scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.M404794200 |
P8608 | Fatcat ID | release_yicuz4mmxbcizo25yywlkhi5yu |
P698 | PubMed publication ID | 15459186 |
P50 | author | François Major | Q28875656 |
P2093 | author name string | Jing Yang | |
Peter Mastrangelo | |||
Joel C Watts | |||
Hans Kretzschmar | |||
Man-Sun Sy | |||
David Westaway | |||
Paul E Fraser | |||
Otto Windl | |||
Melissa Marvi | |||
Janaky Coomaraswamy | |||
Bettina Drisaldi | |||
Bob Strome | |||
Howard T J Mount | |||
Rosemary Ahrens | |||
M Azhar Chishti | |||
P2860 | cites work | Doppel-induced cerebellar degeneration in transgenic mice | Q24555049 |
Prions | Q24633319 | ||
Two different neurodegenerative diseases caused by proteins with similar structures | Q27630179 | ||
NMR structure of the human doppel protein | Q27640537 | ||
NMR structure of the mouse prion protein domain PrP(121-231) | Q27733163 | ||
Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform | Q27743024 | ||
Potential pseudoknots in the PrP-encoding mRNA | Q28205609 | ||
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis | Q28292299 | ||
Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein | Q28360418 | ||
The PrP-like protein Doppel binds copper | Q28506863 | ||
Copper stimulates endocytosis of the prion protein | Q28589040 | ||
Thermodynamic prediction of conserved secondary structure: application to the RRE element of HIV, the tRNA-like element of CMV and the mRNA of prion protein | Q48064053 | ||
Prion protein is necessary for normal synaptic function | Q48087355 | ||
Prions prevent neuronal cell-line death. | Q48152328 | ||
RNA molecules stimulate prion protein conversion | Q48170423 | ||
Small, highly structured RNAs participate in the conversion of human recombinant PrP(Sen) to PrP(Res) in vitro | Q48214478 | ||
Neurotoxicity of a prion protein fragment | Q48304223 | ||
Neurological illness in transgenic mice expressing a prion protein with an insertional mutation. | Q48308927 | ||
Identification of cryptic nuclear localization signals in the prion protein | Q48350176 | ||
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. | Q48373564 | ||
Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions | Q48479400 | ||
Induction of HO-1 and NOS in doppel-expressing mice devoid of PrP: implications for doppel function | Q48907389 | ||
Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene | Q49010616 | ||
Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice. | Q54037114 | ||
De novo generation of a PrPSc-like conformation in living cells. | Q54071895 | ||
Copper binding to the N-terminal tandem repeat regions of mammalian and avian prion protein. | Q55065425 | ||
Altered circadian activity rhythms and sleep in mice devoid of prion protein | Q59071240 | ||
Copper binding to the prion protein: structural implications of four identical cooperative binding sites | Q30558995 | ||
Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss | Q30876363 | ||
Copper(II)-induced conformational changes and protease resistance in recombinant and cellular PrP. Effect of protein age and deamidation | Q30881188 | ||
Mapping Cu(II) binding sites in prion proteins by diethyl pyrocarbonate modification and matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometric footprinting | Q32031203 | ||
Normal neurogenesis and scrapie pathogenesis in neural grafts lacking the prion protein homologue Doppel | Q33757335 | ||
Dominant-negative inhibition of prion formation diminished by deletion mutagenesis of the prion protein | Q33803953 | ||
Impairment of superoxide dismutase activation by N-terminally truncated prion protein (PrP) in PrP-deficient neuronal cell line | Q34221769 | ||
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein | Q34294957 | ||
The prion gene complex encoding PrP(C) and Doppel: insights from mutational analysis | Q34382758 | ||
Prion and doppel proteins bind to granule cells of the cerebellum | Q34416093 | ||
Small is not beautiful: antagonizing functions for the prion protein PrP(C) and its homologue Dpl. | Q34536351 | ||
Metal ions and prion diseases | Q34662087 | ||
Mammalian prion proteins: enigma, variation and vaccination | Q34691392 | ||
Structure and polymorphism of the mouse prion protein gene | Q35573850 | ||
Mammalian prion biology: one century of evolving concepts | Q35639302 | ||
Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation | Q36581272 | ||
Accumulation of protease-resistant prion protein (PrP) and apoptosis of cerebellar granule cells in transgenic mice expressing a PrP insertional mutation | Q36982880 | ||
Transgene-driven expression of the Doppel protein in Purkinje cells causes Purkinje cell degeneration and motor impairment | Q37074594 | ||
Molecular cloning and complete sequence of prion protein cDNA from mouse brain infected with the scrapie agent | Q37396908 | ||
Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus | Q37693769 | ||
Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain | Q39714572 | ||
Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia | Q39777445 | ||
The mechanism of internalization of glycosylphosphatidylinositol-anchored prion protein | Q39790846 | ||
Anterograde and retrograde intracellular trafficking of fluorescent cellular prion protein | Q40585724 | ||
Prion protein prevents human breast carcinoma cell line from tumor necrosis factor alpha-induced cell death | Q40595404 | ||
Intercellular transfer of the cellular prion protein | Q40700207 | ||
Prion protein protects human neurons against Bax-mediated apoptosis | Q40783610 | ||
Caspase-8 is required for cell death induced by expanded polyglutamine repeats. | Q40961806 | ||
Grand ideas floating freely. Conference on the new prion biology: basic science, diagnosis and therapy | Q43129135 | ||
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein | Q43522858 | ||
Ablation of the metal ion-induced endocytosis of the prion protein by disease-associated mutation of the octarepeat region | Q43645286 | ||
Differences between the prion protein and its homolog Doppel: a partially structured state with implications for scrapie formation | Q43897439 | ||
Essential role of the prion protein N terminus in subcellular trafficking and half-life of cellular prion protein. | Q44102009 | ||
Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol | Q44184139 | ||
Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation | Q44381518 | ||
Deletion of N-terminal residues 23-88 from prion protein (PrP) abrogates the potential to rescue PrP-deficient mice from PrP-like protein/doppel-induced Neurodegeneration | Q44448848 | ||
Cytosolic prion protein is not toxic and protects against Bax-mediated cell death in human primary neurons | Q44548892 | ||
Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication. | Q45979200 | ||
Release of the cellular prion protein from cultured cells after loss of its glycoinositol phospholipid anchor | Q46096263 | ||
Identification of glycoinositol phospholipid linked and truncated forms of the scrapie prion protein | Q46251858 | ||
Prion protein selectively binds copper(II) ions | Q46492410 | ||
Scrapie prion protein contains a phosphatidylinositol glycolipid | Q46814773 | ||
The N-terminal region of the prion protein ectodomain contains a lipid raft targeting determinant | Q47757000 | ||
P433 | issue | 53 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | apoptotic process | Q14599311 |
prion protein family | Q24724413 | ||
P304 | page(s) | 55443-55454 | |
P577 | publication date | 2004-09-29 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region | |
P478 | volume | 279 |