scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0006-2952(02)00906-1 |
P698 | PubMed publication ID | 11996884 |
P2093 | author name string | Anthony E Pegg | |
Natalia A Loktionova | |||
P2860 | cites work | Hyperthermostable protein structure maintained by intra and inter-helix ion-pairs in archaeal O6-methylguanine-DNA methyltransferase | Q27619727 |
Crystal structure of the human O(6)-alkylguanine-DNA alkyltransferase | Q27620779 | ||
Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding | Q27622042 | ||
Increased spontaneous mutation and alkylation sensitivity of Escherichia coli strains lacking the ogt O6-methylguanine DNA repair methyltransferase | Q28268090 | ||
Repair of DNA containing O6-alkylguanine | Q28284603 | ||
Regulation and expression of the adaptive response to alkylating agents | Q28289093 | ||
Applied molecular evolution of O6-benzylguanine-resistant DNA alkyltransferases in human hematopoietic cells | Q30663736 | ||
Characterization of cDNA encoding mouse DNA repair protein O6-methylguanine-DNA methyltransferase and high-level expression of the wild-type and mutant proteins in Escherichia coli | Q30736503 | ||
Protection and in vivo selection of hematopoietic stem cells using temozolomide, O6-benzylguanine, and an alkyltransferase-expressing retroviral vector | Q31853786 | ||
Phase I trial of carmustine plus O6-benzylguanine for patients with recurrent or progressive malignant glioma | Q33334642 | ||
Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents | Q33689518 | ||
Conserved structural motifs governing the stoichiometric repair of alkylated DNA by O(6)-alkylguanine-DNA alkyltransferase | Q34006340 | ||
The suicidal DNA repair methyltransferases of microbes | Q36200499 | ||
Mechanism of inactivation of human O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine | Q38314205 | ||
Genetic polymorphism of human O6-alkylguanine-DNA alkyltransferase: identification of a missense variation in the active site region | Q38325818 | ||
Inactivation of O6-alkylguanine-DNA alkyltransferase. 1. Novel O6-(hetarylmethyl)guanines having basic rings in the side chain | Q40987553 | ||
Chemoprotective gene transfer I: transduction of human haemopoietic progenitors with O6-benzylguanine-resistant O6-alkylguanine-DNA alkyltransferase attenuates the toxic effects of O6-alkylating agents in vitro | Q41007279 | ||
Ubiquitination-dependent proteolysis of O6-methylguanine-DNA methyltransferase in human and murine tumor cells following inactivation with O6-benzylguanine or 1,3-bis(2-chloroethyl)-1-nitrosourea | Q41236881 | ||
A polymorphism at codon 160 of human O6 methylguanine-DNA methyltransferase gene in young patients with adult type cancers and functional assay | Q41671919 | ||
Differential inactivation of mammalian and Escherichia coli O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine | Q42046696 | ||
Inactivation of O(6)-methylguanine-DNA methyltransferase by glucose-conjugated inhibitors | Q43658868 | ||
Protection of CHO cells by mutant forms of O6-alkylguanine-DNA alkyltransferase from killing by 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) plus O6-benzylguanine or O6-benzyl-8-oxoguanine | Q45859509 | ||
Characterization of the P140K, PVP(138-140)MLK, and G156A O6-methylguanine-DNA methyltransferase mutants: implications for drug resistance gene therapy | Q45863801 | ||
Characterization of human polymorphic DNA repair methyltransferase. | Q53411914 | ||
8-Substituted O6-benzylguanine, substituted 6(4)-(benzyloxy)pyrimidine, and related derivatives as inactivators of human O6-alkylguanine-DNA alkyltransferase. | Q53466577 | ||
Structural features of substituted purine derivatives compatible with depletion of human O6-alkylguanine-DNA alkyltransferase | Q53486098 | ||
Comparison of the inactivation of mammalian and bacterial O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine and O6-methylguanine | Q53495189 | ||
Use of antibodies to human O6-alkylguanine-DNA alkyltransferase to study the content of this protein in cells treated with O6-benzylguanine or N-methyl-N'-nitro-N-nitrosoguanidine | Q67975150 | ||
Polymorphism in the human O6-methylguanine-DNA methyltransferase gene detected by PCR-SSCP analysis | Q71690609 | ||
Activation of human O6-alkylguanine-DNA alkyltransferase by DNA | Q72061933 | ||
The role of two conserved amino acids, glutamine 90 and asparagine 137, in O6-methylguanine-DNA methyltransferase stability, activity and substrate specificity | Q72711282 | ||
Substituted O6-benzylguanine derivatives and their inactivation of human O6-alkylguanine-DNA alkyltransferase | Q72774928 | ||
O6-benzylguanine in humans: metabolic, pharmacokinetic, and pharmacodynamic findings | Q74545960 | ||
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1431-1442 | |
P577 | publication date | 2002-04-01 | |
P1433 | published in | Biochemical Pharmacology | Q864229 |
P1476 | title | Interaction of mammalian O(6)-alkylguanine-DNA alkyltransferases with O(6)-benzylguanine | |
P478 | volume | 63 |
Q43104952 | Active-site alkylation destabilizes human O6-alkylguanine DNA alkyltransferase |
Q59198949 | Chapter 5 Molecular Mechanisms of 4‐(Methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone‐Induced Lung Carcinogenesis |
Q36012002 | DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by O6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy |
Q37038938 | Tumor-associated mutations in O⁶ -methylguanine DNA-methyltransferase (MGMT) reduce DNA repair functionality |
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