Cyclin E dysregulation and chromosomal instability in endometrial cancer

scientific article published in May 2004

Cyclin E dysregulation and chromosomal instability in endometrial cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/SJ.ONC.1207560
P8608Fatcat IDrelease_efely3dv3jcndccevyegp4reru
P698PubMed publication ID15048079
P5875ResearchGate publication ID8652912

P50authorAndreas WidschwendterQ115512994
Andreas GschwendtnerQ71921278
Elisabeth Müller-HolznerQ115512993
P2093author name stringSteven I Reed
Martin Widschwendter
Charles H Spruck
Christian Marth
Hannes M Müller
Georg Goebel
Martin Erdel
Heidi M Fiegl
Michael M Hubalek
P2860cites workCyclin-dependent kinase control of centrosome duplicationQ24673544
Cyclin E and survival in patients with breast cancerQ27824788
Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell linesQ28188140
Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell lineQ28188152
Distinct roles for cyclins E and A during DNA replication complex assembly and activationQ28206467
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligaseQ28215069
DNA copy number losses in human neoplasmsQ33733232
Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycleQ34076834
Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin EQ36564958
Malignant transformation by cyclin E and Ha-Ras correlates with lower sensitivity towards induction of cell death but requires functional Myc and CDK4.Q41076718
Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible systemQ41483751
Deregulated cyclin E induces chromosome instabilityQ41692394
Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylationQ42809976
Fourth updated ESACP consensus report on diagnostic DNA image cytometry.Q52044386
DNA amplifications and aneuploidy, high proliferative activity and impaired cell cycle control characterize breast carcinomas with poor prognosis.Q54560489
P433issue23
P407language of work or nameEnglishQ1860
P304page(s)4187-4192
P577publication date2004-05-01
P1433published inOncogeneQ1568657
P1476titleCyclin E dysregulation and chromosomal instability in endometrial cancer
P478volume23

Reverse relations

cites work (P2860)
Q36848850A jekyll and hyde role of cyclin E in the genotoxic stress response: switching from cell cycle control to apoptosis regulation
Q80608586Aberrant expression of cell cycle regulators in Hodgkin and Reed-Sternberg cells of classical Hodgkin's lymphoma
Q40018751Adenovirus E1B55K region is required to enhance cyclin E expression for efficient viral DNA replication.
Q90411105CCND2 and CCND3 hijack immunoglobulin light-chain enhancers in cyclin D1- mantle cell lymphoma
Q37149363CENP-F expression is associated with poor prognosis and chromosomal instability in patients with primary breast cancer
Q30480596Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1).
Q36186117Cyclin-Dependent Kinase Inhibitors as Anticancer Therapeutics
Q83919587Deregulated cyclin E promotes p53 loss of heterozygosity and tumorigenesis in the mouse mammary gland
Q37151091Dual CCNE1/PIK3CA targeting is synergistic in CCNE1-amplified/PIK3CA-mutated uterine serous carcinomas in vitro and in vivo
Q33564004Evidence for a p27 tumor suppressive function independent of its role regulating cell proliferation in the prostate
Q44825377Expression of cyclin A, cyclin E and p27 in normal, hyperplastic and frankly malignant endometrial samples
Q29616127FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation
Q27852932FBXW7 mutations in patients with advanced cancers: clinical and molecular characteristics and outcomes with mTOR inhibitors
Q58797685FBXW7: a critical tumor suppressor of human cancers
Q46661944Fbw7 regulates the activity of endoreduplication mediators and the p53 pathway to prevent drug-induced polyploidy.
Q24310626Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver
Q49477276Fbxw7 regulates renal cell carcinoma migration and invasion via suppression of the epithelial-mesenchymal transition
Q40417959Infrequent mutations of Archipelago (hAGO, hCDC4, Fbw7) in primary ovarian cancer
Q34389043MiR-495 regulates proliferation and migration in NSCLC by targeting MTA3.
Q37216927NFAT1 transcription factor regulates cell cycle progression and cyclin E expression in B lymphocytes
Q35006035Overexpression of TROP2 predicts poor prognosis of patients with cervical cancer and promotes the proliferation and invasion of cervical cancer cells by regulating ERK signaling pathway
Q33892360Ras activity regulates cyclin E degradation by the Fbw7 pathway.
Q24307181The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7

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