Modifications to the peptidoglycan backbone help bacteria to establish infection

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Modifications to the peptidoglycan backbone help bacteria to establish infection is …
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scholarly articleQ13442814

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P356DOI10.1128/IAI.00651-10
P932PMC publication ID3028845
P698PubMed publication ID21041496
P5875ResearchGate publication ID47644781

P50authorJeffrey N WeiserQ37378150
P2093author name stringKimberly M Davis
P2860cites workNod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaBQ22010046
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaBQ24290546
Genetic evidence that antibacterial activity of lysozyme is independent of its catalytic functionQ24291768
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systemsQ24292468
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detectionQ24292675
Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involvedQ24295020
Ultrastructural localization of lysozyme in human neutrophils by immunogoldQ24298836
Distribution of Lysosomal Enzymes, Cationic Proteins, and Bactericidal Substances in Subcellular Fractions of Human Polymorphonuclear LeukocytesQ24300614
RIP2 is a novel NF-kappaB-activating and cell death-inducing kinaseQ24310179
Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxinQ24539124
NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosisQ24811631
Human Peptidoglycan Recognition Protein-L Is an N-Acetylmuramoyl-L-alanine AmidaseQ28115452
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's diseaseQ28201834
Functional characterization of the peptide transporter PEPT2 in primary cultures of human upper airway epitheliumQ28300707
Increased inflammation in lysozyme M-deficient mice in response to Micrococcus luteus and its peptidoglycanQ28511228
PGLYRP-2 and Nod2 are both required for peptidoglycan-induced arthritis and local inflammationQ28587573
A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptideQ28589654
Critical role of NOD2 in regulating the immune response to Staphylococcus aureusQ28593011
Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2Q28646106
Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycanQ29618544
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acidQ29620015
Peptidoglycan recognition proteins are a new class of human bactericidal proteinsQ29871532
A mammalian peptidoglycan recognition protein with N-acetylmuramoyl-L-alanine amidase activityQ31147483
A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune systemQ33268810
Resistance to mucosal lysozyme compensates for the fitness deficit of peptidoglycan modifications by Streptococcus pneumoniaeQ33392682
Oxidative stress-induced peptidoglycan deacetylase in Helicobacter pyloriQ33400222
The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infectionQ33429029
In vivo transcriptional profiling of Listeria monocytogenes and mutagenesis identify new virulence factors involved in infectionQ33455499
NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosisQ33478396
Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretionQ33640502
Specificity of the autolysin of Streptococcus (Diplococcus) pneumoniaeQ33793950
Requirement for capsule in colonization by Streptococcus pneumoniaeQ34007742
Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognitionQ34166263
Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2.Q34215657
Peptidoglycan N-acetylglucosamine deacetylase, a putative virulence factor in Streptococcus pneumoniaeQ34261872
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity islandQ34359740
Primary structure of the peptidoglycan-derived tracheal cytotoxin of Bordetella pertussisQ34449142
Cross-linked peptidoglycan mediates lysostaphin binding to the cell wall envelope of Staphylococcus aureusQ34514398
Significant contribution of the pgdA gene to the virulence of Streptococcus suisQ34874722
The presence of peptidoglycan O-acetyltransferase in various staphylococcal species correlates with lysozyme resistance and pathogenicityQ34975810
Mechanism of action of penicillin: triggering of the pneumococcal autolytic enzyme by inhibitors of cell wall synthesisQ35092585
Two bactericidal targets for penicillin in pneumococci: autolysis-dependent and autolysis-independent killing mechanismsQ35245445
Modification of the structure of peptidoglycan is a strategy to avoid detection by nucleotide-binding oligomerization domain protein 1.Q35689331
Strain-related differences in lysozyme sensitivity and extent of O-acetylation of gonococcal peptidoglycanQ36332054
Membrane location of a deoxyribonuclease implicated in the genetic transformation of Diplococcus pneumoniaeQ36611400
Peptidoglycan recognition proteins: pleiotropic sensors and effectors of antimicrobial defencesQ36761177
Neisseria gonorrhoeae uses two lytic transglycosylases to produce cytotoxic peptidoglycan monomersQ36845577
Structural variation in the glycan strands of bacterial peptidoglycanQ37028275
Arthropathic properties of gonococcal peptidoglycan fragments: implications for the pathogenesis of disseminated gonococcal diseaseQ37029625
Cell envelope stress response in Gram-positive bacteriaQ37049377
Strain distribution in extents of lysozyme resistance and O-acetylation of gonococcal peptidoglycan determined by high-performance liquid chromatographyQ37101759
The TLR2-MyD88-NOD2-RIPK2 signalling axis regulates a balanced pro-inflammatory and IL-10-mediated anti-inflammatory cytokine response to Gram-positive cell wallsQ37139051
Increased NOD2-mediated recognition of N-glycolyl muramyl dipeptideQ37292790
pH-dependent internalization of muramyl peptides from early endosomes enables Nod1 and Nod2 signalingQ37358204
Helicobacter pylori-mediated transcriptional regulation of the human beta-defensin 2 gene requires NF-kappaB.Q39567005
Clathrin- and dynamin-dependent endocytic pathway regulates muramyl dipeptide internalization and NOD2 activationQ39870668
The linkage between teichoic acid and peptidoglycan in bacterial cell wallsQ39876706
Binding and Cellular Activation Studies Reveal That Toll-like Receptor 2 Can Differentially Recognize Peptidoglycan from Gram-positive and Gram-negative BacteriaQ39891823
Structure of the linkage units between ribitol teichoic acids and peptidoglycanQ39966380
Nod1 mediates cytoplasmic sensing of combinations of extracellular bacteriaQ40138263
Contribution of phagocytosis and intracellular sensing for cytokine production by Staphylococcus aureus-activated macrophagesQ40205815
hPepT1 transports muramyl dipeptide, activating NF-kappaB and stimulating IL-8 secretion in human colonic Caco2/bbe cellsQ40497021
Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniaeQ40542030
Enterococcus faecalis constitutes an unusual bacterial model in lysozyme resistanceQ41904091
Influence of wall teichoic acid on lysozyme resistance in Staphylococcus aureus.Q41905397
Mutations affecting peptidoglycan acetylation in Neisseria gonorrhoeae and Neisseria meningitidisQ42949822
A helix-loop-helix peptide at the upper lip of the active site cleft of lysozyme confers potent antimicrobial activity with membrane permeabilization actionQ43740251
Mucosal clearance of capsule-expressing bacteria requires both TLR and nucleotide-binding oligomerization domain 1 signalingQ44289699
Penicillin enhances the toll-like receptor 2-mediated proinflammatory activity of Streptococcus pneumoniae.Q44598925
Mouse Lysozyme M Is Important in Pulmonary Host Defense againstKlebsiella pneumoniaeInfectionQ44655799
Capsular expression in Streptococcus pneumoniae negatively affects spontaneous and antibiotic-induced lysis and contributes to antibiotic toleranceQ44727665
The glycopeptide vancomycin does not enhance toll-like receptor 2 (TLR2) activation by Streptococcus pneumoniae.Q44931231
Identification of the namH gene, encoding the hydroxylase responsible for the N-glycolylation of the mycobacterial peptidoglycanQ45136861
Why are pathogenic staphylococci so lysozyme resistant? The peptidoglycan O-acetyltransferase OatA is the major determinant for lysozyme resistance of Staphylococcus aureusQ45231397
Cationic polypeptides are required for antibacterial activity of human airway fluid.Q45946168
The pgdA gene encodes for a peptidoglycan N-acetylglucosamine deacetylase in Streptococcus pneumoniaeQ47865657
Covalent linkage between the capsular polysaccharide and the cell wall peptidoglycan of Streptococcus pneumoniae revealed by immunochemical methods.Q52241543
The wall peptidoglycans of Neisseria perflava, Moraxella glucidolytica, Pseudomonas alcaligenes and Proteus vulgaris strain P18.Q54014930
Muramylpeptide shedding modulates cell sensing of Shigella flexneri.Q54430471
Glucosamine substitution and muramidase susceptibility in Bacillus anthracis.Q54475192
Multiple antibiotic resistance in a bacterium with suppressed autolytic system.Q54677814
Attenuation of penicillin resistance in a peptidoglycan O-acetyl transferase mutant of Streptococcus pneumoniaeQ57077244
Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cellsQ57272367
RICK/RIP2 Mediates Innate Immune Responses Induced through Nod1 and Nod2 but Not TLRsQ57275903
Induction of Nod2 in Myelomonocytic and Intestinal Epithelial Cells via Nuclear Factor-κB ActivationQ59383486
SpxB RegulatesO-Acetylation-dependent Resistance ofLactococcus lactisPeptidoglycan to HydrolysisQ60181267
Serotypic variations among virulent pneumococci in deposition and degradation of covalently bound C3b: implications for phagocytosis and antibody productionQ70018803
Identification of 2-amino-2-deoxyglucose residues in the peptidoglucan of Streptococcus pneumoniaeQ70508178
Digestion of Streptococcus pneumoniae cell walls with its major peptidoglycan hydrolase releases branched stem peptides carrying proinflammatory activityQ77353720
The peptidoglycan-degrading property of lysozyme is not required for bactericidal activity in vivoQ79755027
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)562-570
P577publication date2010-11-01
P1433published inInfection and ImmunityQ6029193
P1476titleModifications to the peptidoglycan backbone help bacteria to establish infection
P478volume79

Reverse relations

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