scholarly article | Q13442814 |
P819 | ADS bibcode | 2009PLoSO...4.6707B |
P356 | DOI | 10.1371/JOURNAL.PONE.0006707 |
P932 | PMC publication ID | 2733036 |
P698 | PubMed publication ID | 19738901 |
P5875 | ResearchGate publication ID | 26797722 |
P50 | author | Adriano Aguzzi | Q375410 |
Jens Pahnke | Q59540336 | ||
Markus Tolnay | Q47157920 | ||
P2093 | author name string | Ivan Radovanovic | |
Markus Tolnay | |||
Thomas Rülicke | |||
Juliane Bremer | |||
Frank Baumann | |||
P2860 | cites work | Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection | Q24534939 |
Doppel-induced cerebellar degeneration in transgenic mice | Q24555049 | ||
NMR solution structure of the human prion protein | Q27620845 | ||
NMR structure of the human doppel protein | Q27640537 | ||
Perspectives: neurobiology. PrP's double causes trouble | Q28138888 | ||
Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel | Q28145970 | ||
Mice devoid of PrP are resistant to scrapie | Q28249108 | ||
Anchorless prion protein results in infectious amyloid disease without clinical scrapie | Q28254406 | ||
NEUROBIOLOGY:PrP's Double Causes Trouble | Q29544375 | ||
Novel proteinaceous infectious particles cause scrapie | Q29547678 | ||
Lethal recessive myelin toxicity of prion protein lacking its central domain | Q30478899 | ||
Scrapie-induced defects in learning and memory of transgenic mice expressing anchorless prion protein are associated with alterations in the gamma aminobutyric acid-ergic pathway | Q30484021 | ||
The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes | Q33390385 | ||
Prion strain discrimination based on rapid in vivo amplification and analysis by the cell panel assay | Q33455591 | ||
Absence of the prion protein homologue Doppel causes male sterility | Q34079215 | ||
NMR structure of the bovine prion protein isolated from healthy calf brains | Q34166383 | ||
Three-dimensional structures of prion proteins | Q34305023 | ||
Truncated Prion Protein and Doppel Are Myelinotoxic in the Absence of Oligodendrocytic PrPC | Q57083651 | ||
Cross-Linking Cellular Prion Protein Triggers Neuronal Apoptosis in Vivo | Q61463936 | ||
Pronuclear microinjection of mouse zygotes | Q79820188 | ||
Prion protein attenuates excitotoxicity by inhibiting NMDA receptors | Q81339233 | ||
Motor behavioral and neuropathological deficits in mice deficient for normal prion protein expression | Q34512335 | ||
Small is not beautiful: antagonizing functions for the prion protein PrP(C) and its homologue Dpl. | Q34536351 | ||
A cellular gene encodes scrapie PrP 27-30 protein | Q34557641 | ||
Cellular prion protein and caveolin-1 interaction in a neuronal cell line precedes Fyn/Erk 1/2 signal transduction. | Q35016910 | ||
Three-dimensional structures of the prion protein and its doppel | Q35122356 | ||
Games played by rogue proteins in prion disorders and Alzheimer's disease | Q35573421 | ||
Mammalian prion biology: one century of evolving concepts | Q35639302 | ||
Prion-induced amyloid heart disease with high blood infectivity in transgenic mice | Q35676392 | ||
Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth. | Q36321586 | ||
The functional links between prion protein and copper | Q36455641 | ||
Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain | Q39714572 | ||
Canine MDCK cell lines are refractory to infection with human and mouse prions | Q39990591 | ||
Dominant-negative effects of the N-terminal half of prion protein on neurotoxicity of prion protein-like protein/doppel in mice | Q40451562 | ||
Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region | Q40508891 | ||
Prion protein is a component of the multimolecular signaling complex involved in T cell activation. | Q40585109 | ||
Signal transduction through prion protein | Q40855079 | ||
Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. | Q41064177 | ||
The role of the octarepeat region in neuroprotective function of the cellular prion protein | Q42080796 | ||
Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125. | Q42976640 | ||
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein | Q43522858 | ||
Identification of the heparan sulfate binding sites in the cellular prion protein | Q43908316 | ||
Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation | Q44381518 | ||
Prion protein as trans-interacting partner for neurons is involved in neurite outgrowth and neuronal survival | Q44391055 | ||
Deletion of N-terminal residues 23-88 from prion protein (PrP) abrogates the potential to rescue PrP-deficient mice from PrP-like protein/doppel-induced Neurodegeneration | Q44448848 | ||
A human prion protein peptide (PrP59–91) protects against copper neurotoxicity | Q44600127 | ||
Doppel-induced Purkinje cell death is stoichiometrically abrogated by prion protein | Q47351716 | ||
Axonal swellings and degeneration in mice lacking the major proteolipid of myelin | Q48004959 | ||
A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination | Q48180328 | ||
Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions | Q48479400 | ||
Nearly ubiquitous tissue distribution of the scrapie agent precursor protein | Q48595206 | ||
Characterization of detergent-insoluble complexes containing the cellular prion protein and its scrapie isoform | Q48767220 | ||
Cell biology. Prion toxicity: all sail and no anchor | Q48872569 | ||
Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene | Q49010616 | ||
Normal host prion protein necessary for scrapie-induced neurotoxicity | Q49160879 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | prion protein family | Q24724413 |
P304 | page(s) | e6707 | |
P577 | publication date | 2009-09-07 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | Functionally relevant domains of the prion protein identified in vivo | |
P478 | volume | 4 |
Q34800606 | An N-terminal polybasic domain and cell surface localization are required for mutant prion protein toxicity |
Q46611794 | Ataxia with cerebellar lesions in mice expressing chimeric PrP-Dpl protein |
Q34538462 | Automated detection of amyloid-β-related cortical and subcortical signal changes in a transgenic model of Alzheimer's disease using high-field MRI. |
Q36432753 | Cellular prion protein: from physiology to pathology |
Q34922583 | Conserved roles of the prion protein domains on subcellular localization and cell-cell adhesion |
Q36481861 | Disease-associated mutations in the prion protein impair laminin-induced process outgrowth and survival |
Q40650405 | Domain-Specific Activation of Death-Associated Intracellular Signalling Cascades by the Cellular Prion Protein in Neuroblastoma Cells |
Q37093469 | Generating Bona Fide Mammalian Prions with Internal Deletions |
Q27308826 | Involvement of PrP(C) in kainate-induced excitotoxicity in several mouse strains |
Q46963608 | Membrane-anchored Aβ accelerates amyloid formation and exacerbates amyloid-associated toxicity in mice. |
Q38154145 | Myelin damage due to local quantitative abnormalities in normal prion levels: evidence from subacute combined degeneration and multiple sclerosis |
Q34074520 | Neurotoxic mutants of the prion protein induce spontaneous ionic currents in cultured cells |
Q47271332 | Prion protein inhibits fast axonal transport through a mechanism involving casein kinase 2. |
Q27312168 | The Structural Architecture of an Infectious Mammalian Prion Using Electron Cryomicroscopy |
Q42151993 | The alpha-secretase-derived N-terminal product of cellular prion, N1, displays neuroprotective function in vitro and in vivo |
Q33531737 | Unexpected tolerance of alpha-cleavage of the prion protein to sequence variations |
Q39638073 | Unraveling the neuroprotective mechanisms of PrP (C) in excitotoxicity |
Q27302091 | ZyFISH: a simple, rapid and reliable zygosity assay for transgenic mice |
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