Adenylation enzyme characterization using gamma -(18)O(4)-ATP pyrophosphate exchange

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Adenylation enzyme characterization using gamma -(18)O(4)-ATP pyrophosphate exchange is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CHEMBIOL.2009.04.007
P932PMC publication ID2710614
P698PubMed publication ID19477411
P5875ResearchGate publication ID26248623

P50authorVanessa PhelanQ42884098
Brian O. BachmannQ86531308
P2093author name stringYu Du
John A McLean
P2860cites workShotgun metabolomics approach for the analysis of negatively charged water-soluble cellular metabolites from mouse heart tissueQ24605698
Specificity prediction of adenylation domains in nonribosomal peptide synthetases (NRPS) using transductive support vector machines (TSVMs)Q24811842
Directed evolution can rapidly improve the activity of chimeric assembly-line enzymesQ33290356
Profiling and imaging of tissues by imaging ion mobility-mass spectrometryQ33290372
MALDI imaging mass spectrometry: molecular snapshots of biochemical systemsQ33300677
Isotopic ( 18 O) shift in 31 P nuclear magnetic resonance applied to a study of enzyme-catalyzed phosphate—phosphate exchange and phosphate (oxygen)—water exchange reactionsQ33555779
The specificity-conferring code of adenylation domains in nonribosomal peptide synthetasesQ34504359
Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.Q34555236
Benzodiazepine biosynthesis in Streptomyces refuineus.Q34640414
Roles of the two lysyl-tRNA synthetases of Escherichia coli: analysis of nucleotide sequences and mutant behaviorQ36165206
Cloning and characterization of the gene for Escherichia coli tryptophanyl-transfer ribonucleic acid synthetaseQ36309193
Methods for kinetic and thermodynamic analysis of aminoacyl-tRNA synthetasesQ36528700
Characterization of tyrocidine synthetase 1 (TY1): requirement of posttranslational modification for peptide biosynthesisQ36707406
Aryl acid adenylating enzymes involved in siderophore biosynthesis: fluorescence polarization assay, ligand specificity, and discovery of non-nucleoside inhibitors via high-throughput screening.Q37125144
45 Tyrocidine synthetase systemQ39933988
Identification and characterization of a type II peptidyl carrier protein from the bleomycin producer Streptomyces verticillus ATCC 15003.Q41681873
Facile detection of acyl and peptidyl intermediates on thiotemplate carrier domains via phosphopantetheinyl elimination reactions during tandem mass spectrometryQ42126323
Molecular characterization of the genes of actinomycin synthetase I and of a 4-methyl-3-hydroxyanthranilic acid carrier protein involved in the assembly of the acylpeptide chain of actinomycin in StreptomycesQ42599723
Role of sulfhydryl groups in activating enzymes. Properties of Escherichia coli lysine-transfer ribonucleic acid synthetaseQ44540959
Mass spectrometric interrogation of thioester-bound intermediates in the initial stages of epothilone biosynthesisQ44880733
Liquid chromatographic analysis of nucleosides and their mono-, di- and triphosphates using porous graphitic carbon stationary phase coupled with electrospray mass spectrometryQ44999544
Alkyne-functionalized chemical probes for assaying the substrate specificities of the adenylation domains in nonribosomal peptide synthetasesQ46261302
Manipulation of carrier proteins in antibiotic biosynthesisQ46269994
Molecular mechanisms underlying nonribosomal peptide synthesis: approaches to new antibiotics.Q51542466
Reactions catalyzed by mature and recombinant nonribosomal peptide synthetases.Q51636993
On the rate law and mechanism of the adenosine triphosphate--pyrophosphate isotope exchange reaction of amino acyl transfer ribonucleic acid synthetases.Q53010631
Tryptophanyl transfer ribonucleic acid synthetase of Escherichia coli. I. Purification of the enzyme and of tryptrophan transfer ribonucleic acid.Q53737847
An optimized ATP/PP(i)-exchange assay in 96-well format for screening of adenylation domains for applications in combinatorial biosynthesisQ56898544
Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domainsQ56901837
Kinetic techniques for the investigation of amino acid: tRNA ligases (aminoacyl-tRNA synthetases, amino acid activating enzymes)Q68695199
CONVERSION OF MONO- AND OLIGODEOXYRIBONUCLEOTIDES TO 5-TRIPHOSPHATESQ78347150
P433issue5
P304page(s)473-478
P577publication date2009-05-01
P1433published inChemistry and BiologyQ15758410
P1476titleAdenylation enzyme characterization using gamma -(18)O(4)-ATP pyrophosphate exchange
P478volume16

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cites work (P2860)
Q42076043A continuous kinetic assay for adenylation enzyme activity and inhibition
Q34400837An environmental bacterial taxon with a large and distinct metabolic repertoire
Q33787584Anthranilate-activating modules from fungal nonribosomal peptide assembly lines
Q91993694Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering
Q46913126Biosynthesis of phenylnannolone A, a multidrug resistance reversal agent from the halotolerant myxobacterium Nannocystis pusilla B150.
Q38675125Biosynthesis of polyketides by trans-AT polyketide synthases
Q37764802Biosynthesis, synthesis, and biological activities of pyrrolobenzodiazepines
Q38944415Characterisation of taxlllaids A-G; natural products from Xenorhabdus indica.
Q40443040Comparative chemical screening and genetic analysis reveal tentoxin as a new virulence factor in Cochliobolus miyabeanus, the causal agent of brown spot disease on rice.
Q89940898HAMA: a multiplexed LC-MS/MS assay for specificity profiling of adenylate-forming enzymes
Q47342001Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq-Signaling Inhibitor FR900359.
Q35117610Identification and biosynthesis of a novel xanthomonadin-dialkylresorcinol-hybrid from Azoarcus sp. BH72.
Q41617637Measurement of Nonribosomal Peptide Synthetase Adenylation Domain Activity Using a Continuous Hydroxylamine Release Assay
Q92643155Modification and de novo design of non-ribosomal peptide synthetases using specific assembly points within condensation domains
Q48265481Online Pyrophosphate Assay for Analyzing Adenylation Domains of Nonribosomal Peptide Synthetases
Q49166734Quantifying Kinase-Specific Phosphorylation Stoichiometry Using Stable Isotope Labeling In a Reverse In-Gel Kinase Assay.
Q37687428Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination

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