Adenovirus E1B55K region is required to enhance cyclin E expression for efficient viral DNA replication.

scientific article published on 30 January 2008

Adenovirus E1B55K region is required to enhance cyclin E expression for efficient viral DNA replication. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.01708-07
P8608Fatcat IDrelease_crvzxluj7vdpbnfnpxrydhalaq
P932PMC publication ID2268468
P698PubMed publication ID18234796

P50authorJorge G Gomez-GutierrezQ79690709
Kelly M. McMastersQ55615790
Xinyu ZhengQ56995221
P2093author name stringH Sam Zhou
Hongying Hao
Xiao-Mei Rao
P2860cites workKinase-independent function of cyclin EQ79544656
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p53 status does not determine outcome of E1B 55-kilodalton mutant adenovirus lytic infectionQ33785919
Recombinant, replication-defective adenovirus gene transfer vectors induce cell cycle dysregulation and inappropriate expression of cyclin proteins.Q33785925
p53-Independent and -dependent requirements for E1B-55K in adenovirus type 5 replicationQ33814900
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S-phase induction by adenovirus E1A requires activation of cdc25a tyrosine phosphatase.Q44789824
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Adenovirus with insertion-mutated E1A selectively propagates in liver cancer cells and destroys tumors in vivo.Q45862986
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Domains required for in vitro association between the cellular p53 and the adenovirus 2 E1B 55K proteins.Q53503674
Cyclin E is a more powerful predictor of breast cancer outcome than proliferationQ58188808
Gene expression profiles of normal human lung cells affected by adenoviral E1BQ64377980
E1A-induced apoptosis does not prevent replication of adenoviruses with deletion of E1b in majority of infected cancer cellsQ64379383
E1A modulates phosphorylation of p130 and p107 by differentially regulating the activity of G1/S cyclin/CDK complexesQ64379575
Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibitionQ77310904
Stable association of mitotic cyclin B/Cdc2 to replication origins prevents endoreduplicationQ78482184
Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfectionQ34562704
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From ONYX-015 to armed vaccinia viruses: the education and evolution of oncolytic virus developmentQ34577135
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Adenovirus E1A targets key regulators of cell proliferationQ35260997
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Cyclin E.Q35775507
The early region 1B 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycleQ35875344
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The adenovirus E4orf6 protein can promote E1A/E1B-induced focus formation by interfering with p53 tumor suppressor functionQ35991794
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Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cellsQ36246072
p21 and retinoblastoma protein control the absence of DNA replication in terminally differentiated muscle cellsQ36328385
Cyclin e overexpression reduces infiltrative growth in breast cancer: yet another link between proliferation control and tumor invasionQ36438500
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The adenovirus E1B-55K transforming polypeptide modulates transport or cytoplasmic stabilization of viral and host cell mRNAsQ36909556
Adenovirus type 5 early region 1b gene product is required for efficient shutoff of host protein synthesis.Q36914451
E1B 55-kilodalton oncoproteins of adenovirus types 5 and 12 inactivate and relocalize p53, but not p51 or p73, and cooperate with E4orf6 proteins to destabilize p53.Q38317803
The zinc finger transcription factor ZFHX1A is linked to cell proliferation by Rb-E2F1.Q39254725
E2F transcriptional repressor complexes are critical downstream targets of p19(ARF)/p53-induced proliferative arrestQ39404546
Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathwayQ39452818
Replication of ONYX-015, a potential anticancer adenovirus, is independent of p53 status in tumor cells.Q39582723
Analyses of single-amino-acid substitution mutants of adenovirus type 5 E1B-55K proteinQ39602482
Activation of Adenovirus Early Promoters and Lytic Phase in Differentiated Strata of Organotypic Cultures of Human KeratinocytesQ39752580
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Adenovirus type 5 E1A gene therapy for ovarian clear cell carcinoma: a potential treatment strategy.Q40184003
Selective replication of E1B55K-deleted adenoviruses depends on enhanced E1A expression in cancer cells.Q40341364
Adenoviral E1a expression levels affect virus-selective replication in human cancer cellsQ40362547
Viral oncoprotein binding to pRB, p107, p130, and p300.Q40532162
E1B-55-kilodalton protein is not required to block p53-induced transcription during adenovirus infectionQ40541104
Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53.Q40736238
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Processing of cyclin E differs between normal and tumor breast cellsQ40900933
Enhanced expression of p53 in human cells infected with mutant adenovirusesQ41444438
Characterization of the 55K adenovirus type 5 E1B product and related proteinsQ41475587
Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible systemQ41483751
Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.Q41563742
Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosisQ41563751
Role of the Rb/E2F pathway in cell growth controlQ41640467
Viral transactivating proteinsQ41689449
Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: a novel mechanism for E1A trans-activationQ41724590
Adenovirus type 5 early region 1B 156R protein promotes cell transformation independently of repression of p53-stimulated transcriptionQ41786916
Structure and transcription of human papillomavirus sequences in cervical carcinoma cellsQ41914039
Cdc42 promotes G1 progression through p70 S6 kinase-mediated induction of cyclin E expressionQ42169248
A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting.Q42639115
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectAdenoviridaeQ193447
P304page(s)3415-3427
P577publication date2008-01-30
P1433published inJournal of VirologyQ1251128
P1476titleAdenovirus E1B55K region is required to enhance cyclin E expression for efficient viral DNA replication
P478volume82

Reverse relations

cites work (P2860)
Q28477181A dynamical systems model for combinatorial cancer therapy enhances oncolytic adenovirus efficacy by MEK-inhibition
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