scholarly article | Q13442814 |
P819 | ADS bibcode | 1991PNAS...88.8337K |
P356 | DOI | 10.1073/PNAS.88.19.8337 |
P8608 | Fatcat ID | release_w6k7adep7rhlvfaag2ahlmihre |
P932 | PMC publication ID | 52503 |
P698 | PubMed publication ID | 1924293 |
P5875 | ResearchGate publication ID | 21232283 |
P50 | author | Christine Disteche | Q88355920 |
P2093 | author name string | A E Karlsen | |
F J Grant | |||
D A Adler | |||
S Dube | |||
D Foster | |||
C E Grubin | |||
W A Hagopian | |||
H Bärmeier | |||
S Mathewes | |||
P2860 | cites work | Molecular cloning and amino acid sequence of brain L-glutamate decarboxylase | Q24556603 |
Expression of the neurotransmitter-synthesizing enzyme glutamic acid decarboxylase in male germ cells | Q24598227 | ||
A comprehensive set of sequence analysis programs for the VAX | Q26778432 | ||
A simple method for displaying the hydropathic character of a protein | Q26778481 | ||
Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer | Q27860572 | ||
Molecular Identification of the 62 kd Form of Glutamic Acid Decarboxylase from the Mouse | Q31095550 | ||
Pattern of expression of glutamic acid decarboxylase mRNA in the developing rat brain | Q33571925 | ||
Developmentally regulated expression of an exon containing a stop codon in the gene for glutamic acid decarboxylase | Q33890475 | ||
Characterization of a cDNA coding for rat glutamic acid decarboxylase | Q33943761 | ||
Autoantibodies to glutamic acid decarboxylase in a patient with stiff-man syndrome, epilepsy, and type I diabetes mellitus | Q34172103 | ||
gamma-Aminobutyric acid outside the mammalian brain | Q34372326 | ||
Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase | Q34566310 | ||
Stiff-man syndrome updated | Q34674686 | ||
Localization of a lymphocyte-specific protein tyrosine kinase gene (lck) at a site of frequent chromosomal abnormalities in human lymphomas | Q37401701 | ||
High Concentration of GABA and High Glutamate Decarboxylase Activity in Rat Pancreatic Islets and Human Insulinoma | Q40023366 | ||
GABA and pancreatic beta-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion. | Q41080795 | ||
Autoantibodies to GABA-ergic neurons and pancreatic beta cells in stiff-man syndrome | Q41196484 | ||
Evidence for two distinct forms of native glutamic acid decarboxylase in rat brain soluble extract: an immunoblotting study | Q41480565 | ||
The distribution of glutamate decarboxylase and aspartate transaminase in subcellular fractions of rat and guinea-pig brain | Q41956002 | ||
Characterization of three kinetically distinct forms of glutamate decarboxylase from pig brain | Q41977044 | ||
Viable purified islets of Langerhans from collagenase-perfused human pancreas | Q42042694 | ||
Purification and characterization of glutamate decarboxylase from mouse brain | Q42234469 | ||
Autoimmunity in stiff man syndrome | Q43504795 | ||
Sequences homologous to glutamic acid decarboxylase cDNA are present on mouse chromosomes 2 and 10. | Q43995153 | ||
Characterization of the proteins purified with monoclonal antibodies to glutamic acid decarboxylase | Q44184394 | ||
Two forms of the gamma-aminobutyric acid synthetic enzyme glutamate decarboxylase have distinct intraneuronal distributions and cofactor interactions. | Q45935043 | ||
Chemical and physical properties of Escherichia coli glutamate decarboxylase | Q47781018 | ||
Kinetically different, multiple forms of glutamate decarboxylase in rat brain | Q48205970 | ||
Glutamic acid decarboxylase cDNA: nucleotide sequence encoding an enzymatically active fusion protein | Q48213614 | ||
Chemical properties of Escherichia coli lysine decarboxylase including a segment of its pyridoxal 5'-phosphate binding site. | Q54033619 | ||
Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins | Q57449719 | ||
Antibodies to a Mr-64000 islet cell protein in Swedish children with newly diagnosed Type 1 (insulin-dependent) diabetes | Q61861667 | ||
Messenger RNA for myosin polypeptides: isolation from single myogenic cell cultures | Q67548624 | ||
Effects of sodium butyrate on proliferation-dependent insulin gene expression and insulin release in glucose-sensitive RIN-5AH cells | Q67687949 | ||
64,000 Mr autoantibodies as predictors of insulin-dependent diabetes | Q68088864 | ||
Revelation of specificity of 64K autoantibodies in IDDM serums by high-resolution 2-D gel electrophoresis. Unambiguous identification of 64K target antigen | Q69530151 | ||
Crystallization and properties of glutamate decarboxylase from Escherichia coli strain w+ | Q69826254 | ||
Isolation of viable islets of Langerhans from collagenase-perfused canine and human pancreata | Q70168098 | ||
Microdetermination of free amino acids in pancreatic islets isolated from obese-hyperglycemic mice | Q93744670 | ||
P433 | issue | 19 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 8337-8341 | |
P577 | publication date | 1991-10-01 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10 | |
P478 | volume | 88 |
Q33282777 | A -243A-->G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged White subjects. |
Q52545232 | A neural gene from Drosophila melanogaster with homology to vertebrate and invertebrate glutamate decarboxylases. |
Q53357215 | A new solid-phase radioimmunoassay to detect anti-GAD65 autoantibodies. |
Q73081435 | A novel high-throughput method for accurate, rapid, and economical measurement of multiple type 1 diabetes autoantibodies |
Q61861656 | A novel radioligand binding assay to determine diagnostic accuracy of isoform-specific glutamic acid decarboxylase antibodies in childhood IDDM |
Q41982714 | A signal located within amino acids 1-27 of GAD65 is required for its targeting to the Golgi complex region |
Q47815857 | A simple and rapid microSepharose assay for GAD65 and ICA512 autoantibodies in diabetes. Diabetes Incidence Study in Sweden (DISS). |
Q48144733 | Absence of autoantibodies against glutamate decarboxylase (GAD) in the non-obese diabetic (NOD) mouse and low expression of the enzyme in mouse islets |
Q50918709 | Age governs gender-dependent islet cell autoreactivity and predicts the clinical course in childhood IDDM. |
Q74229022 | Age of onset, not type of onset, affects the positivity and evanescence of IA-2 antibody |
Q22253174 | Alternative splicing of GAD67 results in the synthesis of a third form of glutamic-acid decarboxylase in human islets and other non-neural tissues |
Q36853549 | An islet-cell protein tyrosine phosphatase is a likely precursor to the 37-kDa autoantigen in type 1 diabetes: human and macaque sequences, tissue distribution, unique and shared epitopes, and predictive autoantibodies |
Q50056608 | Antiglutamic acid decarboxylase 65 (GAD65) antibody-associated epilepsy. |
Q70731822 | Assignment of the rat genes coding for dopa decarboxylase (DDC) and glutamic acid decarboxylases (GAD1 and GAD2) |
Q71788167 | Association between Antibodies to the MR 67,000 Isoform of Glutamate Decarboxylase (GAD) and Type 1 (Insulin-Dependent) Diabetes Mellitus with Coexisting Autoimmune Polyendocrine Syndrome Type II |
Q36954438 | Association of the -243A>G, +61450C>A Polymorphisms of the Glutamate Decarboxylase 2 (GAD2) Gene with Obesity and Insulin Level in North Indian Population |
Q48303867 | Autoantigenic reactivity of diabetes sera with a hybrid glutamic acid decarboxylase GAD67-65 molecule GAD67(1-101)/GAD65(96-585). |
Q40575830 | Autoantigens in type 1 diabetes mellitus |
Q28363451 | Autoimmune type 1 diabetes: resolved and unresolved issues |
Q36202374 | Autoreactive epitopes defined by diabetes-associated human monoclonal antibodies are localized in the middle and C-terminal domains of the smaller form of glutamate decarboxylase |
Q48499309 | Binding of antibodies in sera from Type 1 (insulin-dependent) diabetic patients to glutamate decarboxylase from rat tissues. Evidence for antigenic and non-antigenic forms of the enzyme |
Q50972009 | Calretinin inputs are confined to motoneurons for upward eye movements in monkey. |
Q34159440 | Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes |
Q57148226 | Characteristics of in-vitro phenotypes of glutamic acid decarboxylase 65 autoantibodies in high-titre individuals |
Q36695291 | Characterization of a linear epitope within the human pancreatic 64‐kDa glutamic acid decarboxylase and its autoimmune recognition by sera from insulin‐dependent diabetes mellitus patients |
Q41005356 | Characterization of self-glutamic acid decarboxylase 65-reactive CD4+ T-cell clones established from Japanese patients with insulin-dependent diabetes mellitus |
Q40416734 | Circulating Zonulin Correlates with Density of Enteroviruses and Tolerogenic Dendritic Cells in the Small Bowel Mucosa of Celiac Disease Patients |
Q37297817 | Cloning and characterization of myr 6, an unconventional myosin of the dilute/myosin-V family |
Q45803169 | Comparative effectiveness of antinociceptive gene therapies in animal models of diabetic neuropathic pain |
Q44886848 | Complexity of human immune response profiles for CD4+ T cell epitopes from the diabetes autoantigen GAD65. |
Q45057620 | Conformation-dependent GAD65 autoantibodies in diabetes |
Q37299778 | Decreased GAD65 mRNA levels in select subpopulations of neurons in the cerebellar dentate nuclei in autism: an in situ hybridization study. |
Q33899197 | Demonstration of GAD-65 as the main immunogenic isoform of glutamate decarboxylase in type 1 diabetes and determination of autoantibodies using a radioligand produced by eukaryotic expression |
Q34111857 | Detection of pancreatic islet 64,000 M(r) autoantigens in insulin-dependent diabetes distinct from glutamate decarboxylase |
Q38353381 | Diagnostic sensitivity of immunodominant epitopes of glutamic acid decarboxylase (GAD65) autoantibodies in childhood IDDM. |
Q48391409 | Differential effect of fasting on hypothalamic expression of genes encoding neuropeptide Y, galanin, and glutamic acid decarboxylase |
Q59649758 | Enzymatic and structural aspects on glutamate decarboxylase |
Q78849136 | Expression of endocrine autoantibodies in chronic hepatitis C, before and after interferon-alpha therapy |
Q61995630 | Expression of glutamic acid decarboxylase (GAD) in the α, β and δ cells of normal and diabetic pancreas: implications for the pathogenesis of type I diabetes |
Q41079519 | Expression of glutamic acid decarboxylase during human neuronal differentiation: studies using the NTera-2 culture system |
Q40575836 | GAD, diabetes, and Stiff-Man syndrome: some progress and more questions |
Q30430711 | GAD65 antibodies, chronic psychosis, and type 2 diabetes mellitus |
Q36137876 | GAD65 autoantibodies and its role as biomarker of Type 1 diabetes and Latent Autoimmune Diabetes in Adults (LADA). |
Q37358994 | GAD65 autoimmunity-clinical studies. |
Q42507827 | GAD65-mediated glutamate decarboxylation reduces glucose-stimulated insulin secretion in pancreatic beta cells. |
Q36505520 | Genes in the GABA Pathway Increase in the Lateral Thalamus of Sprague-Dawley Rats During the Proestrus/Estrus Phase |
Q33946742 | Genetic association analysis of behavioral inhibition using candidate loci from mouse models |
Q36361272 | Glutamic acid decarboxylase 67-reactive T cells: a marker of insulin-dependent diabetes |
Q37255494 | Glutamic acid decarboxylase autoantibodies in preclinical insulin-dependent diabetes |
Q44879677 | HLA class II is associated with the frequency of glutamic acid decarboxylase M(r) 65,000 autoantibodies in Japanese patients with insulin-dependent diabetes mellitus |
Q33848973 | HLA genes, islet autoantibodies and residual C-peptide at the clinical onset of type 1 diabetes mellitus and the risk of retinopathy 15 years later |
Q36777541 | HSV vector-mediated GAD67 suppresses neuropathic pain induced by perineural HIV gp120 in rats through inhibition of ROS and Wnt5a |
Q35235094 | High-affinity binding of short peptides to major histocompatibility complex class II molecules by anchor combinations |
Q70567569 | Human autoantibodies react with glutamic acid decarboxylase antigen in human and rat but not in mouse pancreatic islets |
Q36330292 | Humoral autoimmunity in type 1 diabetes: prediction, significance, and detection of distinct disease subtypes |
Q28288007 | ICA69 is expressed equally in the human endocrine and exocrine pancreas |
Q41994256 | Identification of a dominant epitope of glutamic acid decarboxylase (GAD-65) recognized by autoantibodies in stiff-man syndrome |
Q35634978 | Immune intervention yes, but for what reason, for whom, when and how? |
Q28087365 | Immunogenetics of type 1 diabetes mellitus |
Q44435975 | Improved in planta expression of the human islet autoantigen glutamic acid decarboxylase (GAD65). |
Q42487438 | Increased risk for endocrine autoimmunity in Italian type 2 diabetic patients with GAD65 autoantibodies |
Q48337407 | Intra-accumbens infusions of antisense oligodeoxynucleotides to one isoform of glutamic acid decarboxylase mRNA, GAD65, but not to GAD67 mRNA, impairs sustained attention performance in the rat. |
Q72429393 | Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes |
Q47706880 | Inverse relationship between GAD65 antibody levels and severe retinopathy in younger type 1 diabetic patients |
Q40569816 | Involvement of the proteasome in IL-1beta induced suppression of islets of Langerhans in the rat. |
Q46115645 | Islet cell antibodies (ICA) identify autoimmunity in children with new onset diabetes mellitus negative for other islet cell antibodies |
Q35824175 | Islet cell cytoplasmic autoantibody reactivity to glutamate decarboxylase in insulin-dependent diabetes |
Q38300551 | Isolation by anion-exchange of immunologically and enzymatically active human islet glutamic acid decarboxylase 65 overexpressed in Sf9 insect cells |
Q43830332 | Lack of association of glutamate decarboxylase 2 gene polymorphisms with severe obesity in utah |
Q36533216 | Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain |
Q48393344 | Molecular biology of IDDM. |
Q78059978 | NOD background genes influence T cell responses to GAD 65 in HLA-DQ8 transgenic mice |
Q39774757 | Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401. |
Q30808583 | Nucleotide sequence and chromosomal assignment of a cDNA encoding the large isoform of human glutamate decarboxylase |
Q47711606 | Peptide specificity of high-titer anti-glutamic acid decarboxylase (GAD)65 autoantibodies |
Q33907374 | Plant aromatic L-amino acid decarboxylases: evolution, biochemistry, regulation, and metabolic engineering applications |
Q36117948 | Prediction and prevention of type 1 diabetes: update on success of prediction and struggles at prevention |
Q24307746 | Preparation of a rat brain histidine decarboxylase (HDC) cDNA probe by PCR and assignment of the human HDC gene to chromosome 15 |
Q43924655 | Preservation of enzyme activity and antigenicity after mutagenesis of the membrane anchoring domain of GAD65. |
Q33902290 | Prevalence of autoantibodies to the 65- and 67-kD isoforms of glutamate decarboxylase in insulin-dependent diabetes mellitus |
Q36532404 | Primary structure and cellular localization of chicken brain myosin-V (p190), an unconventional myosin with calmodulin light chains |
Q41131246 | Quantitative analysis of islet glutamic acid decarboxylase p64 autoantibodies in insulin-dependent diabetes mellitus |
Q24617932 | Quantitative assay using recombinant human islet glutamic acid decarboxylase (GAD65) shows that 64K autoantibody positivity at onset predicts diabetes type |
Q34051132 | Secretagogin is a Ca2+-binding protein identifying prospective extended amygdala neurons in the developing mammalian telencephalon |
Q40473381 | Self and non-self antigen in diabetic autoimmunity: Molecules and mechanisms |
Q54588538 | Stabilization of recombinantly expressed proteins. |
Q57449587 | T Cell Proliferative Responses to Glutamic Acid Decarboxylase-65 in IDDM are Negatively Associated with HLA DR3/4 |
Q42724811 | TCR-like antibodies distinguish conformational and functional differences in two- versus four-domain auto reactive MHC class II-peptide complexes |
Q40934733 | The TATA-less rat GAD65 promoter can be activated by Sp1 through non-consensus elements |
Q73486424 | Transgenic plants expressing autoantigens fed to mice to induce oral immune tolerance |
Q24307858 | Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene |
Q35934762 | Type 1 diabetes as a model for prediction and diagnosis |
Q35004343 | Vaccination against type 1 diabetes |