Androgen-independent prostate cancer: potential role of androgen and ErbB receptor signal transduction crosstalk

scientific article

Androgen-independent prostate cancer: potential role of androgen and ErbB receptor signal transduction crosstalk is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S1476-5586(03)80001-5
P932PMC publication ID1502396
P698PubMed publication ID12659682

P50authorEl-Nasir LalaniQ63643363
P2093author name stringGordon Stamp
Jan Domin
Paul Abel
Soha Salama El Sheikh
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Repression of androgen receptor mediated transcription by the ErbB-3 binding protein, Ebp1.Q33960695
Androgen receptor signalling in the prostate.Q34105526
The epidermal growth factor receptor family as a central element for cellular signal transduction and diversificationQ34249785
In vivo amplification of the androgen receptor gene and progression of human prostate cancerQ34314274
Growth factors and their receptors: new targets for prostate cancer therapyQ34335662
Androgen receptor signaling in androgen-refractory prostate cancerQ34444942
The ups and downs of MEK kinase interactionsQ34453370
Androgen-dependent regulation of human MUC1 mucin expressionQ34775040
Expression and gene copy number analysis of ERBB2 oncogene in prostate cancerQ35788601
Analysis of genetic changes underlying local recurrence of prostate carcinoma during androgen deprivation therapy.Q35796528
Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cellsQ35846108
Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylationQ35849279
Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expressionQ36067596
Functional in vivo interaction between the amino-terminal, transactivation domain and the ligand binding domain of the androgen receptorQ38348552
Steroid hormone receptors and their regulation by phosphorylationQ38351829
Prognostic significance of HER-2/neu gene amplification status by fluorescence in situ hybridization of prostate carcinomaQ38474625
Alteration of the Tumor Suppressor Gene p53 in a High Fraction of Hormone Refractory Prostate CancerQ38480367
Elevated serum levels of p105(erbB-2) in patients with advanced-stage prostatic adenocarcinomaQ39434626
Mitogen-activated protein kinase kinase kinase 1 activates androgen receptor-dependent transcription and apoptosis in prostate cancerQ39446502
Elevated levels of circulating interleukin-6 and transforming growth factor-beta1 in patients with metastatic prostatic carcinomaQ39487932
Molecular implications of the antiandrogen withdrawal syndromeQ40403214
The mitogen-activated protein kinases, ERK1 and ERK2.Q40558045
Target populations and strategies for chemoprevention trials of prostate cancerQ40570879
Steroid hormone receptor phosphorylation: is there a physiological role?Q40686365
Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3beta inhibition and nuclear beta-catenin accumulationQ40725486
Androgen receptor expression is regulated by the phosphoinositide 3-kinase/Akt pathway in normal and tumoral epithelial cellsQ40736171
Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory stateQ40773957
Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen.Q40812297
HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway.Q40832627
Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expressionQ40877541
Activation of extracellular signal-regulated kinase in human prostate cancerQ40928024
Androgen receptor phosphorylationQ40931377
Prostatic intraepithelial neoplasia (PIN) and other prostatic lesions as risk factors and surrogate endpoints for cancer chemoprevention trialsQ40954859
Activation of the androgen receptor by polypeptide growth factors and cellular regulatorsQ40958221
Epidermal growth factor (EGF) receptor blockade inhibits the action of EGF, insulin-like growth factor I, and a protein kinase A activator on the mitogen-activated protein kinase pathway in prostate cancer cell linesQ40979803
The c-erbB3/HER3 receptor in human cancer.Q41203891
Androgenic and antiandrogenic control on epidermal growth factor, epidermal growth factor receptor, and androgen receptor expression in human prostate cancer cell line LNCaP.Q41337540
Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancerQ41344070
A potential autocrine loop between heregulin-alpha and erbB-3 receptor in human prostatic adenocarcinomaQ41366129
Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factorQ41435735
Frequent detection of codon 877 mutation in the androgen receptor gene in advanced prostate cancersQ41463454
Molecular and cellular biology of prostate cancerQ41474856
Androgens regulate proliferation of human prostate cancer cells in culture by increasing transforming growth factor-alpha (TGF-alpha) and epidermal growth factor (EGF)/TGF-alpha receptorQ41510695
Steroid requirement for androgen receptor dimerization and DNA binding. Modulation by intramolecular interactions between the NH2-terminal and steroid-binding domains.Q41528424
A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase.Q41615181
Androgen receptor phosphorylation, turnover, nuclear transport, and transcriptional activation. Specificity for steroids and antihormonesQ41643600
Steroid-independent activation of androgen receptor in androgen-independent prostate cancer: a possible role for the MAP kinase signal transduction pathway?Q41667115
Evidence for clonal outgrowth of androgen-independent prostate cancer cells from androgen-dependent tumors through a two-step processQ41695916
Autocrine regulation of DU145 human prostate cancer cell growth by epidermal growth factor-related polypeptidesQ41702970
Growth factor involvement in progression of prostate cancerQ41745741
Androgen receptor heterogeneity and phosphorylation in human LNCaP cellsQ41747633
Tissue expression of neu differentiation factor/heregulin and its receptor complex in prostate cancer and its biologic effects on prostate cancer cells in vitroQ42436009
Expression of androgen receptor and growth factors in premalignant lesions of the prostateQ42467183
Immunohistochemical comparative analysis of transforming growth factor alpha, epidermal growth factor, and epidermal growth factor receptor in normal, hyperplastic and neoplastic human prostatesQ42477282
Expression of epidermal growth factor receptor and ERBB2 (HER-2/Neu) oncoprotein in prostatic carcinomasQ43492345
A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapyQ43627769
Androgen blocks apoptosis of hormone-dependent prostate cancer cellsQ43675329
Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K.Q43708526
Androgen receptor alterations in prostate cancer relapsed during a combined androgen blockade by orchiectomy and bicalutamideQ43821771
Phosphoinositide metabolism in human prostate cancer cells in vitroQ44063536
A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgensQ44507804
Frequent inactivation of PTEN in prostate cancer cell lines and xenograftsQ47855108
Trends in prostate cancer incidence, mortality and survival in England and Wales 1971-1998.Q50661098
Her-2-neu expression and progression toward androgen independence in human prostate cancer.Q53800928
Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays.Q55032647
Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptorQ60594517
P433issue2
P921main subjectprostate cancerQ181257
P304page(s)99-109
P577publication date2003-03-01
P1433published inNeoplasiaQ2962042
P1476titleAndrogen-independent prostate cancer: potential role of androgen and ErbB receptor signal transduction crosstalk
P478volume5

Reverse relations

cites work (P2860)
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