| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Cantrell DA | |
| P433 | issue | Pt 8 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1439-1445 | |
| P577 | publication date | 2001-04-01 | |
| P1433 | published in | Journal of Cell Science | Q1524177 |
| P1476 | title | Phosphoinositide 3-kinase signalling pathways | |
| P478 | volume | 114 |
| Q58777532 | A Novel Tetramethylpyrazine Derivative Protects Against Glutamate-Induced Cytotoxicity Through PGC1α/Nrf2 and PI3K/Akt Signaling Pathways |
| Q35036951 | A quantitative assessment of costimulation and phosphatase activity on microclusters in early T cell signaling. |
| Q36482989 | A tug-of-war between the host and the pathogen generates strategic hotspots for the development of novel therapeutic interventions against infectious diseases. |
| Q34784803 | A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate |
| Q36670941 | AKT inhibition is associated with chemosensitisation in the pancreatic cancer cell line MIA-PaCa-2 |
| Q37103690 | Actin cytoskeletal mediators of motility and invasion amplified and overexpressed in head and neck cancer |
| Q36771298 | Actin filament dynamics impacts keratinocyte stem cell maintenance |
| Q37369171 | Activation of phosphatidylinositol 3-kinase/protein kinase B by corticotropin-releasing factor in human monocytes |
| Q34476441 | Adapters in the organization of mast cell signaling |
| Q27323171 | Adult subependymal neural precursors, but not differentiated cells, undergo rapid cathodal migration in the presence of direct current electric fields |
| Q34623930 | Akt activation is required for TGF-β1-induced osteoblast differentiation of MC3T3-E1 pre-osteoblasts |
| Q36161549 | Akt as a mediator of cell death |
| Q33871508 | Akt1 and Akt2 promote peripheral B-cell maturation and survival |
| Q58746553 | Akt2 Regulates the Differentiation and Function of NKT17 Cells via FoxO-1-ICOS Axis |
| Q36303948 | All PI3Kinase signaling is not mTOR: dissecting mTOR-dependent and independent signaling pathways in T cells |
| Q48128271 | An Autoinhibitory Role for the Pleckstrin Homology Domain of Interleukin-2-Inducible Tyrosine Kinase and Its Interplay with Canonical Phospholipid Recognition. |
| Q35092971 | Androgen-independent prostate cancer: potential role of androgen and ErbB receptor signal transduction crosstalk |
| Q38921294 | Atorvastatin Protects NSC-34 Motor Neurons Against Oxidative Stress by Activating PI3K, ERK and Free Radical Scavenging |
| Q37107226 | Berberine induces dedifferentiation by actin cytoskeleton reorganization via phosphoinositide 3-kinase/Akt and p38 kinase pathways in rabbit articular chondrocytes |
| Q35755996 | Biological evaluation and docking studies of recently identified inhibitors of phosphoinositide-3-kinases. |
| Q36125362 | Bone marrow-derived mesenchymal stem cells enhance autophagy via PI3K/AKT signalling to reduce the severity of ischaemia/reperfusion-induced lung injury |
| Q99635766 | Brain region-specific lipid alterations in the PLB4 hBACE1 knock-in mouse model of Alzheimer's disease |
| Q34036441 | CCR9 interactions support ovarian cancer cell survival and resistance to cisplatin-induced apoptosis in a PI3K-dependent and FAK-independent fashion |
| Q38154977 | Cancer development, progression, and therapy: an epigenetic overview. |
| Q24529910 | Characterization of G alpha 13-dependent plasma membrane recruitment of p115RhoGEF |
| Q42450915 | Characterization of the interface between normal and transformed epithelial cells |
| Q37146877 | Characterizing the developmental pathways TTF-1, NKX2-8, and PAX9 in lung cancer |
| Q24634360 | Clinical and translational studies of a phase II trial of the novel oral Akt inhibitor perifosine in relapsed or relapsed/refractory Waldenstrom's macroglobulinemia |
| Q27334694 | Computational analysis of the spatiotemporal coordination of polarized PI3K and Rac1 activities in micro-patterned live cells |
| Q39199680 | Control of the PI3K/Akt pathway by porcine reproductive and respiratory syndrome virus |
| Q37075023 | Critical roles of the PI3K/Akt signaling pathway in T cell development |
| Q34992033 | Cross-talk between STAT1 and PI3K/AKT signaling in HIV-1-induced blood-brain barrier dysfunction: role of CCR5 and implications for viral neuropathogenesis |
| Q24533405 | Crystal structure of the phosphatidylinositol 3,4-bisphosphate-binding pleckstrin homology (PH) domain of tandem PH-domain-containing protein 1 (TAPP1): molecular basis of lipid specificity |
| Q35075499 | Deactivation of phosphatidylinositol 3,4,5-trisphosphate/Akt signaling mediates neutrophil spontaneous death. |
| Q34075366 | Deciphering combinations of PI3K/AKT/mTOR pathway drugs augmenting anti-angiogenic efficacy in vivo |
| Q43479791 | Differential regulation of interleukin-12 p40 and p35 induction via Erk mitogen-activated protein kinase-dependent and -independent mechanisms and the implications for bioactive IL-12 and IL-23 responses |
| Q24813382 | Differential responses to doxorubicin-induced phosphorylation and activation of Akt in human breast cancer cells. |
| Q39952817 | Differential signaling pathways in angiotensin II- and epidermal growth factor-stimulated hepatic C9 cells. |
| Q42065090 | Distinct roles for isoforms of the catalytic subunit of class-IA PI3K in the regulation of behaviour of murine embryonic stem cells |
| Q42081736 | Dual targeting of the PI3K/Akt/mTOR pathway as an antitumor strategy in Waldenstrom macroglobulinemia. |
| Q30857092 | Dynamics of cytoskeletal proteins during Fcgamma receptor-mediated phagocytosis in macrophages |
| Q35942332 | E-cadherin adhesion activates c-Src signaling at cell-cell contacts |
| Q90679554 | Effect of combined treatment with a pan-PI3K inhibitor or an isoform-specific PI3K inhibitor and everolimus on cell proliferation in GH-secreting pituitary tumour in an experimental setting |
| Q35050306 | Effects of bone marrow-derived mesenchymal stem cells on the axonal outgrowth through activation of PI3K/AKT signaling in primary cortical neurons followed oxygen-glucose deprivation injury |
| Q92455127 | Emerging Role of l-Dopa Decarboxylase in Flaviviridae Virus Infections |
| Q36537288 | Endothelial progenitor cells and neural progenitor cells synergistically protect cerebral endothelial cells from Hypoxia/reoxygenation-induced injury via activating the PI3K/Akt pathway |
| Q42008988 | Epithelial mesenchymal transition: a new insight into the detection of circulating tumor cells |
| Q33243804 | Evidence from bioinformatics, expression and inhibition studies of phosphoinositide-3 kinase signalling in Giardia intestinalis |
| Q36230579 | Exosomal miRs in Lung Cancer: A Mathematical Model |
| Q42089202 | Expression and clinical significance of the phosphatidylinositol 3-kinase/protein kinase B signal transduction pathway in non-small cell lung carcinoma |
| Q89884088 | Fourier Transform Infrared Spectroscopy Monitoring of Dihydroartemisinin-Induced Growth Inhibition in Ovarian Cancer Cells and Normal Ovarian Surface Epithelial Cells |
| Q43280944 | Frequent alterations of the PI3K/AKT/mTOR pathways in hereditary nonpolyposis colorectal cancer |
| Q36168847 | G protein-coupled receptors and the modification of FcepsilonRI-mediated mast cell activation |
| Q38056832 | GS-1101: a delta-specific PI3K inhibitor in chronic lymphocytic leukemia |
| Q35740567 | Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species |
| Q27470314 | Hepatitis C Virus Stimulates the Expression of Cyclooxygenase-2 via Oxidative Stress: Role of Prostaglandin E2 in RNA Replication |
| Q30156101 | Heterologous SH3-p85beta inhibits influenza A virus replication |
| Q39164827 | How does Reelin signaling regulate the neuronal cytoskeleton during migration? |
| Q35772509 | IL-10 Protects Neurites in Oxygen-Glucose-Deprived Cortical Neurons through the PI3K/Akt Pathway |
| Q34597585 | ILK mediates the effects of strain on intestinal epithelial wound closure |
| Q36212505 | Identification of Oxidized Phosphatidylinositols Present in OxLDL and Human Atherosclerotic Plaque |
| Q37583378 | Identification of a promising PI3K inhibitor for the treatment of multiple myeloma through the structural optimization |
| Q41837945 | IgA Fc receptor (FcalphaR) cross-linking recruits tyrosine kinases, phosphoinositide kinases and serine/threonine kinases to glycolipid rafts |
| Q24302191 | Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling |
| Q64251661 | Influenza Virus Infections and Cellular Kinases |
| Q40325777 | Inositol 1,3,4,5-tetrakisphosphate negatively regulates phosphatidylinositol-3,4,5- trisphosphate signaling in neutrophils |
| Q36742620 | Insulin signaling pathways and cardiac growth |
| Q36711111 | Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells |
| Q30365903 | Kisspeptin cell-specific PI3K signaling regulates hypothalamic kisspeptin expression and participates in the regulation of female fertility. |
| Q39521814 | Knockdown of Akt sensitizes osteosarcoma cells to apoptosis induced by cisplatin treatment |
| Q38703317 | Leptin enhances NR2B-mediated N-methyl-D-aspartate responses via a mitogen-activated protein kinase-dependent process in cerebellar granule cells |
| Q39912925 | M1 protein triggers a phosphoinositide cascade for group A Streptococcus invasion of epithelial cells. |
| Q38172352 | Make yourself at home: viral hijacking of the PI3K/Akt signaling pathway |
| Q46531919 | Mechanisms associated with Acanthamoeba castellanii (T4) phagocytosis |
| Q36000472 | Mesenchymal and stemness circulating tumor cells in early breast cancer diagnosis |
| Q37828371 | Metabolism, migration and memory in cytotoxic T cells |
| Q34521923 | Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity |
| Q36980988 | Microvascular endothelial cells-derived microvesicles imply in ischemic stroke by modulating astrocyte and blood brain barrier function and cerebral blood flow. |
| Q38313393 | Molecular control of PtdIns(3,4,5)P3 signaling in neutrophils |
| Q27006068 | Molecular pathways: targeting phosphoinositide 3-kinase p110-delta in chronic lymphocytic leukemia |
| Q43002589 | Monitoring of apoptosis of HL60 cells by Fourier-transform infrared spectroscopy |
| Q24338593 | NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons |
| Q37105052 | Neuron-NG2 cell synapses: novel functions for regulating NG2 cell proliferation and differentiation |
| Q51615949 | Neuroprotective Effects of Acetyl-L-Carnitine Against Oxygen-Glucose Deprivation-Induced Neural Stem Cell Death. |
| Q36741846 | Neuroprotective and antioxidant activities of bamboo salt soy sauce against H2O2-induced oxidative stress in rat cortical neurons |
| Q36096852 | Neurotrophin-dependent dendritic filopodial motility: a convergence on PI3K signaling |
| Q33733933 | Neutrophil spontaneous death is mediated by down-regulation of autocrine signaling through GPCR, PI3Kgamma, ROS, and actin. |
| Q93052971 | Nicotiana benthamiana phosphatidylinositol 4-kinase type II regulates chilli leaf curl virus pathogenesis |
| Q33683449 | Non-peptidic substrate-mimetic inhibitors of Akt as potential anti-cancer agents |
| Q55418695 | Novel Phospholipid Signature of Depressive Symptoms in Patients With Coronary Artery Disease. |
| Q33694968 | Novel osmotin attenuates glutamate-induced synaptic dysfunction and neurodegeneration via the JNK/PI3K/Akt pathway in postnatal rat brain |
| Q33598550 | Oridonin induces G2/M cell cycle arrest and apoptosis via the PI3K/Akt signaling pathway in hormone-independent prostate cancer cells |
| Q28564711 | P2X7 receptors stimulate AKT phosphorylation in astrocytes |
| Q38175868 | PI3-kinase inhibitors in chronic lymphocytic leukemia |
| Q30480771 | PI3K and Erk MAPK mediate ErbB signaling in Xenopus gastrulation |
| Q24304468 | PI3K is negatively regulated by PIK3IP1, a novel p110 interacting protein |
| Q21131282 | PI3K: An Attractive Candidate for the Central Integration of Metabolism and Reproduction |
| Q90379431 | PI3Kinase-p110δ Overexpression Impairs Dendritic Morphogenesis and Increases Dendritic Spine Density |
| Q34047720 | PIP3 inhibition of RGS protein and its reversal by Ca2+/calmodulin mediate voltage-dependent control of the G protein cycle in a cardiac K+ channel |
| Q89983732 | PROM2 promotes gemcitabine chemoresistance via activating the Akt signaling pathway in pancreatic cancer |
| Q24528114 | PTEN function: how normal cells control it and tumour cells lose it |
| Q33711127 | Phase II trial of the oral mammalian target of rapamycin inhibitor everolimus in relapsed or refractory Waldenstrom macroglobulinemia |
| Q28203054 | Phosphatidylinositol 3-Kinase Regulates the Induction of Long-Term Potentiation through Extracellular Signal-Related Kinase-Independent Mechanisms |
| Q34184717 | Phosphatidylinositol 3-kinase-δ inhibitor CAL-101 shows promising preclinical activity in chronic lymphocytic leukemia by antagonizing intrinsic and extrinsic cellular survival signals |
| Q41484781 | Phosphatidylinositol 3‐kinase‐δ up‐regulates L‐type Ca2+ currents and increases vascular contractility in a mouse model of type 1 diabetes |
| Q36323102 | Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1. |
| Q44343456 | Phosphoinositide 3-kinase cascade facilitates mu-opioid desensitization in sensory neurons by altering G-protein-effector interactions. |
| Q35991491 | Phosphoinositide lipid second messengers: new paradigms for transepithelial signal transduction |
| Q57475819 | Platelet-rich plasma as a potential therapeutic approach against lead nitrate- and/or gamma radiation-induced hepatotoxicity |
| Q35067637 | Pretreatment with phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor SF1670 augments the efficacy of granulocyte transfusion in a clinically relevant mouse model |
| Q64233033 | Pristimerin induces apoptosis of oral squamous cell carcinoma cells via G phase arrest and MAPK/Erk1/2 and Akt signaling inhibition |
| Q27347612 | Ptenb mediates gastrulation cell movements via Cdc42/AKT1 in zebrafish |
| Q35849981 | Puerarin attenuates glucocorticoid-induced apoptosis of hFOB1.19 cells through the JNK- and Akt-mediated mitochondrial apoptotic pathways |
| Q56999583 | Quantitative immunodetection of key elements of polyphosphoinositide signal transduction in osteoblasts from arthritic patients shows a direct correlation with cell proliferation |
| Q26753142 | ROS and ROS-Mediated Cellular Signaling |
| Q28388989 | Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling |
| Q36266420 | Redox regulation of PI 3-kinase signalling via inactivation of PTEN |
| Q37943329 | Reelin modulates cytoskeletal organization by regulating Rho GTPases |
| Q30530108 | Reelin signals through apolipoprotein E receptor 2 and Cdc42 to increase growth cone motility and filopodia formation |
| Q33527391 | Regulation of gene expression by PI3K in mouse growth plate chondrocytes |
| Q35968234 | Regulation of inducible nitric oxide synthase gene in glial cells. |
| Q28483244 | Resveratrol inhibits LPS-induced MAPKs activation via activation of the phosphatidylinositol 3-kinase pathway in murine RAW 264.7 macrophage cells |
| Q24794042 | Retroviral expression of a kinase-defective IGF-I receptor suppresses growth and causes apoptosis of CHO and U87 cells in-vivo |
| Q47246356 | Salidroside inhibits steroid-induced avascular necrosis of the femoral head via the PI3K/Akt signaling pathway: In vitro and in vivo studies. |
| Q36410968 | Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein |
| Q35085522 | Signal transduction events regulating integrin function and T cell migration: new functions and complexity |
| Q52717934 | Signaling and Function of Interleukin-2 in T Lymphocytes. |
| Q40219853 | Signaling pathways mediating manganese-induced toxicity in human glioblastoma cells (u87). |
| Q55386096 | Small Rho GTPases and the Effector VipA Mediate the Invasion of Epithelial Cells by Filamentous Legionella pneumophila. |
| Q34648790 | Sodium antimony gluconate induces generation of reactive oxygen species and nitric oxide via phosphoinositide 3-kinase and mitogen-activated protein kinase activation in Leishmania donovani-infected macrophages |
| Q37360176 | Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients |
| Q27472897 | Subversion of Cell Signaling Pathways by Hepatitis C Virus Nonstructural 5A Protein via Interaction with Grb2 and P85 Phosphatidylinositol 3-Kinase |
| Q35791508 | Systematic investigation into the role of intermittent high glucose in pancreatic beta-cells |
| Q59748443 | T-cell antigen receptor signal transduction |
| Q64081459 | TGF‑β1 promotes the osteoinduction of human osteoblasts via the PI3K/AKT/mTOR/S6K1 signalling pathway |
| Q37950586 | Targeting the bone marrow in Waldenstrom macroglobulinemia. |
| Q28244041 | The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia |
| Q33327777 | The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation |
| Q24533547 | The Phox homology (PX) domain, a new player in phosphoinositide signalling |
| Q38095959 | The bone marrow microenvironment in waldenstrom macroglobulinemia. |
| Q37022144 | The epidermal growth factor receptor regulates cofilin activity and promotes transmissible gastroenteritis virus entry into intestinal epithelial cells |
| Q39700008 | The interferon-gamma-induced murine guanylate-binding protein-2 inhibits rac activation during cell spreading on fibronectin and after platelet-derived growth factor treatment: role for phosphatidylinositol 3-kinase |
| Q33564954 | The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathway |
| Q33704281 | The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling |
| Q36815262 | The proteasome inhibitor carfilzomib functions independently of p53 to induce cytotoxicity and an atypical NF-κB response in chronic lymphocytic leukemia cells |
| Q35915458 | The role of phosphoinositide 3-kinase signaling in intestinal inflammation |
| Q35067253 | The role of prolactin in mammary carcinoma |
| Q43590742 | The α-isoform of class II phosphoinositide 3-kinase is necessary for the activation of ERK but not Akt/PKB. |
| Q36325885 | Tissue and time specific expression pattern of interferon regulated genes in the chicken. |
| Q24797020 | Topographical expression of class IA and class II phosphoinositide 3-kinase enzymes in normal human tissues is consistent with a role in differentiation |
| Q36099849 | Transcriptome and gene expression analysis of DHA producer Aurantiochytrium under low temperature conditions |
| Q34286691 | Transduction of growth or mitogenic signals into translational activation of TOP mRNAs is fully reliant on the phosphatidylinositol 3-kinase-mediated pathway but requires neither S6K1 nor rpS6 phosphorylation |
| Q39612731 | Translational up-regulation and high-level protein expression from plasmid vectors by mTOR activation via different pathways in PC3 and 293T cells |
| Q28564173 | Tyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signaling |
| Q30591155 | Whole genome association study identifies regions of the bovine genome and biological pathways involved in carcass trait performance in Holstein-Friesian cattle |
| Q33903097 | c-erbB2-induced disruption of matrix adhesion and morphogenesis reveals a novel role for protein kinase B as a negative regulator of alpha(2)beta(1) integrin function |
| Q58698118 | mTORC1 Prevents Epithelial Damage During Inflammation and Inhibits Colitis-Associated Colorectal Cancer Development |
| Q90677872 | p75NTR-/- mice exhibit an alveolar bone loss phenotype and inhibited PI3K/Akt/β-catenin pathway |
| Q54332608 | p85 protein expression is associated with poor survival in HER2-positive patients with advanced breast cancer treated with trastuzumab. |
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