| scholarly article | Q13442814 |
| P356 | DOI | 10.1124/MOL.116.103861 |
| P698 | PubMed publication ID | 27436126 |
| P50 | author | Marcia Hiriart | Q37828725 |
| P2093 | author name string | Myrian Velasco | |
| Carlos Larqué | |||
| Carlos Manlio Díaz-García | |||
| P2860 | cites work | Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor | Q24304448 |
| Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes | Q24338339 | ||
| Quercetin induces insulin secretion by direct activation of L-type calcium channels in pancreatic beta cells | Q24606210 | ||
| The hitchhiker's guide to the voltage-gated sodium channel galaxy | Q26771787 | ||
| The Nucleotide-Binding Sites of SUR1: A Mechanistic Model | Q26774807 | ||
| The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic Potential | Q26781422 | ||
| The Diagnosis and Management of Hyperinsulinaemic Hypoglycaemia | Q26796476 | ||
| GLP‐1 receptor activated insulin secretion from pancreatic β‐cells: mechanism and glucose dependence | Q26858990 | ||
| The central role of calcium in the effects of cytokines on beta-cell function: implications for type 1 and type 2 diabetes | Q26860579 | ||
| Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter | Q27684709 | ||
| Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet beta-cells: mediation by PLC and L-type Ca2+ channel and link to insulin release | Q27863811 | ||
| Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patients | Q27863911 | ||
| Characterization of voltage-dependent sodium and calcium channels in mouse pancreatic A- and B-cells | Q27863914 | ||
| The role of voltage-gated calcium channels in pancreatic beta-cell physiology and pathophysiology | Q27863928 | ||
| RNA sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate | Q39038213 | ||
| Extracellular calcium influx activates adenylate cyclase 1 and potentiates insulin secretion in MIN6 cells | Q39217687 | ||
| Akt Signals Upstream of L-Type Calcium Channels to Optimize Insulin Secretion | Q39500428 | ||
| Neonatal diabetes caused by a homozygous KCNJ11 mutation demonstrates that tiny changes in ATP sensitivity markedly affect diabetes risk | Q39818672 | ||
| The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts | Q39863117 | ||
| Modulation of microRNA-375 expression alters voltage-gated Na(+) channel properties and exocytosis in insulin-secreting cells | Q40031615 | ||
| Saturated and cis/trans unsaturated acyl CoA esters differentially regulate wild-type and polymorphic beta-cell ATP-sensitive K+ channels | Q40404146 | ||
| Role of high-voltage-activated calcium channels in glucose-regulated beta-cell calcium homeostasis and insulin release | Q40409873 | ||
| Kir6.2 polymorphisms sensitize beta-cell ATP-sensitive potassium channels to activation by acyl CoAs: a possible cellular mechanism for increased susceptibility to type 2 diabetes? | Q40630833 | ||
| The functional significance of sodium channels in pancreatic beta-cell membranes | Q40782509 | ||
| Molecular structure of the glibenclamide binding site of the beta-cell K(ATP) channel | Q40797523 | ||
| Tyrosine kinases play a permissive role in glucose-induced insulin secretion from adult rat islets. | Q40977091 | ||
| Anionic phospholipids activate ATP-sensitive potassium channels | Q41126627 | ||
| Abnormally expressed low-voltage-activated calcium channels in beta-cells from NOD mice and a related clonal cell line | Q41149735 | ||
| Reinterpreting the Action of ATP Analogs on KATP Channels | Q41469020 | ||
| A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels | Q41644878 | ||
| Syntaxin-1A Interacts with Distinct Domains within Nucleotide-binding Folds of Sulfonylurea Receptor 1 to Inhibit β-Cell ATP-sensitive Potassium Channels | Q41874008 | ||
| The Ionic, Electrical, and Secretory Effects of Endogenous Cyclic Adenosine Monophosphate in Mouse Pancreatic B Cells: Studies with Forskolin* | Q42444921 | ||
| Participation of Na(+) channels in the potentiation by Tityus serrulatus alpha-toxin TsTx-V of glucose-induced electrical activity and insulin secretion in rodent islet beta-cells | Q42444974 | ||
| Inhibition of protein kinase C (PKC) response of voltage-gated calcium (Cav)2.2 channels expressed in Xenopus oocytes by Cavβ subunits | Q42465574 | ||
| Decreased expression of t-SNARE, syntaxin 1, and SNAP-25 in pancreatic beta-cells is involved in impaired insulin secretion from diabetic GK rat islets: restoration of decreased t-SNARE proteins improves impaired insulin secretion | Q42480566 | ||
| Long-term in vitro treatment of INS-1 rat pancreatic β-cells by unsaturated free fatty acids protects cells against gluco- and lipotoxicities via activation of GPR40 receptors | Q42502106 | ||
| Nerve growth factor increases insulin secretion and barium current in pancreatic beta-cells | Q42507809 | ||
| Muscarinic modulation of insulin secretion by single pancreatic beta-cells | Q42508071 | ||
| Effect of the insulin mimetic L-783,281 on intracellular Ca2+ and insulin secretion from pancreatic beta-cells | Q42516512 | ||
| Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression | Q43052828 | ||
| The human L-type calcium channel Cav1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes | Q43586741 | ||
| Signaling in channel/enzyme multimers: ATPase transitions in SUR module gate ATP-sensitive K+ conductance | Q43705208 | ||
| Nerve growth factor increases sodium channel expression in pancreatic beta cells: implications for insulin secretion | Q44012016 | ||
| Nerve growth factor increases L-type calcium current in pancreatic beta cells in culture. | Q44083257 | ||
| Phosphatidylinositol 4,5-bisphosphate (PIP2) modulation of ATP and pH sensitivity in Kir channels. A tale of an active and a silent PIP2 site in the N terminus | Q44270128 | ||
| Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes | Q44286433 | ||
| The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes | Q44286437 | ||
| Sodium channels contribute to action potential generation in canine and human pancreatic islet B cells | Q44530839 | ||
| Long-chain CoA esters activate human pancreatic beta-cell KATP channels: potential role in Type 2 diabetes | Q44739809 | ||
| Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective po | Q44953905 | ||
| Autocrine regulation of single pancreatic beta-cell survival | Q44995529 | ||
| Ion channels underlying stimulus-exocytosis coupling and its cell-to-cell heterogeneity in beta-cells of transplantable porcine islets of Langerhans | Q46109709 | ||
| Nerve growth factor promotes development of glucose-induced insulin secretion in rat neonate pancreatic beta cells by modulating calcium channels | Q46438595 | ||
| Requirements of calcium fluxes and ERK kinase activation for glucose- and interleukin-1beta-induced beta-cell apoptosis | Q46580612 | ||
| Functional effects of KCNJ11 mutations causing neonatal diabetes: enhanced activation by MgATP. | Q46640868 | ||
| ATP Regulates Sodium Channel Kinetics in Pancreatic Islet Beta Cells | Q46686727 | ||
| The combined use of insulin and sulfonylurea therapy in patients with non-insulin dependent diabetes mellitus | Q46875036 | ||
| Pancreatic β-cell Na+ channels control global Ca2+ signaling and oxidative metabolism by inducing Na+ and Ca2+ responses that are propagated into mitochondria. | Q47885969 | ||
| Channelopathies, painful neuropathy, and diabetes: which way does the causal arrow point? | Q48257623 | ||
| Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif | Q48792360 | ||
| Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K(ATP) channel | Q48917262 | ||
| The interaction of nucleotides with the tolbutamide block of cloned ATP-sensitive K+ channel currents expressed in Xenopus oocytes: a reinterpretation | Q48950855 | ||
| Intracellular cAMP potentiates voltage-dependent activation of L -type Ca 2+ channels in rat islet β-cells | Q51527031 | ||
| Glucose induces cytoplasmic Na+ oscillations in pancreatic beta-cells | Q51562051 | ||
| Voltage-dependent Na+ and Ca2+ currents in human pancreatic islet beta-cells: evidence for roles in the generation of action potentials and insulin secretion | Q51585431 | ||
| Relationships between plasma-free fatty acid concentration, endogenous glucose production, and fasting hyperglycemia in normal and non-insulin-dependent diabetic individuals | Q51629318 | ||
| Defining a binding pocket for sulfonylureas in ATP-sensitive potassium channels | Q51802142 | ||
| Calcium and delayed potassium currents in mouse pancreatic beta-cells under voltage-clamp conditions | Q51810485 | ||
| Na+ currents in cultured mouse pancreatic B-cells | Q52568762 | ||
| Importance of the Kir6.2 N-terminus for the interaction of glibenclamide and repaglinide with the pancreatic K(ATP) channel | Q52618285 | ||
| Activation of the ATP-sensitive K+ channel by long chain acyl-CoA. A role in modulation of pancreatic beta-cell glucose sensitivity | Q53987542 | ||
| Voltage-gated ion channels in human pancreatic beta-cells: electrophysiological characterization and role in insulin secretion | Q54538745 | ||
| Modulation of L-type Ca2+Channels by Gβγ and Calmodulin via Interactions with N and C Termini of α1C | Q58539221 | ||
| Sodium channel β subunits: emerging targets in channelopathies | Q28082122 | ||
| Structure and regulation of voltage-gated Ca2+ channels | Q28141138 | ||
| Molecular biology of adenosine triphosphate-sensitive potassium channels | Q28141603 | ||
| From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels | Q28143653 | ||
| ATP4- mediates closure of pancreatic beta-cell ATP-sensitive potassium channels by interaction with 1 of 4 identical sites | Q28145223 | ||
| Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor | Q28237709 | ||
| Voltage-Gated Calcium Channels | Q28242997 | ||
| Mechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoA | Q28284068 | ||
| International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels | Q28289125 | ||
| Chelation of divalent cations by ATP, studied by titration calorimetry | Q28321274 | ||
| Syntaxin-1A binds the nucleotide-binding folds of sulphonylurea receptor 1 to regulate the KATP channel | Q28578857 | ||
| High-content screening identifies a role for Na(+) channels in insulin production | Q28601968 | ||
| AMPK regulates K(ATP) channel trafficking via PTEN inhibition in leptin-treated pancreatic β-cells | Q29568323 | ||
| Leptin and the regulation of body weight in mammals | Q29615976 | ||
| Stress-induced dissociations between intracellular calcium signaling and insulin secretion in pancreatic islets | Q30300205 | ||
| Structural basis for the mechanism of ABC transporters. | Q30380838 | ||
| Evidence that low-grade systemic inflammation can induce islet dysfunction as measured by impaired calcium handling | Q30430981 | ||
| Neprilysin deficiency protects against fat-induced insulin secretory dysfunction by maintaining calcium influx | Q30539196 | ||
| ATP modulation of ATP-sensitive potassium channel ATP sensitivity varies with the type of SUR subunit | Q31685657 | ||
| CaM kinase II: a protein kinase with extraordinary talents germane to insulin exocytosis | Q33548178 | ||
| Inhibition of pancreatic β-cell Ca2+/calmodulin-dependent protein kinase II reduces glucose-stimulated calcium influx and insulin secretion, impairing glucose tolerance | Q33556105 | ||
| Multiparameter screening reveals a role for Na+ channels in cytokine-induced β-cell death | Q33632201 | ||
| Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4 | Q33728169 | ||
| Ions, genes and insulin release: from basic science to clinical disease. Based on the 1998 R. D. Lawrence Lecture | Q33880824 | ||
| Molecular mechanisms of neurotoxin action on voltage-gated sodium channels. | Q33925844 | ||
| GLUT2 (SLC2A2) is not the principal glucose transporter in human pancreatic beta cells: implications for understanding genetic association signals at this locus | Q34216678 | ||
| Syntaxin-3 and syntaxin-1A inhibit L-type calcium channel activity, insulin biosynthesis and exocytosis in beta-cell lines | Q34267170 | ||
| Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion | Q34308492 | ||
| Structural diversity of ABC transporters. | Q34410603 | ||
| Ionic mechanisms in pancreatic β cell signaling | Q34430333 | ||
| N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2 | Q34618893 | ||
| Syntaxin 1A regulates surface expression of beta-cell ATP-sensitive potassium channels. | Q34718049 | ||
| Effects of free fatty acids on insulin secretion in obesity | Q34743351 | ||
| Physiology and pathophysiology of K(ATP) channels in the pancreas and cardiovascular system: a review | Q35080216 | ||
| Electrophysiology of pancreatic β-cells in intact mouse islets of Langerhans | Q37901596 | ||
| Regulation of calcium in pancreatic α- and β-cells in health and disease | Q37969351 | ||
| Update on incretin hormones | Q38006504 | ||
| K(ATP) channels and islet hormone secretion: new insights and controversies | Q38138370 | ||
| Leptin-stimulated KATP channel trafficking: a new paradigm for β-cell stimulus-secretion coupling? | Q38161388 | ||
| Metabolic syndrome and ionic channels in pancreatic beta cells | Q38190193 | ||
| ATP-regulated potassium channels and voltage-gated calcium channels in pancreatic alpha and beta cells: similar functions but reciprocal effects on secretion | Q38218351 | ||
| Persistent hyperinsulinaemic hypoglycaemia in infancy | Q38220429 | ||
| Genetic variations in the pancreatic ATP-sensitive potassium channel, beta-cell dysfunction, and susceptibility to type 2 diabetes | Q38287889 | ||
| ATP-dependent potassium channels and type 2 diabetes mellitus. | Q38316204 | ||
| Organic toxins as tools to understand ion channel mechanisms and structure. | Q38357374 | ||
| Autocrine insulin increases plasma membrane K(ATP) channel via PI3K-VAMP2 pathway in MIN6 cells. | Q38818309 | ||
| Late sodium current (INaL) in pancreatic β-cells. | Q38955138 | ||
| Phosphatidylinositol 4,5-biphosphate (PIP2) modulates interaction of syntaxin-1A with sulfonylurea receptor 1 to regulate pancreatic β-cell ATP-sensitive potassium channels | Q39034153 | ||
| Structurally distinct ligands rescue biogenesis defects of the KATP channel complex via a converging mechanism | Q35199497 | ||
| Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells. | Q35228526 | ||
| G protein modulation of voltage-gated calcium channels | Q35600890 | ||
| Inhibition of Calcium Influx Reduces Dysfunction and Apoptosis in Lipotoxic Pancreatic β-Cells via Regulation of Endoplasmic Reticulum Stress | Q35683568 | ||
| G o 2 G protein mediates galanin inhibitory effects on insulin release from pancreatic β cells | Q35786943 | ||
| Syntaxin-3 Binds and Regulates Both R- and L-Type Calcium Channels in Insulin-Secreting INS-1 832/13 Cells | Q35915373 | ||
| Metabolic regulation of the pancreatic beta-cell ATP-sensitive K+ channel: a pas de deux | Q35961940 | ||
| Adjacent mutations in the gating loop of Kir6.2 produce neonatal diabetes and hyperinsulinism | Q36042053 | ||
| KATP channel interaction with adenine nucleotides. | Q36135749 | ||
| Regulation of the ATP-sensitive K channel Kir6.2 by ATP and PIP(2). | Q36175077 | ||
| Sodium channel inactivation: molecular determinants and modulation | Q36267779 | ||
| Rac-mediated actin remodeling and myosin II are involved in KATP channel trafficking in pancreatic β-cells. | Q36356970 | ||
| Ca2+ influx through L-type Ca2+ channels and Ca2+-induced Ca2+ release regulate cAMP accumulation and Epac1-dependent ERK 1/2 activation in INS-1 cells | Q36385160 | ||
| Metabolic syndrome induces changes in KATP-channels and calcium currents in pancreatic β-cells | Q36394685 | ||
| Na channels and two types of Ca channels in rat pancreatic B cells identified with the reverse hemolytic plaque assay | Q36410071 | ||
| Concerted Trafficking Regulation of Kv2.1 and KATP Channels by Leptin in Pancreatic β-Cells. | Q36444181 | ||
| MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit. | Q36515292 | ||
| Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms | Q36527741 | ||
| Activation of inwardly rectifying potassium (Kir) channels by phosphatidylinosital-4,5-bisphosphate (PIP2): interaction with other regulatory ligands | Q36534343 | ||
| Minireview: Dopaminergic Regulation of Insulin Secretion from the Pancreatic Islet | Q37050350 | ||
| Leptin promotes K ATP channel trafficking by AMPK signaling in pancreatic β-cells | Q37068594 | ||
| Leptin-mediated ion channel regulation: PI3K pathways, physiological role, and therapeutic potential | Q37112040 | ||
| Sodium channel beta1 regulatory subunit deficiency reduces pancreatic islet glucose-stimulated insulin and glucagon secretion. | Q37125999 | ||
| The K(ATP) channel and neonatal diabetes | Q37195674 | ||
| Kir6.2 variant E23K increases ATP-sensitive K+ channel activity and is associated with impaired insulin release and enhanced insulin sensitivity in adults with normal glucose tolerance | Q37267062 | ||
| Channel regulation of glucose sensing in the pancreatic beta-cell | Q37305120 | ||
| Hyperinsulinism in developmental syndromes | Q37417001 | ||
| K(ATP) channelopathies in the pancreas | Q37634376 | ||
| Uncoupling of Cav1.2 from Ca(2+)-induced Ca(2+) release and SK channel regulation in pancreatic β-cells | Q37670109 | ||
| Electrophysiology of islet cells | Q37706216 | ||
| ATP-sensitive potassium channels in health and disease | Q37706219 | ||
| Exocytosis in islet beta-cells | Q37706235 | ||
| Permanent neonatal diabetes due to activating mutations in ABCC8 and KCNJ11. | Q37797962 | ||
| Toxins that modulate ionic channels as tools for exploring insulin secretion | Q37806685 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 341-357 | |
| P577 | publication date | 2016-07-19 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Molecular Pharmacology | Q1943386 |
| P1476 | title | Modulation of Ionic Channels and Insulin Secretion by Drugs and Hormones in Pancreatic Beta Cells | |
| P478 | volume | 90 |
| Q51564986 | A Latin American Perspective on Ion Channels |
| Q47105521 | Anthelminthic activity of glibenclamide on secondary cystic echinococcosis in mice |
| Q64895817 | Blocking Ca2+ Channel β3 Subunit Reverses Diabetes. |
| Q51245240 | Carbamazepine, a beta-cell protecting drug, reduces type 1 diabetes incidence in NOD mice. |
| Q41583846 | Cyanidin Stimulates Insulin Secretion and Pancreatic β-Cell Gene Expression through Activation of l-type Voltage-Dependent Ca2+ Channels |
| Q64945054 | Insulin Release Mechanism Modulated by Toxins Isolated from Animal Venoms: From Basic Research to Drug Development Prospects. |
| Q38652332 | Intermittent hypoxia training in prediabetes patients: Beneficial effects on glucose homeostasis, hypoxia tolerance and gene expression |
| Q60191798 | Lessons from basic pancreatic beta cell research in type-2 diabetes and vascular complications |
Search more.