scholarly article | Q13442814 |
P356 | DOI | 10.1126/SCIENCE.274.5290.1185 |
P698 | PubMed publication ID | 8895466 |
P2093 | author name string | Cohen B | |
Novick D | |||
Rubinstein M | |||
P433 | issue | 5290 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | preproinsulin | Q7240673 |
P304 | page(s) | 1185-1188 | |
P577 | publication date | 1996-11-01 | |
P1433 | published in | Science | Q192864 |
P1476 | title | Modulation of insulin activities by leptin | |
P478 | volume | 274 |
Q35683565 | 1. Peroxisome proliferator-activated receptor gamma (PPARgamma) ligands and their therapeutic utility |
Q38340966 | A Leptin Dose-Response Study in Obese (ob/ob) and Lean (+/?) Mice |
Q34751835 | A comparison of novel and commonly-used indices of insulin sensitivity in African American chronic hemodialysis patients |
Q74507329 | Acute and Chronic Effects of Leptin on Glucose Utilization in Lean Mice |
Q51566064 | Acute effect of leptin on hepatic glycogenolysis and gluconeogenesis in perfused rat liver |
Q54121873 | Acute leptin action on insulin blood level and liver insulin receptor in the rat. |
Q59079790 | Acute stimulation of glucose metabolism in mice by leptin treatment |
Q38005991 | Alcoholism and Diabetes Mellitus |
Q37190598 | Amylin and leptin activate overlapping signalling pathways in an additive manner in mouse GT1-7 hypothalamic, C2C12 muscle and AML12 liver cell lines |
Q33286330 | An assessment of serum leptin levels in patients with chronic viral hepatitis: a prospective study |
Q38285318 | Antiepileptic drugs influences on body weight in people with epilepsy. |
Q37145156 | Apolipoprotein A-I gene transfer exerts immunomodulatory effects and reduces vascular inflammation and fibrosis in ob/ob mice. |
Q36582741 | Artemisia iwayomogi Extract Attenuates High-Fat Diet-Induced Obesity by Decreasing the Expression of Genes Associated with Adipogenesis in Mice |
Q47225226 | Associations of leptin, insulin resistance and thyroid function with long-term weight loss in dieting obese men. |
Q58571578 | Bergamot Polyphenols Boost Therapeutic Effects of the Diet on Non-Alcoholic Steatohepatitis (NASH) Induced by "Junk Food": Evidence for Anti-Inflammatory Activity |
Q28373740 | Bezafibrate reduces blood glucose in type 2 diabetes mellitus |
Q38312057 | Binding of a pure 125I-monoiodoleptin analog to mouse tissues: a developmental study |
Q36180254 | Biomarker Profiles in Women with PCOS and PCOS Offspring; A Pilot Study. |
Q37120226 | Changes in insulin sensitivity during leptin replacement therapy in leptin-deficient patients |
Q73510740 | Changes in plasma leptin and insulin action with resistive training in postmenopausal women |
Q35825637 | Characterization of a new animal model of metabolic syndrome: the DahlS.Z-Leprfa/Leprfa rat |
Q44355158 | Chemical sympathectomy alters regulation of body weight during prolonged ICV leptin infusion |
Q38324413 | Chronic leptin administration increases insulin-stimulated skeletal muscle glucose uptake and transport |
Q38331495 | Circulating leptin did not associate with the development of the hyperglycemia accompanied by insulin insensitivity in spontaneous noninsulin dependent diabetes mellitus model Otsuka-Long-Evans-Tokushima-Fatty rats |
Q39703615 | Clinicopathological features of non‐alcoholic fatty liver disease |
Q40457400 | Cross down-regulation of leptin and insulin receptor expression and signalling in a human neuronal cell line. |
Q46370969 | Cross-talk between the insulin and leptin signaling systems in rat hypothalamus. |
Q33808147 | Current concepts concerning the role of leptin in reproductive function |
Q37599777 | Cytokeratin-18 fragments and biomarkers of the metabolic syndrome in nonalcoholic steatohepatitis |
Q47908901 | Cytokine-induced Patterns of Gene Expression in Skeletal Muscle Tissue |
Q36617125 | Cytokines in type 2 diabetes. |
Q35049249 | Deep sequencing of small RNA repertoires in mice reveals metabolic disorders-associated hepatic miRNAs |
Q43152301 | Diabetic and nondiabetic patients express similar adipose tissue adiponectin and leptin levels |
Q37421239 | Dietary fish oil exerts hypolipidemic effects in lean and insulin sensitizing effects in obese LDLR-/- mice |
Q37362218 | Differential metabolic effects of pravastatin and simvastatin in hypercholesterolemic patients. |
Q38332960 | Differential regulation of fatty acid amide hydrolase promoter in human immune cells and neuronal cells by leptin and progesterone |
Q34343429 | Disease model: hyperinsulinemia and insulin resistance. Part B--polygenic and other animal models. |
Q34355179 | Disruption of Hepatic Leptin Signaling Protects Mice From Age- and Diet-Related Glucose Intolerance |
Q35117843 | Distribution, function, and properties of leptin receptors in the brain |
Q28610099 | Divergent Signaling Capacities of the Long and Short Isoforms of the Leptin Receptor |
Q43628855 | Dual action of eicosapentaenoic acid in hepatoma cells: up-regulation of metabolic action of insulin and inhibition of cell proliferation. |
Q37173164 | Dysregulation of glucocorticoid metabolism in murine obesity: comparable effects of leptin resistance and deficiency |
Q38355387 | Early intracellular events induced by in vivo leptin treatment in mouse skeletal muscle. |
Q44427153 | Effect of Garcinia cambogia extract on serum leptin and insulin in mice |
Q36311666 | Effect of pioglitazone on the fructose-induced abdominal adipose tissue dysfunction |
Q44473934 | Effect of thiazolidinediones on glucose and fatty acid metabolism in patients with type 2 diabetes |
Q34743351 | Effects of free fatty acids on insulin secretion in obesity |
Q53882426 | Effects of leptin and dexamethasone on long and short leptin receptor mRNA. |
Q52120730 | Embryonic expression of the leptin receptor gene in mesoderm-derived tissues |
Q33936953 | Etiology of the metabolic syndrome: potential role of insulin resistance, leptin resistance, and other players |
Q38341447 | Expression of Functional Leptin Receptors in the Human Ovary1 |
Q38321639 | Expression of leptin and its long-form receptor in the marginal cutaneous tissues of diabetic foot ulcers |
Q38328264 | Expression of leptin receptor in lung: leptin as a growth factor |
Q86034418 | FFAs and adipokine-mediated regulation of hsa-miR-143 expression in human adipocytes |
Q34032047 | Fasting plasma leptin level is a surrogate measure of insulin sensitivity |
Q47279409 | Four-week ethanol intake decreases food intake and body weight but does not affect plasma leptin, corticosterone, and insulin levels in pubertal rats |
Q53808638 | Free androgen index and Irisin in polycystic ovary syndrome |
Q46150332 | Fructose-rich diet-induced abdominal adipose tissue endocrine dysfunction in normal male rats |
Q58329801 | Gender difference in the leptin response to feeding in peroxisome-proliferator-activated receptor-alpha knockout mice |
Q73083602 | Glycemic status and soluble tumor necrosis factor receptor levels in relation to plasma leptin concentrations among normal weight and overweight US men |
Q35644631 | Helicobacter pylori Infection Increases Insulin Resistance and Metabolic Syndrome in Residents Younger than 50 Years Old: A Community-Based Study |
Q30361927 | Helicobacter pylori infection and diabetes: is it a myth or fact? |
Q51437139 | Helicobacter pylori infection as a risk factor for insulin resistance. |
Q84008571 | Hepatic PTP1B Deficiency: The Promise of a Treatment for Metabolic Syndrome? |
Q38329197 | Hepatic leptin signalling and subdiaphragmatic vagal efferents are not required for leptin-induced increases of plasma IGF binding protein-2 (IGFBP-2) in ob/ob mice |
Q24630367 | High stearoyl-CoA desaturase 1 expression is associated with shorter survival in breast cancer patients |
Q33602280 | Hormonal and metabolic factors associated with variations in insulin sensitivity in human pregnancy. |
Q37079398 | Hormonal regulation of hippocampal dendritic morphology and synaptic plasticity |
Q59088199 | IRS-2 pathways integrate female reproduction and energy homeostasis |
Q40838534 | Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor |
Q37929753 | Impact of HCV genetic differences on pathobiology of disease. |
Q38832643 | Impact of statin therapy on plasma leptin concentrations: a systematic review and meta-analysis of randomized placebo-controlled trials |
Q42485429 | Impact of transient correction of increased adrenocortical activity in hypothalamo-damaged, hyperadipose female rats |
Q43669417 | Impaired biliary lipid secretion in obese Zucker rats: leptin promotes hepatic cholesterol clearance |
Q77769324 | Impaired glucose metabolism in the heart of obese Zucker rats after treatment with phorbol ester |
Q37244236 | Implications of gene-behavior interactions: prevention and intervention for obesity |
Q42981587 | In overweight patients with chronic hepatitis C, circulating insulin is associated with hepatic fibrosis: implications for therapy. |
Q38332181 | Induction of leptin receptor expression in the liver by leptin and food deprivation |
Q34006674 | Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice |
Q61451402 | Influence of leptin and insulin on lipid transfer proteins in human hepatoma cell line, HepG2 |
Q35074531 | Insulin and leptin revisited: adiposity signals with overlapping physiological and intracellular signaling capabilities |
Q41014152 | Insulin occludes leptin activation of ATP-sensitive K+ channels in rat CRI-G1 insulin secreting cells. |
Q40029303 | Insulin receptor substrate 4 couples the leptin receptor to multiple signaling pathways |
Q43780595 | Insulin resistance and glucose-induced thermogenesis in critical illness |
Q36160709 | Insulin resistance and steatosis in hepatitis C virus infection. |
Q43963236 | Insulin resistance in moderate chronic heart failure is related to hyperleptinaemia, but not to norepinephrine or TNF-alpha |
Q34096908 | Insulin resistance with aging: effects of diet and exercise |
Q44389682 | Interaction between leptin and insulin signaling pathways differentially affects JAK-STAT and PI 3-kinase-mediated signaling in rat liver. |
Q73799873 | Interrelationship between insulin, leptin and growth hormone in growth hormone-treated children |
Q54120598 | Intracerebroventricular administration of leptin markedly enhances insulin sensitivity and systemic glucose utilization in conscious rats |
Q46011223 | Investigation of the acute effect of leptin on the inhibition of glycogen catabolism by insulin in rat liver perfused in situ. |
Q38330326 | Is there a role for leptin in human reproduction? |
Q38963426 | Ketoacid Supplementation Partially Improves Metabolic Parameters in Patients on Peritoneal Dialysis |
Q57244364 | Leptin |
Q38349675 | Leptin Stimulates Insulin Secretion and Synthesis in HIT-T 15 Cells |
Q73923007 | Leptin activates PI-3 kinase in C2C12 myotubes via janus kinase-2 (JAK-2) and insulin receptor substrate-2 (IRS-2) dependent pathways |
Q38358196 | Leptin activates the anandamide hydrolase promoter in human T lymphocytes through STAT3. |
Q37198354 | Leptin and cardiovascular disease: response to therapeutic interventions |
Q33680494 | Leptin and its potential role in human obesity |
Q38330261 | Leptin and its receptors: regulators of whole-body energy homeostasis |
Q35025276 | Leptin and melanocortin signaling in the hypothalamus |
Q35290021 | Leptin and metabolic hormones in infants of diabetic mothers |
Q58647796 | Leptin and other components of the Metabolic Syndrome in Mauritius—a factor analysis |
Q30662008 | Leptin and the adrenal gland |
Q34454916 | Leptin and the regulation of body weight |
Q34548531 | Leptin and the regulation of food intake, energy homeostasis and immunity with special focus on periparturient ruminants |
Q37371856 | Leptin constrains acetylcholine-induced insulin secretion from pancreatic islets of ob/ob mice |
Q44148453 | Leptin determination in colostrum and early human milk from mothers of preterm and term infants |
Q42464395 | Leptin does not affect adipocyte glucose metabolism: studies in fresh and cultured adipocytes |
Q43001164 | Leptin has no role in determining severity of steatosis and fibrosis in patients with chronic hepatitis C. |
Q38171375 | Leptin in chronic kidney disease: a link between hematopoiesis, bone metabolism, and nutrition |
Q31045022 | Leptin in hepatic fibrosis: evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice |
Q35119544 | Leptin in the CNS: much more than a satiety signal. |
Q36587716 | Leptin in the field of hepatic fibrosis: a pivotal or an incidental player? |
Q77534765 | Leptin increases glucose transport and utilization in skeletal muscle in vitro |
Q42832711 | Leptin induces angiopoietin-2 expression in adipose tissues |
Q53466917 | Leptin inhibits amyloid β-protein fibrillogenesis by decreasing GM1 gangliosides on the neuronal cell surface through PI3K/Akt/mTOR pathway |
Q28116312 | Leptin inhibits glucose intestinal absorption via PKC, p38MAPK, PI3K and MEK/ERK |
Q38344302 | Leptin inhibits glycogen synthesis in the isolated soleus muscle of obese (ob/ob) mice |
Q37384674 | Leptin inhibits insulin secretion by activation of phosphodiesterase 3B |
Q38307707 | Leptin is a potent stimulator of bone growth in ob/ob mice |
Q77659059 | Leptin levels and gene expression during the perinatal phase in the rat |
Q42447612 | Leptin levels and insulin sensitivity in obese and non-obese patients with polycystic ovary syndrome |
Q38336224 | Leptin produces anorexia and weight loss without inducing an acute phase response or protein wasting |
Q35694487 | Leptin promotes fibroproliferative acute respiratory distress syndrome by inhibiting peroxisome proliferator-activated receptor-γ |
Q38340183 | Leptin rapidly suppresses insulin release from insulinoma cells, rat and human islets and, in vivo, in mice |
Q38335468 | Leptin receptor isoforms expressed in human adipose tissue |
Q38343837 | Leptin receptors in the adrenal medulla of the rat |
Q38329524 | Leptin repletion restores depressed {beta}-adrenergic contractility in ob/ob mice independently of cardiac hypertrophy |
Q44312396 | Leptin response to glucocorticoid occurs at physiological doses and is abolished by fasting |
Q35360626 | Leptin secretion and leptin receptor in the human stomach |
Q37376534 | Leptin selectively decreases visceral adiposity and enhances insulin action. |
Q36576492 | Leptin signaling and Alzheimer's disease |
Q34646543 | Leptin signalling |
Q40908774 | Leptin stimulates glucose uptake in C2C12 muscle cells by activation of ERK2. |
Q42443400 | Leptin suppresses basal insulin secretion from rat pancreatic islets |
Q34130674 | Leptin suppression of insulin secretion by the activation of ATP-sensitive K+ channels in pancreatic beta-cells |
Q35796934 | Leptin therapy reverses hyperglycemia in mice with streptozotocin-induced diabetes, independent of hepatic leptin signaling. |
Q36700877 | Leptin therapy, insulin sensitivity, and glucose homeostasis. |
Q38322266 | Leptin treatment increases suppressors of cytokine signaling in central and peripheral tissues |
Q41752514 | Leptin, Leptin Receptors, and the Control of Body Weight |
Q34635545 | Leptin, gut, and food intake |
Q77350106 | Leptin, obesity, and liver disease |
Q77329834 | Leptin--new knowledge on the pathogenesis of obesity |
Q89664105 | Leptin-mediated differential regulation of microsomal triglyceride transfer protein in the intestine and liver affects plasma lipids |
Q42448026 | Leptin: A Potent Inhibitor of Insulin Secretion |
Q35622301 | Leptin: a multifaceted hormone in the central nervous system. |
Q33969414 | Leptin: a multifunctional hormone |
Q34548538 | Leptin: a possible metabolic signal affecting reproduction |
Q56169405 | Leptin: a review of its peripheral actions and interactions |
Q33905678 | Leptin: an essential regulator of lipid metabolism |
Q33590455 | Leptin: in search of role(s) in human physiology and pathophysiology |
Q35600185 | Leptin: obesity, diabetes and other peripheral effects--a review |
Q33873705 | Local leptin production in osteoarthritis subchondral osteoblasts may be responsible for their abnormal phenotypic expression |
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Q43908125 | Middle-aged C57BL/6 mice have impaired responses to leptin that are not improved by calorie restriction |
Q77211609 | Modulation of insulin secretion by leptin |
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Q36961972 | Murine Models of Nonalcoholic Fatty Liver Disease and Steatohepatitis. |
Q36825535 | Neuropoietin attenuates adipogenesis and induces insulin resistance in adipocytes |
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Q40707333 | Nonalcoholic fatty liver disease following liver transplantation |
Q35160996 | Novel actions of leptin in the hippocampus |
Q38338847 | Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin |
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Q37383968 | Obesity and diabetes in TNF-alpha receptor- deficient mice |
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Q42489242 | Ovarian action of leptin: effects on insulin-like growth factor-I-stimulated function of granulosa and thecal cells |
Q27865234 | Overexpression of GPR40 in pancreatic beta-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice |
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Q38334495 | Pivotal role of leptin in insulin effects |
Q43687657 | Plasma insulin, leptin, and soluble TNF receptors levels in relation to obesity-related atherogenic and thrombogenic cardiovascular disease risk factors among men. |
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