scholarly article | Q13442814 |
P2093 | author name string | Fernando A. Gonzalez | |
Minh Tran | |||
Guido Lenz | |||
Qiongman Kong | |||
Zhongji Liao | |||
Yuan Kang | |||
Richard Rodnight | |||
Gary A. Weisman | |||
Joseph T. Neary | |||
Maria C. Jacques-Silva | |||
P2860 | cites work | Cloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy | Q24310825 |
Proteomic and functional evidence for a P2X7 receptor signalling complex | Q24535912 | ||
An RGD sequence in the P2Y(2) receptor interacts with alpha(V)beta(3) integrins and is required for G(o)-mediated signal transduction | Q24681126 | ||
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 | Q25938983 | ||
International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits | Q28199881 | ||
Molecular physiology of P2X receptors | Q28203477 | ||
Regulation of Akt/PKB activation by tyrosine phosphorylation | Q28205568 | ||
Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family | Q28206313 | ||
Receptors for purines and pyrimidines | Q28283941 | ||
The MAPK signaling cascade | Q28292599 | ||
AKT1/PKBα is recruited to lipid rafts and activated downstream of PKC isotypes in CD3‐induced T cell signaling | Q44411064 | ||
Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathway | Q44489751 | ||
Isoquinolines as antagonists of the P2X7 nucleotide receptor: high selectivity for the human versus rat receptor homologues | Q47866845 | ||
A P2X purinoceptor cDNA conferring a novel pharmacological profile | Q48069243 | ||
Synergistic activation of DNA synthesis in astrocytes by fibroblast growth factors and extracellular ATP. | Q48087145 | ||
Extracellular ATP induces stellation and increases glial fibrillary acidic protein content and DNA synthesis in primary astrocyte cultures | Q48206528 | ||
Evidence that multiple P2X purinoceptors are functionally expressed in rat supraoptic neurones | Q48329821 | ||
Mechanisms of P2X7 receptor-mediated ERK1/2 phosphorylation in human astrocytoma cells | Q48409005 | ||
P2 purinoceptors in rat cortical astrocytes: expression, calcium-imaging and signalling studies | Q48906126 | ||
Differential assembly of rat purinergic P2X7 receptor in immune cells of the brain and periphery | Q48907038 | ||
Pharmacological characterization of recombinant human and rat P2X receptor subtypes | Q48911279 | ||
Kinetics of cell lysis, dye uptake and permeability changes in cells expressing the rat P2X7 receptor. | Q52536118 | ||
Permeabilization of transformed mouse fibroblasts by 3'-O-(4-benzoyl)benzoyl adenosine 5'-triphosphate and the desensitization of the process. | Q54356339 | ||
P2Y receptors in brain astroglial cells: Identification of a gliotic P2Y receptor coupled to activation of a calcium-independent ras/ERK1/2 pathway | Q57405374 | ||
Shear stress stimulation of p130(cas) tyrosine phosphorylation requires calcium-dependent c-Src activation | Q64381277 | ||
Determination of total protein | Q71746469 | ||
Signaling by ATP receptors in astrocytes | Q72404318 | ||
Mitogenic signaling by ATP/P2Y purinergic receptors in astrocytes: involvement of a calcium-independent protein kinase C, extracellular signal-regulated protein kinase pathway distinct from the phosphatidylinositol-specific phospholipase C/calcium p | Q77789534 | ||
The activation of phosphatidylinositol 3-kinase by Ras | Q28305326 | ||
Pharmacological characterization of the human P2Y11 receptor | Q28343735 | ||
The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7) | Q28568856 | ||
A new class of ligand-gated ion channel defined by P2X receptor for extracellular ATP | Q28573068 | ||
Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation | Q29617586 | ||
Phosphoinositide kinases | Q29618047 | ||
P2X receptor expression on astrocytes in the nucleus accumbens of rats | Q30776060 | ||
Complexities of measuring antagonist potency at P2X(7) receptor orthologs. | Q31963256 | ||
Distribution of P2X receptors on astrocytes in juvenile rat hippocampus | Q33182449 | ||
Novel data point to a broader mechanism of action of oxidized ATP: the P2X7 receptor is not the only target | Q33193591 | ||
Cytolytic P2X purinoceptors. | Q33592245 | ||
Ca(2+)-permeable AMPA receptors induce phosphorylation of cAMP response element-binding protein through a phosphatidylinositol 3-kinase-dependent stimulation of the mitogen-activated protein kinase signaling cascade in neurons | Q33868171 | ||
Serine/threonine protein kinases and apoptosis. | Q33876765 | ||
Phosphoinositide 3-kinase signalling pathways | Q33940898 | ||
Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons | Q34296118 | ||
Ten years of protein kinase B signalling: a hard Akt to follow | Q34432885 | ||
PDK2: a complex tail in one Akt. | Q34467820 | ||
Effects of extracellular pH on agonism and antagonism at a recombinant P2X2 receptor. | Q35026478 | ||
Oxidized ATP (oATP) attenuates proinflammatory signaling via P2 receptor‐independent mechanisms | Q35045752 | ||
Extracellular ATP causes apoptosis and necrosis of cultured mesangial cells via P2Z/P2X7 receptors | Q36899638 | ||
Purinoceptors: are there families of P2X and P2Y purinoceptors? | Q40510363 | ||
ATP-stimulated Ca2+ influx and phospholipase D activities of a rat brain-derived type-2 astrocyte cell line, RBA-2, are mediated through P2X7 receptors | Q40945051 | ||
Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway | Q40986827 | ||
Structural basis of agonist-induced desensitization and sequestration of the P2Y2 nucleotide receptor. Consequences of truncation of the C terminus. | Q40999203 | ||
Trophic actions of extracellular nucleotides and nucleosides on glial and neuronal cells | Q41095944 | ||
Covalent incorporation of 3'-O-(4-benzoyl)benzoyl-ATP into a P2 purinoceptor in transformed mouse fibroblasts | Q41136718 | ||
Pharmacological characterization of heterologously expressed ATP-gated cation channels (P2x purinoceptors). | Q41321556 | ||
Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor | Q41559800 | ||
Mechanisms and consequences of activation of protein kinase B/Akt | Q41751003 | ||
2',3'-O-(2,4,6- trinitrophenyl) adenosine 5'-triphosphate (TNP-ATP)--a nanomolar affinity antagonist at rat mesenteric artery P2X receptor ion channels | Q42175834 | ||
Trinitrophenyl-substituted nucleotides are potent antagonists selective for P2X1, P2X3, and heteromeric P2X2/3 receptors. | Q42541961 | ||
Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976. | Q42558480 | ||
P(2Y) purinoceptor subtypes recruit different mek activators in astrocytes | Q42744879 | ||
Extracellular ATP and UTP activate the protein kinase B/Akt cascade via the P2Y(2) purinoceptor in renal mesangial cells | Q43263761 | ||
Brilliant blue G selectively blocks ATP-gated rat P2X(7) receptors. | Q43504221 | ||
Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways. | Q43694465 | ||
P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase. | Q43732527 | ||
The tyrosine kinase c-Src is required for 1,25(OH)2-vitamin D3 signalling to the nucleus in muscle cells | Q43832509 | ||
Native group-III metabotropic glutamate receptors are coupled to the mitogen-activated protein kinase/phosphatidylinositol-3-kinase pathways | Q44068680 | ||
Adenosine-mediated activation of Akt/protein kinase B in the rat hippocampus in vitro and in vivo | Q44074063 | ||
Vascular endothelial growth factor induces protein kinase C (PKC)-dependent Akt/PKB activation and phosphatidylinositol 3'-kinase-mediates PKC delta phosphorylation: role of PKC in angiogenesis | Q44177623 | ||
Signaling pathway from the human adenosine A(3) receptor expressed in Chinese hamster ovary cells to the extracellular signal-regulated kinase 1/2. | Q44187742 | ||
Induction of COX-2 and reactive gliosis by P2Y receptors in rat cortical astrocytes is dependent on ERK1/2 but independent of calcium signalling | Q44242854 | ||
P2X7 receptor-mediated release of excitatory amino acids from astrocytes. | Q44323454 | ||
Insulin-induced Akt activation is inhibited by angiotensin II in the vasculature through protein kinase C-alpha | Q44353846 | ||
Metabotropic glutamate receptor activation enhances the activities of two types of Ca2+-activated k+ channels in rat hippocampal astrocytes. | Q44357319 | ||
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phosphorylation | Q242736 |
astrocyte | Q502961 | ||
P304 | page(s) | 1106–1117 | |
P577 | publication date | 2004-04-01 | |
P1433 | published in | British Journal of Pharmacology | Q919631 |
P1476 | title | P2X7 receptors stimulate AKT phosphorylation in astrocytes | |
P478 | volume | 141 |
Q28513626 | A role for mitogen-activated protein kinase(Erk1/2) activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death |
Q28568956 | ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages |
Q43794059 | ATP and UTP stimulate bone morphogenetic protein-2,-4 and -5 gene expression and mineralization by rat primary osteoblasts involving PI3K/AKT pathway |
Q41135485 | ATP induces mild hypothermia in rats but has a strikingly detrimental impact on focal cerebral ischemia. |
Q37337353 | Akt1 mediates purinergic-dependent NOS3 activation in thick ascending limbs |
Q37995668 | Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation |
Q48219333 | Astrocyte-mediated ischemic tolerance |
Q45230304 | Bi-functional effects of ATP/P2 receptor activation on tumor necrosis factor-alpha release in lipopolysaccharide-stimulated astrocytes |
Q28079371 | Brilliant Blue Dyes in Daily Food: How Could Purinergic System Be Affected? |
Q36173797 | Cell cycle regulation of astrocytes by extracellular nucleotides and fibroblast growth factor-2 |
Q40457686 | ERK, PKC and PI3K/Akt pathways mediate extracellular ATP and adenosine-induced proliferation of U138-MG human glioma cell line. |
Q36156190 | Extracellular ATP induces graded reactive response of astrocytes and strengthens their antioxidative defense in vitro |
Q42858882 | Extracellular high dosages of adenosine triphosphate induce inflammatory response and insulin resistance in rat adipocytes |
Q38870205 | Extracellular purines, purinergic receptors and tumor growth. |
Q39297821 | Ezrin/radixin/moesin are required for the purinergic P2X7 receptor (P2X7R)-dependent processing of the amyloid precursor protein |
Q39352158 | Glucose transporter 2 expression is down regulated following P2X7 activation in enterocytes |
Q39530433 | Hypoxia-increased RAGE and P2X7R expression regulates tumor cell invasion through phosphorylation of Erk1/2 and Akt and nuclear translocation of NF-{kappa}B. |
Q48368241 | Hypoxia-independent mechanisms of HIF-1α expression in astrocytes after ischemic preconditioning |
Q43051770 | Large-conductance channel formation mediated by P2X7 receptor activation is regulated through distinct intracellular signaling pathways in peritoneal macrophages and 2BH4 cells |
Q42826252 | Mechanisms of the ATP potentiation of hyposmotic taurine release in Swiss 3T3 fibroblasts |
Q37348367 | Membrane compartments and purinergic signalling: the role of plasma membrane microdomains in the modulation of P2XR-mediated signalling. |
Q30160213 | Molecular determinants of P2Y2 nucleotide receptor function: implications for proliferative and inflammatory pathways in astrocytes |
Q38005033 | Neuroprotective roles of the P2Y(2) receptor. |
Q46581514 | Norepinephrine triggers release of glial ATP to increase postsynaptic efficacy. |
Q36460476 | Nucleotide signaling in nervous system development |
Q45415152 | P2 receptor-mediated stimulation of the PI3-K/Akt-pathway in vivo |
Q36463093 | P2 receptors and neuronal injury |
Q37998945 | P2 receptors for extracellular nucleotides in the central nervous system: role of P2X7 and P2Y₂ receptor interactions in neuroinflammation |
Q37947554 | P2X receptors and their roles in astroglia in the central and peripheral nervous system |
Q36173773 | P2X(7) receptor: Death or life? |
Q36606127 | P2X(7) receptors: properties and relevance to CNS function |
Q92799403 | P2X7 Interactions and Signaling - Making Head or Tail of It |
Q36200053 | P2X7 Receptor Function in Bone-Related Cancer |
Q47769804 | P2X7R antagonism after subfailure overstretch injury of blood vessels reverses vasomotor dysfunction and prevents apoptosis. |
Q39425060 | P2X₇-mediated calcium influx triggers a sustained, PI3K-dependent increase in metabolic acid production by osteoblast-like cells |
Q36842750 | P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis |
Q48531462 | Pathological potential of astroglial purinergic receptors |
Q28384801 | Pathophysiology of astroglial purinergic signalling |
Q37389355 | Physiological and pathological functions of P2X7 receptor in the spinal cord |
Q49917383 | Physiology of Astroglia |
Q47222038 | Prostaglandin E2 Impairs P2Y2/P2Y4 Receptor Signaling in Cerebellar Astrocytes via EP3 Receptors |
Q43267367 | Purine nucleotides reduce superoxide production by nitric oxide synthase in a murine sepsis model |
Q89604984 | Purinergic Signaling in Glioma Progression |
Q41704552 | Purinergic receptor X7 mediates leptin induced GLUT4 function in stellate cells in nonalcoholic steatohepatitis. |
Q46817699 | Purinergic receptor signaling regulates N-cadherin expression in primary astrocyte cultures |
Q28573378 | Purinergic signaling induces thrombospondin-1 expression in astrocytes |
Q34629041 | Purinergic signaling is required for fluid shear stress-induced NF-κB translocation in osteoblasts |
Q37414083 | Purinoceptors on neuroglia |
Q36174059 | Roles of P2 receptors in glial cells: focus on astrocytes |
Q36161824 | Signaling from P2 nucleotide receptors to protein kinase cascades induced by CNS injury: implications for reactive gliosis and neurodegeneration |
Q35838105 | Silencing P2X7 receptor downregulates the expression of TCP-1 involved in lymphoma lymphatic metastasis |
Q50202418 | The P2X7 Receptor in Inflammatory Diseases: Angel or Demon? |
Q24296731 | The P2X7 receptor is a key modulator of aerobic glycolysis |
Q41034427 | The role of microglial P2X7: modulation of cell death and cytokine release |
Q55317709 | The two faces of pannexins: new roles in inflammation and repair. |
Q46856693 | Vascular surgical stretch injury leads to activation of P2X7 receptors and impaired endothelial function |
Q36747748 | eIF2B and oligodendrocyte survival: where nature and nurture meet in bipolar disorder and schizophrenia? |
Search more.