| scholarly article | Q13442814 |
| P50 | author | Michael J Betenbaugh | Q87747475 |
| P2093 | author name string | Gordon Moore | |
| Dawn Ellis | |||
| Haimanti Dorai | |||
| Subinay Ganguly | |||
| Susanne Corisdeo | |||
| Pam Hawley-Nelson | |||
| Cherylann Kinney | |||
| Matt Chomo | |||
| P2860 | cites work | A trip to the ER: coping with stress | Q29620455 |
| Disruption of higher-order folding by core histone acetylation dramatically enhances transcription of nucleosomal arrays by RNA polymerase III | Q33775383 | ||
| An embarrassment of niches: the many covalent modifications of histones in transcriptional regulation. | Q34290234 | ||
| Advances in animal cell recombinant protein production: GS-NS0 expression system | Q34878044 | ||
| Stability of protein production from recombinant mammalian cells | Q35046175 | ||
| Coupling endoplasmic reticulum stress to the cell death program | Q35649891 | ||
| Mammalian cell factories for efficient and stable protein expression | Q36522392 | ||
| Effects of methotrexate on transfected DNA stability in mammalian cells | Q36714714 | ||
| Loss and stabilization of amplified dihydrofolate reductase genes in mouse sarcoma S-180 cell lines | Q36969824 | ||
| Antigen-specific identification and cloning of hybridomas with a fluorescence-activated cell sorter | Q37328420 | ||
| Therapeutic antibodies for autoimmunity and inflammation | Q37736260 | ||
| Combining high‐throughput screening of caspase activity with anti‐apoptosis genes for development of robust CHO production cell lines | Q39644311 | ||
| Development of mammalian production cell lines expressing CNTO736, a glucagon like peptide-1-MIMETIBODY: factors that influence productivity and product quality | Q39896507 | ||
| The gel microdrop secretion assay: Identification of a low productivity subpopulation arising during the production of human antibody in CHO cells | Q39917985 | ||
| Antibody production | Q40258663 | ||
| Correlation of heavy and light chain mRNA copy numbers to antibody productivity in mouse myeloma production cell lines | Q40316914 | ||
| Optimization of tetracycline-responsive recombinant protein production and effect on cell growth and ER stress in mammalian cells | Q40404414 | ||
| Variation in apoptosis profiles in radiation-induced genomically unstable cell lines. | Q40454191 | ||
| Molecular definition of predictive indicators of stable protein expression in recombinant NS0 myeloma cells | Q40602448 | ||
| Stability of recombinant protein production in the GS-NS0 expression system is unaffected by cryopreservation | Q40672303 | ||
| Amplified gene location in chromosomal DNA affected recombinant protein production and stability of amplified genes. | Q40850083 | ||
| Stabilized, long-term expression of heterodimeric proteins from tricistronic mRNA. | Q40856640 | ||
| Changes during subclone development and ageing of human antibody-producing recombinant CHO cells | Q40949744 | ||
| Analysis of changes during subclone development and ageing of human antibody-producing heterohybridoma cells by northern blot and flow cytometry. | Q40973757 | ||
| Stability of producer hybridoma cell lines after cell sorting: a case study | Q41471892 | ||
| Loss of antibody productivity is highly reproducible in multiple hybridoma subclones | Q41547128 | ||
| Population balance between producing and nonproducing hybridoma clones is very sensitive to serum level, state of inoculum, and medium composition | Q41640248 | ||
| High-level expression of a recombinant antibody from myeloma cells using a glutamine synthetase gene as an amplifiable selectable marker | Q41642360 | ||
| Process development for the production of recombinant antibodies using the glutamine synthetase (GS) system | Q41649450 | ||
| Manipulation of heterogeneous hybridoma cultures for overproduction of monoclonal antibodies | Q41668602 | ||
| Flow cytometric study of hybridoma cell culture: correlation between cell surface fluorescence and IgG production rate | Q41727548 | ||
| Loss of antibody productivity during long-term cultivation of a hybridoma cell line in low serum and serum-free media | Q41737963 | ||
| Characterization of the stability of recombinant protein production in the GS-NS0 expression system | Q43563129 | ||
| A simple method for enriching populations of transfected CHO cells for cells of higher specific productivity | Q44473381 | ||
| Cell cycle kinetics and monoclonal antibody productivity of hybridoma cells during perfusion culture | Q46417362 | ||
| A study on the temperature dependency and time course of the cold capture antibody secretion assay | Q47842229 | ||
| Relationship between loss of heavy chains and the appearance of nonproducing hybridomas | Q47864915 | ||
| Immobilization can improve the stability of hybridoma antibody productivity in serum-free media | Q47869624 | ||
| Chromatin remodeling and transcription. | Q52181964 | ||
| P433 | issue | 4 | |
| P921 | main subject | antibody | Q79460 |
| P304 | page(s) | 1016-1030 | |
| P577 | publication date | 2011-12-01 | |
| P1433 | published in | Biotechnology and Bioengineering | Q4915339 |
| P1476 | title | Early prediction of instability of Chinese hamster ovary cell lines expressing recombinant antibodies and antibody-fusion proteins | |
| P478 | volume | 109 |
| Q47136573 | A chimeric HS4 insulator-scaffold attachment region enhances transgene expression in transfected Chinese hamster ovary cells |
| Q38727469 | A framework to quantify karyotype variation associated with CHO cell line instability at a single-cell level |
| Q91672071 | Attenuated glutamine synthetase as a selection marker in CHO cells to efficiently isolate highly productive stable cells for the production of antibodies and other biologics |
| Q28541134 | Combination of FACS and homologous recombination for the generation of stable and high-expression engineered cell lines |
| Q54962964 | Comprehensive characterization of glutamine synthetase-mediated selection for the establishment of recombinant CHO cells producing monoclonal antibodies. |
| Q38823012 | Deletion of a telomeric region on chromosome 8 correlates with higher productivity and stability of CHO cell lines |
| Q39296661 | Determination of Chinese hamster ovary cell line stability and recombinant antibody expression during long-term culture |
| Q28728948 | Efficient recombinant production in mammalian cells using a novel IR/MAR gene amplification method |
| Q38997531 | Expression of the human cytomegalovirus pentamer complex for vaccine use in a CHO system |
| Q39113686 | Fast identification of reliable hosts for targeted cell line development from a limited-genome screening using combined φC31 integrase and CRE-Lox technologies |
| Q34541494 | Fusion of the Dhfr/Mtx and IR/MAR gene amplification methods produces a rapid and efficient method for stable recombinant protein production |
| Q38743459 | Genetic analyses of Per.C6 cell clones producing a therapeutic monoclonal antibody regarding productivity and long-term stability |
| Q42776621 | Genetic analysis of heterogeneous sub-clones in recombinant Chinese hamster ovary cells. |
| Q36937744 | Impact of Different Promoters on Episomal Vectors Harbouring Characteristic Motifs of Matrix Attachment Regions |
| Q42183859 | Impact of using different promoters and matrix attachment regions on recombinant protein expression level and stability in stably transfected CHO cells. |
| Q38823009 | Improving expression of recombinant human IGF-1 using IGF-1R knockout CHO cell lines |
| Q98892821 | Increased MSX level improves biological productivity and production stability in multiple recombinant GS CHO cell lines |
| Q42220942 | Insertion of core CpG island element into human CMV promoter for enhancing recombinant protein expression stability in CHO cells. |
| Q37652229 | Matrix attachment region combinations increase transgene expression in transfected Chinese hamster ovary cells |
| Q39001735 | Non-viral adeno-associated virus-based platform for stable expression of antibody combination therapeutics |
| Q91847444 | Optimization of Protein Expression in Mammalian Cells |
| Q48090292 | Optimized Selection Marker and CHO Host Cell Combinations for Generating High Monoclonal Antibody Producing Cell Lines. |
| Q91723955 | Overcoming genetic heterogeneity in industrial fermentations |
| Q92754095 | SPLICELECT™: an adaptable cell surface display technology based on alternative splicing allowing the qualitative and quantitative prediction of secreted product at a single-cell level |
| Q35820624 | Transcriptome study and identification of potential marker genes related to the stable expression of recombinant proteins in CHO clones. |
| Q38410973 | Ubiquitous Chromatin Opening Elements (UCOEs) effect on transgene position and expression stability in CHO cells following methotrexate (MTX) amplification |
| Q35022542 | Using molecular markers to characterize productivity in Chinese hamster ovary cell lines |
| Q38858726 | miR-143 targets MAPK7 in CHO cells and induces a hyperproductive phenotype to enhance production of difficult-to-express proteins |
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