Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study.

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Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/ANNONC/MDP343
P932PMC publication ID2826096
P698PubMed publication ID19767314
P5875ResearchGate publication ID26824777

P50authorMilena VitaliQ54263896
Salvatore SienaQ28321703
Stefano CascinuQ38359621
P2093author name stringM Danova
L Crinò
E Bajetta
S Salvagni
S Del Prete
I Schiavetto
P2860cites workRadiotherapy plus concomitant and adjuvant temozolomide for glioblastomaQ27860910
The Charing Cross Hospital experience with temozolomide in patients with gliomasQ48836301
Survival after brain metastases from breast cancer in the trastuzumab era.Q48962445
Incidence Proportions of Brain Metastases in Patients Diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance SystemQ57407206
Central Nervous System Metastases in HER-2 Positive Metastatic Breast Cancer Patients Treated with Trastuzumab: Incidence, Survival, and Risk FactorsQ58849618
Reporting results of cancer treatmentQ29620070
Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. Temodal Brain Tumor GroupQ30584392
Validation of the RTOG recursive partitioning analysis (RPA) classification for brain metastasesQ30881871
Identification of prognostic factors in patients with brain metastases: a review of 1292 patientsQ33177750
Concomitant treatment of brain metastasis with whole brain radiotherapy [WBRT] and temozolomide [TMZ] is active and improves quality of lifeQ33270398
A phase II trial of temozolomide for patients with recurrent or progressive brain metastasesQ33339923
Front-line paclitaxel/cisplatin-based chemotherapy in brain metastases from non-small-cell lung cancer.Q33345489
Marked inactivation of O6-alkylguanine-DNA alkyltransferase activity with protracted temozolomide schedulesQ33347264
Temozolomide for the treatment of brain metastases associated with metastatic melanoma: a phase II studyQ33361043
Temozolomide (TMZ) combined with cisplatin (CDDP) in patients with brain metastases from solid tumors: a Hellenic Cooperative Oncology Group (HeCOG) Phase II studyQ33365077
Temozolomide in metastatic breast cancer (MBC): a phase II trial of the National Cancer Institute of Canada - Clinical Trials Group (NCIC-CTG).Q33370672
Topotecan in the treatment of brain metastases. A phase II study of GOIM (Gruppo Oncologico dell'Italia Meridionale).Q33371852
Phase II study of temozolomide and concomitant whole-brain radiotherapy in patients with brain metastases from solid tumorsQ33375710
Mitoxantrone plus vinorelbine in pretreated patients with metastatic breast cancerQ33377758
Unmasking a killer: DNA O(6)-methylguanine and the cytotoxicity of methylating agentsQ33892805
Temozolomide: a novel oral alkylating agentQ34734267
The role of topotecan in the treatment of brain metastasesQ35644836
Current management of brain metastases, with a focus on systemic optionsQ36246183
Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: phase II study from gruppo italiano cooperativo di neuro-oncologia (GICNO).Q36611825
Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trialsQ36857456
Multidisciplinary management of brain metastasesQ36900730
Radiotherapy and radiosensitizers in the treatment of glioblastoma multiforme.Q37054146
Differential radiosensitizing potential of temozolomide in MGMT promoter methylated glioblastoma multiforme cell lines.Q40060814
Phase II study of temozolomide in heavily pretreated cancer patients with brain metastasesQ43573415
First-line chemotherapy with vinorelbine, gemcitabine, and carboplatin in the treatment of brain metastases from non-small-cell lung cancer: a phase II study.Q44003032
Phase II randomized trial of temozolomide and concurrent radiotherapy in patients with brain metastasesQ44119212
Gefitinib in patients with brain metastases from non-small-cell lung cancer: a prospective trialQ44942613
Phase III study of efaproxiral as an adjunct to whole-brain radiation therapy for brain metastasesQ46825143
CNS response after erlotinib therapy in a patient with metastatic NSCLC with an EGFR mutationQ46979383
Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent gliomaQ48090038
A phase I/II trial of topotecan and radiation therapy for brain metastases in patients with solid tumorsQ48231603
Front-line chemotherapy with cisplatin and etoposide for patients with brain metastases from breast carcinoma, nonsmall cell lung carcinoma, or malignant melanoma: a prospective studyQ48244398
Dose-intensified bi-weekly temozolomide in patients with asymptomatic brain metastases from malignant melanoma: a phase II DeCOG/ADO study.Q48411500
Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanineQ48479768
Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma.Q48514261
P433issue3
P921main subjectlung cancerQ47912
breast cancerQ128581
neurosurgeryQ188449
temozolomideQ425088
brain metastasisQ1620196
multicenter clinical trialQ6934595
P304page(s)655-661
P577publication date2009-09-18
P1433published inAnnals of OncologyQ326122
P1476titleDose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study
P478volume21

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cites work (P2860)
Q30412393A nanoparticle carrying the p53 gene targets tumors including cancer stem cells, sensitizes glioblastoma to chemotherapy and improves survival
Q38066590Brain metastases from prostate cancer: an emerging clinical problem with implications for the future therapeutic scenario.
Q38222247Brain metastasis: new opportunities to tackle therapeutic resistance
Q37573461Cancer and the metastatic substrate
Q38792519Challenges in the treatment of hormone receptor-positive, HER2-negative metastatic breast cancer with brain metastases
Q82794554Cisplatin and temozolomide combination in the treatment of leptomeningeal carcinomatosis from ethmoid sinus intestinal-type adenocarcinoma
Q48806386Clinical trial design in brain metastasis: approaches for a unique patient population
Q38369616Combined treatment for non-small cell lung cancer and breast cancer patients with brain metastases with whole brain radiotherapy and temozolomide: a systematic review and meta-analysis
Q38036217Combining stereotactic radiosurgery and systemic therapy for brain metastases: a potential role for temozolomide
Q33696559Current approaches to the treatment of metastatic brain tumours
Q36820588Development of a preclinical therapeutic model of human brain metastasis with chemoradiotherapy.
Q39637384Effect of chemotherapy on survival after whole brain radiation therapy for brain metastases: a single-center retrospective analysis
Q26824799Emerging treatment options for the management of brain metastases in patients with HER2-positive metastatic breast cancer
Q85112989Implications of modern anticancer therapies for palliative care concepts
Q87597521Leptomeningeal Metastases
Q36939922Melanoma Brain Metastasis Pseudoprogression after Pembrolizumab Treatment.
Q26995622Melanoma brain metastases: an unmet challenge in the era of active therapy
Q54942365Meta-analysis of whole-brain radiotherapy plus temozolomide compared with whole-brain radiotherapy for the treatment of brain metastases from non-small-cell lung cancer.
Q48121721Metastatic melanoma to the brain: surgery and radiation is still the standard of care
Q35584731Neoplastic meningitis from solid tumors: new diagnostic and therapeutic approaches.
Q38067340Optimal management of brain metastases from breast cancer. Issues and considerations
Q28072442Perillyl Alcohol and Its Drug-Conjugated Derivatives as Potential Novel Methods of Treating Brain Metastases
Q48695471Phase I study of bendamustine with concurrent whole brain radiation therapy in patients with brain metastases from solid tumors
Q34372972Phase I trial of hydroxychloroquine with dose-intense temozolomide in patients with advanced solid tumors and melanoma
Q48471112Phase II randomized study of whole-brain radiation therapy with or without concurrent temozolomide for brain metastases from breast cancer
Q37641250Phase II trial of patupilone in patients with brain metastases from breast cancer
Q33401308Phase II trial of temozolomide for leptomeningeal metastases in patients with solid tumors.
Q33909294Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner
Q33777436Progress in the biological understanding and management of breast cancer-associated central nervous system metastases
Q48401767Protracted low dose of oral vinorelbine and temozolomide with whole-brain radiotherapy in the treatment for breast cancer patients with brain metastases
Q30239901Systemic therapy of brain metastases: non-small cell lung cancer, breast cancer, and melanoma
Q39652258Systemic treatment of brain metastases in HER2-positive breast cancer: current status and future directions
Q37576025Temozolomide for treatment of brain metastases: A review of 21 clinical trials
Q34762265The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas
Q38532696The current management of brain metastasis in melanoma: a focus on riluzole
Q90474060The impact of current treatment modalities on the outcomes of patients with melanoma brain metastases: A systematic review
Q58023833Therapie von Hirnmetastasen und Meningeosis neoplastica
Q85185650Topotecan and ifosfamide systemic chemotherapy for CNS involvement of solid tumors
Q36057858Treatment of Breast Cancer Brain Metastases
Q38155202Treatment of brain metastases from HER-2-positive breast cancer: current status and new concepts
Q54509712[Progress of treatments in non-small cell lung cancer with brain metastases].

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