| P2093 | author name string | Proietto J | |
| | Dunlop M | |
| | Andrikopoulos S | |
| | Zraika S | |
| P2860 | cites work | Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension | Q22011018 |
| | Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia | Q24324798 |
| | Obesity and insulin resistance | Q24607078 |
| | The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus | Q28190307 |
| | Electrophysiology of the pancreatic beta-cell | Q28240546 |
| | Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids | Q28361455 |
| | Banting lecture 1988. Role of insulin resistance in human disease | Q29547283 |
| | The hormone resistin links obesity to diabetes | Q29616100 |
| | Fatty acids, lipotoxicity and insulin secretion | Q33537945 |
| | Metabolic complications of obesity | Q34143830 |
| | Skeletal muscle utilization of free fatty acids in women with visceral obesity | Q34211446 |
| | Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation. | Q43687834 |
| | Glucose-dependent arginine stimulation test for characterization of islet function: studies on reproducibility and priming effect of arginine | Q47755819 |
| | The effects of saturated fatty acids on endothelial cells | Q50796729 |
| | Exogenous arachidonic acid promotes insulin release from intact or permeabilized rat islets by dual mechanisms. Putative activation of Ca2+ mobilization and protein kinase C. | Q50893634 |
| | Lowering fatty acids potentiates acute insulin response in first degree relatives of people with type II diabetes. | Q51567209 |
| | Short term effects of leptin on hepatic gluconeogenesis and in vivo insulin action. | Q51573255 |
| | Abdominal fat and insulin resistance in normal and overweight women: Direct measurements reveal a strong relationship in subjects at both low and high risk of NIDDM. | Q51581803 |
| | Effect of new oral antidiabetic agent CS-045 on glucose tolerance and insulin secretion in patients with NIDDM. | Q51608769 |
| | Effect of acute elevation of plasma glycerol, triglyceride and FFA levels on glucose utilization and plasma insulin. | Q51688560 |
| | Stimulation of islet protein kinase C translocation by palmitate requires metabolism of the fatty acid | Q52553406 |
| | Activation of the ATP-sensitive K+ channel by long chain acyl-CoA. A role in modulation of pancreatic beta-cell glucose sensitivity | Q53987542 |
| | Insulin responses to glucose: evidence for a two pool system in man | Q34283761 |
| | Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone | Q34324049 |
| | After insulin binds | Q34398025 |
| | Leptin: the tale of an obesity gene | Q34402454 |
| | Stimulation of insulin secretion by long-chain free fatty acids. A direct pancreatic effect | Q34509593 |
| | Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus | Q34617065 |
| | Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes | Q35923385 |
| | Role of peroxisome proliferator-activated receptor α in disease of pancreatic β cells | Q36226235 |
| | Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat. | Q37356303 |
| | Role of nitric oxide in obesity-induced beta cell disease | Q37369915 |
| | The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation | Q37370093 |
| | Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation | Q37378805 |
| | A fatty acid- dependent step is critically important for both glucose- and non-glucose-stimulated insulin secretion | Q37382445 |
| | Banting lecture 1990. Beta-cells in type II diabetes mellitus | Q37633379 |
| | Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease | Q37742798 |
| | Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes. | Q38299277 |
| | Characterization of new oral antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats | Q38346193 |
| | Modulation of insulin activities by leptin | Q38351480 |
| | Human insulin secretion: as integrated approach | Q39990805 |
| | Significance of ionic fluxes and changes in membrane potential for stimulus-secretion coupling in pancreatic B-cells | Q40189725 |
| | Insulin secretion in diabetes mellitus | Q40302183 |
| | Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle | Q40334538 |
| | Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications. | Q40452210 |
| | Regulation of pancreatic insulin and glucagon secretion | Q40493648 |
| | Mechanisms modifying glucose oxidation in diabetes mellitus | Q40569595 |
| | Uncoupling protein 2: a possible link between fatty acid excess and impaired glucose-induced insulin secretion? | Q40814727 |
| | Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells | Q40838108 |
| | Long-chain acyl CoA regulation of protein kinase C and fatty acid potentiation of glucose-stimulated insulin secretion in clonal beta-cells | Q40877140 |
| | Inhibition of insulin gene expression by long-term exposure of pancreatic beta cells to palmitate is dependent on the presence of a stimulatory glucose concentration | Q40885653 |
| | Two novel immortal pancreatic beta-cell lines expressing and secreting human islet amyloid polypeptide do not spontaneously develop islet amyloid. | Q40924518 |
| | Palmitate and oleate induce the immediate-early response genes c-fos and nur-77 in the pancreatic beta-cell line INS-1. | Q40924790 |
| | Are the beta-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM? | Q40965216 |
| | Chronic effect of fatty acids on insulin release is not through the alteration of glucose metabolism in a pancreatic beta-cell line (βHC9) | Q41090521 |
| | Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1. | Q41126359 |
| | Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis | Q41128299 |
| | Adipocyte hormone-sensitive lipase: a major regulator of lipid metabolism | Q41131878 |
| | Induction by glucose of genes coding for glycolytic enzymes in a pancreatic beta-cell line (INS-1). | Q41132319 |
| | Thiazolidinediones in the treatment of insulin resistance and type II diabetes | Q41217443 |
| | Morphological and functional characterization of beta TC-6 cells--an insulin-secreting cell line derived from transgenic mice | Q41367385 |
| | Murine insulinoma cell line with normal glucose-regulated insulin secretion | Q41549148 |
| | Fat-induced changes in mouse pancreatic islet insulin secretion, insulin biosynthesis and glucose metabolism | Q41870796 |
| | Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans | Q42461702 |
| | Caloric restriction in obese pre-diabetic rats prevents beta-cell depletion, loss of beta-cell GLUT 2 and glucose incompetence | Q42484710 |
| | Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes | Q42489695 |
| | Mechanisms of the stimulation of insulin release by saturated fatty acids. A study of palmitate effects in mouse beta-cells | Q42500299 |
| | Effect of experimental elevation of free fatty acids on insulin secretion and insulin sensitivity in healthy carriers of the Pro12Ala polymorphism of the peroxisome proliferator--activated receptor-gamma2 gene | Q42503780 |
| | A role for hormone-sensitive lipase in glucose-stimulated insulin secretion: a study in hormone-sensitive lipase-deficient mice. | Q42509218 |
| | Retinoids activate proton transport by the uncoupling proteins UCP1 and UCP2. | Q42685139 |
| | Regulation of insulin secretion studied with pieces of rabbit pancreas incubated in vitro | Q42965104 |
| | Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function | Q43516835 |
| | Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets. | Q43616980 |
| | Activation of acetyl-CoA carboxylase by a glutamate- and magnesium-sensitive protein phosphatase in the islet beta-cell | Q43651813 |
| P433 | issue | 2 | |
| P921 | main subject | obesity | Q12174 |
| | preproinsulin | Q7240673 |
| | fatty acid | Q61476 |
| P304 | page(s) | 103-112 | |
| P577 | publication date | 2002-05-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Obesity Reviews | Q15716706 |
| P1476 | title | Effects of free fatty acids on insulin secretion in obesity | |
| P478 | volume | 3 | |