| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1016/S0968-0004(02)02106-0 |
| P8608 | Fatcat ID | release_tfkl66cwbjbrrdftkk2ddkelim |
| P698 | PubMed publication ID | 12069790 |
| P2093 | author name string | George A Carlson | |
| David Westaway | |||
| P2860 | cites work | Doppel-induced cerebellar degeneration in transgenic mice | Q24555049 |
| Ablation of the metal ion-induced endocytosis of the prion protein by disease-associated mutation of the octarepeat region | Q43645286 | ||
| XAFS study of the high-affinity copper-binding site of human PrP(91-231) and its low-resolution structure in solution | Q43699901 | ||
| Antibodies inhibit prion propagation and clear cell cultures of prion infectivity | Q46161882 | ||
| Pathologic conformations of prion proteins | Q46894080 | ||
| Expression of polyubiquitin and heat-shock protein 70 genes increases in the later stages of disease progression in scrapie-infected mouse brain. | Q47562532 | ||
| Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions | Q48479400 | ||
| Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity | Q48670908 | ||
| Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies | Q48800686 | ||
| Truncated forms of the human prion protein in normal brain and in prion diseases | Q48807964 | ||
| Induction of HO-1 and NOS in doppel-expressing mice devoid of PrP: implications for doppel function | Q48907389 | ||
| Copper binding to the N-terminal tandem repeat regions of mammalian and avian prion protein. | Q55065425 | ||
| A C-terminal-truncated PrP Isoform Is Present in Mature Sperm | Q57371794 | ||
| Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions | Q72421540 | ||
| Quantitative trait loci affecting prion incubation time in mice | Q73024760 | ||
| Prion protein binds copper within the physiological concentration range | Q73692926 | ||
| Identification of a novel gene encoding a PrP-like protein expressed as chimeric transcripts fused to PrP exon 1/2 in ataxic mouse line with a disrupted PrP gene | Q74126314 | ||
| Two different neurodegenerative diseases caused by proteins with similar structures | Q27630179 | ||
| Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel | Q28145970 | ||
| Prion diseases of humans and animals: their causes and molecular basis | Q28209943 | ||
| Mice devoid of PrP are resistant to scrapie | Q28249108 | ||
| Identification of interaction domains of the prion protein with its 37-kDa/67-kDa laminin receptor | Q28363055 | ||
| Electron paramagnetic resonance evidence for binding of Cu(2+) to the C-terminal domain of the murine prion protein | Q28367705 | ||
| Identification of candidate proteins binding to prion protein | Q28511061 | ||
| Copper stimulates endocytosis of the prion protein | Q28589040 | ||
| Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein | Q30778772 | ||
| Glycosylation differences between the normal and pathogenic prion protein isoforms | Q30810971 | ||
| Cleavage of the amino terminus of the prion protein by reactive oxygen species. | Q31520300 | ||
| Mapping Cu(II) binding sites in prion proteins by diethyl pyrocarbonate modification and matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometric footprinting | Q32031203 | ||
| Normal neurogenesis and scrapie pathogenesis in neural grafts lacking the prion protein homologue Doppel | Q33757335 | ||
| Upregulation of the genes encoding lysosomal hydrolases, a perforin-like protein, and peroxidases in the brains of mice affected with an experimental prion disease | Q33795125 | ||
| Metals and neuroscience. | Q33878376 | ||
| Transmissible and genetic prion diseases share a common pathway of neurodegeneration | Q33885223 | ||
| Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody | Q33930771 | ||
| Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein | Q34294957 | ||
| The prion gene complex encoding PrP(C) and Doppel: insights from mutational analysis | Q34382758 | ||
| A transmembrane form of the prion protein in neurodegenerative disease | Q34454961 | ||
| Normal prion protein has an activity like that of superoxide dismutase. | Q34505606 | ||
| Scrapie prions selectively modify the stress response in neuroblastoma cells | Q34520271 | ||
| Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice | Q35523444 | ||
| Prion protein-deficient neurons reveal lower glutathione reductase activity and increased susceptibility to hydrogen peroxide toxicity | Q35788165 | ||
| Identification of multiple quantitative trait loci linked to prion disease incubation period in mice | Q35939147 | ||
| Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry | Q36281890 | ||
| Doxycycline control of prion protein transgene expression modulates prion disease in mice | Q36527236 | ||
| Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies | Q36663046 | ||
| Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains | Q37057378 | ||
| Location and properties of metal-binding sites on the human prion protein. | Q37104327 | ||
| Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration | Q39646511 | ||
| Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain | Q39714572 | ||
| Prion protein protects human neurons against Bax-mediated apoptosis | Q40783610 | ||
| Signal transduction through prion protein | Q40855079 | ||
| Prion (PrPSc)-specific epitope defined by a monoclonal antibody | Q42816365 | ||
| A glycolipid-anchored prion protein is endocytosed via clathrin-coated pits. | Q43109950 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | prion protein family | Q24724413 |
| P1104 | number of pages | 7 | |
| P304 | page(s) | 301-307 | |
| P577 | publication date | 2002-06-01 | |
| P1433 | published in | Trends in Biochemical Sciences | Q1565711 |
| P1476 | title | Mammalian prion proteins: enigma, variation and vaccination | |
| P478 | volume | 27 |
| Q44392473 | Could inhibition of the proteasome cause mad cow disease? |
| Q40508891 | Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region |
| Q59053964 | Monoclonal antibodies inhibit prion replication and delay the development of prion disease |
| Q28210578 | Polymorphism at codon 174 of the prion-like protein gene is not associated with sporadic Alzheimer's disease |
| Q35622996 | Prions and the immune system: a journey through gut, spleen, and nerves |
| Q42817519 | Testing the possibility to protect bovine PrPC transgenic Swiss mice against bovine PrPSc infection by DNA vaccination using recombinant plasmid vectors harboring and expressing the complete or partial cDNA sequences of bovine PrPC. |
| Q42703327 | The octarepeat domain of the prion protein binds Cu(II) with three distinct coordination modes at pH 7.4. |
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