DNA repair protein O6-methylguanine-DNA methyltransferase in testis and testicular tumors as determined by a novel nonradioactive assay

scientific article published on October 2003

DNA repair protein O6-methylguanine-DNA methyltransferase in testis and testicular tumors as determined by a novel nonradioactive assay is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0003-2697(03)00432-9
P698PubMed publication ID12963053

P50authorKai JohnssonQ29841297
P2093author name stringBernd Kaina
Walburgis Brenner
Georg Nagel
P2860cites workO6-methylguanine-DNA methyltransferase activity in breast and brain tumors.Q55480784
Assay for O6-alkylguanine-DNA-alkyltransferase using oligonucleotides containing O6-methylguanine in a BamHI recognition site as substrateQ67586871
Protective effect of O6-methylguanine-DNA methyltransferase (MGMT) on the cytotoxic and recombinogenic activity of different antineoplastic drugsQ71058150
Chromosomal instability, reproductive cell death and apoptosis induced by O6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and modelsQ74063639
O6-alkylguanine DNA lesions trigger apoptosisQ74302180
Frequent promoter hypermethylation of the O6-Methylguanine-DNA Methyltransferase (MGMT) gene in testicular cancerQ78666620
Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanineQ24336908
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
A novel fluorometric oligonucleotide assay to measure O( 6)-methylguanine DNA methyltransferase, methylpurine DNA glycosylase, 8-oxoguanine DNA glycosylase and abasic endonuclease activities: DNA repair status in human breast carcinoma cells overexpQ33939316
Variability and regulation of O6-alkylguanine-DNA alkyltransferaseQ34194319
O6-alkylguanine-DNA alkyltransferase: role in carcinogenesis and chemotherapyQ34561510
Inducibility of the DNA repair gene encoding O6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatmentsQ36732350
Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agentsQ37939678
Real-time fluorescence assay for O6-alkylguanine-DNA alkyltransferase.Q40871378
Chemoprotective gene transfer I: transduction of human haemopoietic progenitors with O6-benzylguanine-resistant O6-alkylguanine-DNA alkyltransferase attenuates the toxic effects of O6-alkylating agents in vitroQ41007279
Activity of O(6)-methylguanine-DNA methyltransferase in relation to p53 status and therapeutic response in ovarian cancerQ42474663
Phase I trial of O6-benzylguanine for patients undergoing surgery for malignant gliomaQ48349949
Correlation of tumor O6 methylguanine-DNA methyltransferase levels with survival of malignant astrocytoma patients treated with bis-chloroethylnitrosourea: a Southwest Oncology Group studyQ48371882
Long-time expression of DNA repair enzymes MGMT and APE in human peripheral blood mononuclear cells.Q53395895
Induction of the alkyltransferase (MGMT) gene by DNA damaging agents and the glucocorticoid dexamethasone and comparison with the response of base excision repair genes.Q53449965
A simplified assay for O6-methylguanine-DNA methyltransferase activity and its application to human neoplastic and non-neoplastic tissues.Q53551171
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)38-43
P577publication date2003-10-01
P1433published inAnalytical BiochemistryQ485215
P1476titleDNA repair protein O6-methylguanine-DNA methyltransferase in testis and testicular tumors as determined by a novel nonradioactive assay
P478volume321

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cites work (P2860)
Q89782508A "Clickable" Probe for Active MGMT in Glioblastoma Demonstrates Two Discrete Populations of MGMT
Q39376801A mechanism-based fluorescent probe for labeling O6-methylguanine-DNA methyltransferase in live cells
Q37412218Development of an O(6)-alkylguanine-DNA alkyltransferase assay based on covalent transfer of the benzyl moiety from [benzene-3H]O(6)-benzylguanine to the protein
Q36389617Direct reversal of DNA alkylation damage
Q28551141Fluorogenic Real-Time Reporters of DNA Repair by MGMT, a Clinical Predictor of Antitumor Drug Response
Q38851881Impact of O6-methylguanine-DNA methyltransferase expression on the drug resistance of clear cell renal cell carcinoma
Q41045107Protein sensing in living cells by molecular rotor-based fluorescence-switchable chemical probes

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