A comparison of cell-cycle markers in skull base and sacral chordomas

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A comparison of cell-cycle markers in skull base and sacral chordomas is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.WNEU.2013.01.131
P698PubMed publication ID23416769

P50authorYasin TemelQ28839725
Ali JahanshahiQ64995250
P2093author name stringRuth Fleischeuer
David Creytens
Youssef Yakkioui
Jacobus J Van Overbeeke
René G C Santegoeds
P2860cites workInteraction between Cdc37 and Cdk4 in human cellsQ24321275
Potential therapeutic targets for chordoma: PI3K/AKT/TSC1/TSC2/mTOR pathwayQ24648029
Frequent deletion of the CDKN2A locus in chordoma: analysis of chromosomal imbalances using array comparative genomic hybridisationQ24651310
Crystal structure of human CDK4 in complex with a D-type cyclinQ24656160
Live or let die: the cell's response to p53Q29547663
Cancer. p53, guardian of the genomeQ29615610
Functional interactions of the retinoblastoma protein with mammalian D-type cyclinsQ29618856
Prognostic factors in chordoma of the sacrum and mobile spine: a study of 39 patientsQ33270830
Skull base chordomas: correlation of tumour doubling time with age, mitosis and Ki67 proliferation indexQ33270925
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Chordoma: review of clinicoradiological features and factors affecting survivalQ33271158
Apoptotic and proliferative markers in chordomas: a study of 26 tumorsQ33271245
Skull base and nonskull base chordomas: clinicopathologic and immunohistochemical study with special reference to nuclear pleomorphism and proliferative abilityQ33271977
Alterations of G1-S checkpoint in chordoma: the prognostic impact of p53 overexpressionQ33272380
Chordomas of the base of the skull and upper cervical spine. One hundred patients irradiated by a 3D conformal technique combining photon and proton beamsQ33272423
Chordomas of the skull base: follow-up review and prognostic factorsQ33272570
Analysis of immunohistochemical expression of p53 and the proliferation marker Ki-67 antigen in skull base chordomas: relationships between their expression and prognosisQ33273006
Proton therapy in chordoma of the base of the skull: a systematic reviewQ33273341
Adjuvant radiation therapy and chondroid chordoma subtype are associated with a lower tumor recurrence rate of cranial chordomaQ33273597
Methylthioadenosine phosphorylase and activated insulin-like growth factor-1 receptor/insulin receptor: potential therapeutic targets in chordoma.Q33273688
Loss of SMARCB1/INI1 expression in poorly differentiated chordomasQ33273964
Chordoma: role of radiation therapyQ33276967
Chordoma and chondroid neoplasms of the spheno-occiput: An immunohistochemical study of 41 cases with prognostic and nosologic implicationsQ33278408
Base of skull chordoma. A correlative study of histologic and clinical features of 62 casesQ33278482
Chordomas of the mediastinum: clinicopathologic, immunohistochemical, and ultrastructural study of six cases presenting as posterior mediastinal massesQ33278670
Proliferative activities in conventional chordoma: a clinicopathologic, DNA flow cytometric, and immunohistochemical analysis of 17 specimens with special reference to anaplastic chordoma showing a diffuse proliferation and nuclear atypiaQ33278726
Chordoma: long-term follow-up after radical photon irradiationQ33278855
Immunohistochemical examination of proliferative potentials and the expression of cell cycle-related proteins of intracranial chordomasQ33278919
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The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressorQ34030117
Structure of an Hsp90-Cdc37-Cdk4 complex.Q34562863
Central chondrosarcoma progression is associated with pRb pathway alterations: CDK4 down-regulation and p16 overexpression inhibit cell growth in vitroQ35841926
Therapeutic targets in the ARF tumor suppressor pathway.Q36879301
CDK4 inhibitors and apoptosis: a novel mechanism requiring nucleolar targeting of RelA.Q40128010
Docking-dependent regulation of the Rb tumor suppressor protein by Cdk4.Q40550671
Identification of a conserved sequence motif that promotes Cdc37 and cyclin D1 binding to Cdk4.Q40602791
Dissection of protein-protein interaction and CDK4 inhibition in the oncogenic versus tumor suppressing functions of gankyrin and P16.Q41982097
Phosphorylation of p16INK4A correlates with Cdk4 associationQ44279182
Melanoma cells can tolerate high levels of transcriptionally active endogenous p53 but are sensitive to retrovirus-transduced p53.Q45864245
Cyclin-dependent kinases regulate the antiproliferative function of SmadsQ47229633
Promoter hypermethylation and homozygous deletion of the p14ARF and p16INK4a genes in oligodendrogliomas.Q55474435
p53-dependent repression of CDK4 translation in TGF-beta-induced G1 cell-cycle arrestQ72534970
ChordomaQ74039855
p53 Stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation productsQ74183048
The over-expression of p53 H179Y residue mutation causes the increase of cyclin A1 and Cdk4 expression in HELF cellsQ80387675
P433issue1-2
P921main subjectchordomaQ1076389
base of skullQ1423729
P304page(s)e311-8
P577publication date2013-02-14
P1433published inWorld NeurosurgeryQ26853866
P1476titleA comparison of cell-cycle markers in skull base and sacral chordomas
P478volume82

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cites work (P2860)
Q47384424CDK4 expression in chordoma: A potential therapeutic target
Q33275783Chordoma: an update on the pathophysiology and molecular mechanisms
Q41184358EGFR Inhibition in a Pretreated Sacral Chordoma: A Role for Erlotinib? Case Report and a Brief Review of Literature
Q50128933Immunophenotypic features of dedifferentiated skull base chordoma: An insight into the intratumoural heterogeneity
Q33275755In chordoma, metastasis, recurrences, Ki-67 index, and a matrix-poor phenotype are associated with patients' shorter overall survival
Q50988142Ki-67 Index as a Prognostic Marker in Chordomas: A Systematic Review of the Literature.
Q33275854Prognostic and Therapeutic Markers in Chordomas: A Study of 287 Tumors
Q98184286Synergistic drug combinations and machine learning for drug repurposing in chordoma
Q92559641The clinical outcomes for chordomas in the cranial base and spine: A single center experience
Q33275745The molecular aspects of chordoma

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