Neuron-NG2 cell synapses: novel functions for regulating NG2 cell proliferation and differentiation

scientific article published on August 2013

Neuron-NG2 cell synapses: novel functions for regulating NG2 cell proliferation and differentiation is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1155/2013/402843
P932PMC publication ID3747365
P698PubMed publication ID23984358
P5875ResearchGate publication ID256191066

P2093author name stringZhong-Xiang Yao
Jia-Xiang Xiong
Qian-Kun Yang
P2860cites workATP stimulates mouse embryonic stem cell proliferation via protein kinase C, phosphatidylinositol 3-kinase/Akt, and mitogen-activated protein kinase signaling pathways.Q50476628
NG2-positive cells in the mouse white and grey matter display distinct physiological properties.Q50793239
Mouse alpha1B-adrenergic receptor is expressed in neurons and NG2 oligodendrocytes.Q50794433
Proliferation of oligodendrocyte precursor cells depends on electrical activity in axons.Q51673282
Glial cells in the mouse hippocampus express AMPA receptors with an intermediate Ca2+ permeabilityQ70803946
Oligodendrocyte progenitor cell proliferation and lineage progression are regulated by glutamate receptor-mediated K+ channel blockQ71483880
CAK-Cyclin-dependent Activating Kinase: a key kinase in cell cycle control and a target for drugs?Q24301459
Understanding pRb: toward the necessary development of targeted treatments for retinoblastomaQ27011911
Nonsynaptic Communication Through ATP Release from Volume-Activated Anion Channels in AxonsQ27329978
The INK4 family of cell cycle inhibitors in cancerQ28145080
The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signalingQ28216364
Cyclin-dependent kinases: engines, clocks, and microprocessorsQ29614786
Dividing glial cells maintain differentiated properties including complex morphology and functional synapsesQ30485201
Metabotropic P2 receptor activation regulates oligodendrocyte progenitor migration and development.Q31142299
Excitability and synaptic communication within the oligodendrocyte lineageQ33725968
The role of oligodendrocytes and oligodendrocyte progenitors in CNS remyelinationQ33817395
Bioelectric controls of cell proliferation: ion channels, membrane voltage and the cell cycleQ33822451
Neuron-glia synapses in the brain.Q33823760
Cells expressing the NG2 antigen contact nodes of Ranvier in adult CNS white matterQ33855872
Cell-cycle inhibitors: three families united by a common causeQ33895611
Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus.Q33902645
Phosphoinositide 3-kinase signalling pathwaysQ33940898
NG2-expressing glial progenitor cells: an abundant and widespread population of cycling cells in the adult rat CNS.Q33973335
Regulation of Kv1 subunit expression in oligodendrocyte progenitor cells and their role in G1/S phase progression of the cell cycleQ34013276
NMDA antagonist inhibits the extracellular signal-regulated kinase pathway and suppresses cancer growthQ34098628
The fate of synaptic input to NG2 glial cells: neurons specifically downregulate transmitter release onto differentiating oligodendroglial cells.Q34121196
Calcium signalling in cells of oligodendroglial lineageQ34199616
Polydendrocytes display large lineage plasticity following focal cerebral ischemiaQ34271030
Properties and fate of oligodendrocyte progenitor cells in the corpus callosum, motor cortex, and piriform cortex of the mouseQ34281663
Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelinQ34337961
INK4 proteins, a family of mammalian CDK inhibitors with novel biological functions.Q34656077
NG2 cells generate both oligodendrocytes and gray matter astrocytes.Q34719495
Glial cells are born with synapses.Q34777552
Functions of PI 3-kinase in development of the nervous systemQ34783898
Cdk2 loss accelerates precursor differentiation and remyelination in the adult central nervous systemQ34825266
PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice.Q34851255
Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticityQ34908170
Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms.Q34989521
Glial neuronal signaling in the central nervous systemQ35083788
Nonsynaptic and nonvesicular ATP release from neurons and relevance to neuron-glia signalingQ35186727
Bidirectional plasticity of calcium-permeable AMPA receptors in oligodendrocyte lineage cellsQ35477152
Physiological characteristics of NG2-expressing glial cellsQ35539095
Asymmetry-defective oligodendrocyte progenitors are glioma precursorsQ35814886
Synaptic signaling between neurons and glia.Q35836084
Differential phosphorylation of NG2 proteoglycan by ERK and PKCalpha helps balance cell proliferation and migrationQ36118785
Experience-dependent regulation of NG2 progenitors in the developing barrel cortexQ36219795
Cdk2 is critical for proliferation and self-renewal of neural progenitor cells in the adult subventricular zoneQ36274559
Vesicular release of glutamate from unmyelinated axons in white matterQ36275086
Nerve impulses regulate myelination through purinergic signallingQ36521720
Synaptic communication between neurons and NG2+ cellsQ36589945
A morphological and electrophysiological study on the postnatal development of oligodendrocyte precursor cells in the rat brainQ48903327
P2 purinoceptors in rat cortical astrocytes: expression, calcium-imaging and signalling studiesQ48906126
Neurotransmitter-mediated calcium signalling in oligodendrocyte physiology and pathologyQ36606100
Do Action Potentials Regulate Myelination?Q36638522
NMDA Receptors in gliaQ36710663
Polydendrocytes: NG2 cells with many roles in development and repair of the CNS.Q36710674
Morphological and physiological interactions of NG2-glia with astrocytes and neuronsQ36801709
Control of cell proliferation by neurotransmitters in the developing vertebrate retinaQ36863417
Synapses on NG2-expressing progenitors in the brain: multiple functions?Q37219369
Ca(2+) signaling evoked by activation of Na(+) channels and Na(+)/Ca(2+) exchangers is required for GABA-induced NG2 cell migration.Q37267699
Voltage-operated Ca(2+) and Na(+) channels in the oligodendrocyte lineageQ37330291
Characteristics and functions of NG2 cells in normal brain and neuropathologyQ37418268
NG2 cells: Properties, progeny and originQ37665589
Synantocytes: the fifth type of glia? In comparison with astrocytesQ37776945
Cells of the oligodendroglial lineage, myelination, and remyelinationQ37795984
Is neuronal communication with NG2 cells synaptic or extrasynaptic?Q37847221
Synapses between NG2 glia and neuronsQ37852077
The complex world of oligodendroglial differentiation inhibitorsQ37869047
Fate of neuron-glia synapses during proliferation and differentiation of NG2 cellsQ37876939
Post-transcriptional regulation of the Ras-ERK/MAPK signaling pathwayQ37891908
Postnatal switch from synaptic to extrasynaptic transmission between interneurons and NG2 cellsQ39702275
Activation of MAP kinase by muscarinic cholinergic receptors induces cell proliferation and protein synthesis in human breast cancer cells.Q40451282
Glutamate enhances survival and proliferation of neural progenitors derived from the subventricular zone.Q40463967
Cyclin-dependent kinase-2 controls oligodendrocyte progenitor cell cycle progression and is downregulated in adult oligodendrocyte progenitors.Q40701044
Control of pRB phosphorylationQ41732727
NMDA receptors are expressed in oligodendrocytes and activated in ischaemia.Q41843868
Oligodendrocyte differentiation from adult multipotent stem cells is modulated by glutamateQ41952360
Loss of Cdk2 and Cdk4 induces a switch from proliferation to differentiation in neural stem cells.Q42505393
P2Y receptor-mediated stimulation of Müller glial DNA synthesis.Q42517959
ATP-evoked Ca2+ mobilisation and prostanoid release from astrocytes: P2-purinergic receptors linked to phosphoinositide hydrolysisQ42651184
C5b-9-activated, K(v)1.3 channels mediate oligodendrocyte cell cycle activation and dedifferentiationQ42829214
Cell cycle dynamics of NG2 cells in the postnatal and ageing brainQ43117221
Kainate receptors and signal integration by NG2 glial cellsQ43212884
C5b-9 terminal complement complex protects oligodendrocytes from death by regulating Bad through phosphatidylinositol 3-kinase/Akt pathwayQ43699084
AMPA glutamate receptor-mediated calcium signaling is transiently enhanced during development of oligodendrocytes.Q44027716
P2Y receptor-mediated stimulation of Müller glial cell DNA synthesis: dependence on EGF and PDGF receptor transactivationQ44324758
Adenosine triphosphate induces proliferation of human neural stem cells: Role of calcium and p70 ribosomal protein S6 kinaseQ44401723
Synaptic signaling between GABAergic interneurons and oligodendrocyte precursor cells in the hippocampus.Q44683771
Axons and astrocytes release ATP and glutamate to evoke calcium signals in NG2-glia.Q45966072
Functional alpha 7-containing nicotinic receptors of NG2-expressing cells in the hippocampus.Q46146798
Climbing fiber innervation of NG2-expressing glia in the mammalian cerebellum.Q46517790
K+ channel KV3.1 associates with OSP/claudin-11 and regulates oligodendrocyte developmentQ46520807
Downregulation of platelet-derived growth factor-alpha receptor-mediated tyrosine kinase activity as a cellular mechanism for K+-channel regulation during oligodendrocyte development in situ.Q46715120
A role for glutamate and its receptors in the regulation of oligodendrocyte development in cerebellar tissue slicesQ47875735
Voltage-activated K+ channels and membrane depolarization regulate accumulation of the cyclin-dependent kinase inhibitors p27(Kip1) and p21(CIP1) in glial progenitor cells.Q48181194
Properties of GABA and glutamate responses in identified glial cells of the mouse hippocampal slice.Q48185548
Vesicular glutamate release from axons in white matter.Q48275933
Localization of the mouse alpha1A-adrenergic receptor (AR) in the brain: alpha1AAR is expressed in neurons, GABAergic interneurons, and NG2 oligodendrocyte progenitorsQ48536746
Sodium channel currents in rat hippocampal NG2 glia: characterization and contribution to resting membrane potentialQ48550433
K+ channel expression and cell proliferation are regulated by intracellular sodium and membrane depolarization in oligodendrocyte progenitor cellsQ48728329
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectcell differentiationQ210861
cellQ7868
carbohydrateQ11358
nervous systemQ9404
P304page(s)402843
P577publication date2013-08-01
P1433published inBioMed Research InternationalQ17509958
P1476titleNeuron-NG2 cell synapses: novel functions for regulating NG2 cell proliferation and differentiation
P478volume2013

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cites work (P2860)
Q38594660Behavioral experiences as drivers of oligodendrocyte lineage dynamics and myelin plasticity.
Q39680626Changes in the proliferative capacity of NG2 cell subpopulations during postnatal development of the mouse hippocampus
Q51552458Characterization of Gene Expression in the Rat Brainstem After Neonatal Hypoxic-Ischemic Injury and Antioxidant Treatment.
Q35253106Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease
Q48485387Glial Cells and Integrity of the Nervous System
Q92871147Glutamatergic signaling between neurons and oligodendrocyte lineage cells: Is it synaptic or non-synaptic?
Q48600994Juvenile striatal white matter is resistant to ischemia-induced damage
Q35995980Myelin Proteolipid Protein Complexes with αv Integrin and AMPA Receptors In Vivo and Regulates AMPA-Dependent Oligodendrocyte Progenitor Cell Migration through the Modulation of Cell-Surface GluR2 Expression
Q38631729Vasa Recta Pericyte Density is Negatively Associated with Vascular Congestion in the Renal Medulla Following Ischemia Reperfusion in Rats

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