IL-10 Protects Neurites in Oxygen-Glucose-Deprived Cortical Neurons through the PI3K/Akt Pathway

scientific article published on 14 September 2015

IL-10 Protects Neurites in Oxygen-Glucose-Deprived Cortical Neurons through the PI3K/Akt Pathway is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2015PLoSO..1036959L
P356DOI10.1371/JOURNAL.PONE.0136959
P932PMC publication ID4569574
P698PubMed publication ID26366999
P5875ResearchGate publication ID281782298

P2093author name stringYong Liu
Ronghua Chen
Nan Liu
Hongbin Chen
Yi Tan
Wei Lin
Houwei Du
Jianhao Chen
Longzai Lin
Tin Li
Yixian Zhang
Yongping Zeng
P2860cites workInterleukin-10 modulates neuronal threshold of vulnerability to ischaemic damageQ74187418
The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-kapp B signalingQ28571207
A p53-CBP/p300 transcription module is required for GAP-43 expression, axon outgrowth, and regenerationQ28579945
Morphological alteration and reduction of MAP2-immunoreactivity in pyramidal neurons of cerebral cortex in a rat model of focal cortical compressionQ28582954
Activation of Akt/GSK-3beta signaling pathway is involved in intermedin(1-53) protection against myocardial apoptosis induced by ischemia/reperfusionQ33487246
Phosphoinositide 3-kinase signalling pathwaysQ33940898
Activation of ERK1/2 and PI3K/Akt by IGF-1 on GAP-43 expression in DRG neurons with excitotoxicity induced by glutamate in vitroQ33984849
Moderate traumatic brain injury causes acute dendritic and synaptic degeneration in the hippocampal dentate gyrusQ34023694
Caspases: key players in programmed cell deathQ34103392
Sulforaphane protects primary cultures of cortical neurons against injury induced by oxygen-glucose deprivation/reoxygenation via antiapoptosisQ34440320
Erythropoietin prevents PC12 cells from beta-amyloid-induced apoptosis via PI3K⁄Akt pathwayQ34501237
Retracted: Novel Mechanism of Inhibition of Dendritic Cells Maturation by Mesenchymal Stem Cells via Interleukin-10 and the JAK1/STAT3 Signaling PathwayQ34576628
Effects of bone marrow-derived mesenchymal stem cells on the axonal outgrowth through activation of PI3K/AKT signaling in primary cortical neurons followed oxygen-glucose deprivation injuryQ35050306
NF-kappaB in the survival and plasticity of neuronsQ36269312
Delayed administration of a PTEN inhibitor BPV improves functional recovery after experimental strokeQ36951450
Interleukin-10 provides direct trophic support to neurons.Q37331339
Inflammation, plasticity and real-time imaging after cerebral ischemiaQ37395869
Involvement of Akt in neurite outgrowthQ37510693
Expression of IL-10 and TNF-alpha in rats with cerebral infarction after transplantation with mesenchymal stem cellsQ37729395
IL-10 plays a pivotal role in anti-inflammatory effects of resveratrol in activated microglia cellsQ38921416
Salvianic acid A protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity.Q40463919
Interleukin-10 receptor signaling through STAT-3 regulates the apoptosis of retinal ganglion cells in response to stressQ40613314
Degeneration of axotomized projection neurons in the rat dLGN: temporal progression of events and their mitigation by a single administration of FGF2.Q41472225
Diversity and fluctuation of spine morphology in CA1 pyramidal neurons after transient global ischemiaQ42440460
Apocynum venetum leaf extract protects rat cortical neurons from injury induced by oxygen and glucose deprivation in vitroQ42870055
Neuroprotective effects of water-soluble Ganoderma lucidum polysaccharides on cerebral ischemic injury in ratsQ42987727
IL-10 directly protects cortical neurons by activating PI-3 kinase and STAT-3 pathwaysQ44189986
Association of Gap-43 (neuromodulin) with microtubule-associated protein MAP-2 in neuronal cellsQ44318472
Manipulation of gonadal hormones in neonatal rats alters the morphological response of cortical neurons to brain injury in adulthoodQ44412236
Distribution of GAP-43, beta-III tubulin and F-actin in developing and regenerating axons and their growth cones in vitro, following neurotrophin treatmentQ44814944
The role of HSPA12B in regulating neuronal apoptosisQ45853650
Postischemic gene transfer of interleukin-10 protects against both focal and global brain ischemiaQ45881278
Oxygen and glucose deprivation induces major dysfunction in the somatosensory cortex of the newborn rat.Q46785571
Distribution of phosphorylated GAP-43 (neuromodulin) in growth cones directly reflects growth cone behaviorQ47988645
Bone marrow stromal cells mediate protection through stimulation of PI3-K/Akt and MAPK signaling in neurons.Q48393208
IL-10 reduces rat brain injury following focal strokeQ48401527
Axotomy-induced neuronal death and reactive astrogliosis in the lateral geniculate nucleus following a lesion of the visual cortex in the rat.Q48505155
Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke.Q48788015
Effects of treadmill exercise on the expression of netrin-1 and its receptors in rat brain after cerebral ischemiaQ48960603
Inhibition of prostaglandin E2 EP3 receptors improves stroke injury via anti-inflammatory and anti-apoptotic mechanisms.Q48974744
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectneuriteQ1534415
P304page(s)e0136959
P577publication date2015-09-14
P1433published inPLOS OneQ564954
P1476titleIL-10 Protects Neurites in Oxygen-Glucose-Deprived Cortical Neurons through the PI3K/Akt Pathway
P478volume10

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cites work (P2860)
Q38740395Conditioned medium of periodontal ligament mesenchymal stem cells exert anti-inflammatory effects in lipopolysaccharide-activated mouse motoneurons
Q91691956IL-10 produces a dual effect on OGD-induced neuronal apoptosis of cultured cortical neurons via the NF-κB pathway
Q46124483Interleukin-10 Attenuates Hypochlorous Acid-Mediated Cytotoxicity to HEI-OC1 Cochlear Cells
Q35936981MLIF Alleviates SH-SY5Y Neuroblastoma Injury Induced by Oxygen-Glucose Deprivation by Targeting Eukaryotic Translation Elongation Factor 1A2.
Q33887223Mesenchymal Stem Cells Overexpressing Interleukin-10 Promote Neuroprotection in Experimental Acute Ischemic Stroke
Q36582668Naoxintong Protects Primary Neurons from Oxygen-Glucose Deprivation/Reoxygenation Induced Injury through PI3K-Akt Signaling Pathway.
Q47374262Netrin-1 Prevents Rat Primary Cortical Neurons from Apoptosis via the DCC/ERK Pathway
Q51471496Neurotoxicity of Methylmercury in Isolated Astrocytes and Neurons: the Cytoskeleton as a Main Target.
Q92514397Transplantation of mesenchymal stem cells overexpressing interleukin-10 induces autophagy response and promotes neuroprotection in a rat model of TBI

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