Evidence from bioinformatics, expression and inhibition studies of phosphoinositide-3 kinase signalling in Giardia intestinalis

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Evidence from bioinformatics, expression and inhibition studies of phosphoinositide-3 kinase signalling in Giardia intestinalis is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1014306208
P356DOI10.1186/1471-2180-6-45
P932PMC publication ID1483827
P698PubMed publication ID16707026
P5875ResearchGate publication ID7074667

P50authorMark van der GiezenQ42373981
Sarah J TarrQ55100042
P2093author name stringJorge Tovar
Mark R Crompton
Siân S E Cox
P2860cites workUnusual organization of a developmentally regulated mitochondrial RNA polymerase (TBMTRNAP) gene in Trypanosoma bruceiQ37344707
Cholesterol starvation induces differentiation of the intestinal parasite Giardia lambliaQ37429045
A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and developmentQ40017367
Analysis of consensus sequence patterns inGiardia cytoskeletongene promotersQ40395194
Calcium signaling in excystation of the early diverging eukaryote, Giardia lambliaQ42527232
Inferring protein function from genomic sequence: Giardia lamblia expresses a phosphatidylinositol kinase-related kinase similar to yeast and mammalian TOR.Q44241759
Protein kinase B from Giardia intestinalis.Q46600006
A comparison of demethoxyviridin and wortmannin as inhibitors of phosphatidylinositol 3-kinase.Q52543268
Identification, characteristic and phylogenetic analysis of type II DNA topoisomerase gene in Giardia lamblia.Q54656367
Structural insights into phosphoinositide 3-kinase catalysis and signallingQ57648104
In vitro encystation of Giardia lamblia: large-scale production of in vitro cysts and strain and clone differences in encystation efficiencyQ67835486
Changes in lipid composition during in vitro encystation and fatty acid desaturase activity of Giardia lambliaQ71727300
Neurite outgrowth of PC12 cells is suppressed by wortmannin, a specific inhibitor of phosphatidylinositol 3-kinaseQ72068658
Role of exogenous inositol and phosphatidylinositol in glycosylphosphatidylinositol anchor synthesis of GP49 by Giardia lambliaQ73280907
Casein kinase I is anchored on axonemal doublet microtubules and regulates flagellar dynein phosphorylation and activityQ73905834
Possible role of calmodulin in excystation of Giardia lambliaQ77392519
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Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and StaurosporineQ27628650
Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gammaQ27629132
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A Simple, Fast, and Accurate Algorithm to Estimate Large Phylogenies by Maximum LikelihoodQ27861000
The phosphoinositide (PI) 3-kinase familyQ28182525
Synthesis and function of 3-phosphorylated inositol lipidsQ28200755
Specificity and mechanism of action of some commonly used protein kinase inhibitorsQ28344791
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Protein kinases as drug targets in parasitic protozoaQ30862734
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Possible roles of protein kinase A in cell motility and excystation of the early diverging eukaryote Giardia lambliaQ30975342
The Giardia duodenalis 14-3-3 protein is post-translationally modified by phosphorylation and polyglycylation of the C-terminal tailQ33230030
GTPases in protozoan parasites: tools for cell biology and chemotherapy.Q33719343
Methods for cultivation of luminal parasitic protists of clinical importanceQ33906770
Phosphoinositide 3-kinase signalling pathwaysQ33940898
A spliceosomal intron in Giardia lambliaQ34019814
Cellular and transcriptional changes during excystation of Giardia lamblia in vitro.Q34066366
Origins of Prokaryotes, Eukaryotes, Mitochondria, and ChloroplastsQ34102135
Potential involvement of extracellular signal-regulated kinase 1 and 2 in encystation of a primitive eukaryote, Giardia lamblia. Stage-specific activation and intracellular localizationQ34156053
Leading the way: Directional sensing through phosphatidylinositol 3-kinase and other signaling pathways.Q35189957
Isoform-specific phosphoinositide 3-kinase inhibitors as therapeutic agents.Q35193663
Ultrastructural localization of giardins to the edges of disk microribbons of Giarida lamblia and the nucleotide and deduced protein sequence of alpha giardinQ36221930
Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiaeQ36775602
P921main subjectbioinformaticsQ128570
Giardia lambliaQ155630
Giardia intestinalisQ10289451
P304page(s)45
P577publication date2006-05-18
P1433published inBMC MicrobiologyQ15759430
P1476titleEvidence from bioinformatics, expression and inhibition studies of phosphoinositide-3 kinase signalling in Giardia intestinalis
P478volume6

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cites work (P2860)
Q30395256Bioinformatics and Drug Discovery
Q58455832Fecal Matter Implantation as a Way to Fight Diarrhea-Causing Microorganisms
Q37297634Genome-wide analysis of the phosphoinositide kinome from two ciliates reveals novel evolutionary links for phosphoinositide kinases in eukaryotic cells
Q51893182Identification and characterization of a FYVE domain from the early diverging eukaryote Giardia lamblia.
Q35093420Lipid metabolism in Giardia: a post-genomic perspective.
Q58789527Membrane-Associated Proteins in
Q89857597Phosphoinositide-binding proteins mark, shape and functionally modulate highly-diverged endocytic compartments in the parasitic protist Giardia lamblia
Q28649653The cell survival pathways of the primordial RNA-DNA complex remain conserved in the extant genomes and may function as proto-oncogenes
Q39183588The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology.
Q35072257Transcriptional analysis of three major putative phosphatidylinositol kinase genes in a parasitic protozoan, Giardia lamblia

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