A trip to the ER: coping with stress

scientific article (publication date: 2004)

A trip to the ER: coping with stress is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.TCB.2003.11.001
P3181OpenCitations bibliographic resource ID765807
P698PubMed publication ID14729177
P5875ResearchGate publication ID8441755

P50authorThomas RutkowskiQ73255638
P2093author name stringRandal J Kaufman
P2860cites workCaspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-betaQ22011091
Regulated translation initiation controls stress-induced gene expression in mammalian cellsQ28506388
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)20-28
P577publication date2004-01-01
P1433published inTrends in Cell BiologyQ1573994
P1476titleA trip to the ER: coping with stress
P478volume14

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cites work (P2860)
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Q47449487Endoplasmic reticulum stress inhibits expression of genes involved in thyroid hormone synthesis and their key transcriptional regulators in FRTL-5 thyrocytes.
Q64238732Endoplasmic reticulum stress markers are of no value in predicting cardiopulmonary resuscitation success and survival in out-of hospital cardiac arrest: A nested case-control study
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Q39848302Endoplasmic reticulum stress response as a potential therapeutic target in multiple sclerosis
Q42094437Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2
Q34637782Endoplasmic reticulum stress signaling is involved in mitomycin C (MMC)-induced apoptosis in human fibroblasts via PERK pathway
Q40421732Endoplasmic reticulum stress signaling transmitted by ATF6 mediates apoptosis during muscle development
Q45152588Endoplasmic reticulum stress stimulates heme oxygenase-1 gene expression in vascular smooth muscle. Role in cell survival
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Q53325918Equine endometrial gene expression changes during and after maternal recognition of pregnancy.
Q41969044Escherichia coli O157:H7 suppresses host autophagy and promotes epithelial adhesion via Tir-mediated and cAMP-independent activation of protein kinase A
Q33403626Eukaryotic protein production in designed storage organelles
Q54542095Evidence of endoplasmic reticulum stress mediating cell death in transplanted human islets.
Q48571255Evidence of the activation of unfolded protein response in granulosa and cumulus cells during follicular growth and maturation.
Q39533279Excessive fluoride induces endoplasmic reticulum stress and interferes enamel proteinases secretion
Q26801783Experimental Evidence Shows Salubrinal, an eIF2α Dephosphorylation Inhibitor, Reduces Xenotoxicant-Induced Cellular Damage
Q35601541Experimental evidence for therapeutic potential of taurine in the treatment of nonalcoholic fatty liver disease
Q39619556Exploring the influence of torsinA expression on protein quality control
Q33668770Expression and function of HSP110 family in mouse testis after vasectomy
Q35986635Expression of XBP1s in bone marrow stromal cells is critical for myeloma cell growth and osteoclast formation
Q40195451Expression of human coagulation factor VIII in a human hybrid cell line, HKB11.
Q36483972Expression of murine leukemia virus envelope protein is sufficient for the induction of apoptosis
Q48480386Extended liver resection after preoperative chemotherapy: influence on regeneration and endoplasmic reticulum stress response
Q40021459Fatty acid-mediated endoplasmic reticulum stress in vivo: differential response to the infusion of Soybean and Lard Oil in rats
Q33624864Fisetin Protects PC12 Cells from Tunicamycin-Mediated Cell Death via Reactive Oxygen Species Scavenging and Modulation of Nrf2-Driven Gene Expression, SIRT1 and MAPK Signaling in PC12 Cells
Q27477652Flavivirus Infection Activates the XBP1 Pathway of the Unfolded Protein Response To Cope with Endoplasmic Reticulum Stress
Q35129210Fluoride's effects on the formation of teeth and bones, and the influence of genetics
Q50713890Freedom of expression. Focus on "Endoplasmic reticulum stress and the unfolded protein response regulate cystic fibrosis transmembrane conductance regulator expression".
Q39140456Frog virus 3 open reading frame 97R localizes to the endoplasmic reticulum and induces nuclear invaginations
Q36362397From acute ER stress to physiological roles of the Unfolded Protein Response
Q34116716Functional RNA interference (RNAi) screen identifies system A neutral amino acid transporter 2 (SNAT2) as a mediator of arsenic-induced endoplasmic reticulum stress
Q38102949Functional and morphological impact of ER stress on mitochondria
Q36836856Functional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells.
Q33962565Functional processing and secretion of Chikungunya virus E1 and E2 glycoproteins in insect cells
Q64298513G-Protein-Coupled Receptor 120 Mediates DHA-Induced Apoptosis by Regulating IP3R, ROS and, ER Stress Levels in Cisplatin-Resistant Cancer Cells
Q37106828GNRH induces the unfolded protein response in the LbetaT2 pituitary gonadotrope cell line
Q92104918GRP78 Level Is Altered in the Brain, but Not in Plasma or Cerebrospinal Fluid in Parkinson's Disease Patients
Q24302321GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis
Q36615162GRP78 plays an essential role in adipogenesis and postnatal growth in mice
Q64060447GRP78/BIP/HSPA5 as a Therapeutic Target in Models of Parkinson's Disease: A Mini Review
Q36170215GRP78/BiP is a novel downstream target of IGF-1 receptor mediated signaling
Q38886485GSK-3β-dependent downregulation of γ-taxilin and αNAC merge to regulate ER stress responses
Q42768469Gadolinium-induced oxidative stress triggers endoplasmic reticulum stress in rat cortical neurons
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Q41114641Gene expression in primary cultured astrocytes affected by aluminum: alteration of chaperons involved in protein folding
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Q37429250Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB.
Q46924484Glucosamine-induced Sp1 O-GlcNAcylation ameliorates hypoxia-induced SGLT dysfunction in primary cultured renal proximal tubule cells
Q90414841Glucose-Regulated Protein 78 in the Aqueous Humor of Patients with Diabetic Macular Edema
Q40370849Glycogen synthase kinase 3beta modulates synphilin-1 ubiquitylation and cellular inclusion formation by SIAH: implications for proteasomal function and Lewy body formation.
Q39621569Glycogen synthase kinase-3 (GSK-3) inhibition attenuates hepatocyte lipoapoptosis
Q26801535Glycoprotein Quality Control and Endoplasmic Reticulum Stress
Q48109062Golgi-mediated vacuolar sorting of the endoplasmic reticulum chaperone BiP may play an active role in quality control within the secretory pathway
Q42583843Good fat, essential cellular requirements for triacylglycerol synthesis to maintain membrane homeostasis in yeast
Q33836210Grandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal muscle
Q33619491Group VIA phospholipase A2 mitigates palmitate-induced β-cell mitochondrial injury and apoptosis
Q33556664Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance
Q35180639Guanabenz interferes with ER stress and exerts protective effects in cardiac myocytes
Q26992217Guards and culprits in the endoplasmic reticulum: glucolipotoxicity and β-cell failure in type II diabetes
Q50866059HMGB1 induces endothelial progenitor cells apoptosis via RAGE-dependent PERK/eIF2α pathway.
Q58416239HSP-4 endoplasmic reticulum (ER) stress pathway is not activated in a C. elegans model of ethanol intoxication and withdrawal
Q36402063HSP105 interacts with GRP78 and GSK3 and promotes ER stress-induced caspase-3 activation
Q41821383HacA-independent induction of chaperone-encoding gene bipA in Aspergillus niger strains overproducing membrane proteins
Q42501673Hepatic BSCL2 (Seipin) Deficiency Disrupts Lipid Droplet Homeostasis and Increases Lipid Metabolism via SCD1 Activity.
Q84008571Hepatic PTP1B Deficiency: The Promise of a Treatment for Metabolic Syndrome?
Q40210691Hepatitis B virus X protein (HBx) activates ATF6 and IRE1-XBP1 pathways of unfolded protein response
Q34797179Hepatitis C virus NS2 protein triggers endoplasmic reticulum stress and suppresses its own viral replication
Q34542590Hepatitis C virus nonstructural protein 5A inhibits thapsigargin-induced apoptosis
Q34568352Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner
Q35617662High-Density Lipoprotein Prevents Endoplasmic Reticulum Stress-Induced Downregulation of Liver LOX-1 Expression
Q51034395High-level extracellular production of glucose oxidase by recombinant Pichia pastoris using a combined strategy.
Q45285244Homocysteine down-regulates cellular glutathione peroxidase (GPx1) by decreasing translation
Q46126818Homocysteine-induced endoplasmic reticulum protein (Herp) is up-regulated in sporadic inclusion-body myositis and in endoplasmic reticulum stress-induced cultured human muscle fibers
Q36627066Hormetic effects of acute methylmercury exposure on grp78 expression in rat brain cortex
Q38770536Host glycosylation pathways and the unfolded protein response contribute to the infection by Francisella
Q48287722Host response to intravenous injection of epsilon toxin in mouse model: a proteomic view
Q27469611Human cytomegalovirus infection activates and regulates the unfolded protein response
Q40458981Human cytomegalovirus protein US11 provokes an unfolded protein response that may facilitate the degradation of class I major histocompatibility complex products
Q36423955Human cytomegalovirus specifically controls the levels of the endoplasmic reticulum chaperone BiP/GRP78, which is required for virion assembly
Q34529775Human homologs of Ubc6p ubiquitin-conjugating enzyme and phosphorylation of HsUbc6e in response to endoplasmic reticulum stress
Q33331198Hypoxia-inducible factor-1alpha is a critical mediator of hypoxia induced apoptosis in cardiac H9c2 and kidney epithelial HK-2 cells
Q39119944Hypoxia-triggered m-calpain activation evokes endoplasmic reticulum stress and neuropathogenesis in a transgenic mouse model of Alzheimer's disease.
Q46182848IL-1beta caused pancreatic beta-cells apoptosis is mediated in part by endoplasmic reticulum stress via the induction of endoplasmic reticulum Ca2+ release through the c-Jun N-terminal kinase pathway
Q38347956IRE1alpha controls cyclin A1 expression and promotes cell proliferation through XBP-1.
Q52649161Identification and Characterization of Maize floury4 as a Novel Semidominant Opaque Mutant That Disrupts Protein Body Assembly.
Q36642753Identification of ERp29 as a biomarker for predicting nasopharyngeal carcinoma response to radiotherapy
Q34402836Identification of an old antibiotic clofoctol as a novel activator of unfolded protein response pathways and an inhibitor of prostate cancer
Q37375524Identification of novel pepper genes involved in Bax- or INF1-mediated cell death responses by high-throughput virus-induced gene silencing
Q34756838Identification of small molecules that protect pancreatic β cells against endoplasmic reticulum stress-induced cell death
Q34757824Identification of stromal differentially expressed proteins in the colon carcinoma by quantitative proteomics
Q37108439Immunity to viruses: learning from successful human vaccines
Q50034063Impact of Arginine to Cysteine Mutations in Collagen II on Protein Secretion and Cell Survival
Q39264714Impaired endoplasmic reticulum stress response in bipolar disorder: cellular evidence of illness progression
Q38089906Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part I: targeting p53, Mdm2, GADD153/CHOP, GRP78/BiP and heat shock proteins
Q34589523Improving yeast strains using recyclable integration cassettes, for the production of plant terpenoids
Q37394440In vitro reconstitution of ER-stress induced ATF6 transport in COPII vesicles
Q35011096In vivo crystallization of human IgG in the endoplasmic reticulum of engineered Chinese hamster ovary (CHO) cells.
Q40321831In vivo regulation of Grp78/BiP transcription in the embryonic heart: role of the endoplasmic reticulum stress response element and GATA-4.
Q42396896Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophages
Q36061450Increased sensitivity to glucose starvation correlates with downregulation of glycogen phosphorylase isoform PYGB in tumor cell lines resistant to 2-deoxy-D-glucose
Q35563335Induction of ER stress-mediated apoptosis by ceramide via disruption of ER Ca(2+) homeostasis in human adenoid cystic carcinoma cells
Q35785377Induction of endoplasmic reticulum stress in thymic lymphocytes by the envelope precursor polyprotein of a murine leukemia virus during the preleukemic period
Q40254780Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1.
Q46257956Infectious Agents in Atherosclerotic Cardiovascular Diseases through Oxidative Stress.
Q35762999Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway.
Q38771484Inherent ER stress in pancreatic islet β cells causes self-recognition by autoreactive T cells in type 1 diabetes
Q92699242Inhibition of TRIB3 Protects Against Neurotoxic Injury Induced by Kainic Acid in Rats
Q93242538Inhibition of endoplasmic reticulum stress protected DOCA-salt hypertension-induced vascular dysfunction
Q33291107Inhibition of proliferation by PERK regulates mammary acinar morphogenesis and tumor formation
Q87682822Inhibition of transient receptor potential melastatin 7 (TRPM7) channel induces RA FLSs apoptosis through endoplasmic reticulum (ER) stress
Q37635791Inositol-requiring enzyme 1 inhibits respiratory syncytial virus replication
Q82505664Interaction between endoplasmic reticulum stress and caspase 8 activation in retrovirus MoMuLV-ts1-infected astrocytes
Q33684606Interactive Toxicogenomics: Gene set discovery, clustering and analysis in Toxygates
Q28575443Interferon-gamma potentiates endoplasmic reticulum stress-induced death by reducing pancreatic beta cell defence mechanisms
Q34027764Interferon-γ inhibits central nervous system myelination through both STAT1-dependent and STAT1-independent pathways
Q37229342Intracellular death platform steps-in: targeting prostate tumors via endoplasmic reticulum (ER) apoptosis
Q37112649Intracellular devastation in heart failure
Q34698161Intrinsic capacities of molecular sensors of the unfolded protein response to sense alternate forms of endoplasmic reticulum stress
Q28552468Introgression of opaque2 into Waxy Maize Causes Extensive Biochemical and Proteomic Changes in Endosperm
Q35060167Investigation of protein secretion and secretion stress in Ashbya gossypii
Q40346054Involvement of endoplasmic reticulum stress in hereditary tyrosinemia type I.
Q37364081Involvement of voltage-dependent anion channel (VDAC) in dengue infection
Q37268106Ischemic tolerance as an active and intrinsic neuroprotective mechanism
Q24655066Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis
Q48525288Juvenile hormone differentially regulates two Grp78 genes encoding protein chaperones required for insect fat body cell homeostasis and vitellogenesis
Q46599445Kex1 protease is involved in yeast cell death induced by defective N-glycosylation, acetic acid, and chronological aging
Q39023988Knockdown of glucose-regulated protein 78 abrogates chemoresistance of hypopharyngeal carcinoma cells to cisplatin induced by unfolded protein in response to severe hypoxia
Q34764338Lipopolysaccharide preconditioning protects hepatocytes from ischemia/reperfusion injury (IRI) through inhibiting ATF4-CHOP pathway in mice
Q33333134Loss of p24 function in Drosophila melanogaster causes a stress response and increased levels of NF-kappaB-regulated gene products
Q37258291Loss of parasympathetic innervation leads to sustained expression of pro-inflammatory genes in the rat lacrimal gland
Q24300509Luman is capable of binding and activating transcription from the unfolded protein response element
Q24301000Luman/CREB3 induces transcription of the endoplasmic reticulum (ER) stress response protein Herp through an ER stress response element
Q35667423Luteolin and Apigenin Attenuate 4-Hydroxy-2-Nonenal-Mediated Cell Death through Modulation of UPR, Nrf2-ARE and MAPK Pathways in PC12 Cells
Q28386347Luteolin modulates 6-hydroxydopamine-induced transcriptional changes of stress response pathways in PC12 cells
Q36420160MLN4924, a Novel NEDD8-activating enzyme inhibitor, exhibits antitumor activity and enhances cisplatin-induced cytotoxicity in human cervical carcinoma: in vitro and in vivo study
Q52368866Mahanine drives pancreatic adenocarcinoma cells into endoplasmic reticular stress-mediated apoptosis through modulating sialylation process and Ca2+-signaling.
Q59791398Maternal Protein Restriction Induces Alterations in Hepatic Unfolded Protein Response-Related Molecules in Adult Rat Offspring
Q41598370Maternal obesity in mice not only affects fresh embryo quality but also aggravates injury due to vitrification
Q59330033Matrine attenuates endoplasmic reticulum stress and mitochondrion dysfunction in nonalcoholic fatty liver disease by regulating SERCA pathway
Q51647562Measurement of Calcium Fluctuations Within the Sarcoplasmic Reticulum of Cultured Smooth Muscle Cells Using FRET-based Confocal Imaging.
Q34574408Mechanism of arylating quinone toxicity involving Michael adduct formation and induction of endoplasmic reticulum stress
Q28478858Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling
Q88973517Mechanisms and context underlying the role of autophagy in cancer metastasis
Q36538348Mechanisms linking diabetes mellitus to the development of atherosclerosis: a role for endoplasmic reticulum stress and glycogen synthase kinase-3.
Q21710681Mechanisms of cell death in rhodopsin retinitis pigmentosa: implications for therapy
Q35132916Mechanisms of lipotoxicity in NAFLD and clinical implications
Q34986548Mechanisms of neuroprotection by protein disulphide isomerase in amyotrophic lateral sclerosis
Q37522775Mechanistic Study of Tetrahydrofuran- acetogenins In Triggering Endoplasmic Reticulum Stress Response-apotoposis in Human Nasopharyngeal Carcinoma
Q39733408Membrane chaperone Shr3 assists in folding amino acid permeases preventing precocious ERAD.
Q40984771Metabolically independent and accurately adjustable Aspergillus sp. expression system
Q43206333Metformin regulates palmitate-induced apoptosis and ER stress response in HepG2 liver cells
Q37583453Mink epithelial cell killing by pathogenic murine leukemia viruses involves endoplasmic reticulum stress
Q40116328Misfolded BRICHOS SP-C mutant proteins induce apoptosis via caspase-4- and cytochrome c-related mechanisms
Q35941821Misfolded proteins, endoplasmic reticulum stress and neurodegeneration
Q45253858Misfolding of collagen X chains harboring Schmid metaphyseal chondrodysplasia mutations results in aberrant disulfide bond formation, intracellular retention, and activation of the unfolded protein response
Q42864929Mitochondria maintain maturation and secretion of lipoprotein lipase in the endoplasmic reticulum
Q38270547Modeling protein misfolding in charcot-marie-tooth disease
Q40375854Modulating the endoplasmic reticulum stress response with trans-4,5-dihydroxy-1,2-dithiane prevents chemically induced renal injury in vivo
Q37577397Modulation of wolframin expression in human placenta during pregnancy: comparison among physiological and pathological states.
Q60910322Molecular and Functional Interaction of the Myokine Irisin with Physical Exercise and Alzheimer's Disease
Q24633202Molecular cross talk between misfolded proteins in animal models of Alzheimer's and prion diseases
Q38260582Molecular insights into the mechanisms of liver-associated diseases in early-lactating dairy cows: hypothetical role of endoplasmic reticulum stress
Q33963803Molecular symbiosis of CHOP and C/EBP beta isoform LIP contributes to endoplasmic reticulum stress-induced apoptosis
Q33791523Molecular targeting of proteins by L-homocysteine: mechanistic implications for vascular disease
Q34189696Morbillivirus glycoprotein expression induces ER stress, alters Ca2+ homeostasis and results in the release of vasostatin
Q45411188Mouse hepatitis virus infection activates the Ire1/XBP1 pathway of the unfolded protein response
Q38882139Mutations affecting the transmembrane domain of the LDL receptor: impact of charged residues on the membrane insertion.
Q36447981Mutations of the ELA2 gene found in patients with severe congenital neutropenia induce the unfolded protein response and cellular apoptosis
Q52659218Mycobacterium fortuitum-induced ER-Mitochondrial calcium dynamics promotes calpain/caspase-12/caspase-9 mediated apoptosis in fish macrophages.
Q34467234N-acetylcysteine attenuates reactive-oxygen-species-mediated endoplasmic reticulum stress during liver ischemia-reperfusion injury
Q88647924NGF Attenuates High Glucose-Induced ER Stress, Preventing Schwann Cell Apoptosis by Activating the PI3K/Akt/GSK3β and ERK1/2 Pathways
Q92431342Neuroligin-2-derived peptide-covered polyamidoamine-based (PAMAM) dendrimers enhance pancreatic β-cells' proliferation and functions
Q47786503Neuronal activity-dependent local activation of dendritic unfolded protein response promotes expression of brain-derived neurotrophic factor in cell soma.
Q35886625Neuronal cell death in neurodegenerative diseases: recurring themes around protein handling
Q38125218Neurotrophins, inflammation and oxidative stress as illness activity biomarkers in bipolar disorder
Q36831585Neutrophil-derived alpha defensins control inflammation by inhibiting macrophage mRNA translation
Q47812992New Aspects of the Contribution of ER to SOCE Regulation: The Role of the ER and ER-Plasma Membrane Junctions in the Regulation of SOCE.
Q30392273New Concepts in Alpha-1 Antitrypsin Deficiency Disease Mechanisms
Q46523776Nicotinic receptor activation contrasts pathophysiological bursting and neurodegeneration evoked by glutamate uptake block on rat hypoglossal motoneurons.
Q40518230Nitric Oxide and Protein Disulfide Isomerase Explain the Complexities of Unfolded Protein Response Following Intra-hippocampal Aβ Injection.
Q39321586Nitric oxide selectively depletes macrophages in atherosclerotic plaques via induction of endoplasmic reticulum stress
Q38304615Nodal signaling activates differentiation genes during zebrafish gastrulation
Q37088308Nogo-B Receptor Modulates Pulmonary Artery Smooth Muscle Cell Function in Developing Lungs
Q43820561NtbZIP60, an endoplasmic reticulum-localized transcription factor, plays a role in the defense response against bacterial pathogens in Nicotiana tabacum.
Q41050381Nupr1 Modulates Methamphetamine-Induced Dopaminergic Neuronal Apoptosis and Autophagy through CHOP-Trib3-Mediated Endoplasmic Reticulum Stress Signaling Pathway
Q37430909O-GlcNAc signaling attenuates ER stress-induced cardiomyocyte death.
Q37172898OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells
Q34323446Obesity has an interactive effect with genetic variation in the activating transcription factor 6 gene on the risk of pre-diabetes in individuals of Chinese Han descent
Q38943508Oncogenic BRAF induces chronic ER stress condition resulting in increased basal autophagy and apoptotic resistance of cutaneous melanoma
Q36575331Opposing roles of mitogenic and stress signaling pathways in the induction of cancer dormancy
Q37855346Organellar calcium buffers
Q53270191Organelle stress-induced activating transcription factor-3 downregulates low-density lipoprotein receptor expression in Sk-Hep1 human liver cells.
Q90349193OsDER1 Is an ER-Associated Protein Degradation Factor That Responds to ER Stress
Q37707655Osteopontin stimulates apoptosis in adult cardiac myocytes via the involvement of CD44 receptors, mitochondrial death pathway, and endoplasmic reticulum stress.
Q28248833Osteopontin: At the cross-roads of myocyte survival and myocardial function
Q39656899Over-expression of ERp29 attenuates doxorubicin-induced cell apoptosis through up-regulation of Hsp27 in breast cancer cells
Q58696971Overexpression of quality control proteins reduces prion conversion in prion-infected cells
Q55003322Oxaliplatin-induced blood brain barrier loosening: a new point of view on chemotherapy-induced neurotoxicity.
Q40229579Oxidative stress-triggered unfolded protein response is upstream of intrinsic cell death evoked by parkinsonian mimetics.
Q35903570Oxygen free radicals and redox biology of organelles
Q34980938Ozone inhalation modifies the rat liver proteome
Q33868451PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis
Q35192134PERK integrates autophagy and oxidative stress responses to promote survival during extracellular matrix detachment
Q58608809PIWI proteins contribute to apoptosis during the UPR in human airway epithelial cells
Q42293062PMP22 exon 4 deletion causes ER retention of PMP22 and a gain-of-function allele in CMT1E.
Q36072327PPARδ Activation Rescues Pancreatic β-Cell Line INS-1E from Palmitate-Induced Endoplasmic Reticulum Stress through Enhanced Fatty Acid Oxidation
Q34227880Palmitate induces mRNA translation and increases ER protein load in islet β-cells via activation of the mammalian target of rapamycin pathway
Q36402241Pathogen-endoplasmic-reticulum interactions: in through the out door
Q50014672Pharmacoperones as Novel Therapeutics for Diverse Protein Conformational Diseases
Q36609927Phellinus linteus activates different pathways to induce apoptosis in prostate cancer cells
Q28472833Phenylbutyric acid rescues endoplasmic reticulum stress-induced suppression of APP proteolysis and prevents apoptosis in neuronal cells
Q40232163Pin1 levels are downregulated during ER stress in human neuroblastoma cells.
Q37205061Polyamines: essential factors for growth and survival
Q65954080Polycystic Ovary Syndrome: Impact of Lipotoxicity on Metabolic and Reproductive Health
Q24318555Polycystin-2 down-regulates cell proliferation via promoting PERK-dependent phosphorylation of eIF2alpha
Q34581239Pontocerebellar hypoplasia type 2: a neuropathological update.
Q39014629Preferential cytotoxicity of the type I ribosome inactivating protein alpha-momorcharin on human nasopharyngeal carcinoma cells under normoxia and hypoxia.
Q37159445Pro370Leu mutant myocilin disturbs the endoplasm reticulum stress response and mitochondrial membrane potential in human trabecular meshwork cells.
Q82679783Processing of PLP in a model of Pelizaeus-Merzbacher disease/SPG2 due to the rumpshaker mutation
Q47295190Progesterone inhibited endoplasmic reticulum stress associated apoptosis induced by interleukin-1β via the GRP78/PERK/CHOP pathway in BeWo cells.
Q33778893Progressive renal injury from transgenic expression of human carbonic anhydrase IV folding mutants is enhanced by deficiency of p58IPK.
Q64951763Prolonged Exposure to Insulin Inactivates Akt and Erk1/2 and Increases Pancreatic Islet and INS1E β-Cell Apoptosis.
Q47799430Promotion of the Unfolding Protein Response in Orexin/Dynorphin Neurons in Sudden Infant Death Syndrome (SIDS): Elevated pPERK and ATF4 Expression.
Q24314837Protective effect against Parkinson's disease-related insults through the activation of XBP1
Q47220092Protein Localization at Mitochondria-ER Contact Sites in Basal and Stress Conditions.
Q35548395Protein aggregation of SERCA2 mutants associated with Darier disease elicits ER stress and apoptosis in keratinocytes
Q36085672Protein drug stability: a formulation challenge
Q26801543Protein kinase R-like ER kinase and its role in endoplasmic reticulum stress-decided cell fate
Q33267158Protein profiling of pancreatic islets
Q35948428Protein quality control mechanisms and protein storage in the endoplasmic reticulum. A conflict of interests?
Q28506667Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress
Q37320446Proteins altered by elevated levels of palmitate or glucose implicated in impaired glucose-stimulated insulin secretion
Q34109144Proteomic analysis of endothelial cold-adaptation
Q34341114Proteomic analysis reveals that pardaxin triggers apoptotic signaling pathways in human cervical carcinoma HeLa cells: cross talk among the UPR, c-Jun and ROS.
Q34317895Proteomic profiling of differentially expressed proteins from Bax inhibitor-1 knockout and wild type mice.
Q35469778Proteostasis regulation at the endoplasmic reticulum: a new perturbation site for targeted cancer therapy
Q45236966Protracted lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: roles of intracellular calcium, GRP78 and Bcl-2.
Q38868286Psychostimulant-Induced Endoplasmic Reticulum Stress and Neurodegeneration.
Q33392721Pyrvinium targets the unfolded protein response to hypoglycemia and its anti-tumor activity is enhanced by combination therapy
Q36096629Quantitative analyses of the hepatic proteome of methylmercury-exposed Atlantic cod (Gadus morhua) suggest oxidative stress-mediated effects on cellular energy metabolism
Q92217318Quantitative microscopy reveals dynamics and fate of clustered IRE1α
Q35896411ROS Accumulation by PEITC Selectively Kills Ovarian Cancer Cells via UPR-Mediated Apoptosis
Q48133993Rab6 is increased in Alzheimer's disease brain and correlates with endoplasmic reticulum stress
Q28577788Rapamycin inhibits postprandial-mediated X-box-binding protein-1 splicing in rat liver
Q52038310Rapid B cell receptor-induced unfolded protein response in nonsecretory B cells correlates with pro- versus antiapoptotic cell fate.
Q37015954Rationalizing translation attenuation in the network architecture of the unfolded protein response.
Q37802379Redox Balance in the Pathogenesis of Nonalcoholic Fatty Liver Disease: Mechanisms and Therapeutic Opportunities
Q93334728Redox signaling and unfolded protein response coordinate cell fate decisions under ER stress
Q24653736Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP
Q41874567Reducing TDP-43 aggregation does not prevent its cytotoxicity
Q24298269Regulation of AKT phosphorylation at Ser473 and Thr308 by endoplasmic reticulum stress modulates substrate specificity in a severity dependent manner
Q47446856Regulation of IRE1α by the small molecule inhibitor 4μ8c in hepatoma cells
Q28476029Regulation of PERK signaling and leukemic cell survival by a novel cytosolic isoform of the UPR regulator GRP78/BiP
Q36692569Regulation of autophagy during ECM detachment is linked to a selective inhibition of mTORC1 by PERK
Q47228609Regulation of gammaherpesvirus lytic replication by endoplasmic reticulum stress-induced transcription factors ATF4 and CHOP.
Q90588404Regulation of the adaptation to ER stress by KLF4 facilitates melanoma cell metastasis via upregulating NUCB2 expression
Q35280887Regulation of the death-associated protein kinase 1 expression and autophagy via ATF6 requires apoptosis signal-regulating kinase 1.
Q37423378Regulation of the unfolded protein response by microRNAs
Q34353513Reovirus induces and benefits from an integrated cellular stress response
Q92604878Repurposing Brigatinib for the Treatment of Colorectal Cancer Based on Inhibition of ER-phagy
Q93032872Restoration of skeletal muscle homeostasis by hydrogen sulfide during hyperhomocysteinemia-mediated oxidative/ER stress condition 1
Q79240845Retention of a bean phaseolin/maize gamma-Zein fusion in the endoplasmic reticulum depends on disulfide bond formation
Q36010989Reticulon Protein-1C: A New Hope in the Treatment of Different Neuronal Diseases
Q27935606Reticulons Regulate the ER Inheritance Block during ER Stress.
Q40246328Ribosomal stress couples the unfolded protein response to p53-dependent cell cycle arrest
Q37804627Role of Endoplasmic Reticulum Stress in Cystic Fibrosis-Related Airway Inflammatory Responses
Q64913707Role of Endoplasmic Reticulum Stress-Autophagy Axis in Severe Burn-Induced Intestinal Tight Junction Barrier Dysfunction in Mice.
Q37631563Role of IRE1α/XBP-1 in Cystic Fibrosis Airway Inflammation
Q37109991Role of MAPK in apolipoprotein CIII-induced apoptosis in INS-1E cells
Q38233882Role of endoplasmic reticulum stress in atherosclerosis and diabetic macrovascular complications
Q37976132Role of endoplasmic reticulum stress in metabolic disease and other disorders.
Q37899563Role of glucose-regulated Protein 78 in embryonic development and neurological disorders.
Q35831223Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease.
Q35435309Role of stress-activated MAP kinase P38 in cisplatin- and DTT-induced apoptosis of the esophageal carcinoma cell line Eca109.
Q42919393Role of the unfolded protein response regulator GRP78/BiP in development, cancer, and neurological disorders.
Q36497621Role of the unfolded protein response, GRP78 and GRP94 in organ homeostasis.
Q39227831Roles of Grp78 in Female Mammalian Reproduction
Q38961224Rotavirus infection induces the unfolded protein response of the cell and controls it through the nonstructural protein NSP3
Q34278554Rotavirus-host cell interactions: an arms race
Q41013060Rpl22 Loss Selectively Impairs αβ T Cell Development by Dysregulating Endoplasmic Reticulum Stress Signaling.
Q24338858SEPS1 protects RAW264.7 cells from pharmacological ER stress agent-induced apoptosis
Q34166885SERCaMP: a carboxy-terminal protein modification that enables monitoring of ER calcium homeostasis
Q88669930Salicylic acid-independent role of NPR1 is required for protection from proteotoxic stress in the plant endoplasmic reticulum
Q42871025Salt stress responses in Arabidopsis utilize a signal transduction pathway related to endoplasmic reticulum stress signaling
Q40139677Salt stress signaling in Arabidopsis thaliana involves a membrane-bound transcription factor AtbZIP17 as a signal transducer
Q34128069Saturated fatty acid induction of endoplasmic reticulum stress and apoptosis in human liver cells via the PERK/ATF4/CHOP signaling pathway
Q40147046Saturated fatty acid-mediated endoplasmic reticulum stress and apoptosis are augmented by trans-10, cis-12-conjugated linoleic acid in liver cells
Q41896082Schlafen2 mutation unravels a role for chronic ER stress in the loss of T cell quiescence
Q46417058Screening for mutants defective in secretory protein maturation and ER quality control
Q42483656Selective abrogation of BiP/GRP78 blunts activation of NF-κB through the ATF6 branch of the UPR: involvement of C/EBPβ and mTOR-dependent dephosphorylation of Akt.
Q39123489Selective, potent blockade of the IRE1 and ATF6 pathways by 4-phenylbutyric acid analogues
Q58611393Selenate Prevents Adipogenesis through Induction of Selenoprotein S and Attenuation of Endoplasmic Reticulum Stress
Q40051377Shiga toxin 1 induces apoptosis through the endoplasmic reticulum stress response in human monocytic cells
Q46806860Short-term overfeeding induces insulin resistance in weight-stable patients after bariatric surgery
Q35149248Sigma-1 receptor chaperones and diseases
Q39468102Silencing of glucose-regulated protein 78 (GRP78) enhances cell migration through the upregulation of vimentin in hepatocellular carcinoma cells.
Q41679204Silica nanoparticles induce endoplasmic reticulum stress response and activate mitogen activated kinase (MAPK) signalling
Q41680966Silica nanoparticles induce endoplasmic reticulum stress response, oxidative stress and activate the mitogen-activated protein kinase (MAPK) signaling pathway
Q36818022Similarities and differences in the pathogenesis of alcoholic and nonalcoholic steatohepatitis
Q24300776Simultaneous induction of the four subunits of the TRAP complex by ER stress accelerates ER degradation
Q30426463Single Prolonged Stress induces ATF6 alpha-dependent Endoplasmic reticulum stress and the apoptotic process in medial Frontal Cortex neurons
Q36321616Single, context-specific glycans can target misfolded glycoproteins for ER-associated degradation
Q34390829SirT3 regulates the mitochondrial unfolded protein response
Q27939329Specialized membrane-localized chaperones prevent aggregation of polytopic proteins in the ER.
Q47742080Sphingolipids activate the endoplasmic reticulum stress surveillance pathway.
Q34148249Stable ribosome binding to the endoplasmic reticulum enables compartment-specific regulation of mRNA translation
Q36440729Stimulation of N-linked glycosylation and lipid-linked oligosaccharide synthesis by stress responses in metazoan cells
Q26747461Stress Response and Translation Control in Rotavirus Infection
Q36210013Stress proteins in Alzheimer's disease.
Q28082709Stress responses from the endoplasmic reticulum in cancer
Q37915428Stress signaling from the endoplasmic reticulum: A central player in the pathogenesis of amyotrophic lateral sclerosis.
Q36514519Stress wars: the direct role of host and bacterial molecular chaperones in bacterial infection
Q36674827Stress, the endoplasmic reticulum, and insulin resistance
Q24321239Stress-induced ER to Golgi translocation of ceramide synthase 1 is dependent on proteasomal processing
Q36393488Stressing out the ER: a role of the unfolded protein response in prion-related disorders
Q36879894Studies in vitamin E: biochemistry and molecular biology of tocopherol quinones
Q33264756Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway
Q33749777Suppression of Hypoxia-Inducible Factor 1α (HIF-1α) by Tirapazamine Is Dependent on eIF2α Phosphorylation Rather Than the mTORC1/4E-BP1 Pathway
Q38834064Suppression of PKC causes oncogenic stress for triggering apoptosis in cancer cells
Q34594853Suppression of adipocyte differentiation by Cordyceps militaris through activation of the aryl hydrocarbon receptor
Q48231735Supra-pharmacological concentration of capsaicin stimulates brown adipogenesis through induction of endoplasmic reticulum stress
Q37086576Supreme EnLIGHTenment: damage recognition and signaling in the mammalian UV response
Q33273633Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function
Q99616701Synchrotron-based FTIR microspectroscopy of protein aggregation and lipids peroxidation changes in human cataractous lens epithelial cells
Q91713110Synergistic antitumor effect of 5-fluorouracil and withaferin-A induces endoplasmic reticulum stress-mediated autophagy and apoptosis in colorectal cancer cells
Q37072377Synoviolin, protein folding and the maintenance of joint homeostasis
Q37512024Synthetic embryonic lethality upon deletion of the ER cochaperone p58(IPK) and the ER stress sensor ATF6α
Q58698819Systemic signaling contributes to the unfolded protein response of the plant endoplasmic reticulum
Q64114418TRIB3 suppresses proliferation and invasion and promotes apoptosis of endometrial cancer cells by regulating the AKT signaling pathway
Q36368859Target of rapamycin signaling mediates vacuolar fission caused by endoplasmic reticulum stress in Saccharomyces cerevisiae
Q38019159Targeting Huntington's disease through histone deacetylases
Q42115123Targeting endoplasmic reticulum protein transport: a novel strategy to kill malignant B cells and overcome fludarabine resistance in CLL.
Q37774037Targeting histone deacetylases for the treatment of Huntington's disease.
Q37296159Targeting histone deacetylases for the treatment of disease
Q34082569Targets for cystic fibrosis therapy: proteomic analysis and correction of mutant cystic fibrosis transmembrane conductance regulator
Q37526157Tauroursodeoxycholic acid reduces ER stress by regulating of Akt-dependent cellular prion protein
Q42615665The 8ab protein of SARS-CoV is a luminal ER membrane-associated protein and induces the activation of ATF6.
Q41995694The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels
Q37336649The DNA virus white spot syndrome virus uses an internal ribosome entry site for translation of the highly expressed nonstructural protein ICP35.
Q42580374The ER Stress Surveillance (ERSU) pathway regulates daughter cell ER protein aggregate inheritance
Q46059743The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress
Q93078996The ER-localized Ca2+-binding protein calreticulin couples ER stress to autophagy by associating with microtubule-associated protein 1A/1B light chain 3
Q27026256The Endoplasmic Reticulum Chaperone GRP170: From Immunobiology to Cancer Therapeutics
Q35756951The HIV protease inhibitor nelfinavir downregulates Akt phosphorylation by inhibiting proteasomal activity and inducing the unfolded protein response
Q42728931The IRE1α-XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix
Q38113221The Molecular Chaperone GRP78/BiP as a Therapeutic Target for Neurodegenerative Disorders: A Mini Review
Q84963435The Origin and Role of MHC Class I-Associated Self-Peptides
Q26769783The Role of Endoplasmic Reticulum Stress and Unfolded Protein Response in Atherosclerosis
Q38507330The Role of Lectin-Carbohydrate Interactions in the Regulation of ER-Associated Protein Degradation.
Q28068986The Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress
Q27937897The Saccharomyces cerevisiae YFR041C/ERJ5 gene encoding a type I membrane protein with a J domain is required to preserve the folding capacity of the endoplasmic reticulum.
Q37711106The UPR and the anti-oxidant response: relevance to sleep and sleep loss
Q33697922The Unfolded Protein Response Is Not Necessary for the G1/S Transition, but It Is Required for Chromosome Maintenance in Saccharomyces cerevisiae
Q31059949The anaphase-promoting complex or cyclosome supports cell survival in response to endoplasmic reticulum stress.
Q39914245The antiproliferative effect of EPA in HL60 cells is mediated by alterations in calcium homeostasis
Q43145186The apoptotic effect of oral administration of microcystin-RR on mice liver
Q34594217The critical role of GRP78 in physiologic and pathologic stress.
Q37898067The critical role of JNK in the ER-mitochondrial crosstalk during apoptotic cell death
Q37285838The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies
Q40305946The effect of dexamethasone on defective nephrin transport caused by ER stress: a potential mechanism for the therapeutic action of glucocorticoids in the acquired glomerular diseases
Q38159778The effects of being overweight and obese on female reproduction: a review.
Q36954679The endoplasmic reticulum as a potential therapeutic target in nonalcoholic fatty liver disease
Q37410651The endoplasmic reticulum chaperone BiP/GRP78 is important in the structure and function of the human cytomegalovirus assembly compartment
Q35853673The endoplasmic reticulum exit of glutamate transporter is regulated by the inducible mammalian Yip6b/GTRAP3-18 protein
Q35868198The endoplasmic reticulum stress transducer OASIS is involved in the terminal differentiation of goblet cells in the large intestine
Q38201042The essential biology of the endoplasmic reticulum stress response for structural and computational biologists.
Q38979904The evolving role of ubiquitin modification in endoplasmic reticulum-associated degradation
Q28071416The human HSP70 family of chaperones: where do we stand?
Q35950143The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress
Q35612163The loss of glucose-regulated protein 78 (GRP78) during normal aging or from siRNA knockdown augments human alpha-synuclein (α-syn) toxicity to rat nigral neurons
Q38684406The novel role of pyrvinium in cancer therapy.
Q36501163The physiology of membrane transport and endomembrane-based signalling
Q37729054The protective roles of autophagy in ischemic preconditioning
Q83969578The putative Arabidopsis zinc transporter ZTP29 is involved in the response to salt stress
Q38825911The role of ER stress in lipid metabolism and lipotoxicity
Q35791706The role of endoplasmic reticulum stress in autoimmune-mediated beta-cell destruction in type 1 diabetes.
Q36905995The role of fatty acids in the development and progression of nonalcoholic fatty liver disease
Q36333364The role of mRNA and protein sorting in seed storage protein synthesis, transport, and deposition
Q35949048The role of p58IPK in protecting the stressed endoplasmic reticulum
Q35000683The small molecule C-6 is selectively cytotoxic against breast cancer cells and its biological action is characterized by mitochondrial defects and endoplasmic reticulum stress
Q40157250The ubiquitin-selective chaperone CDC-48/p97 links myosin assembly to human myopathy
Q34224697The unfolded protein response (UPR)-activated transcription factor X-box-binding protein 1 (XBP1) induces microRNA-346 expression that targets the human antigen peptide transporter 1 (TAP1) mRNA and governs immune regulatory genes.
Q37444924The unfolded protein response and its relevance to connective tissue diseases.
Q46900500The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress.
Q38784676The unfolded protein response in skeletal development and homeostasis
Q48788070The unfolded protein response in vanishing white matter disease.
Q37164517The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus
Q37804460The unfolded protein response is required to maintain the integrity of the endoplasmic reticulum, prevent oxidative stress and preserve differentiation in β-cells
Q51224682The unfolded protein response mediates fibrogenesis and collagen I secretion through regulating TANGO1 in mice.
Q37825926The unfolded protein response: how protein folding became a restrictive aspect for innate immunity and B lymphocytes
Q35674936Thiamine deficiency induces endoplasmic reticulum stress in neurons.
Q37529613Tocotrienols induce endoplasmic reticulum stress and apoptosis in cervical cancer cells
Q36678786Transcriptional induction of the human asparagine synthetase gene during the unfolded protein response does not require the ATF6 and IRE1/XBP1 arms of the pathway
Q28485361Transcriptional regulation of VEGFA by the endoplasmic reticulum stress transducer OASIS in ARPE-19 cells
Q35102568Transcriptomic responses to high water temperature in two species of Pacific salmon
Q90352222Transfer of the Septin Ring to Cytokinetic Remnants in ER Stress Directs Age-Sensitive Cell-Cycle Re-entry
Q50790859Transgenic mouse model for monitoring endoplasmic reticulum stress in vivo.
Q40094338Translational control of the interferon regulatory factor 2 mRNA by IRES element
Q44157472Treadmill exercise represses neuronal cell death and inflammation during Aβ-induced ER stress by regulating unfolded protein response in aged presenilin 2 mutant mice
Q50710354Trehalose supplementation reduces hepatic endoplasmic reticulum stress and inflammatory signaling in old mice.
Q37845436Tribbles in disease: Signaling pathways important for cellular function and neoplastic transformation
Q90024673Ttc7a regulates hematopoietic stem cell functions while controlling the stress-induced response
Q37215418Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner
Q36544420Tumor cell dormancy induced by p38SAPK and ER-stress signaling: an adaptive advantage for metastatic cells?
Q46656235Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha
Q40892328Tunicamycin promotes apoptosis in leukemia cells through ROS generation and downregulation of survivin expression
Q35763085Two independent mechanisms promote expression of an N-terminal truncated USP18 isoform with higher DeISGylation activity in the nucleus
Q33817822Ube2g2-gp78-mediated HERP polyubiquitylation is involved in ER stress recovery
Q36607342Ubiquitin proteasome system as a pharmacological target in neurodegeneration.
Q34574453Unfolded Protein Response (UPR) is activated during normal lens development
Q57812386Unfolded Protein Response-Dependent Communication and Contact among Endoplasmic Reticulum, Mitochondria, and Plasma Membrane
Q54117911Unfolded protein response is activated in Krabbe disease in a manner dependent on the mutation type.
Q61799897Unfolded protein response is an early, non-critical event during hepatic stellate cell activation
Q41889596Unfolded protein responses with or without unfolded proteins?
Q37308827Unfolding the relationship between secreted molecular chaperones and macrophage activation states
Q34514254Unraveling the contribution of pancreatic beta-cell suicide in autoimmune type 1 diabetes
Q33947812Up-regulation of GRP78 and antiapoptotic signaling in murine peritoneal macrophages exposed to insulin
Q36535498Up-regulation of a cellular protein at the translational level by a retrovirus
Q37606854Up-regulation of endoplasmic reticulum stress induced genes of the unfolded protein response in the liver of periparturient dairy cows
Q42689055Up-regulation of the endoplasmic reticulum molecular chaperone GRP78 during hibernation in thirteen-lined ground squirrels
Q36860811Update on the protective molecular pathways improving pancreatic beta-cell dysfunction
Q48100947Up‐regulation of endoplasmic reticulum stress‐related genes during the early phase of treatment of cultured cortical neurons by the proteasomal inhibitor lactacystin
Q39813335Urban particulate matter causes ER stress and the unfolded protein response in human lung cells
Q41895056VCP inhibitors induce endoplasmic reticulum stress, cause cell cycle arrest, trigger caspase-mediated cell death and synergistically kill ovarian cancer cells in combination with Salubrinal
Q45487957Virus induction of heat shock protein 70 reflects a general response to protein accumulation in the plant cytosol.
Q51825676Voltage dependent anion channel is redistributed during Japanese encephalitis virus infection of insect cells.
Q36322684XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.
Q51219525Xbp1-based engineering of secretory capacity enhances the productivity of Chinese hamster ovary cells.
Q41233374Zbtb38 is a novel target for spinal cord injury.
Q39824387alphaNAC depletion as an initiator of ER stress-induced apoptosis in hypoxia
Q28583302mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway
Q34125608miR-221/222 suppression protects against endoplasmic reticulum stress-induced apoptosis via p27(Kip1)- and MEK/ERK-mediated cell cycle regulation
Q53837718n-3 Polyunsaturated fatty acids protect against pancreatic β-cell damage due to ER stress and prevent diabetes development.
Q42834062p28GANK inhibits endoplasmic reticulum stress-induced cell death via enhancement of the endoplasmic reticulum adaptive capacity
Q35490491tRNA modifications regulate translation during cellular stress
Q35872556Β-adrenergic receptor stimulation induces endoplasmic reticulum stress in adult cardiac myocytes: role in apoptosis
Q58277682α‐Synuclein induces unfolded protein response via distinct signaling pathway independent of er‐membrane kinases