| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1996PNAS...93..206M |
| P356 | DOI | 10.1073/PNAS.93.1.206 |
| P932 | PMC publication ID | 40207 |
| P698 | PubMed publication ID | 8552605 |
| P5875 | ResearchGate publication ID | 14647131 |
| P2093 | author name string | L Samson | |
| D A Williams | |||
| J P Carney | |||
| M R Kelley | |||
| R Maze | |||
| B J Glassner | |||
| P2860 | cites work | Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine | Q24336908 |
| Regulation and expression of the adaptive response to alkylating agents | Q28289093 | ||
| Cloning and characterization of a mouse 3-methyladenine/7-methyl-guanine/3-methylguanine DNA glycosylase cDNA whose gene maps to chromosome 11 | Q28513792 | ||
| Regulation of repair of alkylation damage in mammalian genomes | Q28647295 | ||
| Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial | Q33453675 | ||
| Bone marrow extracellular matrix molecules improve gene transfer into human hematopoietic cells via retroviral vectors | Q34138051 | ||
| O6 alkylguanine-DNA alkyltransferase activity in human myeloid cells | Q34568108 | ||
| Formation of covalent complexes between human O6-alkylguanine-DNA alkyltransferase and BCNU-treated defined length synthetic oligodeoxynucleotides | Q36058843 | ||
| Protection of bone marrow transplant recipients from lethal doses of methotrexate by the generation of methotrexate-resistant bone marrow | Q36353760 | ||
| Protection against chloroethylnitrosourea cytotoxicity by eukaryotic 3-methyladenine DNA glycosylase | Q36730360 | ||
| A safe packaging line for gene transfer: separating viral genes on two different plasmids | Q36865708 | ||
| Suppression of human DNA alkylation-repair defects by Escherichia coli DNA-repair genes | Q37392653 | ||
| DNA alkylation by the haloethylnitrosoureas: nature of modifications produced and their enzymatic repair or removal | Q37984292 | ||
| Autotransplants in leukaemia | Q38359403 | ||
| 1,3-Bis(2-Chloroethyl)-1-Nitrosourea (Bcnu) And Other Nitrosoureas In Cancer Treatment: A Review | Q39919334 | ||
| Cross-linking of DNA induced by chloroethyinitrosourea is prevented by O6-methyiguanine-DNA methyttransferase | Q40494530 | ||
| Nitrosoureas: a review of experimental antitumor activity | Q40573799 | ||
| Stem cell factor, interleukin-3, and interleukin-6 promote retroviral-mediated gene transfer into murine hematopoietic stem cells | Q41613785 | ||
| DNA cross-linking and monoadduct repair in nitrosourea-treated human tumour cells | Q41614931 | ||
| Differential effects of cytotoxic agents on hematopoietic progenitors | Q41634798 | ||
| Gene transfer into the hematopoietic system | Q41644419 | ||
| Retroviral gene transfer of human adenosine deaminase in murine hematopoietic cells: effect of selectable marker sequences on long-term expression | Q41674345 | ||
| Retrovirus-mediated expression of a DNA repair protein in bone marrow protects hematopoietic cells from nitrosourea-induced toxicity in vitro and in vivo. | Q42826764 | ||
| Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1 | Q43662819 | ||
| Construction and characterization of retroviral vectors expressing biologically active human interleukin-12. | Q45868776 | ||
| Comparison of O6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues | Q48348433 | ||
| Developmental potential and dynamic behavior of hematopoietic stem cells. | Q52261166 | ||
| Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/Wv mice. | Q54134810 | ||
| The Biology of Hematopoietic Stem Cells | Q58043095 | ||
| Use of antibodies to human O6-alkylguanine-DNA alkyltransferase to study the content of this protein in cells treated with O6-benzylguanine or N-methyl-N'-nitro-N-nitrosoguanidine | Q67975150 | ||
| Measurement of O6-alkylguanine-DNA alkyltransferase activity in human cells and tumor tissues by restriction endonuclease inhibition | Q69811351 | ||
| Hematopoietic stem cell deficit of transplanted bone marrow previously exposed to cytotoxic agents | Q70565169 | ||
| Functional isolation and characterization of human hematopoietic stem cells | Q71666169 | ||
| Comparative effects of in vivo treatment using interleukin-11 and stem cell factor on reconstitution in mice after bone marrow transplantation | Q72088947 | ||
| Increased survival and multilineage hematopoietic protection from delayed and severe myelosuppressive effects of a nitrosourea with recombinant interleukin-11 | Q72149170 | ||
| Gene marking to determine whether autologous marrow infusion restores long-term haemopoiesis in cancer patients | Q72656870 | ||
| High proliferative potential colony-forming cell heterogeneity identified using counterflow centrifugal elutriation | Q72827245 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | chemotherapy | Q974135 |
| P1104 | number of pages | 5 | |
| P304 | page(s) | 206-210 | |
| P577 | publication date | 1996-01-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Increasing DNA repair methyltransferase levels via bone marrow stem cell transduction rescues mice from the toxic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea, a chemotherapeutic alkylating agent | |
| P478 | volume | 93 |
| Q40799213 | A novel dual function retrovirus expressing multidrug resistance 1 and O6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents |
| Q45857890 | A pilot study of dose-intensified procarbazine, CCNU, vincristine for poor prognosis brain tumors utilizing fibronectin-assisted, retroviral-mediated modification of CD34+ peripheral blood cells with O6-methylguanine DNA methyltransferase |
| Q34088805 | A rapid survival assay to measure drug-induced cytotoxicity and cell cycle effects |
| Q43169766 | Alkylation and Carbamylation Effects of Lomustine and Its Major Metabolites and MGMT Expression in Canine Cells |
| Q74813053 | Assessment of resistance induction to cytosine arabinoside following transfer and overexpression of the deoxycytidylate deaminase gene in vitro |
| Q36651488 | Balancing repair and tolerance of DNA damage caused by alkylating agents |
| Q41349090 | Chemoprotection of normal tissues by transfer of drug resistance genes |
| Q74063639 | Chromosomal instability, reproductive cell death and apoptosis induced by O6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and models |
| Q38768165 | Co-expression of MGMT(P140K) and alpha-L-iduronidase in primary hepatocytes from mucopolysaccharidosis type I mice enables efficient selection with metabolic correction |
| Q41311787 | DNA repair functions in heterologous cells |
| Q47928447 | Efficient protection of cells from the genotoxicity of nitrosoureas by the retrovirus-mediated transfer of human O6-methylguanine-DNA methyltransferase using bicistronic vectors with human multidrug resistance gene 1. |
| Q34552694 | Enhancement of radiosensitivity in human glioblastoma cells by the DNA N-mustard alkylating agent BO-1051 through augmented and sustained DNA damage response. |
| Q36911194 | Gene therapy approaches for stem cell protection |
| Q33702182 | Gene therapy for chronic myelogenous leukemia |
| Q34216677 | Gene transfer and the treatment of haematological malignancy |
| Q33892816 | Gene transfer to suppress bone marrow alkylation sensitivity. |
| Q40865994 | Hematopoietic progenitor cell transplantation in breast cancer: current status and future directions |
| Q44110257 | Hematoprotection and enrichment of transduced cells in vivo after gene transfer of MGMT(P140K) into hematopoietic stem cells |
| Q33357339 | Hematoprotection by Transfer of Drug-Resistance Genes |
| Q30650758 | Improving enzymes for cancer gene therapy |
| Q73850206 | Inhibition of DNA repair as a means of increasing the antitumor activity of DNA reactive agents |
| Q34649263 | Knockdown of HPRT for selection of genetically modified human hematopoietic progenitor cells |
| Q45889046 | Modulation of O6-alkylating agent induced clastogenicity by enhanced DNA repair capacity of bone marrow cells |
| Q42168154 | Myeloablation is not required to select and maintain expression of the drug-resistance gene, mutant MGMT, in primary and secondary recipients |
| Q38831996 | Novel 19 F-MRS β-galactosidase reporter molecules incorporated nitrogen mustard analogues. |
| Q33888666 | Overexpression of enzymes that repair endogenous damage to DNA. |
| Q52730088 | Programming of Cell Resistance to Genotoxic and Oxidative Stress. |
| Q40686874 | Protection of hematopoietic cells from O(6)-alkylation damage by O(6)-methylguanine DNA methyltransferase gene transfer: studies with different O(6)-alkylating agents and retroviral backbones |
| Q53304529 | Retroviral Expression of Arginine Decarboxylase Attenuates Oxidative Burden in Mouse Cortical Neural Stem Cells |
| Q41712927 | Retroviral gene therapy in hematopoietic diseases |
| Q35943817 | Retroviral transduction of a mutant methylguanine DNA methyltransferase gene into human CD34 cells confers resistance to O6-benzylguanine plus 1,3-bis(2-chloroethyl)-1-nitrosourea |
| Q30454407 | Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents. |
| Q35990723 | Stable differentiation and clonality of murine long-term hematopoiesis after extended reduced-intensity selection for MGMT P140K transgene expression |
| Q43702277 | Synthesis and antitumor activity of novel nitrogen mustard-linked chalcones |
| Q53038908 | Synthesis and cytotoxicity evaluation of naphthalimide derived N-mustards. |
| Q37780712 | Targeting O⁶-methylguanine-DNA methyltransferase with specific inhibitors as a strategy in cancer therapy |
| Q48879846 | Targeting autophagy enhances BO-1051-induced apoptosis in human malignant glioma cells. |
| Q33771774 | The cellular response to p53: the decision between life and death |
| Q38518565 | Transcription factors NF-YA regulate the induction of human OGG1 following DNA-alkylating agent methylmethane sulfonate (MMS) treatment. |
| Q36248825 | Vector design for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells |
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