| P2093 | author name string | Kendra K Bence | |
| P2860 | cites work | Alterations in specific protein-tyrosine phosphatases accompany insulin resistance of streptozotocin diabetes | Q72268086 |
| | Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction | Q74191142 |
| | Leptin, obesity, and liver disease | Q77350106 |
| | Insulin signaling in health and disease | Q79347099 |
| | Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein | Q22011200 |
| | Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B | Q24290779 |
| | TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B | Q24291860 |
| | PTP1B regulates leptin signal transduction in vivo | Q24294879 |
| | The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence | Q24301399 |
| | Protein-tyrosine phosphatase 1B is a negative regulator of insulin- and insulin-like growth factor-I-stimulated signaling | Q24311666 |
| | Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice | Q24552910 |
| | Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 |
| | Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice | Q28144106 |
| | Selective deletion of leptin receptor in neurons leads to obesity | Q28361816 |
| | Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress | Q28506667 |
| | Protein-tyrosine phosphatase 1B as new activator for hepatic lipogenesis via sterol regulatory element-binding protein-1 gene expression | Q28570423 |
| | Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 |
| | SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver | Q29547646 |
| | Critical nodes in signalling pathways: insights into insulin action | Q29614735 |
| | Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene | Q29618933 |
| | Cellular mechanisms of insulin resistance | Q29619549 |
| | Protein-tyrosine phosphatase-1B acts as a negative regulator of insulin signal transduction | Q48021656 |
| | 1484insG polymorphism of the PTPN1 gene is associated with insulin resistance in an Iranian population. | Q51469765 |
| | A trip to the ER: coping with stress | Q29620455 |
| | Therapy of NAFLD: insulin sensitizing agents | Q30439790 |
| | Expression of a protein tyrosine phosphatase in normal and v-src-transformed mouse 3T3 fibroblasts | Q30442281 |
| | Analysis of common PTPN1 gene variants in type 2 diabetes, obesity and associated phenotypes in the French population | Q33242462 |
| | PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice | Q33685586 |
| | Inhibition of PTP1B restores IRS1-mediated hepatic insulin signaling in IRS2-deficient mice | Q33688527 |
| | PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice | Q34038299 |
| | Curcumin inhibits hepatic protein-tyrosine phosphatase 1B and prevents hypertriglyceridemia and hepatic steatosis in fructose-fed rats | Q34103434 |
| | Modulation of insulin signaling by protein tyrosine phosphatases. | Q34119787 |
| | Skeletal muscle protein tyrosine phosphatase activity and tyrosine phosphatase 1B protein content are associated with insulin action and resistance | Q34132983 |
| | PTP1B: from the sidelines to the front lines! | Q34209253 |
| | Increased abundance of the receptor-type protein-tyrosine phosphatase LAR accounts for the elevated insulin receptor dephosphorylating activity in adipose tissue of obese human subjects | Q34224154 |
| | Protein tyrosine phosphatases: prospects for therapeutics | Q34318066 |
| | Coordinated action of protein tyrosine phosphatases in insulin signal transduction | Q34539371 |
| | The insulin signalling pathway | Q34590855 |
| | Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis | Q34609585 |
| | Analysis of paradoxical observations on the association between leptin and insulin resistance | Q34770089 |
| | Hepatic insulin resistance, metabolic syndrome and cardiovascular disease | Q34985312 |
| | Protein-tyrosine phosphatase 1B (PTP1B): a novel therapeutic target for type 2 diabetes mellitus, obesity and related states of insulin resistance | Q35023360 |
| | PTP1B inhibitors as potential therapeutics in the treatment of type 2 diabetes and obesity | Q35056063 |
| | Protein tyrosine phosphatase 1B: a novel target for type 2 diabetes and obesity | Q35100837 |
| | Novel concepts in insulin regulation of hepatic gluconeogenesis | Q35213690 |
| | Inhibitors of protein tyrosine phosphatases: next-generation drugs? | Q36131111 |
| | Adipokines: therapeutic targets for metabolic syndrome | Q36198752 |
| | Involvement of the small protein tyrosine phosphatases TC-PTP and PTP1B in signal transduction and diseases: from diabetes, obesity to cell cycle, and cancer | Q36274061 |
| | Insulin resistance: a metabolic pathway to chronic liver disease | Q36297331 |
| | Improved glucose homeostasis in mice with muscle-specific deletion of protein-tyrosine phosphatase 1B. | Q36315662 |
| | Insulin resistance--a common link between type 2 diabetes and cardiovascular disease | Q36458543 |
| | ER stress: can the liver cope? | Q36517489 |
| | The twentieth century struggle to decipher insulin signalling | Q36631664 |
| | Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo | Q36662772 |
| | PTP1B as a drug target: recent developments in PTP1B inhibitor discovery | Q36805716 |
| | Endoplasmic reticulum (ER) stress & diabetes. | Q36819051 |
| | Metabolic syndrome and cardiovascular disease: challenges and opportunities | Q36868655 |
| | Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease | Q36910684 |
| | Targeting protein tyrosine phosphatase to enhance insulin action for the potential treatment of diabetes. | Q36956427 |
| | HF diets increase hypothalamic PTP1B and induce leptin resistance through both leptin-dependent and -independent mechanisms | Q37102835 |
| | Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress | Q37105304 |
| | A variation in 3' UTR of hPTP1B increases specific gene expression and associates with insulin resistance | Q37361629 |
| | Hepatic insulin resistance directly promotes formation of cholesterol gallstones | Q37366384 |
| | Alterations in skeletal muscle protein-tyrosine phosphatase activity and expression in insulin-resistant human obesity and diabetes | Q37370197 |
| | Single nucleotide polymorphisms in protein tyrosine phosphatase 1beta (PTPN1) are associated with essential hypertension and obesity | Q37412376 |
| | Dissecting the role of insulin resistance in the metabolic syndrome | Q37472798 |
| | Attenuation of leptin action and regulation of obesity by protein tyrosine phosphatase 1B. | Q38289920 |
| | Increased expression of the sterol regulatory element-binding protein-1 gene in insulin receptor substrate-2(-/-) mouse liver | Q38297185 |
| | High circulating leptin receptors with normal leptin sensitivity in liver-specific insulin receptor knock-out (LIRKO) mice | Q38301043 |
| | Leptin resistance following over-expression of protein tyrosine phosphatase 1B in liver | Q38316106 |
| | Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus | Q38319698 |
| | Induction of leptin receptor expression in the liver by leptin and food deprivation | Q38332181 |
| | Leptin increases hepatic insulin sensitivity and protein tyrosine phosphatase 1B expression | Q38344544 |
| | Modulation of insulin activities by leptin | Q38351480 |
| | PTP1B antisense-treated mice show regulation of genes involved in lipogenesis in liver and fat. | Q38354027 |
| | Prodrug delivery of novel PTP1B inhibitors to enhance insulin signalling | Q38354830 |
| | Antisense protein tyrosine phosphatase 1B reverses activation of p38 mitogen-activated protein kinase in liver of ob/ob mice | Q38356534 |
| | Leptin but not ciliary neurotrophic factor (CNTF) induces phosphotyrosine phosphatase-1B expression in human neuronal cells (SH-SY5Y): putative explanation of CNTF efficacy in leptin-resistant state | Q39917128 |
| | Glucose enhances protein tyrosine phosphatase 1B gene transcription in hepatocytes | Q40131578 |
| | Hepatic PTP-1B expression regulates the assembly and secretion of apolipoprotein B-containing lipoproteins: evidence from protein tyrosine phosphatase-1B overexpression, knockout, and RNAi studies | Q40488449 |
| | Marked impairment of protein tyrosine phosphatase 1B activity in adipose tissue of obese subjects with and without type 2 diabetes mellitus | Q40936141 |
| | Regulation of gene expression by insulin | Q41169614 |
| | Osmotic loading of neutralizing antibodies demonstrates a role for protein-tyrosine phosphatase 1B in negative regulation of the insulin action pathway | Q41306429 |
| | Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidaemia and atherosclerosis | Q41491513 |
| | The insulin signalling system and the IRS proteins | Q41555426 |
| | Regulation of growth factor-induced signaling by protein-tyrosine-phosphatases | Q41605349 |
| | Differential effects of leptin in regulation of tissue glucose utilization in vivo | Q41648220 |
| | A single nucleotide polymorphism in protein tyrosine phosphatase PTP-1B is associated with protection from diabetes or impaired glucose tolerance in Oji-Cree | Q42166323 |
| | In vivo and in vitro evidence for a hepatic modulation of the leptin signal in rats. | Q42471983 |
| | Hepatic leptin signaling in obesity. | Q42475987 |
| | Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance | Q43764679 |
| | A P387L variant in protein tyrosine phosphatase-1B (PTP-1B) is associated with type 2 diabetes and impaired serine phosphorylation of PTP-1B in vitro | Q43833524 |
| | Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action | Q44805566 |
| | Tyrosine phosphatase 1B and leptin receptor genes and their interaction in type 2 diabetes | Q44930763 |
| | Single nucleotide polymorphisms of protein tyrosine phosphatase 1B gene are associated with obesity in morbidly obese French subjects | Q44965051 |
| | The Pro387Leu variant of protein tyrosine phosphatase-1B is not associated with diabetes mellitus type 2 in a German population. | Q45101724 |
| | Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes | Q45124429 |
| | Liver-specific protein-tyrosine phosphatase 1B (PTP1B) re-expression alters glucose homeostasis of PTP1B-/-mice | Q45256105 |
| | The use of protein tyrosine phosphatase 1B and insulin receptor immunostains to differentiate nonalcoholic from alcoholic steatohepatitis in liver biopsy specimens | Q45295536 |
| | Protein tyrosine phosphatase-1B gene PTPN1: selection of tagging single nucleotide polymorphisms and association with body fat, insulin sensitivity, and the metabolic syndrome in a normal female population | Q46774760 |
| | Improved sensitivity to insulin in obese subjects following weight loss is accompanied by reduced protein-tyrosine phosphatases in adipose tissue | Q47301714 |
| | Neuronal PTP1B regulates body weight, adiposity and leptin action. | Q47329751 |
| P433 | issue | 1 | |
| P921 | main subject | metabolic syndrome | Q657193 |
| P304 | page(s) | 27-33 | |
| P577 | publication date | 2010-05-01 | |
| P1476 | title | Hepatic PTP1B Deficiency: The Promise of a Treatment for Metabolic Syndrome? | |
| P478 | volume | 1 | |