Hypoxia Induces Astrocyte-Derived Lipocalin-2 in Ischemic Stroke

scientific article published on 13 March 2019

Hypoxia Induces Astrocyte-Derived Lipocalin-2 in Ischemic Stroke is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3390/IJMS20061271
P953full work available at URLhttps://www.mdpi.com/1422-0067/20/6/1271
P932PMC publication ID6471434
P698PubMed publication ID30871254

P50authorRalf WeiskirchenQ51753160
Cordian BeyerQ88008605
Tim ClarnerQ90141242
P2093author name stringCordian Beyer
Adib Zendedel
Miriam Scheld
Tim Clarner
Fatemeh Ranjbar Taklimie
Natalie Gasterich
P2860cites workNeutrophil granulocytes in cerebral ischemia - Evolution from killers to key playersQ28067182
Lipocalin 2 (LCN2) Expression in Hepatic Malfunction and TherapyQ28068137
Lipocalin2 promotes invasion, tumorigenicity and gemcitabine resistance in pancreatic ductal adenocarcinomaQ28484227
Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injuryQ28591880
The immunology of stroke: from mechanisms to translationQ29620066
CNS-disease affecting the heart: brain-heart disordersQ33164526
Estrogen Attenuates Local Inflammasome Expression and Activation after Spinal Cord InjuryQ33364651
Spatiotemporal Changes in P-glycoprotein Levels in Brain and Peripheral Tissues Following Ischemic Stroke in RatsQ33583533
Neurotoxic reactive astrocytes are induced by activated microgliaQ33602850
Lipocalin-2 protein deficiency ameliorates experimental autoimmune encephalomyelitis: the pathogenic role of lipocalin-2 in the central nervous system and peripheral lymphoid tissuesQ33761191
Lipocalin-2 Acts as a Neuroinflammatogen in Lipopolysaccharide-injected MiceQ33787342
Circulatory Levels of C-X-C Motif Chemokine Ligands 1, 9, and 10 Are Elevated in Patients with Ischemic StrokeQ33794366
Neuronal production of lipocalin-2 as a help-me signal for glial activationQ34004153
Lipocalin-2 deficiency attenuates neuroinflammation and brain injury after transient middle cerebral artery occlusion in miceQ34018660
Lipocalin 2 and Blood-Brain Barrier Disruption in White Matter after Experimental Subarachnoid Hemorrhage.Q52147990
Poststroke Inflammasome Expression and Regulation in the Peri-Infarct Area by Gonadal Steroids after Transient Focal Ischemia in the Rat Brain.Q52149986
Ginkgo biloba Extract Inhibits Astrocytic Lipocalin-2 Expression and Alleviates Neuroinflammatory Injury via the JAK2/STAT3 Pathway After Ischemic Brain Stroke.Q55292589
The regulatory role of Toll-like receptors after ischemic stroke: neurosteroids as TLR modulators with the focus on TLR2/4Q58093823
Molecular Communication of a Dying Neuron in StrokeQ58716193
Multicellular Crosstalk Between Exosomes and the Neurovascular Unit After Cerebral Ischemia. Therapeutic ImplicationsQ59136421
Lipocalin 2 Plays an Immunomodulatory Role and Has Detrimental Effects after Spinal Cord InjuryQ63915714
Experimental stroke induces massive, rapid activation of the peripheral immune systemQ81112631
CXCL10 triggers early microglial activation in the cuprizone modelQ86843743
[Astrocytes in ischemic stroke - a potential target for neuroprotective strategies]Q87158649
Impact of steroid hormones E2 and P on the NLRP3/ASC/Casp1 axis in primary mouse astroglia and BV-2 cells after in vitro hypoxiaQ88717155
Predicting functional outcome of ischemic stroke patients in Romania based on plasma CRP, sTNFR-1, D-Dimers, NGAL and NSE measured using a biochip arrayQ89173742
Microglia-Astrocyte Crosstalk: An Intimate Molecular ConversationQ89185541
Roles of blood-brain barrier integrins and extracellular matrix in strokeQ93271466
Cerebral ischemic stroke: cellular fate and therapeutic opportunitiesQ93369036
Astrocyte-neuron lactate transport is required for long-term memory formationQ34025968
Lipocalin-2 expressed in innate immune cells is an endogenous inhibitor of inflammation in murine nephrotoxic serum nephritisQ34825843
Lipocalin-2 Is a chemokine inducer in the central nervous system: role of chemokine ligand 10 (CXCL10) in lipocalin-2-induced cell migrationQ35626188
Lipocalin-2 as an Infection-Related Biomarker to Predict Clinical Outcome in Ischemic StrokeQ36010841
Role of lipocalin-2 in brain injury after intracerebral hemorrhage.Q36267469
Astrocyte-Derived Pentraxin 3 Supports Blood-Brain Barrier Integrity Under Acute Phase of StrokeQ36739655
Astrocyte barriers to neurotoxic inflammationQ37597818
Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegenerationQ37640563
Stroke and the immune system: from pathophysiology to new therapeutic strategiesQ37867782
Protein microarray analysis identifies key cytokines associated with malignant middle cerebral artery infarction.Q38429567
Lipocalin-2 in the Inflammatory Activation of Brain AstrocytesQ38537863
Lipocalin-2: A Master Mediator of Intestinal and Metabolic InflammationQ38755861
Lipocalin-2 as a therapeutic target for brain injury: An astrocentric perspectiveQ38833765
Lipocalin2 as a plasma marker for tumors with hypoxic regions.Q38932870
Regulation of hypoxia-induced inflammatory responses and M1-M2 phenotype switch of primary rat microglia by sex steroidsQ39069957
Lipocalin 2: An Emerging Player in Iron Homeostasis and InflammationQ39382867
Lipocalin-2 protects the brain during inflammatory conditionsQ40972596
Novel Therapeutic Effects of Leonurine On Ischemic Stroke: New Mechanisms of BBB IntegrityQ41037865
Lipocalin-2 released in response to cerebral ischaemia mediates reperfusion injury in miceQ41852055
Gonadal steroids prevent cell damage and stimulate behavioral recovery after transient middle cerebral artery occlusion in male and female ratsQ42483216
Microglia proliferation is regulated by hydrogen peroxide from NADPH oxidaseQ42488897
TTC staining of damaged brain areas after MCA occlusion in the rat does not constrict quantitative gene and protein analysesQ43197570
Differential subnetwork of chemokines/cytokines in human, mouse, and rat brain cells after oxygen-glucose deprivationQ46529328
Hypoxia-induced gene expression of aquaporin-4, cyclooxygenase-2 and hypoxia-inducible factor 1α in rat cortical astroglia is inhibited by 17β-estradiol and progesteroneQ46911933
Rosiglitazone as a Modulator of TLR4 and TLR3 Signaling Pathways in Rat Primary Neurons and AstrocytesQ47232222
Astrocytes and ischemic toleranceQ47923779
Inflammasome: Its role in traumatic brain and spinal cord injury.Q47963725
Impact of Inflammation on the Blood-Neural Barrier and Blood-Nerve Interface: From Review to Therapeutic PreviewQ47971672
Astrocyte-derived lipocalin-2 mediates hippocampal damage and cognitive deficits in experimental models of vascular dementiaQ48329233
Omega-3 polyunsaturated fatty acids ameliorate neuroinflammation and mitigate ischemic stroke damage through interactions with astrocytes and microgliaQ48425876
Neurodegeneration Triggers Peripheral Immune Cell Recruitment into the ForebrainQ48945835
Perspectives in Lipocalin-2: Emerging Biomarker for Medical Diagnosis and Prognosis for Alzheimer's DiseaseQ49165016
Serum levels of adipokines and cytokines in psoriasis patients: a systematic review and meta-analysis.Q49249983
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue6
P407language of work or nameEnglishQ1860
P921main subjecthypoxiaQ105688
astrocyteQ502961
P304page(s)1271
P577publication date2019-01-01
2019-03-13
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleHypoxia Induces Astrocyte-Derived Lipocalin-2 in Ischemic Stroke
P478volume20

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cites work (P2860)
Q89454276Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia
Q98467010LncRNA MACC1-AS1 attenuates microvascular endothelial cell injury and promotes angiogenesis under hypoxic conditions via modulating miR-6867-5p/TWIST1 in human brain microvascular endothelial cells

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