scholarly article | Q13442814 |
review article | Q7318358 |
P2093 | author name string | Perry A Christian | |
Steven R Schwarze | |||
Natasha Kyprianou | |||
Eric W Lin | |||
Dustin T Gayheart | |||
P2860 | cites work | ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs | Q24290776 |
Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress | Q24291026 | ||
Caspase-10 is an initiator caspase in death receptor signaling | Q24291922 | ||
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 | ||
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats | Q24298956 | ||
CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells | Q24301679 | ||
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha | Q24322072 | ||
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death | Q24338605 | ||
Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control | Q24522941 | ||
Mendelian inheritance of familial prostate cancer | Q24562051 | ||
Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor | Q24597543 | ||
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response | Q24672592 | ||
Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans. | Q24815740 | ||
Cancer statistics, 2008 | Q27860585 | ||
A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus | Q27930818 | ||
Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway | Q27932953 | ||
The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response | Q27933479 | ||
The unfolded protein response pathway in Saccharomyces cerevisiae. Oligomerization and trans-phosphorylation of Ire1p (Ern1p) are required for kinase activation | Q27936284 | ||
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase | Q27938837 | ||
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition | Q28115131 | ||
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins | Q28117928 | ||
Perk is essential for translational regulation and cell survival during the unfolded protein response | Q28140062 | ||
PERK mediates cell-cycle exit during the mammalian unfolded protein response | Q28141519 | ||
TRAIL receptor-2 signals apoptosis through FADD and caspase-8 | Q28142998 | ||
Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8 | Q28189969 | ||
Translational control is required for the unfolded protein response and in vivo glucose homeostasis | Q28204066 | ||
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). | Q28240752 | ||
Intracellular signaling by the unfolded protein response | Q28250477 | ||
ASK1 is essential for JNK/SAPK activation by TRAF2 | Q28285612 | ||
Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells | Q28294137 | ||
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase | Q28296183 | ||
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress | Q28306995 | ||
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice | Q28359871 | ||
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death | Q28363890 | ||
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1 | Q28507338 | ||
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum | Q28512249 | ||
Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells | Q28513964 | ||
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state | Q28572472 | ||
XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response | Q28585314 | ||
Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair | Q28586758 | ||
bcl-2 deficiency in mice leads to pleiotropic abnormalities: accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine | Q28586868 | ||
Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis | Q28588618 | ||
Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia | Q28591736 | ||
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2 | Q28609079 | ||
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals | Q28646129 | ||
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response | Q29547299 | ||
The mammalian unfolded protein response | Q29547400 | ||
Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls | Q29547730 | ||
Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus | Q29620179 | ||
A trip to the ER: coping with stress | Q29620455 | ||
BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis | Q29620466 | ||
Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis. | Q30554728 | ||
Retrograde protein translocation: ERADication of secretory proteins in health and disease | Q33676998 | ||
Tripartite management of unfolded proteins in the endoplasmic reticulum | Q33941135 | ||
Organelle-specific initiation of cell death pathways | Q34443559 | ||
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression | Q34563098 | ||
Retro-translocation of proteins from the endoplasmic reticulum into the cytosol | Q34627241 | ||
Transcriptional and translational control in the Mammalian unfolded protein response | Q34762452 | ||
Targeting death and decoy receptors of the tumour-necrosis factor superfamily | Q34791120 | ||
ER-associated degradation in protein quality control and cellular regulation | Q34970862 | ||
The CD95(APO-1/Fas) DISC and beyond | Q35091401 | ||
Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses | Q35169632 | ||
Regulation of apoptosis by endoplasmic reticulum pathways. | Q35591699 | ||
Coupling endoplasmic reticulum stress to the cell death program | Q35649891 | ||
Clustering of death receptors in lipid rafts initiates neutrophil spontaneous apoptosis | Q35922798 | ||
ER stress and the unfolded protein response | Q35986601 | ||
The SERCA pump as a therapeutic target: making a "smart bomb" for prostate cancer | Q36015748 | ||
Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153). | Q36561426 | ||
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
Endoplasmic reticulum stress-induced mRNA splicing permits synthesis of transcription factor Hac1p/Ern4p that activates the unfolded protein response | Q38614162 | ||
Stress-induced gene expression requires programmed recovery from translational repression | Q39735685 | ||
Doxazosin induces apoptosis of benign and malignant prostate cells via a death receptor-mediated pathway | Q40333039 | ||
Caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis | Q40405415 | ||
Metastatic carcinoma of the prostate: identifying prognostic groups using recursive partitioning | Q40616118 | ||
Apoptosis in prostate cancer. Molecular basis to study hormone refractory mechanisms | Q40999465 | ||
Regulation of translational initiation during cellular responses to stress | Q41600431 | ||
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. | Q41747264 | ||
Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway | Q42817119 | ||
The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice | Q44489907 | ||
A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca(2+)-ATPases | Q48014886 | ||
Stress-resistance conferred by high level of bcl-2 alpha protein in human B lymphoblastoid cell. | Q53512771 | ||
Ceramide-mediated clustering is required for CD95-DISC formation | Q57369954 | ||
Endoplasmic reticulum-associated protein degradation | Q60526595 | ||
Involvement of the bcl-2 gene in human follicular lymphoma | Q69870224 | ||
Relationship of the structure and biological activity of the natural homologues of tunicamycin | Q70288587 | ||
Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer | Q80352321 | ||
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1 | Q80979487 | ||
PHAPI, CAS, and Hsp70 promote apoptosome formation by preventing Apaf-1 aggregation and enhancing nucleotide exchange on Apaf-1 | Q81160686 | ||
P433 | issue | 15 | |
P921 | main subject | endoplasmic reticulum | Q79927 |
P304 | page(s) | 1615-1623 | |
P577 | publication date | 2008-11-01 | |
P1433 | published in | The Prostate | Q7758608 |
P1476 | title | Intracellular death platform steps-in: targeting prostate tumors via endoplasmic reticulum (ER) apoptosis | |
P478 | volume | 68 |
Q38958946 | Absorption, metabolism, anti-cancer effect and molecular targets of epigallocatechin gallate (EGCG): An updated review |
Q38953684 | Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo |
Q35834796 | Curcumin analog WZ35 induced cell death via ROS-dependent ER stress and G2/M cell cycle arrest in human prostate cancer cells |
Q53510860 | Destruction of DDIT3/CHOP protein by wild-type SPOP but not prostate cancer-associated mutants. |
Q45128372 | Differential effects of thapsigargin analogues on apoptosis of prostate cancer cells: complex regulation by intracellular calcium. |
Q35974731 | Differential targeting of androgen and glucocorticoid receptors induces ER stress and apoptosis in prostate cancer cells: a novel therapeutic modality |
Q47709017 | Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+ depletion and the unfolded protein response. |
Q91713061 | SPOP and cancer: a systematic review |
Q28541919 | Subverting ER-stress towards apoptosis by nelfinavir and curcumin coexposure augments docetaxel efficacy in castration resistant prostate cancer cells |
Q38089963 | Targeting apoptosis by the remodelling of calcium-transporting proteins in cancerogenesis. |
Q34509216 | The Polypeptide Binding Conformation of Calreticulin Facilitates Its Cell-surface Expression under Conditions of Endoplasmic Reticulum Stress |
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