| scholarly article | Q13442814 |
| P356 | DOI | 10.1124/MOL.54.1.22 |
| P698 | PubMed publication ID | 9658186 |
| P2093 | author name string | G R Dubyak | |
| J Rice | |||
| C Virginio | |||
| A Surprenant | |||
| B D Humphreys | |||
| P433 | issue | 1 | |
| P304 | page(s) | 22-32 | |
| P577 | publication date | 1998-07-01 | |
| P1433 | published in | Molecular Pharmacology | Q1943386 |
| P1476 | title | Isoquinolines as antagonists of the P2X7 nucleotide receptor: high selectivity for the human versus rat receptor homologues | |
| P478 | volume | 54 |
| Q36725685 | ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine way |
| Q35748675 | ATP-P2X7 receptor signaling controls basal and TNFα-stimulated glial cell proliferation |
| Q35122793 | Activation and regulation of purinergic P2X receptor channels |
| Q43701646 | Activity-dependent development of P2X7 current and Ca2+ entry in rabbit osteoclasts |
| Q37122033 | Adenine nucleotide analogues locked in a Northern methanocarba conformation: enhanced stability and potency as P2Y(1) receptor agonists |
| Q40878368 | Antagonist effects on human P2X(7) receptor-mediated cellular accumulation of YO-PRO-1. |
| Q40892261 | Antagonists of P2 receptor prevent NGF-dependent neuritogenesis in PC12 cells |
| Q40883984 | Apparent species differences in the kinetic properties of P2X(7) receptors |
| Q39926483 | Astrocyte cultures exhibit P2X7 receptor channel opening in the absence of exogenous ligands |
| Q39882281 | Atypical P2X receptor pharmacology in two human osteoblast-like cell lines. |
| Q42453001 | Basal and inducible expression of the thiol-sensitive ART2.1 ecto-ADP-ribosyltransferase in myeloid and lymphoid leukocytes |
| Q35981557 | Brilliant blue FCF is a nontoxic dye for saphenous vein graft marking that abrogates response to injury |
| Q35041965 | Bromoenol lactone enhances the permeabilization of rat submandibular acinar cells by P2X7 agonists |
| Q40813474 | C-terminal calmodulin-binding motif differentially controls human and rat P2X7 receptor current facilitation |
| Q34675786 | Ca2+/calmodulin-dependent protein kinase II inhibitors disrupt AKAP79-dependent PKC signaling to GluA1 AMPA receptors |
| Q42145843 | Characterisation of the R276A gain-of-function mutation in the ectodomain of murine P2X7 |
| Q40221922 | Characterization of a selective and potent antagonist of human P2X(7) receptors, AZ11645373. |
| Q28512436 | Cloning and functional characterisation of the mouse P2X7 receptor |
| Q33509374 | Cloning and pharmacological characterization of the dog P2X7 receptor |
| Q33307130 | Cloning and pharmacological characterization of the guinea pig P2X7 receptor orthologue |
| Q43054772 | Connexin hemichannels and gap junction channels are differentially influenced by lipopolysaccharide and basic fibroblast growth factor |
| Q33768384 | Developments in P2 receptor targeted therapeutics |
| Q37401620 | Differential regulation of P2X7 receptor activation by extracellular nicotinamide adenine dinucleotide and ecto-ADP-ribosyltransferases in murine macrophages and T cells. |
| Q42085394 | Diinosine pentaphosphate (IP5I) is a potent antagonist at recombinant rat P2X1 receptors. |
| Q41556777 | Direct labelling of the human P2X7 receptor and identification of positive and negative cooperativity of binding |
| Q36807452 | Discovery of P2X7 receptor-selective antagonists offers new insights into P2X7 receptor function and indicates a role in chronic pain states |
| Q40811383 | Docking of competitive inhibitors to the P2X7 receptor family reveals key differences responsible for changes in response between rat and human |
| Q35751575 | Dynamic mass redistribution assays decode surface influence on signaling of endogenous purinergic P2Y receptors. |
| Q37135563 | Dynamic purine signaling and metabolism during neutrophil-endothelial interactions |
| Q36661625 | Effects of toxic cellular stresses and divalent cations on the human P2X7 cell death receptor |
| Q40628667 | Extracellular ATP and adenosine induce cell apoptosis of human hepatoma Li‐7A cells via the A3 adenosine receptor |
| Q46391153 | Extracellular ATP induces cytokine expression and apoptosis through P2X7 receptor in murine mast cells |
| Q36095121 | Extracellular ATP is cytotoxic to mononuclear phagocytes but does not induce killing of intracellular Mycobacterium avium subsp. paratuberculosis |
| Q33214204 | Functional diversity of AT2 receptor orthologues in closely related species |
| Q37346536 | Functional evidence for the expression of P2X1, P2X4 and P2X7 receptors in human lung mast cells. |
| Q40703508 | Functionalized congeners of tyrosine-based P2X(7) receptor antagonists: probing multiple sites for linking and dimerization |
| Q43510878 | Glucose deprivation and chemical hypoxia: neuroprotection by P2 receptor antagonists |
| Q40489559 | Human β Defensin-3 Increases CD86 Expression on Monocytes by Activating the ATP-Gated Channel P2X7. |
| Q41594118 | Identification of Thr283 as a key determinant of P2X7 receptor function |
| Q39956832 | Identification of regions of the P2X(7) receptor that contribute to human and rat species differences in antagonist effects |
| Q28344394 | In search of selective P2 receptor ligands: interaction of dihydropyridine derivatives at recombinant rat P2X(2) receptors |
| Q37139376 | Inhibition of P2X(7) receptors by divalent cations: old action and new insight |
| Q33637655 | Inhibition of neuronal cell death after retinoic acid-induced down-regulation of P2X7 nucleotide receptor expression |
| Q43111428 | Inhibition of neutrophil apoptosis by ATP is mediated by the P2Y11 receptor. |
| Q41886797 | Intracellular calcium changes trigger connexin 32 hemichannel opening |
| Q42130020 | Involvement of P2X receptors in the NAD(+)-induced rise in [Ca (2+)] (i) in human monocytes |
| Q35781225 | Kinetics of P2X7 receptor-operated single channels currents |
| Q39832611 | Mammalian P2X7 receptor pharmacology: comparison of recombinant mouse, rat and human P2X7 receptors |
| Q39868976 | Mechanism of action of species-selective P2X(7) receptor antagonists |
| Q24617046 | Molecular and functional properties of P2X receptors--recent progress and persisting challenges |
| Q33201399 | Molecular recognition at purine and pyrimidine nucleotide (P2) receptors. |
| Q40037039 | Negative and positive allosteric modulators of the P2X(7) receptor |
| Q34158330 | Non-synonymous single nucleotide polymorphisms in the P2X receptor genes: association with diseases, impact on receptor functions and potential use as diagnosis biomarkers |
| Q35830419 | Nucleoside Reverse Transcriptase Inhibitors Suppress Laser-Induced Choroidal Neovascularization in Mice |
| Q35045752 | Oxidized ATP (oATP) attenuates proinflammatory signaling via P2 receptor‐independent mechanisms |
| Q37135491 | P2 purinergic receptor modulation of cytokine production |
| Q43960634 | P2 receptor modulation and cytotoxic function in cultured CNS neurons |
| Q44506085 | P2X and P2Y purinoceptor expression in pancreas from streptozotocin-diabetic rats |
| Q38068620 | P2X receptors as drug targets |
| Q36173773 | P2X(7) receptor: Death or life? |
| Q64943174 | P2X7 ionotropic receptor is functionally expressed in rabbit articular chondrocytes and mediates extracellular ATP cytotoxicity. |
| Q46041460 | P2X7 nucleotide receptor is coupled to GSK-3 inhibition and neuroprotection in cerebellar granule neurons. |
| Q74139671 | P2X7 receptors in Müller glial cells from the human retina |
| Q44626268 | P2X7 receptors in rat brain: presence in synaptic terminals and granule cells. |
| Q28564711 | P2X7 receptors stimulate AKT phosphorylation in astrocytes |
| Q40861211 | Permeabilization via the P2X7 purinoreceptor reveals the presence of a Ca2+-activated Cl- conductance in the apical membrane of murine tracheal epithelial cells |
| Q39640370 | Pharmacological properties and physiological function of a P2X-like current in single proximal tubule cells isolated from frog kidney |
| Q38650165 | Pharmacological properties of the rhesus macaque monkey P2X7 receptor |
| Q28237411 | Pharmacology of P2X channels |
| Q38135247 | Physiological roles and potential therapeutic applications of the P2X7 receptor in inflammation and pain |
| Q40960421 | Pore dilation of neuronal P2X receptor channels |
| Q42489612 | Pore properties and pharmacological features of the P2X receptor channel in airway ciliated cells |
| Q36726800 | Potent P2X7 Receptor Antagonists: Tyrosyl Derivatives Synthesized Using a Sequential Parallel Synthetic Approach |
| Q33874895 | Purinergic and pyrimidinergic receptors as potential drug targets |
| Q37586481 | Recent patents on novel P2X(7) receptor antagonists and their potential for reducing central nervous system inflammation |
| Q42650027 | Residues 155 and 348 contribute to the determination of P2X7 receptor function via distinct mechanisms revealed by single-nucleotide polymorphisms |
| Q28361214 | Serum constituents can affect 2'-& 3'-O-(4-benzoylbenzoyl)-ATP potency at P2X(7) receptors |
| Q43263816 | Stimulation of Ca(2+) influx through ATP receptors on rat brain synaptosomes: identification of functional P2X(7) receptor subtypes |
| Q40956148 | Structure-activity relationships of bisphosphate nucleotide derivatives as P2Y1 receptor antagonists and partial agonists. |
| Q36092090 | Structure-based identification and characterisation of structurally novel human P2X7 receptor antagonists |
| Q42467888 | Study on the activation of phospholipases A2 by purinergic agonists in rat submandibular ductal cells. |
| Q39014384 | Suppression of cell membrane permeability by suramin: involvement of its inhibitory actions on connexin 43 hemichannels |
| Q48865628 | The P2X(7) receptor from Xenopus laevis: formation of a large pore in Xenopus oocytes |
| Q43568198 | The P2X7 purinergic receptor on bovine macrophages mediates mycobacterial death |
| Q36981077 | The cytokine IL-1beta transiently enhances P2X7 receptor expression and function in human astrocytes. |
| Q37142680 | The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner. |
| Q50724270 | The suramin analogue NF279 is a novel and potent antagonist selective for the P2X(1) receptor. |
| Q42082561 | Uric acid induces caspase-1 activation, IL-1β secretion and P2X7 receptor dependent proliferation in primary human lymphocytes |
| Q34633667 | Vascular CD39/ENTPD1 directly promotes tumor cell growth by scavenging extracellular adenosine triphosphate |
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