| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1017098107 |
| P356 | DOI | 10.1186/1471-2261-8-9 |
| P932 | PMC publication ID | 2387135 |
| P698 | PubMed publication ID | 18447926 |
| P5875 | ResearchGate publication ID | 5404392 |
| P2093 | author name string | Frank C Brosius | |
| Henry M Rosevear | |||
| Ricky Malhotra | |||
| David W Tyson | |||
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| Activation of the prolyl hydroxylase oxygen-sensor results in induction of GLUT1, heme oxygenase-1, and nitric-oxide synthase proteins and confers protection from metabolic inhibition to cardiomyocytes | Q44370245 | ||
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| Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury | Q44915260 | ||
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| Functionality of hypoxia-induced BAX expression in a human glioblastoma xenograft model | Q45881209 | ||
| Evidence of HIF-1 functional binding activity to caspase-3 promoter after photothrombotic cerebral ischemia | Q48371823 | ||
| c-Myc sensitization to oxygen deprivation-induced cell death is dependent on Bax/Bak, but is independent of p53 and hypoxia-inducible factor-1. | Q51642930 | ||
| Oxidized low-density lipoprotein stimulates p53-dependent activation of proapoptotic Bax leading to apoptosis of differentiated endothelial progenitor cells | Q64377254 | ||
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| Expression of constitutively stable hybrid hypoxia-inducible factor-1alpha protects cultured rat cardiomyocytes against simulated ischemia-reperfusion injury | Q64379241 | ||
| Reperfusion injury on cardiac myocytes after simulated ischemia | Q71897464 | ||
| Hypoxia-inducible factor 1: master regulator of O2 homeostasis | Q77485489 | ||
| High glucose concentrations alter hypoxia-induced control of vascular smooth muscle cell growth via a HIF-1alpha-dependent pathway | Q79828891 | ||
| Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension | Q24307473 | ||
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| Direct interactions between HIF-1 alpha and Mdm2 modulate p53 function | Q28212296 | ||
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| Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis | Q28279053 | ||
| Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1 | Q28282227 | ||
| Role of hypoxia-inducible factor-1alpha in hypoxia-induced apoptosis of primary alveolar epithelial type II cells | Q28571969 | ||
| Glucose uptake and adenoviral mediated GLUT1 infection decrease hypoxia-induced HIF-1alpha levels in cardiac myocytes | Q28583255 | ||
| The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis | Q28591257 | ||
| Rational siRNA design for RNA interference | Q29614450 | ||
| Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing | Q29617570 | ||
| A trip to the ER: coping with stress | Q29620455 | ||
| HIF hydroxylation and cellular oxygen sensing | Q30164092 | ||
| Glucose uptake and glycolysis reduce hypoxia-induced apoptosis in cultured neonatal rat cardiac myocytes | Q33178140 | ||
| Bcl-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death | Q34290708 | ||
| Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology | Q34343405 | ||
| Transcriptional and translational control in the Mammalian unfolded protein response | Q34762452 | ||
| Is HIF-1alpha a pro- or an anti-apoptotic protein? | Q34816112 | ||
| Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation | Q35120687 | ||
| Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia | Q35195197 | ||
| Delayed adaptation of the heart to stress: late preconditioning | Q35622774 | ||
| Heart mitochondria signaling pathways: appraisal of an emerging field | Q35819361 | ||
| A unique pathway of cardiac myocyte death caused by hypoxia-acidosis. | Q35858005 | ||
| The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis | Q35903445 | ||
| HIF-1alpha activation by a redox-sensitive pathway mediates cyanide-induced BNIP3 upregulation and mitochondrial-dependent cell death | Q36102779 | ||
| Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival | Q36549632 | ||
| Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance | Q37011260 | ||
| HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. | Q38296946 | ||
| Hypoxia induces apoptosis in SV40-immortalized rat proximal tubular cells through the mitochondrial pathways, devoid of HIF1-mediated upregulation of Bax. | Q38351071 | ||
| Inhibition of hypoxia inducible factor 1alpha causes oxygen-independent cytotoxicity and induces p53 independent apoptosis in glioblastoma cells | Q38357282 | ||
| CoCl2, a chemical inducer of hypoxia-inducible factor-1, and hypoxia reduce apoptotic cell death in hepatoma cell line HepG2. | Q40683109 | ||
| Dominant-negative hypoxia-inducible factor-1 alpha reduces tumorigenicity of pancreatic cancer cells through the suppression of glucose metabolism | Q41857469 | ||
| P275 | copyright license | Creative Commons Attribution 2.0 Generic | Q19125117 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P921 | main subject | hypoxia | Q105688 |
| P304 | page(s) | 9 | |
| P577 | publication date | 2008-04-30 | |
| P1433 | published in | BMC Cardiovascular Disorders | Q15753126 |
| P1476 | title | Hypoxia-inducible factor-1alpha is a critical mediator of hypoxia induced apoptosis in cardiac H9c2 and kidney epithelial HK-2 cells | |
| P478 | volume | 8 |
| Q38819738 | An RNA interference screen identifies new avenues for nephroprotection |
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| Q35173596 | Disruption of hypoxia-inducible transcription factor-prolyl hydroxylase domain-1 (PHD-1-/-) attenuates ex vivo myocardial ischemia/reperfusion injury through hypoxia-inducible factor-1α transcription factor and its target genes in mice. |
| Q36138944 | Easy-to-use strategy for reference gene selection in quantitative real-time PCR experiments. |
| Q89482306 | Effects of normoxic and hypoxic exercise training on the bactericidal capacity and subsequent apoptosis of neutrophils in sedentary men |
| Q48004345 | Engineered myocardium model to study the roles of HIF-1α and HIF1A-AS1 in paracrine-only signaling under pathological level oxidative stress |
| Q28580076 | Mild hypoxia-induced cardiomyocyte hypertrophy via up-regulation of HIF-1α-mediated TRPC signalling |
| Q90318889 | Proximal Tubular Development Is Impaired with Downregulation of MAPK/ERK Signaling, HIF-1α, and Catalase by Hyperoxia Exposure in Neonatal Rats |
| Q34097528 | Retinoblastoma binding protein 2 (RBP2) promotes HIF-1α-VEGF-induced angiogenesis of non-small cell lung cancer via the Akt pathway |
| Q36993250 | Role of hypoxia-inducible factor 1 alpha in the integrity of articular cartilage in murine knee joints |
| Q39570726 | Small interfering RNA targeting HIF-1α reduces hypoxia-dependent transcription and radiosensitizes hypoxic HT 1080 human fibrosarcoma cells in vitro |
| Q45915558 | Systemic hypoxia enhances exercise-mediated bactericidal and subsequent apoptotic responses in human neutrophils. |
| Q34696040 | The G protein-coupled receptor 30 is up-regulated by hypoxia-inducible factor-1alpha (HIF-1alpha) in breast cancer cells and cardiomyocytes |
| Q33815579 | The cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor α-mediated signaling in cancer cells and in cardiomyocytes |
| Q53666709 | Transactivation of EGFR by prostaglandin E2 receptors: a nuclear story? |
| Q47096955 | miR-210 Protects Renal Cell Against Hypoxia-induced Apoptosis by Targeting HIF-1 Alpha |
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