The over-expression of p53 H179Y residue mutation causes the increase of cyclin A1 and Cdk4 expression in HELF cells

scientific article published on 26 May 2007

The over-expression of p53 H179Y residue mutation causes the increase of cyclin A1 and Cdk4 expression in HELF cells is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1034086881
P356DOI10.1007/S11010-007-9503-9
P698PubMed publication ID17530187

P2093author name stringJie Gao
Xi Jin
Qian Chen
Zhiqin Wang
Di Yang
Zongcan Zhou
Juanling Fu
Xilong Xiao
Yitao Qi
P2860cites workMutations in the p53 gene in primary human breast cancersQ68321480
Wild-type human p53 activates the human epidermal growth factor receptor promoterQ72351836
NMR spectroscopy reveals the solution dimerization interface of p53 core domains bound to their consensus DNAQ74631439
Cyclin A1 is a p53-induced gene that mediates apoptosis, G2/M arrest, and mitotic catastrophe in renal, ovarian, and lung carcinoma cellsQ79787890
The effects of a mutant p53 protein on the proliferation and differentiation of PC12 rat phaeochromocytoma cellsQ79830553
Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulationQ24301892
Cytoplasmic p53 polypeptide is associated with ribosomesQ24646226
p53 inhibits RNA polymerase III-directed transcription in a promoter-dependent mannerQ24647526
Surfing the p53 networkQ28032484
Definition of a consensus binding site for p53Q28207794
Oncogenic forms of p53 inhibit p53-regulated gene expressionQ28251120
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p53 mutations in human cancersQ28302973
Cyclins and cancer. II: Cyclin D and CDK inhibitors come of ageQ29618409
p53: death starQ34103258
Regulation of cyclin E transcription by E2Fs and retinoblastoma proteinQ34382483
The effects of wild-type p53 tumor suppressor activity and mutant p53 gain-of-function on cell growthQ34402080
Cyclin A1, the alternative A-type cyclin, contributes to G1/S cell cycle progression in somatic cellsQ34411420
p53 function and dysfunctionQ35721291
p53 mutation heterogeneity in cancerQ36113160
The p53 tumour suppressor geneQ37751892
Mutant human tumor suppressor p53 modulates the activation of mitogen-activated protein kinase and nuclear factor-kappaB, but not c-Jun N-terminal kinase and activated protein-1.Q38319170
DNA binding specificity of proteins derived from alternatively spliced mouse p53 mRNAsQ38347516
Induction of cell apoptosis in non-small cell lung cancer cells by cyclin A1 small interfering RNA.Q38508706
Mutant p53 in MDA-MB-231 breast cancer cells is stabilized by elevated phospholipase D activity and contributes to survival signals generated by phospholipase D.Q40265316
Mutant p53 induces the GEF-H1 oncogene, a guanine nucleotide exchange factor-H1 for RhoA, resulting in accelerated cell proliferation in tumor cellsQ40266928
Modulation of cellular and viral promoters by mutant human p53 proteins found in tumor cellsQ40281014
Modulation of gene expression by tumor-derived p53 mutantsQ40502644
A transcriptionally active DNA-binding site for human p53 protein complexesQ40655196
A novel p53 mutant retained functional activity in lung carcinomas.Q40679879
Synergistic action of Drosophila cyclins A and B during the G2-M transitionQ40871675
Changes in p53 expression can modify cell shape of ras-transformed fibroblasts and epitheliocytes.Q41073633
A codon 248 p53 mutation retains tumor suppressor function as shown by enhancement of tumor growth by antisense p53.Q41527846
p53 is covalently linked to 5.8S rRNA.Q41595909
Modulation of activity of the promoter of the human MDR1 gene by Ras and p53.Q41643433
p53 is a general repressor of RNA polymerase III transcriptionQ42645736
The p53 codon 249 mutant--derived from human functional adrenal tumors--can modify the cell shape of normal adrenocortical transfected cellsQ43670487
Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replicationQ44703400
Mutant p53 gain of function: the NF-Y connection.Q53600645
Wild-type p53 activates transcription in vitroQ59054260
Correlation between the expression of cyclin A protein and p53 activity in oral squamous cell carcinomasQ59317430
Mutant p53 proteins bind DNA abnormally in vitroQ67912813
P433issue1-2
P304page(s)219-226
P577publication date2007-05-26
P1433published inMolecular and Cellular BiochemistryQ1573176
P1476titleThe over-expression of p53 H179Y residue mutation causes the increase of cyclin A1 and Cdk4 expression in HELF cells
P478volume304

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