| scholarly article | Q13442814 |
| P50 | author | Christopher J Gamper | Q57016123 |
| P2093 | author name string | Jonathan D Powell | |
| P2860 | cites work | Role of the phosphoinositide 3-kinase p110delta in generation of type 2 cytokine responses and allergic airway inflammation | Q79605222 |
| Activation of mTORC2 by association with the ribosome | Q24294876 | ||
| Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex | Q24295120 | ||
| mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1) | Q24324148 | ||
| Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1 | Q24336199 | ||
| Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX. | Q24514761 | ||
| Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1 | Q24531380 | ||
| mTOR signaling in growth control and disease | Q24634174 | ||
| Role of diacylglycerol kinase alpha in the attenuation of receptor signaling | Q24683951 | ||
| Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change | Q27642001 | ||
| PI3K in lymphocyte development, differentiation and activation | Q28187880 | ||
| A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation | Q28202234 | ||
| Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice | Q28215433 | ||
| SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity | Q28262782 | ||
| Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction | Q28292732 | ||
| Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB | Q28306356 | ||
| The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C | Q28587901 | ||
| The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3 | Q28610410 | ||
| Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B | Q28646376 | ||
| Follicular helper CD4 T cells (TFH) | Q29615063 | ||
| Multiple site acetylation of Rictor stimulates mammalian target of rapamycin complex 2 (mTORC2)-dependent phosphorylation of Akt protein | Q30423008 | ||
| Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells | Q33742099 | ||
| Anergic T cells are metabolically anergic | Q33908515 | ||
| Phosphoinositide 3-kinase signalling pathways | Q33940898 | ||
| Transcriptional mechanisms underlying lymphocyte tolerance. | Q34135663 | ||
| Genetic or pharmaceutical blockade of phosphoinositide 3-kinase p110δ prevents chronic rejection of heart allografts | Q34221228 | ||
| Protein kinase B (Akt) regulation and function in T lymphocytes | Q34555105 | ||
| The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2. | Q34801853 | ||
| PTEN inhibits IL-2 receptor-mediated expansion of CD4+ CD25+ Tregs | Q34997285 | ||
| Sjögren's syndrome-like disease in mice with T cells lacking class 1A phosphoinositide-3-kinase | Q35130783 | ||
| T-cell function is partially maintained in the absence of class IA phosphoinositide 3-kinase signaling. | Q35750980 | ||
| PI3Ks in lymphocyte signaling and development | Q35843746 | ||
| Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002. | Q35909879 | ||
| Forkhead-box transcription factors and their role in the immune system | Q35934174 | ||
| Phosphoinositide 3-kinase gamma participates in T cell receptor-induced T cell activation. | Q36229227 | ||
| Th17: an effector CD4 T cell lineage with regulatory T cell ties | Q36510274 | ||
| PI3K signalling in B- and T-lymphocytes: new developments and therapeutic advances | Q36516932 | ||
| T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR. | Q36693820 | ||
| Allogeneic hematopoietic stem-cell transplantation for sickle cell disease | Q36769277 | ||
| The p110gamma isoform of phosphatidylinositol 3-kinase regulates migration of effector CD4 T lymphocytes into peripheral inflammatory sites. | Q36838574 | ||
| Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activation | Q37358144 | ||
| Phosphoinositide 3-kinase and the mammalian target of rapamycin pathways control T cell migration | Q37690383 | ||
| Mammalian target of rapamycin integrates diverse inputs to guide the outcome of antigen recognition in T cells | Q38007403 | ||
| Egr-2 and Egr-3 are negative regulators of T cell activation. | Q38327900 | ||
| Immunotherapy with PI3K inhibitor and Toll-like receptor agonist induces IFN-γ+IL-17+ polyfunctional T cells that mediate rejection of murine tumors. | Q39430127 | ||
| T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-alpha | Q40222415 | ||
| Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration | Q40900789 | ||
| PI3K p110delta regulates T-cell cytokine production during primary and secondary immune responses in mice and humans | Q41367429 | ||
| Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways | Q42099912 | ||
| Pten loss in CD4 T cells enhances their helper function but does not lead to autoimmunity or lymphoma. | Q42206056 | ||
| De novo induction of antigen-specific CD4+CD25+Foxp3+ regulatory T cells in vivo following systemic antigen administration accompanied by blockade of mTOR. | Q42524659 | ||
| The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment | Q42593305 | ||
| MAPK, phosphatidylinositol 3-kinase, and mammalian target of rapamycin pathways converge at the level of ribosomal protein S6 phosphorylation to control metabolic signaling in CD8 T cells | Q43241045 | ||
| Enhanced T cell proliferation in mice lacking the p85beta subunit of phosphoinositide 3-kinase | Q43842315 | ||
| Inhibition of T and B lymphocyte proliferation by rapamycin | Q43923204 | ||
| Selective regulation of CD8 effector T cell migration by the p110 gamma isoform of phosphatidylinositol 3-kinase | Q45213203 | ||
| Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells. | Q45299244 | ||
| Low-dose radiation plus rapamycin promotes long-term bone marrow chimerism | Q46863629 | ||
| CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer. | Q46897630 | ||
| IFN-gamma determines distinct clinical outcomes in autoimmune encephalomyelitis | Q49129042 | ||
| PI3Kδ drives the pathogenesis of experimental autoimmune encephalomyelitis by inhibiting effector T cell apoptosis and promoting Th17 differentiation. | Q51017092 | ||
| Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells. | Q51908453 | ||
| Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase. | Q52533403 | ||
| Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha. | Q52533405 | ||
| PI3K-Akt-mTORC1-S6K1/2 axis controls Th17 differentiation by regulating Gfi1 expression and nuclear translocation of RORγ. | Q54494791 | ||
| The p110delta isoform of phosphatidylinositol 3-kinase controls susceptibility to Leishmania major by regulating expansion and tissue homing of regulatory T cells. | Q54733077 | ||
| Cutting edge: the phosphoinositide 3-kinase p110 delta is critical for the function of CD4+CD25+Foxp3+ regulatory T cells | Q56901814 | ||
| Induction of alloantigen-specific T cell tolerance through the treatment of human T lymphocytes with wortmannin | Q56908516 | ||
| T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance | Q57185252 | ||
| Inhibition of CD28-mediated T cell costimulation by the phosphoinositide 3-kinase inhibitor wortmannin | Q62733752 | ||
| Inhibition of cell cycle progression by rapamycin induces T cell clonal anergy even in the presence of costimulation | Q74595877 | ||
| The p110delta isoform of phosphoinositide 3-kinase controls clonal expansion and differentiation of Th cells | Q79174363 | ||
| P304 | page(s) | 312 | |
| P577 | publication date | 2012-10-09 | |
| P1433 | published in | Frontiers in Immunology | Q27723748 |
| P1476 | title | All PI3Kinase signaling is not mTOR: dissecting mTOR-dependent and independent signaling pathways in T cells | |
| P478 | volume | 3 |
| Q64067656 | Differential Cytokine Utilization and Tissue Tropism Results in Distinct Repopulation Kinetics of Naïve vs. Memory T Cells in Mice |
| Q37444593 | Distinct signaling pathways regulate TLR2 co-stimulatory function in human T cells |
| Q36866169 | Early in vivo signaling profiles in MUC1-specific CD4(+) T cells responding to two different MUC1-targeting vaccines in two different microenvironments |
| Q45389799 | Epigallocatechin-3-gallate (EGCG) up-regulates miR-15b expression thus attenuating store operated calcium entry (SOCE) into murine CD4+ T cells and human leukaemic T cell lymphoblasts |
| Q37625317 | Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signaling |
| Q37590579 | Keeping It All Going-Complement Meets Metabolism |
| Q41046107 | Lipids Regulate Lck Protein Activity through Their Interactions with the Lck Src Homology 2 Domain |
| Q64075171 | NF-κB/mTOR/MYC Axis Drives PRMT5 Protein Induction After T Cell Activation via Transcriptional and Non-transcriptional Mechanisms |
| Q41993905 | Na+ influx via Orai1 inhibits intracellular ATP-induced mTORC2 signaling to disrupt CD4 T cell gene expression and differentiation |
| Q40217706 | Natural killer group 2D and CD28 receptors differentially activate mammalian/mechanistic target of rapamycin to alter murine effector CD8+ T-cell differentiation |
| Q47936526 | Novel combination strategies for enhancing efficacy of immune checkpoint inhibitors in the treatment of metastatic solid malignancies |
| Q42972198 | PI3K Signaling in B Cell and T Cell Biology. |
| Q45908531 | PI3K and Inhibitor of Apoptosis Proteins Modulate Gentamicin- Induced Hair Cell Death in the Zebrafish Lateral Line. |
| Q88446289 | Posttranscriptional regulation of T helper cell fate decisions |
| Q50355256 | Preclinical evaluation of the PI3K/Akt/mTOR pathway in animal models of multiple sclerosis |
| Q39198154 | Prospects for combining targeted and conventional cancer therapy with immunotherapy |
| Q33575261 | Reduction of HIV persistence following transplantation in HIV-infected kidney transplant recipients |
| Q35834072 | Regulation of mTOR Signaling by Semaphorin 3F-Neuropilin 2 Interactions In Vitro and In Vivo |
| Q36760689 | Role of PI3K-AKT-mTOR and Wnt Signaling Pathways in Transition of G1-S Phase of Cell Cycle in Cancer Cells. |
| Q54976588 | Targeting the class IA PI3K isoforms p110α/δ attenuates heart allograft rejection in mice by suppressing the CD4+ T lymphocyte response. |
| Q91750503 | The Sources of Essential Fatty Acids for Allergic and Cancer Patients; a Connection with Insight into Mammalian Target of Rapamycin: A Narrative Review |
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