Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing

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Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing is …
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scholarly articleQ13442814

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P356DOI10.1101/GAD.443107
P932PMC publication ID2000321
P698PubMed publication ID17901217
P5875ResearchGate publication ID5943980

P50authorPeer BorkQ7160367
Elisa IzaurraldeQ1329654
Silke DornerQ21264663
Jan RehwinkelQ28152068
Eric HuntzingerQ63132686
Ana EulalioQ28480607
Tobias DoerksQ30002515
P2093author name stringMichael Boutros
Schu-Fee Yang
Mona Stricker
P2860cites workTranslation repression in human cells by microRNA-induced gene silencing requires RCK/p54Q21146051
Identification of novel argonaute-associated proteinsQ24295156
Multiple processing body factors and the ARE binding protein TTP activate mRNA decappingQ24299303
An mRNA m7G cap binding-like motif within human Ago2 represses translationQ24306727
Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free systemQ24328771
A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencingQ24537488
miRNP:mRNA association in polyribosomes in a human neuronal cell line.Q24537541
MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail functionQ24538996
mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexesQ24554481
Identification of many microRNAs that copurify with polyribosomes in mammalian neuronsQ24630366
A role for the P-body component GW182 in microRNA functionQ24669847
MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodiesQ24681266
Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain proteinQ24810079
Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cellsQ24810080
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
MicroRNA silencing through RISC recruitment of eIF6Q28118262
The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translationQ28143010
Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A.Q43559954
Evidence that microRNAs are associated with translating messenger RNAs in human cellsQ45345564
The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegansQ47068671
Drosophila miR2 induces pseudo-polysomes and inhibits translation initiation.Q52679873
MicroRNA Inhibition of Translation Initiation in Vitro by Targeting the Cap-Binding Complex eIF4FQ58880697
Release of eIF6 (p27BBP) from the 60S subunit allows 80S ribosome assemblyQ28189135
WD-repeat proteins: structure characteristics, biological function, and their involvement in human diseasesQ28216786
Relief of microRNA-mediated translational repression in human cells subjected to stressQ28246349
Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodiesQ28252216
Inhibition of translational initiation by Let-7 MicroRNA in human cellsQ28265842
Regulation by let-7 and lin-4 miRNAs results in target mRNA degradationQ28268899
P bodies: at the crossroads of post-transcriptional pathwaysQ28280058
Disruption of GW bodies impairs mammalian RNA interferenceQ28281500
Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAsQ29547837
MicroRNAs direct rapid deadenylation of mRNAQ29614566
Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolutionQ29616370
The enzymes and control of eukaryotic mRNA turnoverQ29616563
Repression of protein synthesis by miRNAs: how many mechanisms?Q29620361
Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granulesQ30479192
An RNA interference screen identifies Inhibitor of Apoptosis Protein 2 as a regulator of innate immune signalling in Drosophila.Q33223553
VARICOSE, a WD-domain protein, is required for leaf blade developmentQ33339458
Genome-wide RNAi analysis of growth and viability in Drosophila cellsQ34295039
Ge-1 is a central component of the mammalian cytoplasmic mRNA processing bodyQ34366701
Eukaryotic protein synthesis inhibitors identified by comparison of cytotoxicity profilesQ34366957
Short RNAs repress translation after initiation in mammalian cells.Q34495292
How do microRNAs regulate gene expression?Q34573729
Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430.Q34579220
Arabidopsis DCP2, DCP1, and VARICOSE form a decapping complex required for postembryonic developmentQ34589416
Substrate selectivity of exportin 5 and Dicer in the biogenesis of microRNAsQ34611663
Formation of GW bodies is a consequence of microRNA genesisQ35016215
Bringing the role of mRNA decay in the control of gene expression into focusQ35885699
Mechanisms of microRNA-mediated gene regulation in animal cellsQ36763232
MicroRNAs silence gene expression by repressing protein expression and/or by promoting mRNA decay.Q36768214
Human let-7a miRNA blocks protein production on actively translating polyribosomesQ40204130
Genome-wide analysis of mRNAs regulated by Drosha and Argonaute proteins in Drosophila melanogasterQ41986263
P-body formation is a consequence, not the cause, of RNA-mediated gene silencingQ42738042
P433issue20
P407language of work or nameEnglishQ1860
P921main subjectgene silencingQ1431332
Ge-1 Dmel_CG6181Q29810539
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)2558-2570
P577publication date2007-09-27
P1433published inGenes & DevelopmentQ1524533
P1476titleTarget-specific requirements for enhancers of decapping in miRNA-mediated gene silencing
P478volume21

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