| Q36713868 | A Dynamical Framework for the All-or-None G1/S Transition. |
| Q49914149 | A Precise Cdk Activity Threshold Determines Passage through the Restriction Point. |
| Q33889698 | A novel function of adenovirus E1A is required to overcome growth arrest by the CDK2 inhibitor p27(Kip1). |
| Q36255082 | A requirement for cyclin D3-cyclin-dependent kinase (cdk)-4 assembly in the cyclic adenosine monophosphate-dependent proliferation of thyrocytes |
| Q39459140 | Accumulation of cyclin E is not a prerequisite for passage through the restriction point |
| Q36324624 | Activation of retinoblastoma protein in mammary gland leads to ductal growth suppression, precocious differentiation, and adenocarcinoma |
| Q40018751 | Adenovirus E1B55K region is required to enhance cyclin E expression for efficient viral DNA replication. |
| Q98159042 | Ailanthone: A novel potential drug for treating human cancer |
| Q40715541 | An E2F-binding site mediates the activation of the proliferative isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase by phosphatidylinositol 3-kinase |
| Q37970290 | An integrated view of cyclin E function and regulation |
| Q24554436 | CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase |
| Q33608768 | Cell cycle control, checkpoint mechanisms, and genotoxic stress |
| Q39578269 | Cell cycle dysregulation by human cytomegalovirus: influence of the cell cycle phase at the time of infection and effects on cyclin transcription. |
| Q35774769 | Cell cycle inhibition by the anti-angiogenic agent TNP-470 is mediated by p53 and p21WAF1/CIP1 |
| Q38125405 | Cell cycle regulation during neurogenesis in the embryonic and adult brain |
| Q28346664 | Cell cycle-dependent recruitment of HDAC-1 correlates with deacetylation of histone H4 on an Rb-E2F target promoter |
| Q24522801 | Cell cycle-regulated expression of mammalian CDC6 is dependent on E2F. |
| Q24306110 | Cellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcription |
| Q35037230 | Coactivator-associated arginine methyltransferase 1 (CARM1) is a positive regulator of the Cyclin E1 gene |
| Q37362758 | Combination of autophagy inducer rapamycin and oncolytic adenovirus improves antitumor effect in cancer cells |
| Q28506695 | Constitutive turnover of cyclin E by Cul3 maintains quiescence |
| Q39446523 | Critical role played by cyclin D3 in the MyoD-mediated arrest of cell cycle during myoblast differentiation |
| Q22010574 | Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells |
| Q33887377 | Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins. |
| Q41897660 | Cyclin E and chromosome instability in colorectal cancer cell lines |
| Q39575492 | Cyclin E associates with components of the pre-mRNA splicing machinery in mammalian cells |
| Q36720967 | Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo. |
| Q34069083 | Disruption of the G1/S transition in human papillomavirus type 16 E7-expressing human cells is associated with altered regulation of cyclin E |
| Q64900392 | Down-regulation of CCNE1 expression suppresses cell proliferation and sensitizes gastric carcinoma cells to Cisplatin. |
| Q33803614 | Dysregulation of cyclin E gene expression in human cytomegalovirus-infected cells requires viral early gene expression and is associated with changes in the Rb-related protein p130. |
| Q33890848 | E2F mediates developmental and cell cycle regulation of ORC1 in Drosophila |
| Q39235418 | E2F-2 Promotes Nuclear Condensation and Enucleation of Terminally Differentiated Erythroblasts |
| Q35057036 | Early growth response (EGR)-1 is required for timely cell-cycle entry and progression in hepatocytes after acute carbon tetrachloride exposure in mice. |
| Q33599528 | Endogenous E2F-1 promotes timely G0 exit of resting mouse embryo fibroblasts |
| Q36387370 | Enhanced cancer cell killing by truncated E2F-1 used in combination with oncolytic adenovirus. |
| Q27692024 | Examination of the expanding pathways for the regulation of p21 expression and activity |
| Q39549997 | Expression of EBNA-1 mRNA is regulated by cell cycle during Epstein-Barr virus type I latency. |
| Q33949158 | Expression of cyclins E1 and E2 during mouse development and in neoplasia |
| Q35787939 | Expression of p27(kip) and other cell cycle regulators in malignant peripheral nerve sheath tumors and neurofibromas: the emerging role of p27(kip) in malignant transformation of neurofibromas |
| Q36611467 | Expression of thymidylate synthase in human cells is an early G(1) event regulated by CDK4 and p16INK4A but not E2F. |
| Q39574223 | Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes |
| Q33285000 | Fundamental differences in cell cycle deregulation in human papillomavirus-positive and human papillomavirus-negative head/neck and cervical cancers |
| Q34317041 | G1 arrest and differentiation can occur independently of Rb family function |
| Q38290455 | Gene expression changes in response to E2F1 activation. |
| Q36138397 | Histone Deacetylation of RB-Responsive Promoters: Requisite for Specific Gene Repression but Dispensable for Cell Cycle Inhibition |
| Q37377351 | Human papillomavirus 16 E7 inactivator of retinoblastoma family proteins complements human cytomegalovirus lacking UL97 protein kinase. |
| Q28647319 | Identification of a substrate-targeting domain in cyclin E necessary for phosphorylation of the retinoblastoma protein |
| Q36224734 | Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53. |
| Q37256512 | Increased histone H1 phosphorylation and relaxed chromatin structure in Rb-deficient fibroblasts |
| Q39878682 | Induction of cyclins E and A in response to mitogen removal: a basic alteration associated with the arrest of differentiation of C2 myoblasts transformed by simian virus 40 large T antigen |
| Q35879549 | Induction of p53-independent growth inhibition in lung carcinoma cell A549 by gypenosides |
| Q39880567 | Infection of primary cells by adeno-associated virus type 2 results in a modulation of cell cycle-regulating proteins |
| Q35206804 | Inhibition of DNA synthesis by RB: effects on G1/S transition and S-phase progression |
| Q33890290 | Integration of a growth-suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor |
| Q39452818 | Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway |
| Q35139294 | Kaposi's sarcoma-associated herpesvirus LANA-1 interacts with the short variant of BRD4 and releases cells from a BRD4- and BRD2/RING3-induced G1 cell cycle arrest |
| Q28975623 | Kelch Repeat and BTB Domain Containing Protein 5 (Kbtbd5) Regulates Skeletal Muscle Myogenesis through the E2F1-DP1 Complex |
| Q34408376 | Krüppel-like factor 4 prevents centrosome amplification following gamma-irradiation-induced DNA damage |
| Q34220979 | LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis, and associates with the activated b-Raf-ERK1/2-mTOR pathway in breast cancer patients |
| Q40079322 | Loss of Emi1-dependent anaphase-promoting complex/cyclosome inhibition deregulates E2F target expression and elicits DNA damage-induced senescence. |
| Q36850367 | Lysine acetyltransferase GCN5 potentiates the growth of non-small cell lung cancer via promotion of E2F1, cyclin D1, and cyclin E1 expression |
| Q39406924 | MYC Modulation around the CDK2/p27/SKP2 Axis |
| Q28475455 | Mammalian MCM loading in late-G(1) coincides with Rb hyperphosphorylation and the transition to post-transcriptional control of progression into S-phase |
| Q89379344 | Measuring cell cycle-dependent DNA damage responses and p53 regulation on a cell-by-cell basis from image analysis |
| Q27021818 | Mitotic and mitogenic Wnt signalling |
| Q33967106 | Multifaceted regulation of cell cycle progression by estrogen: regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 function |
| Q34151707 | Murine coronavirus replication induces cell cycle arrest in G0/G1 phase. |
| Q35187372 | Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcriptional program |
| Q37002726 | Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer |
| Q24533583 | Mutations of the Drosophila dDP, dE2F, and cyclin E genes reveal distinct roles for the E2F-DP transcription factor and cyclin E during the G1-S transition. |
| Q35973957 | MyoD-dependent regulation of NF-κB activity couples cell-cycle withdrawal to myogenic differentiation |
| Q24684949 | NPAT expression is regulated by E2F and is essential for cell cycle progression |
| Q24536288 | Negative regulation of nuclear divisions in Caenorhabditis elegans by retinoblastoma and RNA interference-related genes |
| Q24522638 | Negative regulation of transcription by the type II arginine methyltransferase PRMT5 |
| Q50093673 | NeoPalAna: Neoadjuvant Palbociclib, a Cyclin-Dependent Kinase 4/6 Inhibitor, and Anastrozole for Clinical Stage 2 or 3 Estrogen Receptor-Positive Breast Cancer |
| Q33855990 | Novel splice variants of cyclin E with altered substrate specificity |
| Q35497058 | Nuclear localization of γ-tubulin affects E2F transcriptional activity and S-phase progression |
| Q36065105 | Nucleolar GTP-binding Protein-1 (NGP-1) Promotes G1 to S Phase Transition by Activating Cyclin-dependent Kinase Inhibitor p21 Cip1/Waf1. |
| Q35193528 | ORC localization in Drosophila follicle cells and the effects of mutations in dE2F and dDP. |
| Q37180412 | Opposing roles for DNA replication initiator proteins ORC1 and CDC6 in control of Cyclin E gene transcription |
| Q42818392 | Overexpression of phosphatidylinositol synthase enhances growth and G1 progression in NIH3T3 cells |
| Q47435142 | PTEN Physically Interacts with and Regulates E2F1-mediated Transcription in Lung Cancer. |
| Q36567545 | Position-dependent transcriptional regulation of the murine dihydrofolate reductase promoter by the E2F transactivation domain |
| Q39137425 | Proliferative effects of excretory/secretory products from Clonorchis sinensis on the human epithelial cell line HEK293 via regulation of the transcription factor E2F1. |
| Q40876356 | Ras and signal transducer and activator of transcription (STAT) are essential and sufficient downstream components of Janus kinases in cell proliferation |
| Q89565649 | Regulation of cyclin E1 expression in human pluripotent stem cells and derived neural progeny |
| Q33781529 | Regulation of exit from quiescence by p27 and cyclin D1-CDK4. |
| Q38054735 | Regulation of the g1/s transition in hepatocytes: involvement of the cyclin-dependent kinase cdk1 in the DNA replication |
| Q33818658 | Repression of Epstein-Barr virus EBNA-1 gene transcription by pRb during restricted latency |
| Q28647334 | Retinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexes |
| Q39673795 | Retinoblastoma protein transcriptional repression through histone deacetylation of a single nucleosome |
| Q37260877 | Role of E2F1-cyclin E1-cyclin E2 circuit in human coronary smooth muscle cell proliferation and therapeutic potential of its downregulation by siRNAs. |
| Q36178123 | Role of PP2Calpha in cell growth, in radio- and chemosensitivity, and in tumorigenicity |
| Q33965546 | Role of the LXCXE binding site in Rb function |
| Q52566582 | SALL2 represses cyclins D1 and E1 expression, and restrains G1/S cell cycle transition and cancer-related phenotypes. |
| Q39149962 | SATB1 collaborates with loss of p16 in cellular transformation |
| Q33958506 | Serum-induced expression of the cdc25A gene by relief of E2F-mediated repression |
| Q36626696 | Signaling pathways that control cell proliferation. |
| Q39457123 | Sonic hedgehog promotes G(1) cyclin expression and sustained cell cycle progression in mammalian neuronal precursors |
| Q35187190 | Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth |
| Q33781802 | Strain-dependent myeloid hyperplasia, growth deficiency, and accelerated cell cycle in mice lacking the Rb-related p107 gene. |
| Q41526922 | Strategies for Approaching Retinoblastoma Tumor Suppressor Gene Therapy |
| Q36573886 | Subunit composition determines E2F DNA-binding site specificity |
| Q40242882 | TGF beta-induced growth inhibition in primary fibroblasts requires the retinoblastoma protein |
| Q34305647 | The Nuclear Matrix Protein, NRP/B, Acts as a Transcriptional Repressor of E2F-mediated Transcriptional Activity |
| Q28854377 | The PR/SET domain zinc finger protein Prdm4 regulates gene expression in embryonic stem cells but plays a nonessential role in the developing mouse embryo |
| Q33825170 | The cancer/testis antigen CAGE with oncogenic potential stimulates cell proliferation by up-regulating cyclins D1 and E in an AP-1- and E2F-dependent manner |
| Q39721972 | The differential binding of E2F and CDF repressor complexes contributes to the timing of cell cycle-regulated transcription |
| Q39714707 | The human cytomegalovirus immediate early 2 protein dissociates cellular DNA synthesis from cyclin-dependent kinase activation |
| Q37157234 | The interaction of the gammaherpesvirus 68 orf73 protein with cellular BET proteins affects the activation of cell cycle promoters |
| Q44872415 | The kinetic origins of the restriction point in the mammalian cell cycle. |
| Q80387675 | The over-expression of p53 H179Y residue mutation causes the increase of cyclin A1 and Cdk4 expression in HELF cells |
| Q36321919 | The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E. |
| Q57538318 | The plant cell cycle in context |
| Q43085896 | The products of the herpes simplex virus type 1 immediate-early US1/US1.5 genes downregulate levels of S-phase-specific cyclins and facilitate virus replication in S-phase Vero cells |
| Q39473621 | The retinoblastoma gene Rb and its family member p130 suppress lung adenocarcinoma induced by oncogenic K-Ras. |
| Q38087182 | The ubiquitin proteasome system - implications for cell cycle control and the targeted treatment of cancer |
| Q36086767 | The ubiquitin-specific protease USP7 modulates the replication of Kaposi's sarcoma-associated herpesvirus latent episomal DNA |
| Q33890688 | Timing of cyclin E gene expression depends on the regulated association of a bipartite repressor element with a novel E2F complex. |
| Q33969505 | Tumor-specific proteolytic processing of cyclin E generates hyperactive lower-molecular-weight forms |
| Q52678203 | USP27-mediated Cyclin E stabilization drives cell cycle progression and hepatocellular tumorigenesis. |
| Q35173653 | Up-regulation of cyclin E in breast cancer via estrogen receptor pathway |
| Q35058583 | Virotherapy targeting cyclin E overexpression in tumors with adenovirus-enhanced cancer-selective promoter |
| Q39554010 | c-ETS1 facilitates G1/S-phase transition by up-regulating cyclin E and CDK2 genes and cooperates with hepatitis B virus X protein for their deregulation |
| Q33958488 | c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points |
| Q33842575 | p21cip1 Degradation in differentiated keratinocytes is abrogated by costabilization with cyclin E induced by human papillomavirus E7. |
| Q28395949 | p65 Negatively regulates transcription of the cyclin E gene |