpanoikwx2dc7uu |
| P3181 | OpenCitations bibliographic resource ID | 4912524 |
| P932 | PMC publication ID | 53330 |
| P698 | PubMed publication ID | 2405387 |
| P5875 | ResearchGate publication ID | 20751496 |
| P2093 | author name string | J Collier | |
| K Tano | |||
| R S Foote | |||
| S Mitra | |||
| S Shiota | |||
| P2860 | cites work | DNA sequencing with chain-terminating inhibitors | Q22066207 |
| Molecular cloning and biological characterization of a human gene, ERCC2, that corrects the nucleotide excision repair defect in CHO UV5 cells | Q24339649 | ||
| Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed | Q24611061 | ||
| Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors | Q26778475 | ||
| A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity | Q26778490 | ||
| A simple and very efficient method for generating cDNA libraries | Q27860461 | ||
| Rapid and sensitive protein similarity searches | Q27860496 | ||
| Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes | Q28131700 | ||
| Regulation and expression of the adaptive response to alkylating agents | Q28289093 | ||
| Dideoxy sequencing method using denatured plasmid templates | Q29620525 | ||
| The role of O6-methylguanine-DNA methyltransferase in cell survival, mutagenesis and carcinogenesis | Q34193304 | ||
| Rapid, large-scale purification and characterization of 'Ada protein' (O6 methylguanine-DNA methyltransferase) of E. coli | Q36057969 | ||
| Construction of an Escherichia coli K-12 ada deletion by gene replacement in a recD strain reveals a second methyltransferase that repairs alkylated DNA | Q36209000 | ||
| Characterisation and nucleotide sequence of ogt, the O6-alkylguanine-DNA-alkyltransferase gene of E. coli | Q36294780 | ||
| Effect of dose fractionation on the ethylnitrosourea induction of specific-locus mutations in mouse spermatogonia | Q36298750 | ||
| DNA-mediated transfer and expression of a human DNA repair gene that demethylates O6-methylguanine | Q36952012 | ||
| Regulation of the capacity for O6-methylguanine removal from DNA in human lymphoblastoid cells studied by cell hybridization | Q36974306 | ||
| Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis | Q37685706 | ||
| O6-Alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea | Q37686847 | ||
| DNA repair in human cells: from genetic complementation to isolation of genes | Q39560354 | ||
| Similar amino acid sequences revisited | Q43406338 | ||
| O6-alkylguanine-DNA alkyltransferase and sensitivity to procarbazine in human brain-tumor xenografts | Q43646773 | ||
| O6-methylguanine-DNA methyltransferase in human fetal tissues: fetal and maternal factors | Q48256012 | ||
| Heterogeneity of O6-alkylguanine-DNA alkyltransferase activity in peripheral blood lymphocytes: relationship between this activity in lymphocytes and in lymphoblastoid lines from normal controls and from patients with Hodgkin's disease or non-Hodgki | Q53513206 | ||
| Lack of induction of O6-methylguanine-DNA methyltransferase in mammalian cells treated with N-methyl-N'-nitro-N-nitrosoguanidine. | Q53554197 | ||
| Methylation of the O6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents. | Q53554718 | ||
| Removal of O6-methylguanine from DNA of normal and xeroderma pigmentosum-derived lymphoblastoid lines. | Q54256756 | ||
| Repair of alkylated DNA in Escherichia coli. Physical properties of O6-methylguanine-DNA methyltransferase. | Q54509469 | ||
| Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides | Q59064450 | ||
| Defective repair of alkylated DNA by human tumour and SV40-transformed human cell strains | Q59085307 | ||
| Trials, costs and complications | Q67257268 | ||
| Age-dependent modulation of tissue-specific repair activity for 3-methyladenine and O6-methylguanine in DNA in inbred mice | Q69616814 | ||
| Purification and characterization of ribulose-5-phosphate kinase from spinach | Q70125819 | ||
| High-level expression of the cloned ada gene of Escherichia coli by deletion of its regulatory sequence | Q70196134 | ||
| Repair of O6-methylguanine in DNA by demethylation is lacking in Mer- human tumor cell strains | Q71661908 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | DNA-methyltransferase activity | Q14907996 |
| O-6-methylguanine-DNA methyltransferase | Q21118735 | ||
| P304 | page(s) | 686-90 | |
| P577 | publication date | 1990-01-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine | |
| P478 | volume | 87 |
| Q40069172 | 3-aminobenzamide and/or O6-benzylguanine evaluated as an adjuvant to temozolomide or BCNU treatment in cell lines of variable mismatch repair status and O6-alkylguanine-DNA alkyltransferase activity |
| Q54178936 | A Mer- phenotype of ethionine-resistant HeLa S3 variants. |
| Q38313552 | A novel DNA damage recognition protein in Schizosaccharomyces pombe |
| Q82539025 | Accumulation of DNA methylation is associated with tumor stage in gastric cancer |
| Q77932320 | Activation of human O6-methylguanine-DNA methyltransferase gene by glucocorticoid hormone |
| Q41701560 | After X-irradiation a transient arrest of L929 cells in G2-phase coincides with a rapid elevation of the level of O6-alkylguanine-DNA alkyltransferase |
| Q43169766 | Alkylation and Carbamylation Effects of Lomustine and Its Major Metabolites and MGMT Expression in Canine Cells |
| Q41109937 | Amplification of the DNA repair gene O6-methylguanine-DNA methyltransferase associated with resistance to alkylating drugs in a mammalian cell line |
| Q36530439 | Antineoplastic Drug Resistance in Brain Tumors |
| Q47806873 | Association of MGMT promoter methylation with tumorigenesis features in patients with ovarian cancer: A systematic meta-analysis. |
| Q37522376 | BACH1 Promotes Temozolomide Resistance in Glioblastoma through Antagonizing the Function of p53. |
| Q35877937 | Bacillus subtilis ada operon encodes two DNA alkyltransferases |
| Q36122339 | Bacillus subtilis alkA gene encoding inducible 3-methyladenine DNA glycosylase is adjacent to the ada operon |
| Q38357198 | Binding and repair of O6-ethylguanine in double-stranded oligodeoxynucleotides by recombinant human O6-alkylguanine-DNA alkyltransferase do not exhibit significant dependence on sequence context |
| Q42274451 | C-terminally truncated human O6-alkylguanine-DNA alkyltransferase retains activity |
| Q24629664 | Cell cycle regulation and in vitro hybrid arrest analysis of the major human uracil-DNA glycosylase |
| Q42808106 | Characterization and chemosensitivity of two cell lines derived from human glioblastomas |
| Q35792879 | Characterization of the promoter region of the human O6-methylguanine-DNA methyltransferase gene |
| Q53756401 | Cisplatin increases sensitivity of human leukemic blasts to triazene compounds. |
| Q24561322 | Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16 |
| Q36146929 | Cloning and characterization of the Salmonella typhimurium ada gene, which encodes O6-methylguanine-DNA methyltransferase |
| Q28583128 | Cloning and expresion of cDNA for rat O6-methylguanine-DNA methyltransferase |
| Q40773392 | Contribution of O6-alkylguanine and N-alkylpurines to the formation of sister chromatid exchanges, chromosomal aberrations, and gene mutations: new insights gained from studies of genetically engineered mammalian cell lines |
| Q38587983 | DNA Repair and Chromosomal Translocations |
| Q26996421 | DNA methylation biomarkers: cancer and beyond |
| Q41311787 | DNA repair functions in heterologous cells |
| Q40636474 | DNA repair protein O6-methylguanine-DNA methyltransferase in testis and testicular tumors as determined by a novel nonradioactive assay |
| Q40970560 | DNA-repair methyltransferase as a molecular device for preventing mutation and cancer |
| Q41548366 | Depletion of O6-alkylguanine-DNA alkyltransferase correlates with potentiation of temozolomide and CCNU toxicity in human tumour cells |
| Q33264763 | Development of a novel site-specific mutagenesis assay using MALDI-ToF MS (SSMA-MS). |
| Q42046696 | Differential inactivation of mammalian and Escherichia coli O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine |
| Q49596707 | E-cigarette smoke damages DNA and reduces repair activity in mouse lung, heart, and bladder as well as in human lung and bladder cells. |
| Q22242858 | Epigenetic changes of DNA repair genes in cancer |
| Q54412464 | Expression of O⁶-methylguanine-DNA methyltransferase in childhood medulloblastoma. |
| Q35880142 | Expression of a human O6-alkylguanine-DNA-alkyltransferase cDNA in human cells and transgenic mice |
| Q46908702 | Extended continuous oral temozolomide in patients with progressive metastatic renal cell carcinoma not responding to interferon alpha 2b. |
| Q37780480 | Functions of disordered regions in mammalian early base excision repair proteins |
| Q34043392 | Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis |
| Q59134092 | Glioblastoma Chemoresistance: The Double Play by Microenvironment and Blood-Brain Barrier |
| Q45078434 | Human osteosarcoma xenografts and their sensitivity to chemotherapy |
| Q35777036 | Human uracil-DNA glycosylase complements E. coli ung mutants |
| Q37651930 | Identification of human genes involved in repair and tolerance of DNA damage |
| Q43855429 | Improvement of combination chemotherapy tolerance by introduction of polycistronic retroviral vector drug resistance genes MGMT and MDR1 into human umbilical cord blood CD34+ cells |
| Q40819181 | Increased sensitivity of transforming growth factor (TGF) beta 1 null cells to alkylating agents reveals a novel link between TGFbeta signaling and O(6)-methylguanine methyltransferase promoter hypermethylation |
| Q28268090 | Increased spontaneous mutation and alkylation sensitivity of Escherichia coli strains lacking the ogt O6-methylguanine DNA repair methyltransferase |
| Q33609622 | Increasing DNA repair methyltransferase levels via bone marrow stem cell transduction rescues mice from the toxic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea, a chemotherapeutic alkylating agent |
| Q41646564 | Induced synthesis of O6-methylguanine-DNA methyltransferase in rat hepatoma cells exposed to DNA-damaging agents |
| Q36732350 | Inducibility of the DNA repair gene encoding O6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments |
| Q40420122 | Inducible alkyltransferase DNA repair proteins in the filamentous fungus Aspergillus nidulans |
| Q73850206 | Inhibition of DNA repair as a means of increasing the antitumor activity of DNA reactive agents |
| Q24811063 | Inhibition of O6-methylguanine-DNA methyltransferase by an alkyltransferase-like protein from Escherichia coli |
| Q33213310 | Isolation and partial characterisation of a Chinese hamster O6-alkylguanine-DNA alkyltransferase cDNA |
| Q33258127 | Isolation and structure of a cDNA expressing a mammalian 3-methyladenine-DNA glycosylase |
| Q33262722 | Isolation of cDNA clones encoding an enzyme from bovine cells that repairs oxidative DNA damagein vitro: homology with bacterial repair enzymes |
| Q51604204 | MGMT promoter methylation and immunoexpression in aggressive pituitary adenomas and carcinomas. |
| Q36812588 | MGMT: a personal perspective |
| Q34310201 | MGMT: its role in cancer aetiology and cancer therapeutics |
| Q33347264 | Marked inactivation of O6-alkylguanine-DNA alkyltransferase activity with protracted temozolomide schedules |
| Q28608973 | Mechanisms of human DNA repair: an update |
| Q40023435 | Methylation of discrete regions of the O6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene |
| Q48701663 | Methylation status of O6-methylguanine-DNA-methyl transferase promoter region in non-small-cell lung cancer patients with brain metastasis |
| Q36242500 | Molecular analysis of Bacillus subtilis ada mutants deficient in the adaptive response to simple alkylating agents |
| Q35115409 | Molecular devices for high fidelity of DNA replication and gene expression |
| Q37861732 | Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools |
| Q53443057 | Mutations of O6-methylguanine-DNA methyltransferase gene in esophageal cancer tissues from Northern China. |
| Q37261125 | New (alternative) temozolomide regimens for the treatment of glioma |
| Q93511366 | New nucleotide sequence data on the EMBL File Server |
| Q36801155 | Novel human DNA alkyltransferases obtained by random substitution and genetic selection in bacteria |
| Q41771536 | Novel synthesis of O6-alkylguanine containing oligodeoxyribonucleotides as substrates for the human DNA repair protein, O6-methylguanine DNA methyltransferase (MGMT). |
| Q43861422 | O(6)-methylguanine-DNA methyltransferase (MGMT) as a determinant of resistance to camptothecin derivatives |
| Q41645855 | O6-Alkylguanine-DNA alkyltransferase content in synchronised human cancer cells |
| Q72067168 | Organization and expression of the human gene for O6-methylguanine-DNA methyltransferase |
| Q41964598 | Phosphorylation of methylated-DNA-protein-cysteine S-methyltransferase at serine-204 significantly increases its resistance to proteolytic digestion |
| Q39993380 | Potentiation of temozolomide and BCNU cytotoxicity by O(6)-benzylguanine: a comparative study in vitro |
| Q43505054 | Preliminary individual adjuvant therapy for gliomas based on the results of molecular biological analyses for drug-resistance genes |
| Q27936494 | Primary sequence and biological functions of a Saccharomyces cerevisiae O6-methylguanine/O4-methylthymine DNA repair methyltransferase gene |
| Q36261945 | Prognosis value of MGMT promoter methylation for patients with lung cancer: a meta-analysis |
| Q40784270 | Promoter hypermethylation of MGMT is associated with protein loss in gastric carcinoma |
| Q46878705 | Quantitation of O6-methylguanine-DNA methyltransferase gene messenger RNA in gliomas by means of real-time RT-PCR and clinical response to nitrosoureas |
| Q38345918 | Recombinant human O6-alkylguanine-DNA alkyltransferase (AGT), Cys145-alkylated AGT and Cys145 --> Met145 mutant AGT: comparison by isoelectric focusing, CD and time-resolved fluorescence spectroscopy |
| Q32128152 | Reduction of BCNU toxicity to lung cells by high-level expression of O(6)-methylguanine-DNA methyltransferase |
| Q39716063 | Regulation of O6-methylguanine-DNA methyltransferase by methionine in human tumour cells |
| Q34478948 | Regulation of expression of O6-methylguanine-DNA methyltransferase and the treatment of glioblastoma (Review). |
| Q38309365 | Regulation of the human O(6)-methylguanine-DNA methyltransferase gene by transcriptional coactivators cAMP response element-binding protein-binding protein and p300. |
| Q37313222 | Relationship between O6-alkylguanine-DNA alkyltransferase activity and N-methyl-N'-nitro-N-nitrosoguanidine-induced mutation, transformation, and cytotoxicity in C3H/10T1/2 cells expressing exogenous alkyltransferase genes |
| Q24544017 | Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA |
| Q33926831 | Repair of O6-ethylguanine in DNA protects rat 208F cells from tumorigenic conversion by N-ethyl-N-nitrosourea |
| Q41027968 | Repair of cyclobutane pyrimidine dimers in the O6-methylguanine-DNA methyltransferase (MGMT) gene of MGMT proficient and deficient human cell lines and comparison with the repair of other genes and a repressed X-chromosomal locus |
| Q26822957 | Repair of oxidative DNA damage and cancer: recent progress in DNA base excision repair |
| Q39094431 | Retroviral Vectors for Cancer Gene Therapy |
| Q36277253 | Self-destruction and tolerance in resistance of mammalian cells to alkylation damage |
| Q34826415 | Specificities of human, rat and E. coli O6-methylguanine-DNA methyltransferases towards the repair of O6-methyl and O6-ethylguanine in DNA. |
| Q35593508 | Suppression of Escherichia coli alkB mutants by Saccharomyces cerevisiae genes |
| Q44454358 | Synthesis and preliminary biological evaluation of radiolabeled O6-benzylguanine derivatives, new potential PET imaging agents for the DNA repair protein O6-alkylguanine-DNA alkyltransferase in breast cancer |
| Q26821907 | The maintenance of mitochondrial DNA integrity--critical analysis and update |
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| Q42826720 | Transforming activity of a synthetic c-Ha-ras gene containing O6-methylguanine in codon 12. |
| Q37129807 | Treatment resistance mechanisms of malignant glioma tumor stem cells |
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| Q42925815 | p53-Mediated down-regulation of the human DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) via interaction with Sp1 transcription factor |
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