mtDNA nt13708A variant increases the risk of multiple sclerosis

scientific article

mtDNA nt13708A variant increases the risk of multiple sclerosis is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2008PLoSO...3.1530Y
P356DOI10.1371/JOURNAL.PONE.0001530
P932PMC publication ID2217590
P698PubMed publication ID18270557
P5875ResearchGate publication ID5580675

P50authorKjell-Morten MyhrQ64539690
Sverre J MörkQ117803414
Janna SaarelaQ30501405
Joerg T. EpplenQ41713571
Maria Giovanna MarrosuQ42408301
Saleh IbrahimQ43139623
P2093author name stringDirk Koczan
Anna-Maija Sulonen
Manuel Comabella
Xavier Montalban
Denis A Akkad
Peter Rieckmann
Gianna Costa
Xinhua Yu
Antje Kroner
Daniela Corongiu
Hans-Juergen Thiesen
Harald I Nyland
Montserrat Camina-Tato
Robert Goertsches
P2860cites workParent-child concordance in multiple sclerosisQ70174854
Regional and temporal variation in the incidence of multiple sclerosis in Finland 1979-1993Q73473404
Mitochondrial DNA mutations in multiple sclerosisQ73822072
mtDNA haplogroup J: a contributing factor of optic neuritisQ77421708
Is the mitochondrial DNA involved in determining susceptibility to multiple sclerosis?Q77530983
Large scale screening of the mitochondrial DNA reveals no pathogenic mutations but a haplotype associated with multiple sclerosis in CaucasiansQ77926568
Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common diseaseQ22337234
Classification of European mtDNAs from an analysis of three European populationsQ24533221
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species productionQ28139177
Mitochondrial DNA inherited variants are associated with successful aging and longevity in humansQ28143058
Mitochondrial DNA polymorphisms associated with longevity in a Finnish populationQ28217719
Alternative, simultaneous complex I mitochondrial DNA mutations in Leber's hereditary optic neuropathyQ28300484
mtDNA and the origin of Caucasians: identification of ancient Caucasian-specific haplogroups, one of which is prone to a recurrent somatic duplication in the D-loop regionQ28762142
Mitochondrial Polymorphisms Significantly Reduce the Risk of Parkinson DiseaseQ29398392
New diagnostic criteria for multiple sclerosis: guidelines for research protocolsQ34271601
Mitochondrial defects in neurodegenerative diseaseQ34366678
Mitochondrial DNA and human evolution.Q34560425
Uncoupling protein 2 has protective function during experimental autoimmune encephalomyelitis.Q35088315
Haplotype and phylogenetic analyses suggest that one European-specific mtDNA background plays a role in the expression of Leber hereditary optic neuropathy by increasing the penetrance of the primary mutations 11778 and 14484.Q35238441
mtDNA mutations and common neurodegenerative disordersQ36254228
LEBER'S DISEASE WITH SYMPTOMS RESEMBLING DISSEMINATED SCLEROSISQ37119019
Impairment of central and peripheral myelin in mitochondrial diseasesQ41378824
The power to detect disease associations with mitochondrial DNA haplogroupsQ43259568
Mitochondrial DNA variants in Bulgarian patients affected by multiple sclerosisQ43928632
Leber's hereditary optic neuropathy mitochondrial DNA mutations in multiple sclerosisQ44557768
Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in FinnsQ46687091
Analysis of Genetic Variation in the GenomEUtwin ProjectQ47377818
Population screening for association of mitochondrial haplogroups BM, J, K and M with multiple sclerosis: interrelation between haplogroup J and MS in Persian patients.Q51312107
Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patientsQ53206553
'Secondary' 4216/ND1 and 13708/ND5 Leber's hereditary optic neuropathy mitochondrial DNA mutations do not further impair in vivo mitochondrial oxidative metabolism when associated with the 11778/ND4 mitochondrial DNA mutationQ57009422
Parent-of-origin effect in multiple sclerosis: observations in half-siblingsQ57317733
Evidence from mtDNA sequences that common laboratory strains of inbred mice are descended from a single femaleQ59071263
Association of a common polymorphism in the promoter of UCP2 with susceptibility to multiple sclerosisQ60689182
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectmultiple sclerosisQ8277
P304page(s)e1530
P577publication date2008-02-13
P1433published inPLOS OneQ564954
P1476titlemtDNA nt13708A variant increases the risk of multiple sclerosis
P478volume3

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cites work (P2860)
Q47959866Association of UCP2 -866 G/A polymorphism with chronic inflammatory diseases
Q36311088Clinically proven mtDNA mutations are not common in those with chronic fatigue syndrome.
Q37034596Dissecting the effects of mtDNA variations on complex traits using mouse conplastic strains.
Q91672723Four novel mutations in the mitochondrial ND4 gene of complex I in patients with multiple sclerosis
Q46270458Generation and Bioenergetic Profiles of Cybrids with East Asian mtDNA Haplogroups
Q37466077Is multiple sclerosis a mitochondrial disease?
Q24600533May "mitochondrial eve" and mitochondrial haplogroups play a role in neurodegeneration and Alzheimer's disease?
Q51840198Mitochondrial DNA polymorphisms are associated with susceptibility and phenotype of systemic lupus erythematosus
Q28710285Mitochondrial DNA sequence variation and neurodegeneration
Q41844017Mitochondrial DNA sequence variation in multiple sclerosis.
Q91982232Mitochondrial Dysfunction and Multiple Sclerosis
Q46646521Mitochondrial gene polymorphism is associated with gut microbial communities in mice
Q38908404MtDNA T4216C variation in multiple sclerosis: a systematic review and meta-analysis
Q64098211MtDNA population variation in Myalgic encephalomyelitis/Chronic fatigue syndrome in two populations: a study of mildly deleterious variants
Q38106595Multiple sclerosis and mitochondrial gene variations: A review
Q33942825Mutational analysis of whole mitochondrial DNA in patients with MELAS and MERRF diseases
Q54274045Polymorphisms in the mitochondrially encoded ATP synthase 8 gene are associated with susceptibility to bullous pemphigoid in the German population.
Q34544496Principal-component analysis for assessment of population stratification in mitochondrial medical genetics
Q37862835Role of gender in multiple sclerosis: Clinical effects and potential molecular mechanisms
Q34390958Sex-specific regulation of mitochondrial DNA levels: genome-wide linkage analysis to identify quantitative trait loci
Q39161650Stressed cybrids model demyelinated axons in multiple sclerosis.
Q92454632The second genome: Effects of the mitochondrial genome on cancer progression
Q58122630mtDNA Population Variants and Neurodegenerative Diseases

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