Chemoprotective gene transfer I: transduction of human haemopoietic progenitors with O6-benzylguanine-resistant O6-alkylguanine-DNA alkyltransferase attenuates the toxic effects of O6-alkylating agents in vitro

scientific article published on June 1998

Chemoprotective gene transfer I: transduction of human haemopoietic progenitors with O6-benzylguanine-resistant O6-alkylguanine-DNA alkyltransferase attenuates the toxic effects of O6-alkylating agents in vitro is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1052108900
P356DOI10.1038/SJ.GT.3300698
P698PubMed publication ID9747464
P5875ResearchGate publication ID13539366

P2093author name stringN Thatcher
G P Margison
J A Rafferty
T M Dexter
L J Fairbairn
N Chinnasamy
L S Lashford
I Hickson
P433issue6
P304page(s)835-841
P577publication date1998-06-01
P1433published inGene TherapyQ15763095
P1476titleChemoprotective gene transfer I: transduction of human haemopoietic progenitors with O6-benzylguanine-resistant O6-alkylguanine-DNA alkyltransferase attenuates the toxic effects of O6-alkylating agents in vitro
P478volume5

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cites work (P2860)
Q40799213A novel dual function retrovirus expressing multidrug resistance 1 and O6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents
Q36396542Altered DNA binding and amplification of human breast cancer suppressor gene BRCA1 induced by a novel antitumor compound, [Ru(η(6)-p-phenylethacrynate)Cl(2)(pta)].
Q40636474DNA repair protein O6-methylguanine-DNA methyltransferase in testis and testicular tumors as determined by a novel nonradioactive assay
Q33892816Gene transfer to suppress bone marrow alkylation sensitivity.
Q43855429Improvement of combination chemotherapy tolerance by introduction of polycistronic retroviral vector drug resistance genes MGMT and MDR1 into human umbilical cord blood CD34+ cells
Q43983999Interaction of mammalian O(6)-alkylguanine-DNA alkyltransferases with O(6)-benzylguanine
Q36812597Live and let die: in vivo selection of gene-modified hematopoietic stem cells via MGMT-mediated chemoprotection
Q45889046Modulation of O6-alkylating agent induced clastogenicity by enhanced DNA repair capacity of bone marrow cells
Q30671001O6-Benzylguanine potentiates BCNU but not busulfan toxicity in hematopoietic stem cells
Q33888666Overexpression of enzymes that repair endogenous damage to DNA.
Q45859509Protection of CHO cells by mutant forms of O6-alkylguanine-DNA alkyltransferase from killing by 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) plus O6-benzylguanine or O6-benzyl-8-oxoguanine
Q40751559Retroviral transfer and expression of human MDR-1 in a murine haemopoietic stem cell line does not alter factor dependence, growth or differentiation characteristics

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