P2X7 receptors stimulate AKT phosphorylation in astrocytes

scientific journal article

P2X7 receptors stimulate AKT phosphorylation in astrocytes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/SJ.BJP.0705685
P3181OpenCitations bibliographic resource ID2898019
P932PMC publication ID1574879
P698PubMed publication ID15023862
P5875ResearchGate publication ID8677033

P2093author name stringFernando A. Gonzalez
Minh Tran
Guido Lenz
Qiongman Kong
Zhongji Liao
Yuan Kang
Richard Rodnight
Gary A. Weisman
Joseph T. Neary
Maria C. Jacques-Silva
P2860cites workCloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapyQ24310825
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An RGD sequence in the P2Y(2) receptor interacts with alpha(V)beta(3) integrins and is required for G(o)-mediated signal transductionQ24681126
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunitsQ28199881
Molecular physiology of P2X receptorsQ28203477
Regulation of Akt/PKB activation by tyrosine phosphorylationQ28205568
Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor familyQ28206313
Receptors for purines and pyrimidinesQ28283941
The MAPK signaling cascadeQ28292599
AKT1/PKBα is recruited to lipid rafts and activated downstream of PKC isotypes in CD3‐induced T cell signalingQ44411064
Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathwayQ44489751
Isoquinolines as antagonists of the P2X7 nucleotide receptor: high selectivity for the human versus rat receptor homologuesQ47866845
A P2X purinoceptor cDNA conferring a novel pharmacological profileQ48069243
Synergistic activation of DNA synthesis in astrocytes by fibroblast growth factors and extracellular ATP.Q48087145
Extracellular ATP induces stellation and increases glial fibrillary acidic protein content and DNA synthesis in primary astrocyte culturesQ48206528
Evidence that multiple P2X purinoceptors are functionally expressed in rat supraoptic neuronesQ48329821
Mechanisms of P2X7 receptor-mediated ERK1/2 phosphorylation in human astrocytoma cellsQ48409005
P2 purinoceptors in rat cortical astrocytes: expression, calcium-imaging and signalling studiesQ48906126
Differential assembly of rat purinergic P2X7 receptor in immune cells of the brain and peripheryQ48907038
Pharmacological characterization of recombinant human and rat P2X receptor subtypesQ48911279
Kinetics of cell lysis, dye uptake and permeability changes in cells expressing the rat P2X7 receptor.Q52536118
Permeabilization of transformed mouse fibroblasts by 3'-O-(4-benzoyl)benzoyl adenosine 5'-triphosphate and the desensitization of the process.Q54356339
P2Y receptors in brain astroglial cells: Identification of a gliotic P2Y receptor coupled to activation of a calcium-independent ras/ERK1/2 pathwayQ57405374
Shear stress stimulation of p130(cas) tyrosine phosphorylation requires calcium-dependent c-Src activationQ64381277
Determination of total proteinQ71746469
Signaling by ATP receptors in astrocytesQ72404318
Mitogenic signaling by ATP/P2Y purinergic receptors in astrocytes: involvement of a calcium-independent protein kinase C, extracellular signal-regulated protein kinase pathway distinct from the phosphatidylinositol-specific phospholipase C/calcium pQ77789534
The activation of phosphatidylinositol 3-kinase by RasQ28305326
Pharmacological characterization of the human P2Y11 receptorQ28343735
The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)Q28568856
A new class of ligand-gated ion channel defined by P2X receptor for extracellular ATPQ28573068
Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activationQ29617586
Phosphoinositide kinasesQ29618047
P2X receptor expression on astrocytes in the nucleus accumbens of ratsQ30776060
Complexities of measuring antagonist potency at P2X(7) receptor orthologs.Q31963256
Distribution of P2X receptors on astrocytes in juvenile rat hippocampusQ33182449
Novel data point to a broader mechanism of action of oxidized ATP: the P2X7 receptor is not the only targetQ33193591
Cytolytic P2X purinoceptors.Q33592245
Ca(2+)-permeable AMPA receptors induce phosphorylation of cAMP response element-binding protein through a phosphatidylinositol 3-kinase-dependent stimulation of the mitogen-activated protein kinase signaling cascade in neuronsQ33868171
Serine/threonine protein kinases and apoptosis.Q33876765
Phosphoinositide 3-kinase signalling pathwaysQ33940898
Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neuronsQ34296118
Ten years of protein kinase B signalling: a hard Akt to followQ34432885
PDK2: a complex tail in one Akt.Q34467820
Effects of extracellular pH on agonism and antagonism at a recombinant P2X2 receptor.Q35026478
Oxidized ATP (oATP) attenuates proinflammatory signaling via P2 receptor‐independent mechanismsQ35045752
Extracellular ATP causes apoptosis and necrosis of cultured mesangial cells via P2Z/P2X7 receptorsQ36899638
Purinoceptors: are there families of P2X and P2Y purinoceptors?Q40510363
ATP-stimulated Ca2+ influx and phospholipase D activities of a rat brain-derived type-2 astrocyte cell line, RBA-2, are mediated through P2X7 receptorsQ40945051
Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathwayQ40986827
Structural basis of agonist-induced desensitization and sequestration of the P2Y2 nucleotide receptor. Consequences of truncation of the C terminus.Q40999203
Trophic actions of extracellular nucleotides and nucleosides on glial and neuronal cellsQ41095944
Covalent incorporation of 3'-O-(4-benzoyl)benzoyl-ATP into a P2 purinoceptor in transformed mouse fibroblastsQ41136718
Pharmacological characterization of heterologously expressed ATP-gated cation channels (P2x purinoceptors).Q41321556
Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptorQ41559800
Mechanisms and consequences of activation of protein kinase B/AktQ41751003
2',3'-O-(2,4,6- trinitrophenyl) adenosine 5'-triphosphate (TNP-ATP)--a nanomolar affinity antagonist at rat mesenteric artery P2X receptor ion channelsQ42175834
Trinitrophenyl-substituted nucleotides are potent antagonists selective for P2X1, P2X3, and heteromeric P2X2/3 receptors.Q42541961
Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976.Q42558480
P(2Y) purinoceptor subtypes recruit different mek activators in astrocytesQ42744879
Extracellular ATP and UTP activate the protein kinase B/Akt cascade via the P2Y(2) purinoceptor in renal mesangial cellsQ43263761
Brilliant blue G selectively blocks ATP-gated rat P2X(7) receptors.Q43504221
Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways.Q43694465
P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase.Q43732527
The tyrosine kinase c-Src is required for 1,25(OH)2-vitamin D3 signalling to the nucleus in muscle cellsQ43832509
Native group-III metabotropic glutamate receptors are coupled to the mitogen-activated protein kinase/phosphatidylinositol-3-kinase pathwaysQ44068680
Adenosine-mediated activation of Akt/protein kinase B in the rat hippocampus in vitro and in vivoQ44074063
Vascular endothelial growth factor induces protein kinase C (PKC)-dependent Akt/PKB activation and phosphatidylinositol 3'-kinase-mediates PKC delta phosphorylation: role of PKC in angiogenesisQ44177623
Signaling pathway from the human adenosine A(3) receptor expressed in Chinese hamster ovary cells to the extracellular signal-regulated kinase 1/2.Q44187742
Induction of COX-2 and reactive gliosis by P2Y receptors in rat cortical astrocytes is dependent on ERK1/2 but independent of calcium signallingQ44242854
P2X7 receptor-mediated release of excitatory amino acids from astrocytes.Q44323454
Insulin-induced Akt activation is inhibited by angiotensin II in the vasculature through protein kinase C-alphaQ44353846
Metabotropic glutamate receptor activation enhances the activities of two types of Ca2+-activated k+ channels in rat hippocampal astrocytes.Q44357319
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
astrocyteQ502961
P304page(s)1106–1117
P577publication date2004-04-01
P1433published inBritish Journal of PharmacologyQ919631
P1476titleP2X7 receptors stimulate AKT phosphorylation in astrocytes
P478volume141

Reverse relations

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