ROS Accumulation by PEITC Selectively Kills Ovarian Cancer Cells via UPR-Mediated Apoptosis

scientific article published on 28 July 2015

ROS Accumulation by PEITC Selectively Kills Ovarian Cancer Cells via UPR-Mediated Apoptosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3389/FONC.2015.00167
P932PMC publication ID4517521
P698PubMed publication ID26284193
P5875ResearchGate publication ID281287654

P50authorMd Hafiz UddinQ85643999
Yoon-Hee HongQ95969308
P2093author name stringYong Sang Song
Hee Seung Kim
Dong Hoon Suh
Boyun Kim
Jiyoung Song
Untek Jo
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Sustained exposure to the DNA demethylating agent, 2'-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagyQ39636724
Sodium selenite induces apoptosis by ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction in human acute promyelocytic leukemia NB4 cellsQ39897732
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Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate.Q40234453
Phenethyl isothiocyanate (PEITC) inhibits growth of ovarian cancer cells by inducing apoptosis: role of caspase and MAPK activation.Q40290293
Celecoxib induces apoptosis in cervical cancer cells independent of cyclooxygenase using NF-kappaB as a possible targetQ40545159
Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathwayQ42817119
Phenethyl isothiocyanate inhibits growth of human chronic myeloid leukemia K562 cells via reactive oxygen species generation and caspasesQ46899018
ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.Q53616050
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Perk is essential for translational regulation and cell survival during the unfolded protein responseQ28140062
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XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein ResponseQ28585314
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Intake of cruciferous vegetables modifies bladder cancer survivalQ33981670
Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cellsQ34074470
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Inhibition of EGFR-AKT axis results in the suppression of ovarian tumors in vitro and in preclinical mouse modelQ34405324
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Update on the management of ovarian cancer.Q34697997
Are isothiocyanates potential anti-cancer drugs?Q34979394
Ovarian cancer management. Practice guidelines for nuclear physiciansQ35831059
Metformin and phenethyl isothiocyanate combined treatment in vitro is cytotoxic to ovarian cancer culturesQ36226632
PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stressQ36311137
Unfolded protein response to autophagy as a promising druggable target for anticancer therapyQ36403652
Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153).Q36561426
Endoplasmic reticulum stress and apoptosis.Q36594912
Endoplasmic reticulum stress sensing in the unfolded protein responseQ36626672
Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword?Q36989869
Unfolded protein response signaling and metabolic diseasesQ37488392
Metabolic approaches to overcoming chemoresistance in ovarian cancer.Q37906707
The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress.Q37977999
Extremely poor postrecurrence oncological outcome for patients with recurrent mucinous ovarian cancerQ38080036
P4510describes a project that usesImageJQ1659584
P921main subjectovarian cancerQ172341
P304page(s)167
P577publication date2015-07-28
P1433published inFrontiers in OncologyQ26839986
P1476titleROS Accumulation by PEITC Selectively Kills Ovarian Cancer Cells via UPR-Mediated Apoptosis
P478volume5

Reverse relations

cites work (P2860)
Q39042225Endoplasmic reticulum-mediated unfolded protein response and mitochondrial apoptosis in cancer
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