O(6)-methylguanine-DNA methyltransferase (MGMT) as a determinant of resistance to camptothecin derivatives

scientific article published in January 2002

O(6)-methylguanine-DNA methyltransferase (MGMT) as a determinant of resistance to camptothecin derivatives is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1349-7006.2002.TB01205.X
P932PMC publication ID5926864
P698PubMed publication ID11802813
P5875ResearchGate publication ID246816260

P50authorAlex SparreboomQ71780219
Jaap VerweijQ98683725
P2093author name stringKeiji Tanimoto
Ryo Okamoto
Masahiko Nishiyama
Wataru Yamamoto
Tatsunori Okamura
Takashi Sekikawa
Hiroshi Takano
Ji-Seon Park
P2860cites workA multidrug resistance transporter from human MCF-7 breast cancer cellsQ22008574
Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanineQ24336908
p53 is involved in regulation of the DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agentsQ28579401
Suppression of human colorectal carcinoma cell growth by wild-type p53Q29618318
Role of erythrocytes and serum proteins in the kinetic profile of total 9-amino-20(S)-camptothecin in humansQ33179201
Structure, Function, and Inhibition of O6-Alkylguanine-DNA AlkyltransferaseQ40473972
The current status of camptothecin analogues as antitumor agentsQ40851253
Characterization of a human small-cell lung cancer cell line resistant to a new water-soluble camptothecin derivative, DX-8951fQ40978962
The role of glucuronidation in 7-ethyl-10-hydroxycamptothecin resistance in vitroQ41064018
Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphomaQ41090576
DX-8951f, a water-soluble camptothecin analog, exhibits potent antitumor activity against a human lung cancer cell line and its SN-38-resistant variantQ41094672
Molecular targeting of mitomycin C chemotherapyQ41094677
Extended depletion of O6-methylguanine-DNA methyltransferase activity following O6-benzyl-2'-deoxyguanosine or O6-benzylguanine combined with streptozotocin treatment enhances 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity.Q41448559
An overview of the clinical pharmacology of topotecanQ41448813
Differential inactivation of O6-methylguanine-DNA methyltransferase activity by O6-arylmethylguanines.Q54162250
A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo.Q54167076
NADPH/quinone oxidoreductase is a priority target of glioblastoma chemotherapy.Q55476248
Measurement of O6-alkylguanine-DNA alkyltransferase activity in human cells and tumor tissues by restriction endonuclease inhibitionQ69811351
Role of O6-alkylguanine-DNA alkyltransferase in protecting against cyclophosphamide-induced toxicity and mutagenicityQ77973119
P433issue1
P1104number of pages10
P304page(s)93-102
P577publication date2002-01-01
P1433published inJapanese Journal of Cancer ResearchQ26842384
P1476titleO(6)-methylguanine-DNA methyltransferase (MGMT) as a determinant of resistance to camptothecin derivatives
P478volume93

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