| meta-analysis | Q815382 |
| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1046281384 |
| P356 | DOI | 10.1038/GENE.2012.46 |
| P698 | PubMed publication ID | 23076337 |
| P5875 | ResearchGate publication ID | 232280646 |
| P50 | author | Saleh Ibrahim | Q43139623 |
| P2093 | author name string | J Zheng | |
| X Yu | |||
| F Petersen | |||
| P2860 | cites work | Confirmation of the genetic association of CTLA4 and PTPN22 with ANCA-associated vasculitis | Q21261514 |
| A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease | Q22251291 | ||
| PTPN22 gene regulates natural killer cell proliferation during in vitro expansion | Q24316976 | ||
| Cutting edge: the PTPN22 allelic variant associated with autoimmunity impairs B cell signaling | Q24318432 | ||
| Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4 | Q24538382 | ||
| Shared and distinct genetic variants in type 1 diabetes and celiac disease | Q24623113 | ||
| Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo | Q24629443 | ||
| Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus | Q24630434 | ||
| Genome-wide association study in alopecia areata implicates both innate and adaptive immunity | Q24632461 | ||
| Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants | Q24633806 | ||
| Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis | Q24635370 | ||
| Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease | Q27860821 | ||
| Recent advances in the genetics of autoimmune disease | Q28238782 | ||
| Protein tyrosine phosphatase PTPN22 in human autoimmunity | Q28242744 | ||
| Differential association of the PTPN22 coding variant with autoimmune diseases in a Dutch population | Q28248685 | ||
| A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes | Q28248848 | ||
| A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis | Q28267921 | ||
| Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. | Q28273794 | ||
| Association of the PTPN22 R620W polymorphism with anti-topoisomerase I- and anticentromere antibody-positive systemic sclerosis | Q28276277 | ||
| Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant | Q28280659 | ||
| PTPN22, PDCD1 and CYP27B1 polymorphisms and susceptibility to type 1 diabetes in Polish patients | Q28284060 | ||
| Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus | Q28289699 | ||
| Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus | Q28301821 | ||
| Association of R602W in a protein tyrosine phosphatase gene with a high risk of rheumatoid arthritis in a British population: evidence for an early onset/disease severity effect | Q28301839 | ||
| PEST domain-enriched tyrosine phosphatase (PEP) regulation of effector/memory T cells | Q28590230 | ||
| Genome-wide association analysis identifies three psoriasis susceptibility loci | Q28924376 | ||
| The R620W C/T polymorphism of the gene PTPN22 is associated with SLE independently of the association of PDCD1. | Q30160168 | ||
| The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dose-dependent manner but not with HLA-SE status | Q30160337 | ||
| Association of the lymphoid tyrosine phosphatase R620W variant with rheumatoid arthritis, but not Crohn's disease, in Canadian populations | Q33218161 | ||
| Susceptibility to type 1 diabetes conferred by the PTPN22 C1858T polymorphism in the Spanish population | Q33294087 | ||
| Prevalence of common disease-associated variants in Asian Indians. | Q33318138 | ||
| Defining the role of the MHC in autoimmunity: a review and pooled analysis | Q33330857 | ||
| The role of PTPN22 gene polymorphism in childhood immune thrombocytopenic purpura | Q33395420 | ||
| Lymphoid tyrosine phosphatase R620W variant and inflammatory bowel disease in Tunisia | Q33612241 | ||
| Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations | Q33653276 | ||
| Evaluation of the rheumatoid arthritis susceptibility loci HLA-DRB1, PTPN22, OLIG3/TNFAIP3, STAT4 and TRAF1/C5 in an inception cohort | Q33923376 | ||
| Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis | Q34110041 | ||
| The susceptibility loci juvenile idiopathic arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1 | Q34268514 | ||
| Primary sclerosing cholangitis: diagnosis and management | Q34498568 | ||
| Rheumatoid arthritis association with the FCRL3 -169C polymorphism is restricted to PTPN22 1858T-homozygous individuals in a Canadian population | Q34585615 | ||
| The association between the PTPN22 1858C>T variant and type 1 diabetes depends on HLA risk and GAD65 autoantibodies | Q34607188 | ||
| Association of functional variants of PTPN22 and tp53 in psoriatic arthritis: a case-control study | Q34896193 | ||
| Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients | Q34897145 | ||
| A single-nucleotide polymorphism in the gene encoding lymphoid protein tyrosine phosphatase (PTPN22) confers susceptibility to generalised vitiligo | Q46599062 | ||
| Testing for linkage and association with rheumatoid arthritis a ptpn22 promoter polymorphism reported to be associated and linked with type 1 diabetes in the Caucasian population | Q46599416 | ||
| C1858T functional variant of PTPN22 gene is not associated with celiac disease genetic predisposition | Q46660163 | ||
| Association of the PTPN22 C1858T single-nucleotide polymorphism with rheumatoid arthritis phenotypes in an inception cohort. | Q46689842 | ||
| PTPN22 C1858T polymorphism in Colombian patients with autoimmune diseases | Q46703705 | ||
| A case-control study of tyrosine phosphatase (PTPN22) confirms the lack of association with Crohn's disease | Q46704913 | ||
| The functional genetic variation in the PTPN22 gene has a negligible effect on the susceptibility to develop inflammatory bowel disease. | Q46721529 | ||
| A general autoimmunity gene (PTPN22) is not associated with inflammatory bowel disease in a British population | Q46721533 | ||
| Mutation screening of PTPN22: association of the 1858T-allele with Addison's disease | Q46732649 | ||
| The functional R620W variant of the PTPN22 gene is associated with celiac disease. | Q46808828 | ||
| Association between PTPN22 C1858T and type 1 diabetes: a replication in continental Italy | Q46819653 | ||
| The PTPN22 620W allele is a risk factor for Wegener's granulomatosis | Q46829597 | ||
| Sex-specific association of PTPN22 1858T with type 1 diabetes but not with Hashimoto's thyroiditis or Addison's disease in the German population | Q46831303 | ||
| The protein tyrosine phosphatase nonreceptor 22 (PTPN22) is associated with high GAD antibody titer in latent autoimmune diabetes in adults: Non Insulin Requiring Autoimmune Diabetes (NIRAD) Study 3. | Q46868313 | ||
| Evaluating the role of the 620W allele of protein tyrosine phosphatase PTPN22 in Crohn's disease and multiple sclerosis | Q46878243 | ||
| Association of PTPN22 1858C/T polymorphism with vitiligo susceptibility in Gujarat population. | Q46883159 | ||
| Sex-specific association of the human PTPN22 1858T-allele with type 1 diabetes. | Q46900842 | ||
| Association of the PTPN22*R620W polymorphism with autoimmune myasthenia gravis. | Q46912103 | ||
| Male restricted genetic association of variant R620W in PTPN22 with psoriatic arthritis | Q46926230 | ||
| Multiple sclerosis candidate autoantigens except myelin oligodendrocyte glycoprotein are transcribed in human thymus | Q48478016 | ||
| The 1858T PTPN22 gene variant contributes to a genetic risk of type 1 diabetes in a Ukrainian population. | Q51807268 | ||
| No independent role of the -1123 G>C and+2740 A>G variants in the association of PTPN22 with type 1 diabetes and juvenile idiopathic arthritis in two Caucasian populations. | Q51932778 | ||
| Haplotype analysis revealed no association between the PTPN22 gene and RA in a Japanese population. | Q51941868 | ||
| The autoimmune disease-associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness. | Q53225913 | ||
| The non-synonymous C1858T substitution in the PTPN22 gene is associated with susceptibility to the severe forms of alopecia areata. | Q54593087 | ||
| The PTPN22 R263Q polymorphism is a risk factor for rheumatoid arthritis in Caucasian case-control samples | Q57154867 | ||
| Evaluation of the genetic association of thePTPN22 R620W polymorphism in familial and sporadic systemic lupus erythematosus | Q57329891 | ||
| The 620W allele is the PTPN22 genetic variant conferring susceptibility to RA in a Dutch population | Q58234945 | ||
| Perifollicular and Perivascular Mouse Skin Mast Cells Express Corticotropin-Releasing Hormone Receptor | Q58273710 | ||
| Association of PTPN22 single nucleotide polymorphism with rheumatoid arthritis but not with allergic asthma | Q59697424 | ||
| Evaluating the role of the genetic variations of PTPN22, NFKB1, and FcGRIIIA genes in inflammatory bowel disease: A meta-analysis | Q60023315 | ||
| The PTPN22 1858T variant is not associated with primary biliary cirrhosis | Q61952453 | ||
| Association analysis of the PTPN22 gene in childhood-onset systemic lupus erythematosus in Mexican population | Q62658780 | ||
| Association of the PTPN22/LYP gene with type 1 diabetes | Q79281980 | ||
| The PTPN22 promoter polymorphism -1123G>C association cannot be distinguished from the 1858C>T association in a Norwegian rheumatoid arthritis material | Q80697518 | ||
| PTPN22 R620W polymorphism is not associated with pemphigus | Q81248122 | ||
| Systematic search for single nucleotide polymorphisms in a lymphoid tyrosine phosphatase gene (PTPN22): association between a promoter polymorphism and type 1 diabetes in Asian populations | Q82521460 | ||
| Association of the PTPN22 gene polymorphism with autoantibody positivity in Turkish rheumatoid arthritis patients | Q83911023 | ||
| Atherosclerosis and PTPN22: a study in coronary artery disease | Q84776732 | ||
| Protein tyrosine phosphatase gene C1858T allele confers risk for rheumatoid arthritis in Hungarian subjects | Q45129416 | ||
| The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease | Q45142894 | ||
| The autoimmunity-related polymorphism PTPN22 1858C/T is associated with anti-titin antibody-positive myasthenia gravis. | Q46030308 | ||
| No association of PTPN22 gene polymorphism with rheumatoid arthritis in Turkey | Q46055652 | ||
| PTPN22/LYP 1858C>T gene polymorphism and susceptibility to endometriosis in a Polish population | Q46112265 | ||
| PTPN22 allele polymorphisms in 15 Chinese populations | Q46221122 | ||
| Association analysis of the 1858C>T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases | Q46368513 | ||
| Protein tyrosine phosphatase gene (PTPN22) polymorphism in multiple sclerosis. | Q46375999 | ||
| Protein tyrosine phosphatase non-receptor type 22 gene variants at position 1858 are associated with type 1 and type 2 diabetes in Estonian population | Q46396187 | ||
| No evidence for association between 1858 C/T single-nucleotide polymorphism of PTPN22 gene and primary Sjögren's syndrome | Q46525705 | ||
| Association between the PTPN22 gene and rheumatoid arthritis and juvenile idiopathic arthritis in a UK population: further support that PTPN22 is an autoimmunity gene | Q46525978 | ||
| Lymphoid tyrosine phosphatase (PTPN22/LYP) variant and Graves' disease in a Polish population: association and gene dose-dependent correlation with age of onset | Q46534885 | ||
| PTPN22 R620W promotes production of anti-AChR autoantibodies and IL-2 in myasthenia gravis | Q46557023 | ||
| Association of the PTPN22 locus with rheumatoid arthritis in a New Zealand Caucasian cohort | Q46573581 | ||
| Variants of CARD15, TNFA and PTPN22 and susceptibility to Crohn's disease in the Czech population: high frequency of the CARD15 1007fs. | Q46588293 | ||
| Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship | Q34899429 | ||
| Association of PTPN22 1858T/T genotype with type 1 diabetes, Graves' disease but not with rheumatoid arthritis in Russian population. | Q35052064 | ||
| Association between the PTPN22 +1858 C/T polymorphism and psoriatic arthritis | Q35092932 | ||
| The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans | Q35187072 | ||
| Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci | Q35575555 | ||
| Lack of association between the protein tyrosine phosphatase non-receptor 22 (PTPN22)*620W allele and systemic sclerosis in the French Caucasian population | Q35637803 | ||
| Association of the PTPN22 R620W polymorphism with increased risk for SLE in the genetically homogeneous population of Crete | Q35854073 | ||
| Investigation of genetic variation across the protein tyrosine phosphatase gene in patients with rheumatoid arthritis in the UK. | Q35953254 | ||
| The protein tyrosine phosphatase N22 gene is associated with juvenile and adult idiopathic inflammatory myopathy independent of the HLA 8.1 haplotype in British Caucasian patients | Q36056490 | ||
| High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: mechanisms of selection of the self-reactive repertoire | Q36376026 | ||
| The PTPN22 1858C/T polymorphism is associated with anti-cyclic citrullinated peptide antibody-positive early rheumatoid arthritis in northern Sweden | Q36392280 | ||
| Polymorphisms in the PTPN22 region are associated with psoriasis of early onset. | Q36590346 | ||
| Pemphigus vulgaris and its active disease mouse model | Q37156240 | ||
| Association of common polymorphisms in known susceptibility genes with rheumatoid arthritis in a Slovak population using osteoarthritis patients as controls | Q37270770 | ||
| Genetic risk factors for rheumatoid arthritis differ in Caucasian and Korean populations | Q37406567 | ||
| Association between type 1 diabetes and GWAS SNPs in the southeast US Caucasian population | Q37634958 | ||
| Analysis of the influence of PTPN22 gene polymorphisms in systemic sclerosis | Q38367681 | ||
| The R620W polymorphism of the protein tyrosine phosphatase 22 gene in autoimmune thyroid diseases and rheumatoid arthritis in the Tunisian population | Q38936485 | ||
| Association of PTPN22 gene functional variants with development of pulmonary tuberculosis in Moroccan population | Q39158993 | ||
| No association of PTPN22 R620W gene polymorphism with rheumatic heart disease and systemic lupus erythematosus | Q40331696 | ||
| The PTPN22-1858C>T (R620W) functional polymorphism is associated with generalized vitiligo in the Romanian population | Q42164342 | ||
| Common and different genetic background for rheumatoid arthritis and coeliac disease | Q42629408 | ||
| Effects of PTPN22 C1858T polymorphism on susceptibility and clinical characteristics of British Caucasian rheumatoid arthritis patients. | Q42680902 | ||
| PTPN22 1858C>T polymorphism is strongly associated with rheumatoid arthritis but not with a response to methotrexate therapy | Q42871416 | ||
| The R620W polymorphism of the protein tyrosine phosphatase PTPN22 is not associated with multiple sclerosis | Q42949420 | ||
| Lack of association between ankylosing spondylitis and a functional polymorphism of PTPN22 proposed as a general susceptibility marker for autoimmunity | Q42955961 | ||
| Clinical characteristics and PTPN22 1858C/T variant analysis in Jordanian Arab vitiligo patients | Q43013127 | ||
| Increased representation of the PTPN22 mutation in patients with immune thrombocytopenia | Q43018677 | ||
| Genetic risk markers related to diabetes-associated autoantibodies in young patients with type 1 diabetes in berlin, Germany | Q43169308 | ||
| PTPN22 C1858T polymorphism in women with endometriosis | Q43195711 | ||
| The PTPN22 R620W polymorphism is not associated with systemic rheumatic diseases in South Africans. | Q43223025 | ||
| Association of PTPN22 C1858T and CTLA-4 A49G polymorphisms with Type 1 Diabetes in Croatians | Q43264945 | ||
| The PTPN22gain-of-function+1858T(+) genotypes correlate with low IL-2 expression in thymomas and predispose to myasthenia gravis | Q43289350 | ||
| Differential association of two PTPN22 coding variants with Crohn's disease and ulcerative colitis | Q43687514 | ||
| PTPN22 1858T is not a risk factor for North American pemphigus vulgaris | Q43883963 | ||
| Finnish case-control and family studies support PTPN22 R620W polymorphism as a risk factor in rheumatoid arthritis, but suggest only minimal or no effect in juvenile idiopathic arthritis | Q44449408 | ||
| The protein tyrosine phosphatase non-receptor type 22 C1858T polymorphism is a joint susceptibility locus for immunthyroiditis and autoimmune diabetes | Q44905066 | ||
| The tryptophan 620 allele of the lymphoid tyrosine phosphatase (PTPN22) gene predisposes to autoimmune Addison's disease. | Q44909176 | ||
| P433 | issue | 8 | |
| P921 | main subject | meta-analysis | Q815382 |
| P304 | page(s) | 641-652 | |
| P577 | publication date | 2012-10-18 | |
| P1433 | published in | Genes and Immunity | Q15745246 |
| P1476 | title | Meta-analysis reveals an association of PTPN22 C1858T with autoimmune diseases, which depends on the localization of the affected tissue | |
| P478 | volume | 13 |
| Q33591011 | A functional variant of PTPN22 confers risk for Vogt-Koyanagi-Harada syndrome but not for ankylosing spondylitis |
| Q51049627 | A polymorphism upstream MIR1279 gene is associated with pericarditis development in Systemic Lupus Erythematosus and contributes to definition of a genetic risk profile for this complication. |
| Q61450567 | Analysis of the rs2476601 polymorphism of PTPN22 in Mexican mestizo patients with leprosy |
| Q89792592 | Association of Functional Polymorphism in Protein Tyrosine Phosphatase Nonreceptor 22 (PTPN22) Gene with Vitiligo |
| Q64945528 | Association of PTPN22 polymorphism and its correlation with Graves' disease susceptibility in Polish adult population-A preliminary study. |
| Q38681399 | Associations between PTPN22 and TLR9 polymorphisms and systemic lupus erythematosus: a comprehensive meta-analysis |
| Q37108013 | Autoimmune vitiligo in rheumatic disease in the mestizo Mexican population |
| Q39022002 | C1858T Polymorphism of Protein Tyrosine Phosphatase Non-receptor Type 22 (PTPN22): an eligible target for prevention of type 1 diabetes? |
| Q64057927 | Cannabinoid Signaling in the Skin: Therapeutic Potential of the "C(ut)annabinoid" System |
| Q34671370 | Celiac disease as an autoimmune condition |
| Q26752647 | Concomitant Thyroid Disorders and Inflammatory Bowel Disease: A Literature Review |
| Q64102636 | Dual Role of PTPN22 but Not NLRP3 Inflammasome Polymorphisms in Type 1 Diabetes and Celiac Disease in Children |
| Q58793474 | Epigenome-wide DNA methylation regulates cardinal pathological features of psoriasis |
| Q37089325 | Genetic Association of PTPN22 Polymorphisms with Autoimmune Hepatitis and Primary Biliary Cholangitis in Japan |
| Q38276417 | Genetic Susceptibility to ANCA-Associated Vasculitis: State of the Art. |
| Q26783892 | Genetic studies of rheumatoid arthritis |
| Q39298145 | Genomics, transcriptomics and proteomics to elucidate the pathogenesis of rheumatoid arthritis |
| Q38657171 | Human Leukocyte Antigen-Disease Associations in Rheumatoid Arthritis |
| Q27006792 | Insights into type 1 diabetes from the autoimmune polyendocrine syndromes |
| Q58607423 | PTPN22 1858C>T polymorphism is associated with increased CD154 expression and higher CD4+ T cells percentage in rheumatoid arthritis patients |
| Q28387197 | PTPN22 R620W polymorphism and ANCA disease risk in white populations: a metaanalysis |
| Q42075872 | PTPN22 in autoimmunity: different cell and different way. |
| Q28606478 | PTPN22 is associated with susceptibility to psoriatic arthritis but not psoriasis: evidence for a further PsA-specific risk locus |
| Q35221741 | PTPN22: the archetypal non-HLA autoimmunity gene |
| Q56896678 | Potential role of PTPN22 in ankylosing spondylitis, comment on: associations of the PTPN22 and CTLA-4 genetic polymorphisms with Taiwanese ankylosing spondylitis |
| Q41953614 | Recent advances in genetic predisposition of myasthenia gravis |
| Q35775371 | Reduced incidence of Crohn's disease in systemic sclerosis: a nationwide population study. |
| Q91811501 | Regulation of CD4+ T Cell Signaling and Immunological Synapse by Protein Tyrosine Phosphatases: Molecular Mechanisms in Autoimmunity |
| Q38628322 | The Autoimmune Risk Variant PTPN22 C1858T Alters B Cell Tolerance at Discrete Checkpoints and Differentially Shapes the Naive Repertoire. |
| Q90207982 | The Contribution of PTPN22 to Rheumatic Disease |
| Q38788500 | The PTPN22 R263Q polymorphism confers protection against systemic lupus erythematosus and rheumatoid arthritis, while PTPN22 R620W confers susceptibility to Graves' disease in a Mexican population. |
| Q49399340 | The Protein Tyrosine Phosphatase Nonreceptor 22 (PTPN22) R620W Functional Polymorphism in Psoriasis |
| Q90301434 | The Role of Long Non-coding RNAs in the Pathogenesis of RA, SLE, and SS |
| Q64987239 | The association between rs2476601 polymorphism in PTPN22 gene and risk of alopecia areata: A meta-analysis of case-control studies. |
| Q34918378 | The effect of the autoimmunity-associated gene, PTPN22, on a BXSB-derived model of lupus |
| Q37054990 | The role of PTPN22 C1858T gene polymorphism in diabetes mellitus type 1: first evaluation in Greek children and adolescents |
| Q55001292 | The status of pulmonary fibrosis in systemic sclerosis is associated with IRF5, STAT4, IRAK1, and CTGF polymorphisms. |
| Q34039427 | Tyrosine phosphatase PTPN22: multifunctional regulator of immune signaling, development, and disease. |
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