| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2008PLoSO...3.3872P |
| P356 | DOI | 10.1371/JOURNAL.PONE.0003872 |
| P932 | PMC publication ID | 2592702 |
| P698 | PubMed publication ID | 19060956 |
| P5875 | ResearchGate publication ID | 23628023 |
| P50 | author | Adriano Aguzzi | Q375410 |
| Roman Jerala | Q5344 | ||
| Kurt Wüthrich | Q110957 | ||
| Simone Hornemann | Q57587562 | ||
| Christina J. Sigurdson | Q90769289 | ||
| P2093 | author name string | Mike Scott | |
| Michael N G James | |||
| Magdalini Polymenidou | |||
| Martin Vey | |||
| Yong-Zhong Shi | |||
| Rita Moos | |||
| Anne Bellon | |||
| Iva Hafner-Bratkovic | |||
| Nat Kav | |||
| Bill Yajima | |||
| Graciela Garen | |||
| P2860 | cites work | Selection, characterization and x-ray structure of anti-ampicillin single-chain Fv fragments from phage-displayed murine antibody libraries | Q27632404 |
| Prion protein interaction with the C-terminal SH3 domain of Grb2 studied using NMR and optical spectroscopy | Q28509226 | ||
| Mapping the prion protein using recombinant antibodies | Q32003051 | ||
| Conservation of the cellular gene encoding the scrapie prion protein | Q36093945 | ||
| Prion protein expression in different species: analysis with a panel of new mAbs | Q36222036 | ||
| Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication | Q36455926 | ||
| Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies | Q36663046 | ||
| Molecular location of a species-specific epitope on the hamster scrapie agent protein | Q36701217 | ||
| Circumventing tolerance to generate autologous monoclonal antibodies to the prion protein | Q36806239 | ||
| Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system | Q36846512 | ||
| Targeting by affinity-matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform | Q36889715 | ||
| Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins | Q36919750 | ||
| Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection. | Q37569845 | ||
| Characterization of the prion protein 3F4 epitope and its use as a molecular tag. | Q40103958 | ||
| Generation of monoclonal antibodies against prion proteins with an unconventional nucleic acid-based immunization strategy. | Q40929052 | ||
| Prion (PrPSc)-specific epitope defined by a monoclonal antibody | Q42816365 | ||
| Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein | Q43522858 | ||
| Selective and efficient immunoprecipitation of the disease-associated form of the prion protein can be mediated by nonspecific interactions between monoclonal antibodies and scrapie-associated fibrils | Q44894424 | ||
| Epitope mapping of the Syrian hamster prion protein utilizing chimeric and mutant genes in a vaccinia virus expression system | Q45859232 | ||
| Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions | Q48479400 | ||
| Antibodies to a scrapie prion protein | Q48635549 | ||
| Coexistence of multiple PrPSc types in individuals with Creutzfeldt-Jakob disease | Q48691137 | ||
| Competition BIAcore for measuring true affinities: large differences from values determined from binding kinetics. | Q52310418 | ||
| Binding of disease-associated prion protein to plasminogen. | Q52541671 | ||
| Prion strain discrimination using luminescent conjugated polymers | Q57083638 | ||
| Monoclonal antibodies to the cellular and scrapie prion proteins | Q70299710 | ||
| Human prion proteins expressed in Escherichia coli and purified by high-affinity column refolding | Q73966978 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | antibody | Q79460 |
| prion protein family | Q24724413 | ||
| P304 | page(s) | e3872 | |
| P577 | publication date | 2008-12-08 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes | |
| P478 | volume | 3 |
| Q57061905 | A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity |
| Q33675812 | A proposed mechanism for the promotion of prion conversion involving a strictly conserved tyrosine residue in the β2-α2 loop of PrPC. |
| Q40564182 | Activation of microglia by retroviral infection correlates with transient clearance of prions from the brain but does not change incubation time. |
| Q58756018 | Advanced fabrication of biosensor on detection of Glypican-1 using S-Acetylmercaptosuccinic anhydride (SAMSA) modification of antibody |
| Q53680677 | Atypical prion protein conformation in familial prion disease with PRNP P105T mutation. |
| Q34094490 | Axonal prion protein is required for peripheral myelin maintenance |
| Q28480480 | Biochemical properties of highly neuroinvasive prion strains |
| Q35076872 | Biological effects and use of PrPSc- and PrP-specific antibodies generated by immunization with purified full-length native mouse prions |
| Q99565667 | Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake |
| Q36347803 | Characterization of conformation-dependent prion protein epitopes |
| Q35205070 | Characterization of four new monoclonal antibodies against the distal N-terminal region of PrP(c). |
| Q34307252 | Comparison of 2 synthetically generated recombinant prions |
| Q64275935 | Complement 3-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia |
| Q39630174 | Conditional Expression of Full-Length Humanized Anti-Prion Protein Antibodies in Chinese Hamster Ovary Cells |
| Q36078399 | Copper-induced structural conversion templates prion protein oligomerization and neurotoxicity. |
| Q35539075 | Crystallization and preliminary X-ray diffraction analysis of prion protein bound to the Fab fragment of the POM1 antibody |
| Q36274319 | Cystatin F is a biomarker of prion pathogenesis in mice |
| Q37547167 | De novo prion aggregates trigger autophagy in skeletal muscle |
| Q28486278 | Defining the conformational features of anchorless, poorly neuroinvasive prions |
| Q35907379 | Differential Toxicity of Antibodies to the Prion Protein |
| Q36243697 | Disease-associated prion protein in neural and lymphoid tissues of mink (Mustela vison) inoculated with transmissible mink encephalopathy. |
| Q33892707 | Dynamic diagnosis of familial prion diseases supports the β2-α2 loop as a universal interference target |
| Q34161546 | Engulfment of cerebral apoptotic bodies controls the course of prion disease in a mouse strain-dependent manner |
| Q90076904 | Enhanced detection of prion infectivity from blood by preanalytical enrichment with peptoid-conjugated beads |
| Q33588967 | Enhanced neuroinvasion by smaller, soluble prions |
| Q37818890 | Experimental approaches to the interaction of the prion protein with nucleic acids and glycosaminoglycans: Modulators of the pathogenic conversion |
| Q33725612 | Experimental verification of a traceback phenomenon in prion infection |
| Q33501189 | Functionally relevant domains of the prion protein identified in vivo |
| Q51736170 | Generation of novel neuroinvasive prions following intravenous challenge. |
| Q30468679 | Globular domain of the prion protein needs to be unlocked by domain swapping to support prion protein conversion |
| Q30639674 | Human prion protein sequence elements impede cross-species chronic wasting disease transmission. |
| Q47099606 | Inhibition of group-I metabotropic glutamate receptors protects against prion toxicity. |
| Q27319284 | Intraperitoneal Infection of Wild-Type Mice with Synthetically Generated Mammalian Prion |
| Q33608651 | Liposome-siRNA-peptide complexes cross the blood-brain barrier and significantly decrease PrP on neuronal cells and PrP in infected cell cultures |
| Q34388480 | Lymphotoxin, but not TNF, is required for prion invasion of lymph nodes |
| Q38877330 | Modifiers of prion protein biogenesis and recycling identified by a highly parallel endocytosis kinetics assay |
| Q37993988 | Nanopore analysis: An emerging technique for studying the folding and misfolding of proteins |
| Q27316068 | Neurodegeneration and unfolded-protein response in mice expressing a membrane-tethered flexible tail of PrP |
| Q36351017 | Novel epitopes identified by anti-PrP monoclonal antibodies produced following immunization of Prnp0/0 Balb/cJ mice with purified scrapie prions |
| Q37732620 | Peripheral administration of a humanized anti-PrP antibody blocks Alzheimer's disease Aβ synaptotoxicity |
| Q39407430 | Persistent retroviral infection with MoMuLV influences neuropathological signature and phenotype of prion disease |
| Q36003595 | Polythiophenes inhibit prion propagation by stabilizing prion protein (PrP) aggregates |
| Q30399619 | Post-translational modifications in PrP expand the conformational diversity of prions in vivo |
| Q33916451 | PrP(Sc)-specific antibodies with the ability to immunodetect prion oligomers. |
| Q48245277 | PrP-specific camel antibodies with the ability to immunodetect intracellular prion protein |
| Q59793162 | Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients |
| Q36005171 | Prion infection promotes extensive accumulation of α-synuclein in aged human α-synuclein transgenic mice |
| Q35566835 | Prion infections and anti-PrP antibodies trigger converging neurotoxic pathways. |
| Q53689011 | Prion infectivity is encoded exclusively within the structure of proteinase K-resistant fragments of synthetically generated recombinant PrPSc. |
| Q27316552 | Prion pathogenesis in the absence of NLRP3/ASC inflammasomes |
| Q34468979 | Prion pathogenesis is faithfully reproduced in cerebellar organotypic slice cultures. |
| Q60049338 | Prion pathogenesis is unaltered in a mouse strain with a permeable blood-brain barrier |
| Q36381643 | Prion pathogenesis is unaltered in the absence of SIRPα-mediated "don't-eat-me" signaling |
| Q34233877 | Prion protein and Abeta-related synaptic toxicity impairment |
| Q27316704 | Prion protein-specific antibodies that detect multiple TSE agents with high sensitivity |
| Q34423386 | Prion protein-specific antibodies-development, modes of action and therapeutics application |
| Q34185289 | Prion strain interactions are highly selective |
| Q54224345 | Prions, prionoids and protein misfolding disorders. |
| Q33506629 | Repetitive immunization enhances the susceptibility of mice to peripherally administered prions |
| Q37184038 | Role of proteolytic activation of protein kinase Cδ in the pathogenesis of prion disease |
| Q37322155 | SIRPα polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells |
| Q40136054 | Self-propagating, protease-resistant, recombinant prion protein conformers with or without in vivo pathogenicity. |
| Q38139218 | Single-chain fragment variable passive immunotherapies for neurodegenerative diseases |
| Q35211687 | Single-molecule imaging reveals that small amyloid-β1-42 oligomers interact with the cellular prion protein (PrP(C)) |
| Q35499036 | Spongiform encephalopathy in transgenic mice expressing a point mutation in the β2-α2 loop of the prion protein |
| Q36745030 | Strictly co-isogenic C57BL/6J-Prnp-/- mice: A rigorous resource for prion science |
| Q52602016 | Structural and mechanistic aspects influencing the ADAM10-mediated shedding of the prion protein. |
| Q91800637 | Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion |
| Q36055574 | Structure of the β2-α2 loop and interspecies prion transmission |
| Q28592095 | Tetracysteine-tagged prion protein allows discrimination between the native and converted forms |
| Q33793628 | The N-terminus of the prion protein is a toxic effector regulated by the C-terminus. |
| Q27677854 | The crystal structure of an octapeptide repeat of the Prion protein in complex with a Fab fragment of the POM2 antibody |
| Q28473010 | The octarepeat region of the prion protein is conformationally altered in PrP(Sc) |
| Q28511844 | The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6 |
| Q34682177 | The role of the NADPH oxidase NOX2 in prion pathogenesis |
| Q37508301 | The role of the unusual threonine string in the conversion of prion protein |
| Q35137829 | The sheddase ADAM10 is a potent modulator of prion disease. |
| Q27312083 | The strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of disease |
| Q27685314 | The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein |
| Q35866744 | Unaltered Prion Pathogenesis in a Mouse Model of High-Fat Diet-Induced Insulin Resistance |
| Q33531737 | Unexpected tolerance of alpha-cleavage of the prion protein to sequence variations |
| Q47288204 | Variable tau accumulation in murine models with abnormal prion protein deposits. |
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