The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection

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The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1000379
P932PMC publication ID2660273
P698PubMed publication ID19360122
P5875ResearchGate publication ID24271595

P50authorMoshe ArditiQ16147367
Timothy R CrotherQ59683649
David M UnderhillQ37385896
P2093author name stringKenichi Shimada
Shuang Chen
Ellena Peterson
Rosalinda Sorrentino
Terence M Doherty
Anatoly V Slepenkin
Paul W Dempsey
Randa Alsabeh
P2860cites workNod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaBQ22010046
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systemsQ24292468
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detectionQ24292675
Nod1-mediated endothelial cell activation by Chlamydophila pneumoniaeQ24338210
Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxinQ24539124
Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptorsQ24629037
L,L-diaminopimelate aminotransferase, a trans-kingdom enzyme shared by Chlamydia and plants for synthesis of diaminopimelate/lysineQ24674785
Chlamydia pneumoniaeand atherosclerosisQ54063686
Nod1 Participates in the Innate Immune Response toPseudomonas aeruginosaQ57245053
RICK/RIP2 Mediates Innate Immune Responses Induced through Nod1 and Nod2 but Not TLRsQ57275903
IFN- Enhances Production of Nitric Oxide from Macrophages via a Mechanism That Depends on Nucleotide Oligomerization Domain-2Q61905389
Defective Phagocytosis and Clearance of Pseudomonas aeruginosa in the Lung Following Bone Marrow TransplantationQ61942141
An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathwaysQ28139919
Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kappaBQ28142782
Involvement of receptor-interacting protein 2 in innate and adaptive immune responsesQ28207221
Chlamydia pneumoniae and atherosclerosisQ28237111
Chlamydia pneumoniae inclusion membrane protein Cpn0585 interacts with multiple Rab GTPasesQ28251473
Signalling pathways and molecular interactions of NOD1 and NOD2Q28298636
Nitric oxide and macrophage functionQ29615327
Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycanQ29618544
A mouse model of Chlamydia pneumoniae strain TWAR pneumonitisQ33596734
Chlamydial infection in inducible nitric oxide synthase knockout miceQ33751943
Characterization of a neutralizing monoclonal antibody directed at the lipopolysaccharide of Chlamydia pneumoniae.Q33758389
Intracellular survival by ChlamydiaQ34156271
Neutrophil granulocytes--Trojan horses for Leishmania major and other intracellular microbes?Q34202144
Mechanisms of pathogenesis: evasion of killing by polymorphonuclear leukocytesQ34276259
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity islandQ34359740
IFN-gamma production by antigen-presenting cells: mechanisms emerge.Q34382913
NOD-LRR proteins: role in host-microbial interactions and inflammatory diseaseQ34426050
In vitro and in vivo functional activity of Chlamydia MurA, a UDP-N-acetylglucosamine enolpyruvyl transferase involved in peptidoglycan synthesis and fosfomycin resistanceQ34514901
The role of IFN-gamma in the outcome of chlamydial infectionQ34712661
The intracellular life of chlamydiaeQ35030148
Chlamydia pneumoniae (TWAR).Q35367697
Role of atypical bacterial infection of the lung in predisposition/protection of asthma.Q35697038
Chlamydia pneumoniae--an infectious risk factor for atherosclerosis?Q35701591
Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivoQ36227882
Morphologic and antigenic characterization of interferon gamma-mediated persistent Chlamydia trachomatis infection in vitroQ36275624
Building the invisible wall: updating the chlamydial peptidoglycan anomalyQ36368411
Amphiphysin IIm is required for survival of Chlamydia pneumoniae in macrophagesQ36402455
Intracellular pattern recognition receptors in the host responseQ36528528
The cytosolic pattern recognition receptor NOD1 induces inflammatory interleukin-8 during Chlamydia trachomatis infectionQ36747056
Muramic acid is not detectable in Chlamydia psittaci or Chlamydia trachomatis by gas chromatography-mass spectrometry.Q36978668
Functional and biochemical analysis of Chlamydia trachomatis MurC, an enzyme displaying UDP-N-acetylmuramate:amino acid ligase activityQ37051672
Interaction of chlamydiae and host cells in vitroQ37056842
Role of toll-like receptors in immune responses to chlamydial infectionsQ37108497
Chlamydia causes fragmentation of the Golgi compartment to ensure reproduction.Q37856042
Chlamydia pneumoniae-induced foam cell formation requires MyD88-dependent and -independent signaling and is reciprocally modulated by liver X receptor activationQ37856309
Chlamydia pneumoniae--induced macrophage foam cell formation is mediated by Toll-like receptor 2.Q37860795
Stimulation of the cytosolic receptor for peptidoglycan, Nod1, by infection with Chlamydia trachomatis or Chlamydia muridarum.Q37862344
Differential involvement of TLR2 and TLR4 in host survival during pulmonary infection with Chlamydia pneumoniaeQ37862553
MyD88 is pivotal for the early inflammatory response and subsequent bacterial clearance and survival in a mouse model of Chlamydia pneumoniae pneumoniaQ37864592
Polymorphonuclear neutrophils improve replication of Chlamydia pneumoniae in vivo upon MyD88-dependent attractionQ37865116
Heat shock protein 60 from Chlamydia pneumoniae elicits an unusual set of inflammatory responses via Toll-like receptor 2 and 4 in vivoQ37866477
Intracellular bacterial infection-induced IFN-gamma is critically but not solely dependent on Toll-like receptor 4-myeloid differentiation factor 88-IFN-alpha beta-STAT1 signalingQ37867184
Macrophages, CD4+ or CD8+ cells are each sufficient for protection against Chlamydia pneumoniae infection through their ability to secrete IFN-gammaQ37867764
Chlamydia pneumoniae survival in macrophages is regulated by free Ca2+ dependent reactive nitrogen and oxygen speciesQ37869878
Role of chlamydial heat shock protein 60 in the stimulation of innate immune cells by Chlamydia pneumoniaeQ37871262
Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathwayQ37872780
IFN-alpha beta-dependent, IFN-gamma secretion by bone marrow-derived macrophages controls an intracellular bacterial infectionQ37873063
Regulation and role of IFN-gamma in the innate resistance to infection with Chlamydia pneumoniaeQ37876677
Role of innate and adaptive immunity in the outcome of primary infection with Chlamydia pneumoniae, as analyzed in genetically modified mice.Q37878887
Chlamydia: old ideas crushed, new mysteries baredQ37879640
Antibiotics, peptidoglycan synthesis and genomics: the chlamydial anomaly revisitedQ37879887
A Chlamydia pneumoniae component that induces macrophage foam cell formation is chlamydial lipopolysaccharideQ37879971
Type III secretion genes identify a putative virulence locus of ChlamydiaQ37882492
Inhibition of intracellular multiplication of human strains of Chlamydia trachomatis by nitric oxideQ37883224
The immunobiology and immunopathology of chlamydial infectionsQ37886284
Ultrastructural lung pathology of experimental Chlamydia pneumoniae pneumonitis in miceQ37888544
Chlamydia pneumoniae IgG antibody prevalence in south-western and eastern Finland in 1982 and 1987.Q37889391
Gamma interferon-induced nitric oxide production reduces Chlamydia trachomatis infectivity in McCoy cells.Q37891650
Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cellsQ40382473
Nucleotide-binding oligomerization domain protein 2-deficient mice control infection with Mycobacterium tuberculosisQ42277166
The relation between Chlamydia pneumoniae and atherosclerosisQ42390881
Deoxyribonucleic Acid Relatedness of Chlamydia sp. Strain TWAR to Chlamydia trachomatis and Chlamydia psittaciQ45311678
Receptor-interacting protein-2 deficiency delays macrophage migration and increases intracellular infection during peritoneal dialysis-associated peritonitisQ46529733
NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2.Q46942398
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectChlamydophila pneumoniaeQ132319
P304page(s)e1000379
P577publication date2009-04-10
P1433published inPLOS PathogensQ283209
P1476titleThe NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection
P478volume5

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