Estrogen Attenuates Local Inflammasome Expression and Activation after Spinal Cord Injury

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Estrogen Attenuates Local Inflammasome Expression and Activation after Spinal Cord Injury is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1074220610
P356DOI10.1007/S12035-017-0400-2
P698PubMed publication ID28127698

P50authorArash ZaminyQ56811226
Malek Masoud AnsarQ58023837
P2093author name stringCordian Beyer
Markus Kipp
Gholamreza Hassanzadeh
Adib Zendedel
Alexander Slowik
Pardes Habib
Fabian Mönnink
P2860cites workEstrogen receptor-α and -β immunoreactivity and mRNA in neurons of sensory and autonomic ganglia and spinal cordQ64460582
Glucocorticoid regulation of motoneuronal parameters in rats with spinal cord injuryQ77929613
Effect of 17beta-estradiol on signal transduction pathways and secondary damage in experimental spinal cord traumaQ80808587
The inflammasomesQ24304087
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 miceQ24604235
IL-1β signaling promotes CNS-intrinsic immune control of West Nile virus infectionQ27340022
The other side of progestins: effects in the brainQ28067508
The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B releaseQ28250608
Inflammatory caspases and inflammasomes: master switches of inflammationQ28263855
Cryopyrin activates the inflammasome in response to toxins and ATPQ28291313
G-protein coupled estrogen receptor 1 mediated estrogenic neuroprotection against spinal cord injuryQ28567284
Rapid co-release of interleukin 1beta and caspase 1 in spinal cord inflammationQ28574292
Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injuryQ28582906
Temporal changes in cell marker expression and cellular infiltration in a controlled cortical impact model in adult male C57BL/6 miceQ28728862
Activation and regulation of the inflammasomesQ29615664
Sex and hormonal variations in the development of at-level allodynia in a rat chronic spinal cord injury model.Q30431772
Postinjury administration of 17β-estradiol induces protection in the gray and white matter with associated functional recovery after cervical spinal cord injury in male ratsQ33631344
Spinal cord injury causes a wide-spread, persistent loss of Kir4.1 and glutamate transporter 1: benefit of 17 beta-oestradiol treatmentQ33773510
Effect of endogenous androgens on 17beta-estradiol-mediated protection after spinal cord injury in male ratsQ33841455
Estradiol inhibits ongoing autoimmune neuroinflammation and NFkappaB-dependent CCL2 expression in reactive astrocytesQ33929484
The inflammasome: first line of the immune response to cell stressQ33998873
Recent advances in the pharmacologic treatment of spinal cord injuryQ34518608
Biological role of estrogen and estrogen receptorsQ34571725
Triggering of inflammasome by aggregated α-synuclein, an inflammatory response in synucleinopathiesQ34576478
Postinjury estrogen treatment of chronic spinal cord injury improves locomotor function in ratsQ35080116
NLRP3 Inflammasome Is Expressed and Functional in Mouse Brain Microglia but Not in AstrocytesQ35668969
IL-18: a key player in neuroinflammation and neurodegeneration?Q36197319
Non-alcoholic fatty liver disease induces signs of Alzheimer's disease (AD) in wild-type mice and accelerates pathological signs of AD in an AD modelQ36428502
Heme oxygenase-1 promotes neuron survival through down-regulation of neuronal NLRP1 expression after spinal cord injuryQ36634684
Targeting estrogen receptor β in microglia and T cells to treat experimental autoimmune encephalomyelitisQ36653657
Targeting inflammation as a treatment modality for neuropathic pain in spinal cord injury: a randomized clinical trialQ37018248
Rat substrains differ in the magnitude of spontaneous locomotor recovery and in the development of mechanical hypersensitivity after experimental spinal cord injuryQ37244603
Impact of sex steroids on neuroinflammatory processes and experimental multiple sclerosisQ37459641
Actions of estrogens on glial cells: Implications for neuroprotectionQ37612163
Long-term cerebral cortex protection and behavioral stabilization by gonadal steroid hormones after transient focal hypoxiaQ37983331
Neuroprotection by gonadal steroid hormones in acute brain damage requires cooperation with astroglia and microgliaQ38063715
Inflammasomes in the CNS.Q38176535
Sex steroids and neuroprotection in spinal cord injury: a review of preclinical investigationsQ38179772
Quantitative assessment of immune cells in the injured spinal cord tissue by flow cytometry: a novel use for a cell purification methodQ38352732
Inflammasomes are neuroprotective targets for sex steroidsQ38369380
Female sex steroids and glia cells: Impact on multiple sclerosis lesion formation and fine tuning of the local neurodegenerative cellular networkQ38677316
Neuroinflammation: the devil is in the detailsQ38779873
Sex steroid hormone-mediated functional regulation of microglia-like BV-2 cells during hypoxiaQ39136264
Cell volume regulation modulates NLRP3 inflammasome activationQ39278343
Early Spinal Surgery Following Thoracolumbar Spinal Cord Injury: Process of Care From Trauma to TheaterQ39351100
17beta-estradiol and progesterone prevent cuprizone provoked demyelination of corpus callosum in male miceQ40025304
17beta-estradiol protects oligodendrocytes from cytotoxicity induced cell deathQ40566485
Activation and Regulation of NLRP3 Inflammasome by Intrathecal Application of SDF-1a in a Spinal Cord Injury ModelQ40941919
Gonadal steroids prevent cell damage and stimulate behavioral recovery after transient middle cerebral artery occlusion in male and female ratsQ42483216
Selective regulation of growth factor expression in cultured cortical astrocytes by neuro-pathological toxinsQ43865805
Estrogen attenuated markers of inflammation and decreased lesion volume in acute spinal cord injury in ratsQ46676371
Effect of 17beta-estradiol on functional outcome, release of cytokines, astrocyte reactivity and inflammatory spreading after spinal cord injury in male ratsQ46721526
Hypoxia-induced gene expression of aquaporin-4, cyclooxygenase-2 and hypoxia-inducible factor 1α in rat cortical astroglia is inhibited by 17β-estradiol and progesteroneQ46911933
NLRP3 inflammasome activation mediates estrogen deficiency-induced depression- and anxiety-like behavior and hippocampal inflammation in miceQ47577144
Membrane-associated estrogen receptor and caveolin-1 are present in central nervous system myelin and oligodendrocyte plasma membranes.Q48019697
Stromal cell-derived factor-1 alpha (SDF-1α) improves neural recovery after spinal cord contusion in ratsQ48425306
Omega-3 polyunsaturated fatty acids ameliorate neuroinflammation and mitigate ischemic stroke damage through interactions with astrocytes and microgliaQ48425876
17β-Estradiol inhibits apoptotic cell death of oligodendrocytes by inhibiting RhoA-JNK3 activation after spinal cord injuryQ48472429
Demonstration of steroid hormone receptors and steroid action in primary cultures of rat glial cellsQ48516492
Changes in spinal cord injury-induced gene expression in rat are strain-dependent.Q51252952
Poststroke Inflammasome Expression and Regulation in the Peri-Infarct Area by Gonadal Steroids after Transient Focal Ischemia in the Rat Brain.Q52149986
NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients.Q53413551
A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord InjuryQ56775114
P921main subjectinflammasome complexQ412405
P577publication date2017-01-27
P1433published inMolecular NeurobiologyQ15716645
P1476titleEstrogen Attenuates Local Inflammasome Expression and Activation after Spinal Cord Injury

Reverse relations

cites work (P2860)
Q9285736817β-Estradiol Regulates Glucose Metabolism and Insulin Secretion in Rat Islet β Cells Through GPER and Akt/mTOR/GLUT2 Pathway
Q5496760517β-Estradiol Regulates Microglia Activation and Polarization in the Hippocampus Following Global Cerebral Ischemia.
Q64950592A Novel Sex-Dependent Target for the Treatment of Postoperative Pain: The NLRP3 Inflammasome.
Q99622697CRID3, a blocker of apoptosis associated speck like protein containing a card, ameliorates murine spinal cord injury by improving local immune microenvironment
Q64255361Carbon monoxide releasing molecule-3 alleviates neuron death after spinal cord injury via inflammasome regulation
Q53410201Combined effects of rat Schwann cells and 17β-estradiol in a spinal cord injury model.
Q62734382Hypoxia Induces Astrocyte-Derived Lipocalin-2 in Ischemic Stroke
Q90077286Molecular mechanisms and cellular events involved in the neuroprotective actions of estradiol. Analysis of sex differences
Q104289751NIMA-related kinase 7 amplifies NLRP3 inflammasome pro-inflammatory signaling in microglia/macrophages and mice models of spinal cord injury
Q55505620Potential immunotherapies for traumatic brain and spinal cord injury.
Q90024104Prognosis Evaluation Using 18F-Alfatide II PET in a Rat Model of Spinal Cord Injury Treated With Estrogen
Q55227175Valproic acid attenuates traumatic spinal cord injury-induced inflammation via STAT1 and NF-κB pathway dependent of HDAC3.
Q90910925Vastly extended drug release from poly(pro-17β-estradiol) materials facilitates in vitro neurotrophism and neuroprotection
Q58692011α1-antitrypsin mitigates NLRP3-inflammasome activation in amyloid β-stimulated murine astrocytes

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