| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Brian J DeBosch | |
| Anthony J Muslin | |||
| P2860 | cites work | The control of growth | Q79247972 |
| The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110alpha) pathway | Q79248092 | ||
| Effects of growth hormone on exercise capacity and cardiopulmonary performance in patients with chronic heart failure | Q80796298 | ||
| Akt1 is required for physiological cardiac growth | Q83195147 | ||
| Gestational diabetes mellitus outcome in 394 patients | Q83211886 | ||
| CAP defines a second signalling pathway required for insulin-stimulated glucose transport | Q24290287 | ||
| Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10 | Q24291135 | ||
| The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
| Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity | Q24322837 | ||
| APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes | Q24537413 | ||
| Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart | Q24562618 | ||
| Signaling by distinct classes of phosphoinositide 3-kinases | Q28139034 | ||
| The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp | Q28269747 | ||
| The COOH-terminal tyrosine phosphorylation sites on IRS-1 bind SHP-2 and negatively regulate insulin signaling | Q28284128 | ||
| Bone marrow-specific Cap gene deletion protects against high-fat diet-induced insulin resistance | Q28292442 | ||
| Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis | Q28343294 | ||
| Increased Insulin Sensitivity and Hypoinsulinemia in APS Knockout Mice | Q28507200 | ||
| Role for Akt3/protein kinase Bgamma in attainment of normal brain size | Q28509294 | ||
| Hyperinsulinemia: effect on cardiac mass/function, angiotensin II receptor expression, and insulin signaling pathways | Q28565051 | ||
| Molecular cloning of rat SH2-containing inositol phosphatase 2 (SHIP2) and its role in the regulation of insulin signaling | Q28581883 | ||
| The lipid phosphatase SHIP2 controls insulin sensitivity | Q28584843 | ||
| Effects of constitutive overexpression of insulin-like growth factor-1 on the mechanical characteristics and molecular properties of ventricular myocytes | Q74405488 | ||
| Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity | Q28590308 | ||
| Insulin signalling | Q28611467 | ||
| Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes | Q28615460 | ||
| The insulin signaling system | Q28615921 | ||
| Cardiovascular and craniofacial defects in Crk-null mice | Q30159699 | ||
| Mutant mice lacking Crk-II caused by the gene trap insertional mutagenesis: Crk-II is not essential for embryonic development | Q30175280 | ||
| Atypical protein kinase C (PKCzeta/lambda) is a convergent downstream target of the insulin-stimulated phosphatidylinositol 3-kinase and TC10 signaling pathways | Q30443468 | ||
| Improvements in systemic metabolism, anthropometrics, and left ventricular geometry 3 months after bariatric surgery | Q30499208 | ||
| Growth hormone and the heart | Q32026861 | ||
| Growth hormone therapy for heart failure: swimming against the stream | Q33738009 | ||
| Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity | Q33880454 | ||
| Phosphoinositide 3-kinase signalling pathways | Q33940898 | ||
| Effects of growth hormone and insulin-like growth factor I in experimental heart failure | Q34035032 | ||
| Class IA phosphoinositide 3-kinase regulates heart size and physiological cardiac hypertrophy | Q34097448 | ||
| Insulin receptor substrate-4 is expressed in muscle tissue without acting as a substrate for the insulin receptor | Q34183944 | ||
| Outcome success in obesity | Q34438273 | ||
| Effect of treatment of gestational diabetes mellitus on pregnancy outcomes | Q34558501 | ||
| Signalling through IGF-I and insulin receptors: where is the specificity? | Q34783548 | ||
| Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression | Q34789045 | ||
| Deletion of ribosomal S6 kinases does not attenuate pathological, physiological, or insulin-like growth factor 1 receptor-phosphoinositide 3-kinase-induced cardiac hypertrophy | Q35126646 | ||
| Clinical course of genetic diseases of the insulin receptor (type A and Rabson-Mendenhall syndromes): a 30-year prospective | Q35825537 | ||
| Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes | Q35879528 | ||
| Insulin signaling in heart muscle: lessons from genetically engineered mouse models. | Q35940001 | ||
| Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia | Q36246003 | ||
| The conserved phosphoinositide 3-kinase pathway determines heart size in mice | Q36246110 | ||
| Insulin signaling and the regulation of glucose transport. | Q36321818 | ||
| Phosphoinositide 3-kinase(p110α) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy | Q36350066 | ||
| Diabetic cardiomyopathy: the search for a unifying hypothesis | Q36423632 | ||
| Lipid phosphatases as drug discovery targets for type 2 diabetes. | Q36438742 | ||
| PTEN and SHIP2 phosphoinositide phosphatases as negative regulators of insulin signalling. | Q36576538 | ||
| Systems biology of AGC kinases in fungi | Q36593112 | ||
| The role of insulin-like growth factor binding proteins. | Q36626462 | ||
| Cardiac abnormalities in young women with anorexia nervosa | Q36812773 | ||
| Cardiovascular actions of insulin | Q36831533 | ||
| Long-term cardiovascular effects of growth hormone treatment in GH-deficient adults. Preliminary data in a small group of patients | Q36835965 | ||
| Pharmacologic therapy in growth hormone disorders and the heart | Q36855413 | ||
| Diabetic cardiomyopathy revisited | Q36860318 | ||
| IGF-I treatment of insulin resistance | Q36929224 | ||
| Akt2 regulates cardiac metabolism and cardiomyocyte survival | Q37297743 | ||
| c-Cbl-deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action | Q37591960 | ||
| Genetic ablation of the c-Cbl ubiquitin ligase domain results in increased energy expenditure and improved insulin action | Q38307291 | ||
| Effect of weight loss on the ECG of normotensive morbidly obese patients | Q38494471 | ||
| Premature mortality due to cardiovascular disease in hypopituitarism | Q38516015 | ||
| Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways | Q39750571 | ||
| Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant | Q40256910 | ||
| Differential roles of the insulin and insulin-like growth factor-I (IGF-I) receptors in response to insulin and IGF-I. | Q40537000 | ||
| The insulin receptor: structure, function, and signaling | Q40732164 | ||
| Using structure to define the function of phosphoinositide 3-kinase family members | Q41554112 | ||
| Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function | Q41817667 | ||
| Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and immunoblotting | Q42139574 | ||
| Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure. | Q42447268 | ||
| Deficiency of Cbl-b gene enhances infiltration and activation of macrophages in adipose tissue and causes peripheral insulin resistance in mice | Q42826978 | ||
| Akt signaling mediates postnatal heart growth in response to insulin and nutritional status | Q44090717 | ||
| Relationship of Insulin Sensitivity and Left Ventricular Mass in Uncomplicated Obesity | Q44400043 | ||
| Akt3 overexpression in the heart results in progression from adaptive to maladaptive hypertrophy | Q45255903 | ||
| Effect of growth on variability of left ventricular mass: assessment of allometric signals in adults and children and their capacity to predict cardiovascular risk | Q45272071 | ||
| The role of hypertrophy and growth factors in heart failure. | Q45964307 | ||
| Cardiovascular effects of insulin-like growth factor-1 and growth hormone in chronic left ventricular failure in the rat. | Q46114667 | ||
| Effects of growth hormone and IGF-I on cardiac hypertrophy and gene expression in mice. | Q46183533 | ||
| Differential role of SH2-B and APS in regulating energy and glucose homeostasis | Q46925721 | ||
| Increased protein synthesis after acute IGF-I or insulin infusion is localized to muscle in mice | Q47747685 | ||
| Associations of insulin levels with left ventricular structure and function in American Indians: the strong heart study. | Q51543326 | ||
| Reduced left ventricular mass after treatment of obese patients with sibutramine: An echocardiographic multicentre study. | Q51781829 | ||
| Insulin receptor substrate 3 is not essential for growth or glucose homeostasis. | Q52535322 | ||
| Mice lacking insulin receptor substrate 4 exhibit mild defects in growth, reproduction, and glucose homeostasis. | Q52537778 | ||
| Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance. | Q52540333 | ||
| Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia. | Q52541535 | ||
| PI3K(p110alpha) inhibitors as anti-cancer agents: minding the heart. | Q53561943 | ||
| Insulin resistance and cardiac mass: the end of the beginning? | Q53934179 | ||
| New insulin-like proteins with atypical disulfide bond pattern characterized in Caenorhabditis elegans by comparative sequence analysis and homology modeling. | Q54673518 | ||
| Sudden, unexpected death in avid dieters using the liquid-protein-modified-fast diet. Observations in 17 patients and the role of the prolonged QT interval | Q59444437 | ||
| Mutant insulin receptors in syndromes of insulin resistance | Q61908582 | ||
| Insulin-like growth factor I receptor beta-subunit heterogeneity. Evidence for hybrid tetramers composed of insulin-like growth factor I and insulin receptor heterodimers | Q69353255 | ||
| Growth hormone treatment in growth hormone-deficient adults. II. Effects on exercise performance | Q70143979 | ||
| Cholinergic but not serotonergic mediation of exercise-induced growth hormone secretion | Q70144003 | ||
| Cardiovascular effects of growth hormone replacement therapy in hypopituitary adults | Q72414192 | ||
| Cardiac performance and mass in adults with hypopituitarism: effects of one year of growth hormone treatment | Q72536629 | ||
| Postnatal growth responses to insulin-like growth factor I in insulin receptor substrate-1-deficient mice | Q73222328 | ||
| Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis | Q73504931 | ||
| Growth hormone prolongs survival in experimental postinfarction heart failure | Q73562085 | ||
| P433 | issue | 5 | |
| P304 | page(s) | 855-864 | |
| P577 | publication date | 2008-03-19 | |
| P1433 | published in | Journal of Molecular and Cellular Cardiology | Q2061932 |
| P1476 | title | Insulin signaling pathways and cardiac growth | |
| P478 | volume | 44 |
| Q48232901 | 3D aggregate culture improves metabolic maturation of human pluripotent stem cell derived cardiomyocytes |
| Q42159077 | AKIP1, a cardiac hypertrophy induced protein that stimulates cardiomyocyte growth via the Akt pathway |
| Q37393585 | Cardioprotective growth factors |
| Q86664257 | Hypertrophic cardiomyopathy in Donohue syndrome |
| Q89966101 | Identification of Biological Pathways Contributing to Marbling in Skeletal Muscle to Improve Beef Cattle Breeding |
| Q43582859 | Insulin suppresses IKs (KCNQ1/KCNE1) currents, which require β-subunit KCNE1. |
| Q27324739 | Let-7 family of microRNA is required for maturation and adult-like metabolism in stem cell-derived cardiomyocytes |
| Q42765156 | New insights into cardiac aging |
| Q90447463 | Oxidative Stress in Radiation-Induced Cardiotoxicity |
| Q92874180 | Predictors of early cardiac changes in patients with type 1 diabetes mellitus: An echocardiography-based study |
| Q38525084 | Priming with ligands secreted by human stromal progenitor cells promotes grafts of cardiac stem/progenitor cells after myocardial infarction |
| Q37102358 | Prolonged exposure to GH impairs insulin signaling in the heart. |
| Q38217249 | Protein-protein interactions and genetic diseases: The interactome |
| Q27025162 | Regulation of cardiac autophagy by insulin-like growth factor 1 |
| Q30983909 | Regulation of the cardiomyocyte transcriptome vs translatome by endothelin-1 and insulin: translational regulation of 5' terminal oligopyrimidine tract (TOP) mRNAs by insulin |
| Q54977881 | Selective Insulin-like Growth Factor Resistance Associated with Heart Hemorrhages and Poor Prognosis in a Novel Preclinical Model of the Hematopoietic Acute Radiation Syndrome. |
| Q97549764 | Short high-fat diet interferes with the physiological maturation of the late adolescent mouse heart |
| Q61912834 | The Multiple Actions of the Insulin-Like Growth Factor-I Signaling in the Myocardium |
| Q37793527 | What Causes a Broken Heart—Molecular Insights into Heart Failure |
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